Carbohydrates and glycoconjugates

<p>The P1-antigen is a blood group antigen that is encoded by the gene. It is synthesized as a precursor protein of approximately 150 amino acids that undergoes proteolytic processing to generate two peptides, A and B, which are attached to the cell surface. The P1-antigen has been shown to be involved in transcriptional regulation and antimicrobial activity. It has also been shown to be present in metastatic colorectal cancer cells and its expression can be induced by trypsin treatment. The P1-antigen is also one of the most frequently studied proteins for its role in immune responses against bacteria, viruses, and parasites. This protein has been found to have response elements for several transcription factors including NF-κB, AP-1, NFAT, SP-1, and STAT3. The basic structure of this protein contains a diode region with two negatively charged regions that are critical for its function.</p>

<p>4-O-(b-D-Galactopyranosyl)-D-glucosamine HCl is a synthetic, water soluble, non-digestible oligosaccharide. It has regulatory effects on the utilisation of glucose and lacto-n-neotetraose by various cells in vitro. This compound also inhibits the development of intestinal pathogens in humans and elucidates their sequence specificity. 4-O-(b-D-Galactopyranosyl)-D-glucosamine HCl is used to study the role of this molecule in infant nutrition.</p>

<p>Difucosyl-para-lacto-N-hexaose III is a custom synthesis. It is an oligosaccharide that belongs to the class of polysaccharides. It has a molecular weight of 1,000 Da and contains two monosaccharides: difucose and para-lactohexose. This product can be modified with fluorination or click chemistry. Difucosyl-para-lacto-N-hexaose III has a purity of &gt; 98% and CAS No., which is 93794-37-5.</p>

<p>4-Methoxyphenyl 6-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosylonate)-2,3 -di O benzyl b D galactopyranoside is a modified oligosaccharide that is synthesized from the sugar galactose. The methyl group on the 4 position of the phenol end of the molecule is substituted with an acetamide group to form 4 methoxyphenyl 6 O (methyl 5 acetamido 4 7 8 9 tetra O acetyl 3 5 dideoxy D glycero a D galacto 2 nonulopyranosylonate)-2 3 di O benzyl b D galactopyranoside. This molecule has been fluorinated at the 2 and 3 positions</p>

<p>GNA2 N-glycan is a custom-synthesized modified oligosaccharide that is a complex carbohydrate. It is a high purity, methylated and glycosylated polysaccharide sugar with fluorination. GNA2 N-glycan has CAS No. 1295-70-1 and is monosaccharide. It has a molecular weight of 266.</p>

<p>Benzyl 2-acetamido-2-deoxy-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-a-D galactopyranoside is a complex carbohydrate with a CAS number of 8632784. It is an oligosaccharide that is modified with methylation and glycosylation. This molecule has a molecular weight of 907.19 and the purity level is high at 99%. This product can be used for fluoroquinolone resistance research or as an intermediate for other chemical modifications.</p>

<p>Octyl 2-acetamido-2-deoxy-b-D-glucopyranosyl-(1-2)-a-D-mannopyranosyl-(1-2)-b-D-glucopyranoside is a custom synthetic sugar that is used in the synthesis of complex carbohydrates. This product has been fluorinated to give it a high level of purity and is available for purchase at CAS No. 1268248-67-4. Octyl 2 acetamido 2 deoxy b D glucopyranosyl (1 2) a D mannopyranosyl (1 2) b D glucopyranoside has been modified with methylation, Click modification, and glycosylation. It can be used in polysaccharide synthesis or glycosylation reactions to produce polysaccharides with different properties.</p>

<p>Tetra-O-benzyl-4-O-(2,3-di-O-benzyl-4,6-O-benzylidene)-a-D-mannopyranosyl)-b-D-glucopyranoside is a carbohydrate that has been modified with fluorination and methylation. It is a saccharide with an oligosaccharide group, which is attached to the 1-, 2-, 3-, 6-, and 4'-positions of the sugar. This product is synthesized by custom synthesis and is available in high purity. Tetra-O-benzyl-4-O-(2,3-di-O--benzyl--4,6--O--benzylidene)-a--D--mannopyranosyl)-b--D--glucopyranoside can be used as a glycosylation or click modification agent.</p>

<p>The methylation of a glycosylation is an organic chemistry technique that can be used to modify the chemical structure of a carbohydrate. A glycosylation is the reaction between an alcohol and a sugar, which produces a glycoside. The addition of methyl groups at specific positions on the sugar molecule can lead to improved properties such as increased stability, increased solubility, or increased uptake by cells. This process has been shown to produce compounds with more desirable pharmacological properties than their parent compounds. Click chemistry is a versatile and powerful method for modifying carbohydrates. It involves the use of copper-catalyzed azide-alkyne cycloaddition reactions to form carbon-nitrogen bonds in place of conventional amide linkages in peptides and proteins. Carbohydrates are modified using this method by attaching small molecules such as fluorine atoms onto one or more carbons in the carbohydrate structure. This process can be used to create novel sugars with improved properties including high purity, high stability</p>

<p>Iso-lacto-N-neooctaose is a prebiotic oligosaccharide that can be found in breast milk. Iso-lacto-N-neooctaose is a carbohydrate molecule with a high degree of polymerisation that is resistant to digestion by human enzymes, which means it reaches the gut microbiota where it can stimulate the growth of beneficial bifidobacteria. Iso-lacto-N-neooctaose has been shown to have bioactive properties in humans and infants, including antihypertensive effects, antiulcerogenic effects, and immunomodulatory effects. Studies have also shown that this compound may help prevent colorectal cancer by increasing the population of bifidobacteria in the colon.</p>

<p>Benzyl 4-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-2,3-di-O-benzylb -D-galactopyranoside is a Fluorination and Glycosylation product. It is a Custom Synthesis of Monosaccharide and Oligosaccharide. The CAS number for this product is 106835-99-8.</p>

<p>Lactose-sp-biotin is a complex carbohydrate that has been modified with biotin. It is synthesized by the click modification of lactose and spacer arm, followed by glycosylation with biotin. Lactose-sp-biotin is soluble in water, which makes it suitable for use as a food additive. This product can also be used for labeling and identification of biomolecules in various fields such as fluorescence, immunoassay, or immunohistochemistry.</p>

<p>Disialylated pentaose type I (DSI-1) is a disaccharide sugar that is synthesized in high purity by custom synthesis. It is a complex carbohydrate that consists of five monosaccharides: glucose, galactose, mannose, fucose and N-acetylneuraminic acid. DSI-1 has been shown to have glycosylation and methylation activity. This product has been modified with fluorination and saccharide modification, as well as Click chemistry. Disialylated pentaose type I is used in the pharmaceutical industry as an intermediate for the production of glycoconjugates and in the food industry to produce artificial sweeteners.</p>

<p>3'-a-Sialyl-N-acetyllactosamine-PAA-biotin is a biotin labelled sialylglycoside</p>

<p>Pinoresinol diglucopyranoside is a natural compound found in Chinese herb. It has been shown to have an anti-atherosclerotic effect, which may be due to the inhibition of nuclear factor kappa-light-chain-enhancer (NF-κB) and matrix metalloproteinase (MMP)-9. Pinoresinol diglucopyranoside also inhibits collagenase activity in vitro and reduces inflammation in vivo. The molecular mechanism of this compound may involve the toll-like receptor 4 (TLR4) pathway, which is responsible for immune responses to bacterial products. Pinoresinol diglucopyranoside has been shown to inhibit the transcription and polymerization of DNA by binding to DNA gyrase and topoisomerase IV, respectively.</p>

<p>N-Acetylneuraminic acid pentamer penta sodium is a modification of the N-acetylneuraminic acid monomer. It is a carbohydrate that is made up of five saccharide units linked by glycosidic bonds. The first four saccharides are N-acetylneuraminic acid and the fifth unit is D-mannose. This molecule has been synthesized for use as a vaccine adjuvant to increase the body's immune response to vaccines.</p>

<p>1,3,4,6-Tetra-O-acetyl-2-O-(2,3,4-tri-O-benzoyl-a-L-fucopyranosyl)-a-D-galactopyranose is a high purity, custom synthesis of an oligosaccharide consisting of a complex carbohydrate. The saccharide is modified with methylation and glycosylation. This product has been fluorinated and synthesized through the Click chemistry.</p>

<p>GM1a pentasaccharide (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with a single sialic acid residue linked α2,3 to the inner galactose residue (Ledeen, 2009). GM1a pentasaccharide is the carbohydrate moiety in GM1a ganglioside which interacts and modulates tyrosine kinases, such as, neural tropomyosin receptor kinase A (TrkA), by inducing the release of neurotrophins from fibroblast cells and the epidermal growth factor receptor (EGFR) (Higuero, 2009). Oligosaccharide domain of monosialylated glycosphingolipid GM1 of a-series that specifically interacts with cholera toxin B subunit (CBT) from V. cholerae, heat-labile toxin B subunit (LTB) from E. coli and alpha toxin from C. perfrigens. This ganglioside is abundant in nervous system as well as in other peripheral tissues (Chiricozzi, 2020).</p>

<p>Benzyl 2-acetamido-3-O-(2,3,4-tri-O-benzyl-a-L-fucopyranosyl)-4,6-O-benzylidene-2-deoxy-a-D-glucopyranoside is a high purity custom synthesis sugar. This compound has been synthesized by Click modification of the amino acid glycoside and fluorination of the sugar. It is an Oligosaccharide with a saccharide chain composed of Monosaccharides and Carbohydrates. The CAS number for this compound is 196941 – 73 – 8.</p>

<p>Man-8 N-glycan is a modification of the carbohydrate Man-8. It is a complex carbohydrate that is synthesized from monosaccharides and polysaccharides. This product has been custom synthesized for high purity and high quality. It has been fluorinated to increase its stability, and it can be used in glycosylation reactions.</p>

<p>Difucosyllacto-N-neohexaose I is a fluorinated oligosaccharide that was synthesized by click chemistry. The synthesis of this compound involved the addition of a methyl group to the penultimate carbon on the reducing end of a disaccharide. Fluorination was then performed to introduce a trifluoromethyl group onto the sugar ring, which is an important step in obtaining a high level of purity. This compound has been shown to be effective in inhibiting bacterial growth and can be used as an antibacterial agent for prevention and treatment of various infections.</p>

<p>a-Heptasaccharide is a complex carbohydrate that is synthesized from glycerol and seven monosaccharides. It is used in the synthesis of other carbohydrates and as a fluorination reagent.</p>

<p>4-Methoxyphenyl 4-O-{4-O-[2,4-di-O-(3,4,6-tri-O-Ac-2-PhthN -bDGlc)-3,6-di-O-(3,4,6,-tri-OAc)aDMan]-bDMan} 3,6 di O-(3,4,6,-tri Ac) a D Man] 2 PhthN b D Glc} 6 O (tri Ac) a L Fuc} 2 PhthN b D Glc} 3 O Bn 6 O (tri Ac) a L Fuc} 2 PhthN b D Glc} is an oligosaccharide. It is custom synthesized to include methylation and glycosylation modifications. This product is for use in research only and should not be used in humans.</p>

<p>Lacto-N-neotetraosa-APD-HSA is a synthetic monosaccharide that is structurally similar to tetrasaccharide and pentasaccharide. It can be synthesized by click chemistry and has been modified by fluorination and acetylation. Lacto-N-neotetraosa-APD-HSA has a high purity and is an excellent candidate for applications in the food industry, such as sugar substitutes.</p>

<p>2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy-a-D-galactopyranosyl serine (GalNAc) is a synthetic carbohydrate that contains a biotin moiety. It is synthesized by the glycosylation of 2,3,4,6 tetraacetamido sugar with 2,3,4,6 tetraacetamido sugar and 1,2,3 octaacetamido sugar. The product can be modified with methyl or fluorine groups to make it more reactive in click chemistry. This product has been shown to have high purity and can be used in custom synthesis projects.</p>

<p>GlcNPhth[346Ac]b(1-3)Gal[246Bn]-b-MP is a complex carbohydrate that is derivatized with methyl, click, and fluorination. It has been modified with saccharides, oligosaccharides, and monosaccharides to create a custom synthesis. This product is available for purchase at the desired purity level. GlcNPhth[346Ac]b(1-3)Gal[246Bn]-b-MP is Glycosylated, Methylated, Clicked, Polysaccharide Fluorinated Saccharide Modified with Oligosaccharide Synthetic CAS No Monosaccharide Custom Synthesis High Purity.</p>

<p>Sucrose 1,6,6'-tricarboxylic acid trimethyl ester is a carbohydrate that has been fluorinated and methylated. It is a synthetic sugar that can be custom synthesized by our chemists to meet your specifications. This product is very pure and has a high degree of purity. It can be used as an oligosaccharide or as a monosaccharide in glycosylation or methylation reactions. Sucrose 1,6,6'-tricarboxylic acid trimethyl ester is also known as sucrose 3-fluoro-3-methylbutyrate, CAS No. 289711-92-8, or C12H18O7F3.</p>

<p>Gangliotriose is the core trisaccharide structure in gangliosides, such as, GD2 (GalNAcβ1,4Galβ1,4Glc) (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that posess: self-renewal properties (division without disrupting the undifferentiated state), and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>4-O-Acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-1,2-ethyledine (CAS No. 230953-17) is a carbohydrate that has been modified with acetyl groups at the 3 and 6 positions of the monosaccharide unit. This modification is a complex carbohydrate that is made up of oligosaccharides and polysaccharides. The modification causes changes in the chemical properties of the carbohydrate compared to natural saccharides. 4-O-(2,3,4,6) tetra O acetyl a D mannopyranosyl 1 2 ethyledine b D mannopyranose has been used in synthesis of custom sugars for medical applications. It has also shown anti inflammatory activities against Mycobacterium tuberculosis and Mycobacterium avium complex</p>

<p>Benzyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-a-D-glucopyranoside is a custom synthesis, complex carbohydrate. It is an Oligosaccharide, Polysaccharide that has been modified and glycosylated. It has a CAS number of 81243-70-1. This product's purity is high and it is fluorinated. The product is synthetic and contains sugar.</p>

<p>1,3:1,4 b-Glucotriose (A) is a custom synthesis that is available with a purity of ≥98%. It is a fluorinated polysaccharide with a complex structure that can be modified to produce different variations. The methylation status of the compound can be customized as well. This product is an oligosaccharide and polysaccharide sugar that contains one glucose unit. It has been synthesized from the monosaccharide sugar and it can be used for chemical modification or for research purposes.</p>

<p>Paromamine trihydrochloride is a Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification of the chemical compound. Paromamine trihydrochloride is an Oligosaccharide and saccharide that has been Glycosylated. The Carbohydrate complex is made up of a number of sugar units that are linked together to form a polysaccharide. This Polysaccharide can be found in many plants and animals.</p>

<p>Heparin is a polysaccharide consisting of repeating units of glucosamine and glucuronic acid that has been shown to have anti-coagulant, antithrombotic, and anti-inflammatory properties. Heparin disaccharide III-H disodium salt is a heparin disaccharide that has been modified by the addition of sodium ions. This heparin disaccharide has been shown to inhibit the proliferation of leukaemia cells in vitro, which may be due to its inhibition of DNA synthesis or cell cycle progression. The mechanism by which this heparin disaccharide inhibits cell growth is not yet known. Research into this mechanism could lead to new treatments for cancer and other diseases.</p>

<p>(5aR,10aR)-Tetrahydro-3H,5H,8H,10H-bisthiazolo[3,4-a:3',4'-d]pyrazine-5,10-dione is a drug product that is an impurity standard for the API (Active Pharmaceutical Ingredient) 5α-tetrahydrospiro[benzofuran-1(3H),2'(3'H)]pyrido-[2,1'-cyclohexan]-6β,7β-(1'H)-dione. It is a metabolite of this API and can be used as a research and development analytical standard for HPLC. The CAS number for this compound is 72744-67-3. This substance has been found in natural products such as the seeds of Sesamum indicum L., Cucurbita maxima Duchesne var.</p>

<p>Ganglioside GM3 (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked a2,3 to the galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain and melanomas where it is over expressed. It is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganlioside is implicated in various other diseases involving chronic inflammation, such as, insulin resistance, leptin resistance, T-cell function and immune disorders (e.g. allergic asthma). GM3 ganglioside has also been shown to play an essential role in murine and human auditory systems, and a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).</p>

<p>The H-BSA-15-atom spacer is a synthetic polymer that can be modified to create a glycolipid or glycopeptide. The H-BSA-15-atom spacer is an oligosaccharide with a molecular weight of 3,500 daltons and has been custom synthesized for this use. This product is highly purified and does not contain any other substances, such as proteins. It has been fluorinated to increase its resistance to degradation by enzymes. Glycosylation and click modification have also been performed on the H-BSA-15 atom spacer.</p>

<p>(S)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a synthetic compound that is used as an impurity standard for HPLC. It is also used in drug development and research and development of pharmaceuticals. This product was made through custom synthesis and is not natural.</p>

<p>Neu5Acα(2-6)Galβ(1-4)GlcNAc-β-ethylamine is a glycosylation agent that is used to modify complex carbohydrates, such as polysaccharides and oligosaccharides. This product is a custom synthesis, which may be modified according to customer specifications. These modifications include methylation, click modification, fluorination, and saccharide modification. The desired purity of this product can be determined by the level of fluorescence in the solution.</p>

<p>1,4-glucotetradecaose derived from starch by hydrolysis and chromatography</p>

<p>Glycyl-lacto-N-fucopentaose II is a synthetic glycosylation product. It has high purity and is easy to use in the synthesis of complex carbohydrates. This product can be fluorinated, methylated, or modified with click chemistry to generate a wide range of products. Glycyl-lacto-N-fucopentaose II is CAS No. 107834-53-2 and has a molecular weight of 707.5 Da.END&gt;&gt;</p>

<p>2'-Fucosyllactose-BSA is a high purity, custom synthesis, synthetic oligosaccharide. It is a glycosylated and methylated monosaccharide that can be used for Click modification with azido-functionalized molecules. 2'-Fucosyllactose-BSA has a CAS number of 113959-06-8 and an Oligosaccharide content of &gt;95%. It is soluble in water and has a Glycosylation content of &gt;95% and a Carbohydrate content of &gt;95%.</p>

<p>6'-Sialyllactose-PAA-biotin is a high purity, custom synthesis, and synthetic oligosaccharide with a molecular weight of 792.04 Da. It is a glycosylated saccharide that has been modified with fluorination, glycosylation, methylation and click modification.</p>

<p>k-carrageenan derived heptasaccharide tetrasulfate+(3-6 anhydrogalactose)</p>

<p>Heparin derived dp24 saccharide ammonium salt is a complex carbohydrate and a saccharide. It is used for the modification of polysaccharides and oligosaccharides. The compound has been shown to reduce blood coagulation by preventing the binding of calcium ions to thrombin, which then blocks the conversion of fibrinogen to fibrin. Heparin derived dp24 saccharide ammonium salt has high purity and can be custom synthesized with high quality. The compound is also methylated, glycosylated, or click-modified.</p>

<p>6'-Sialyllactosyl azide is a modified carbohydrate that can be synthesized from sialic acid and azide. The synthesis of 6'-sialyllactosyl azide is a modification of the glycosylation reaction. It is a monosaccharide, methylated at the hydroxyl group, and has one glycosylation site with a glycose molecule attached to it. This product has high purity and CAS number. It is also synthesized using synthetic methods and has a molecular weight of 232.6 g/mol.</p>

<p>3'-Sialyllactose-GEL is a custom synthesis of a complex carbohydrate. It has CAS No. and is a polysaccharide that has been modified by methylation, glycosylation, and click modification. 3'-Sialyllactose-GEL is a high purity product with fluorination. It is synthetic and has a molecular weight of 1,000 Daltons.</p>

<p>N-Acetyl-D-lactosamine BSA (3 atom spacer) is a synthetic oligosaccharide with 3 acetyl groups on the reducing end and a biotin-streptavidin complex attached to the nonreducing end. It is used for Methylation, saccharide, Polysaccharide, Click modification, CAS No. 174866-48-9, Modification, Oligosaccharide, Custom synthesis, Glycosylation, High purity, Carbohydrate, sugar, Synthetic, Fluorination and complex carbohydrate research.</p>

<p>This is a custom-synthesized oligosaccharide that was modified to include a spacer and biotin. It has been synthesized by methylation and click modification, which are chemical reactions that produce monomeric units with high purity. The oligosaccharide was then fluorinated to give it a desired property. The oligosaccharide is composed of three sugar units: glucose, galactose, and mannose. This product is intended for use in research purposes only.</p>

<p>Reductive amination of memantine with disaccharide.</p>

<p>Desthiobiotin is a modified form of biotin that binds less tightly to biomolecules like proteins and carbohydrates than it does biotin, while still providing excellent specificity in affinity purification methods (Hirsch, 2002). The structure of GD2-oligosaccharide-desthiobiotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). The desthiobiotin is attached β to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentration on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>3'-Sialyl Lewis X-BSA is a custom synthesis that is a complex carbohydrate. This product has CAS number and is polysaccharide modification with methylation, glycosylation, and click modification. The 3'-Sialyl Lewis X-BSA is fluorinated for high purity and synthetic.</p>

<p>4-Methoxyphenyl 2,3,6-tri-O-benzyl-4-O-(2,3-di-O-benzyl-b-D-galactopyranosyl)-b-D-glucopyranoside is a synthetic carbohydrate. It is made up of a saccharide and a sugar. This chemical has been fluorinated with the use of hydrogen fluoride gas. The chemical also has methyl groups that have been added to it. The chemical is highly pure and was custom synthesized for this project. This chemical can be used in glycosylation or click chemistry.</p>

<p>Blood group antigen derivative with spacer arm</p>

<p>The linker N-Allyloxycarbonyl-b-lactosamine (NALB) is a bifunctional molecule that can be used to form triplexes with DNA. The NALB has been shown to inhibit the growth of gram-negative bacteria such as Escherichia coli and Haemophilus influenzae by binding to the bacterial cell wall and disrupting its permeability. The linker is synthesized by solid phase synthesis. This process involves the stepwise addition of building blocks in a sequence that is predetermined. The residues are usually protected with protecting groups, which are then removed at the end of the synthesis process.</p>

<p>k-carrageenan derived pentasaccharide trisulphate+(3-6 anhydrogalactose)</p>

<p>3-O-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranosyl)-1,2-di-O-benzyl-4,6-O-benzylidene--D--mannopyranoside is an oligosaccharide that has a high purity and custom synthesis. This compound is synthesized by Click modification of the sugar with fluorination. The glycosylation and methylation reactions are then carried out to obtain the final product. 3--0-(2--Acetamido--3,4,6--tri--O--acetyl--2--deoxy---D----glucopyranosyl)--1,2--di--O-----benzyl----4,6---O------benzylidene----D--------mannopyranoside is used in the synthesis of oligosaccharides for</p>

<p>3-(Hepta-O-acetyl-b-lactopyranosyl)thio-propanoic acid is a synthetic glycosylate that has been subjected to a click reaction with 4-iodo-1,1,3,3,-tetramethyluronium tetrafluoroborate. This glycoside has a purity of &gt;98% and is offered at a price of $6.00/g.</p>

<p>Dimeric Lewis X hexasaccharide-APE-HSA is a carbohydrate molecule that is a modification of a saccharide. It is an oligosaccharide sugar with a CAS number. The monosaccharide sugar in this molecule has been synthetically modified and fluorinated to yield the desired product. This complex carbohydrate has been custom synthesized for high purity and has undergone methylation and glycosylation reactions to achieve the desired modification. The final result of these modifications is a dimeric Lewis X hexasaccharide-APE-HSA, which will be used as an immunogen.</p>

<p>The chemical compound 2-Acetamido-1,6-di-O-benzyl-3-O-(2,3,4-tri-O-benzyl-aL-fucopyranosyl)-4-O-[2-O-(2,3,4 -tri-O benzyl aL fucopyranosyl) 3,4,6 tri O benzyl bD galactopyranosyl]-2 deoxy D glucopyranoside has the CAS number 6092097. This is a synthetic monosaccharide that is not found in nature. It is an oligosaccharide and complex carbohydrate with glycosylation and polysaccharide modifications. The high purity of this compound makes it an excellent choice for use in research or as a precursor for other compounds.</p>

<p>Methylated, saccharide-containing, polysaccharide-containing, carbohydrate-containing. CAS No.: 169800-74-1. Click modification: Click chemistry reaction with a reactive group on the saccharide or polysaccharide to form a bond with another molecule. Modification: The addition of one or more side chains to a saccharide or polysaccharide to produce a modified carbohydrate. Oligosaccharides: Carbohydrates that are composed of only two to ten monosaccharides. Glycosylation: The process in which a glycosyl group is transferred from an activated donor sugar to an acceptor molecule, forming glycosidic linkage (e.g., between sugars). High purity: The degree of chemical purity as expressed by the percent of impurities that may be present in the product (e.g., 99% pure). Carbohydrate: A class of organic compounds that includes sugars and starches and functions</p>

<p>Blood group B antigen trisaccharide conjugated to Biotin</p>

<p>3,2'-Di-O-acetyl-3',4'-O-carbonyl-6,6'-di-O-tert-butyldimethylsilyl-lactal is a fluorinated oligosaccharide that is custom synthesized for glycosylation and polysaccharide modifications. This product has been shown to be resistant to degradation by enzymes, including aminoglycosides, beta-lactam antibiotics, and penicillin. 3,2'-Di-O-acetyl-3',4'-O-carbonyl-6,6'-di-O-tert-butyldimethylsilyl--lactal is a high purity product with CAS number 207787 - 39 - 0.</p>

<p>Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is a modification of the carbohydrate, which is a complex carbohydrate. It has been synthesized using Custom synthesis and Oligosaccharide. This product is highly pure, with a purity of 99%. Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-Dpglucopyranoside is used in the synthesis of Monosaccharide and Methylation. It can also be used in Glycosylation and Polysaccharide as well as for sugar or Fluorination.</p>

<p>NGA4 N-glycan is a monosaccharide that is methylated and glycosylated to form an oligosaccharide. It has a molecular weight of 1205 g/mol. This product can be used in the production of glycoconjugates, which are used in the treatment of cancer and inflammatory diseases.</p>

<p>Fully acetylated cellohexoses, parts of a polymer homologous series of oligosaccharides isolated from cellulose by acetolysis followed by chromatography.</p>

<p>3,4-Di-O-acetyl-2,6-di-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-a-D-mannopyranosyl trichloroacetimidate is a modified sugar with the molecular formula of C54H79F14N5O26. It is a complex carbohydrate that can be synthesized and custom made. It has high purity and CAS No., and can be methylated, glycosylated, or polysaccarided. This product can also be fluorinated to produce a saccharide with the molecular formula of C54H79F14N5O26F3.</p>

<p>GM3-ganglioside NBD (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked α2,3 to the galactose residue with nitrobenzoxadiazole (NBD) linked β to position 1 on the reducing terminal glucose residue, in place of the ceramide fatty acid (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain, and melanomas, where it is frequently found to be overexpressed. GM3 ganglioside is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganglioside is implicated in various other diseases involving chronic inflammation, such as: insulin resistance, leptin resistance, T-cell function, and immune disorders (e.g. allergic asthma). It has also been shown to play an essential role in murine and human auditory systems, and is a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).</p>

<p>Benzyl 3-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-4,6-O-benzylidene-D-galactopyranose is an oligosaccharide with a complex carbohydrate structure. It is a synthetic sugar that has been modified by fluorination and monosaccharide modifications. The product has a CAS No. of 155835-96-4 and can be custom synthesized to meet specific requirements. It is available in high purity and can be used in glycosylation reactions or click chemistry modifications.</p>

<p>Calcipotriol monohydrate, a Vitamin D3 analog, binds well to the vitamin D receptor, used in psoriasis research.</p>

<p>Methyl 2-acetamido-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-a-D-galactopyranoside is a modified saccharide with a fluorinated methyl group. It is used as an intermediate for the synthesis of oligosaccharides and complex carbohydrates.</p>

<p>4-Methoxyphenyl 3-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosylonate)-2,6 -di--Obenzyl b--D--galactopyranoside is a synthetic carbohydrate. This compound has been custom synthesized for research purposes. The chemical structure of this compound is a methylated oligosaccharide with the following modifications: click modification and fluorination.</p>

<p>Hyaluronate fluorescein is a synthetic, high purity complex carbohydrate with a molecular weight of 1500kDa. It is a modification of the naturally occurring polysaccharide hyaluronan. It is composed of repeating units of the monosaccharide D-glucuronic acid and the disaccharide N-acetyl-D-glucosamine. Hyaluronate fluorescein is synthesized by methylation and glycosylation of D-glucuronic acid, followed by fluorination to produce the fluorinated saccharide hexafluoro-D-glucuronic acid, which reacts with N-acetyl-D-glucosamine in an amidation reaction. The product can then be modified to produce hyaluronate fluorescein.</p>

<p>The maltose solution we offer is a 20% solution in water and of high purity and can be customized to meet your needs.</p>

<p>Hyaluronate rhodamine is a modified, fluorinated, methylated, and monosaccharide-containing polysaccharide. It is synthesized by the addition of a click modification to an oligosaccharide. The saccharide is used in glycosylation reactions to produce complex carbohydrates. Hyaluronate rhodamine has a molecular weight of 2500kDa.</p>

<p>3,4,6-Tri-O-acetyl-2-O-(2,3,4-tri-O-benzoyl-a-L-fucopyranosyl)-D-galactopyranose (TFP) is a fluorinated carbohydrate synthesized by the reaction of 3,4,6 trihydroxyacetophenone with 2,3,4 trihydroxypentanediol and acetyl chloride. TFP is a complex carbohydrate that can be used to modify proteins and glycoproteins. The methylation of TFP has been shown to decrease the binding affinity between lectins and glycoproteins.</p>

<p>Gentiobiulose is a natural sweetener that is made from the sugar glucose and has a low glycemic index. It is produced by the enzymatic reaction of glucose with an acid catalyst in the presence of c1-6 alkyl groups. Gentiobiulose has a diameter of 0.5-2 micrometers and is used as a prebiotic, which promotes the growth and activity of beneficial bacteria in the gut. In addition, gentiobiulose can be used as an ingredient for detergent compositions because it has a high viscosity and particle size.</p>

<p>Hyaluronate fluorescein is a polymer of hyaluronic acid that has been modified with fluorescein. It is synthesized by the methylation and saccharide coupling of an oligosaccharide, followed by Click modification and the addition of a fluorescent dye. Hyaluronate fluorescein has a molecular weight of 2500kDa. It is highly purified and can be custom-synthesized to suit specific needs.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. A number of publications have suggested that agaroheptaose has properties that include: anti-microbial, antiviral, prebiotic, anti-tumoral, immunomodulatory, anti-inflammatory, glucosidase inhibitory, and hepatoprotective properties.</p>

<p>3-O-(2-Acetamido-2-deoxy-D-glucopyranosyl)-1,2-di-O-benzyl-4,6-O-benzylidene-D-mannopyranoside is a synthetic sugar that is used in the synthesis of glycosylations. It has been fluorinated and methylated to increase its stability and reactivity. It is also synthetically derived from a saccharide and modified for use in Click chemistry. 3-O-(2-Acetamido-2-deoxy--D--glucopyranosyl)-1,2--di--O--benzyl--4,6--O--benzylidene--D--mannopyranoside is soluble in water and ethanol. This product has CAS No. 5118876–78–3 and can be custom synthesized by us.</p>

<p>Tumor associated antigen and target for the development of anti-cancer vaccines.</p>

<p>3-O-Acetyl-1,6-anhydro-2-azido-2',3'-di-O-benzyl-4',6'-O-benzylidene-2-deoxy-b,D cellobiose is a fluorinated oligosaccharide that can be customized for a variety of applications. The sugar unit contains an acetyl group on the C1 position and an azido group at the C2 position. This compound has been subjected to click chemistry in order to form a covalent bond with 4,6'-O-benzylidene 2,3'-dideoxy b,D cellobiose.</p>

<p>Gala1-2Gal-HSA is a modified, complex carbohydrate. The carbohydrate is synthesized by methylating, glycosylating and polysaccharide synthesis to produce Gala1-2Gal-HSA. It has CAS No. and can be custom synthesized with high purity. Gala1-2Gal-HSA is a monosaccharide that can be fluorinated or saccharide that can be glycosylated or methylated. Gala1-2Gal-HSA has many applications in the biomedical field such as inhibiting inflammation and preventing cancer metastasis.</p>

<p>ABO trisaccharide conjugated to BSA via Biotin &amp; an aminophenyl ethyl spacer</p>

<p>A1 N-glycan is a custom synthesis, complex carbohydrate that is an oligosaccharide and polysaccharide. It is modified with saccharides, methylation, glycosylation, and fluorination. A1 N-Glycan has high purity and is custom synthesized to order.</p>

<p>Hyaluronate biotin is a high purity and complex carbohydrate. It is synthesized by methylation, saccharide, polysaccharide, and glycosylation of natural hyaluronic acid. Hyaluronate biotin is a modified form of hyaluronic acid that contains an additional biotin molecule per every 500 kDa of molecular weight. This modification can be used in the development of new drugs or as a supplement to improve joint health.</p>

<p>N-acetyllactosamine is a monosaccharide that belongs to the group of n-acetyllactosamine. It can be found in the form of an agglutinin, lactose, and lectin. The conformation of this molecule is an equilibrium between its alpha and beta forms. The pyridine can act as an acid catalyst for the alpha conformation. There are two forms of this molecule: one synthesized from D-glucose and one synthesized from D-galactose. 1,6-Anhydro-4-O-b-D-galactopyranosyl-b-D-glucopyranose is synthesized from D-glucose. Oligosaccharides containing this molecule have been expressed in Saccharomyces cerevisiae cells and purified by affinity chromatography on columns that contain immobilized antibody to human serum albumin. This molecule has been shown</p>

<p>Gala1-3Galb1-3GlcNac</p>

<p>This is a synthetic sugar that can be used for glycosylation, oligosaccharides, and saccharides. It has been modified with fluorination, methylation, and click chemistry. This product is available in custom synthesis upon request.</p>

<p>Drug carrier for cancer therapy &amp; imaging, biocompatible, soluble, biodegradable</p>

<p>Tetrasaccharide dp4 is a custom synthesis that is modified with fluorination, methylation, and click modification of the monosaccharides. It can be used for the synthesis of oligosaccharides and saccharides. Tetrasaccharide dp4 is a glycosylated carbohydrate that belongs to the group of polysaccharides. This product has CAS number 87392-00-6.</p>

<p>The 6-deoxy-6-fluorocyclomaltoheptaose is a low molecular weight compound that has been found to have anti-amylase activity. This substance is characterized by its chromatographic techniques, which can be used to identify the chemical structure of the molecule. The 6-deoxy-6-fluorocyclomaltoheptaose has been found to consist of an amylase inhibitor and an enzyme substrate. It exhibits specificity for the catalytic site of amylase, which is located in subsite 1, and it attacks this substrate at the 6-position of glucose. This substance is not as potent as other amylase inhibitors such as d-glucose, but it does show greater specificity for amylase than other substances with similar structures.</p>

<p>3'-Sialyl-N-acetyllactosamine-BSA is an oligosaccharide that is a component of the glycosylation pathway. It is synthesized from 3'-sialyllactose and N-acetylglucosamine. This compound can be modified with fluorine, methylation, or click chemistry to yield novel derivatives for use in research.</p>

<p>1-D-a-Galactopyranosyl-4-O-[1-(2-octadecylthioethyl)-(b-D-galactopyranoside)] is a complex carbohydrate that contains a fluorinated sugar. It is synthesized from a monosaccharide and an oligosaccharide and glycosylated with a polysaccharide. The compound has been modified to include methylation and click modification. 1-D-a-Galactopyranosyl-4-O-[1-(2-octadecylthioethyl)-(b-D-galactopyranoside)] can be purchased in high purity from the CAS registry number of 538570–75–6.</p>

<p>a1,6-Mannobiose-BSA is a fluorinated monosaccharide that has been synthesized from mannose. It is a synthetic oligosaccharide that is used in glycosylation and polysaccharide modification. The compound has been modified with methyl groups and has undergone click chemistry to produce a reactive site on the sugar ring. This product has been synthesized using high purity reagents and has CAS No. 73978-99-2.</p>

<p>Globo series antigen</p>

<p>Methyl 4-O-[4,6-O-benzylidene)-b-D-galactopyranosyl] b-D-glucopyranoside is a synthetic sugar with a high purity and custom synthesis. It has been modified by fluorination, methylation, glycosylation, and click modification. This product can be used as a pharmaceutical ingredient for the treatment of tuberculosis.</p>

<p>3-O-b-D-Galactosylsucrose is a synthetic, fluorinated, high purity, oligosaccharide. It is a complex carbohydrate that contains an O-linked glycosylated monosaccharide. This product has been modified with a click modification. The CAS number for this product is 686717-73-7 and it can be synthesized to order.</p>

<p>Heparin disaccharide II-H disodium salt is a complex carbohydrate with the chemical formula C3H6Na2O14. It has a molecular weight of 617.8 and a melting point of 204.5°C. The compound has been modified by methylation, glycosylation, fluorination, and click modification. It is a synthetic oligosaccharide with high purity and custom synthesis.</p>

<p>Benzyl 2-acetamido-4-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-b-D-galactopyranoside is a synthetic glycoside that has been modified with fluorination. It is an oligosaccharide sugar that has been synthesized from the monosaccharide galactose and the disaccharide maltose. The chemical formula for this compound is C14H22FNO6. This product can be used in custom synthesis or as a research reagent.</p>

<p>Man-7D1 N-glycan is a synthetic, fluorinated, monosaccharide oligosaccharide that is custom synthesized for glycosylation. It has been shown to be an effective substrate for glycosylation and can be used in the synthesis of complex carbohydrates. The modification of Man-7D1 N-glycan includes fluorination, methylation, and click chemistry. This product is available in high purity and with a CAS number 83178-05-6.</p>

<p>3-O-(2,3,4,6-Tetra-O-benzyl-a-D-glucopyranosyl)-1,2,4,6-tetra-O-acetyl-b-D-glucopyranose is an oligosaccharide that has been modified with a click modification. This compound is a complex carbohydrate and it is synthesized from a monosaccharide. 3-O-(2,3,4,6-Tetra-O-benzyl-a-D--glucopyranosyl)-1,2,4,6-- tetra--O--acetyl--b--D--glucopyranose is used in methylation reactions.</p>

<p>Methyl 3-O-(b-D-galactopyranosyl)-b-D-galactopyranoside is a disaccharide that is the residue of 6-fluoro-3-indoxyl beta-D-galactopyranoside. This product is a glycoside of methyl 3,6,3',6'-tetraacetate and b-D-galactose.</p>

<p>Decasaccharide dp10 is a complex carbohydrate that is made up of ten monosaccharides. It is a synthetic oligosaccharide that has been fluorinated and glycosylated. The decasaccharide has been synthesized using click chemistry and methylation, before being purified to produce a high-purity product. Decasaccharide dp10 can be used in the modification of complex carbohydrates, as well as for the synthesis of glycans with customized structures.</p>