Complement System
The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.
Found 191 products for "Complement System".
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Vilobelimab
CAS:Vilobelimab (CaCP-29, IFX-1), a monoclonal antibody, inhibits C5a to reduce inflammation and is researched in sepsis and COVID-19 studies.Purity:99% (SDS-PAGE); 98.9% (SEC-HPLC) - 99% (SDS-PAGE); 98.9% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.86 kDa (Predicted)Sutimlimab
CAS:Sutimlimab: monoclonal antibody, inhibits complement protein C1, treats cold agglutinin-induced hemolysis.Purity:> 95%Color and Shape:Transparent LiquidMolecular weight:144.8 kDa (Predicted)Vesencumab
CAS:Vesencumab (MNRP-1685A) is an IG1 antibody targeting NRP-1 with anti-angiogenic and anti-tumor activity. Vesencumab can be used to study solid tumors.Purity:99.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 99.2% (SDS-PAGE); 96.6% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.22 kDa (Predicted)Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Formula:C22H29FO5Purity:98% - 99.91%Color and Shape:Crystals From Ether (Ntp 1992)Molecular weight:392.46Tesidolumab
CAS:Tesidolumab, a fully human IgG1/λ anti-C5 monoclonal antibody, inhibits crovalimab and C5, preventing membrane attack complex formation.Purity:99.72% (SEC-HPLC) - > 95%Color and Shape:Transparent LiquidMolecular weight:144.16 kDa (Predicted)Avdoralimab
CAS:Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting complement C5a receptor 1 (C5aR1).Purity:>95%Color and Shape:Transparent LiquidMolecular weight:145.9 kDa (Predicted)PMX 205 acetate
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).Formula:C47H66N10O8Purity:99.4%Color and Shape:SolidMolecular weight:899.09Lampalizumab
CAS:Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Factor D, which can be used in cardiovascular disease research.Purity:>95%Color and Shape:LiquidMolecular weight:143.8 kDa (Predicted)Cyclosporin A
CAS:Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.Formula:C62H111N11O12Purity:99.00% - 99.94%Color and Shape:White SolidMolecular weight:1202.61SB290157 trifluoroacetate
CAS:SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).Formula:C24H29F3N4O6Purity:98.93% - 99.98%Color and Shape:White SolidMolecular weight:526.5055Ravulizumab
CAS:Ravulizumab (ALXN1210) is a humanized antibody for blocking complement activation, treating PNH, aHUS, and myasthenia gravis.Purity:> 95%Color and Shape:Transparent LiquidMolecular weight:145.80 kDa (Predicted)JPE-1375
CAS:JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Formula:C49H63FN10O9Color and Shape:SolidMolecular weight:955.0845Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Formula:C68H100F3N23O19S2Color and Shape:SolidMolecular weight:1664.79PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Formula:C47H65N11O7Purity:98%Color and Shape:SolidMolecular weight:896.09AMY-101
CAS:AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.Formula:C83H117N23O18S2Purity:98%Color and Shape:SolidMolecular weight:1789.11TLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Formula:C107H170N40O26Purity:98%Color and Shape:SolidMolecular weight:2432.75Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated C3 inhibitory peptide used in complement regulation and C3-mediated immune pathway research.Formula:(C2H4O)nC170H248N50O47S4·xC2H4O2Purity:97.10%Color and Shape:Odour SolidMolecular weight:1501.7ARC186
ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.Color and Shape:SolidMolecular weight:120702.76Factor B-IN-1
CAS:Factor B-IN-1 is a Factor B inhibitor.Formula:C19H16N4O2Color and Shape:SolidMolecular weight:332.3559PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Formula:C71H123N19O21S2·xC2HF3O2Color and Shape:Solid
