
Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10354 products of "Benzimidazole and Imidazole Derivatives"
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2-cyclopropyl-1H-1,3-benzodiazole-5-carboxylic acid hydrochloride
CAS:Purity:95.0%Molecular weight:238.66999816894537-CHLORO-5-METHYL-2-(2-(1-METHYL-1H-BENZO[D]IMIDAZOL-2-YL)ETHYL)-2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDINE-1,6(5H)-DIONE
CAS:Purity:95.0%Molecular weight:356.80999755859375Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
CAS:Purity:95.0%Molecular weight:367.3999938964844Temazepam b-D-Glucuronide, Mixture of Diastereomers
CAS:Controlled Product<p>Applications A glucuronide metabolite of Diazepam.Controlled substance (depressant). Sedative, hypnotic.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Formula:C22H21ClN2O8Color and Shape:Off-WhiteMolecular weight:476.862-(4-Chlorobenzyl)-1H-benzimidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:242.71000671386724-bromo-2-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol
CAS:Purity:95.0%Molecular weight:360.25500488281252-(4-Bromo-phenyl)-1-methyl-1H-benzoimidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:287.16000366210947-Bromo-6-methyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazole
CAS:Purity:95.0%Molecular weight:341.3240051269531N-(2-CHLORO-5-METHOXYPYRIMIDIN-4-YL)-1H-INDAZOL-6-AMINE
CAS:Purity:95.0%Molecular weight:275.700012207031253-Methyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazole-5-carboxylic acid
CAS:Purity:97%Molecular weight:192.17399597167972-(Pyridin-3-yl)-1H-benzo[d]imidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:195.22500610351562{5-[1-(benzylamino)cyclohexyl]-1H-tetrazol-1-yl}acetic acid
CAS:Purity:95.0%Molecular weight:315.377014160156251'-Hydroxy Midazolam-β-D-glucuronide
CAS:Controlled Product<p>Applications The major metabolite of Midazolam (M343000(P)). Midazolam is an anesthetic; anticonvulsant; sedative; hypnotic. It is a positive allosteric modulator of the GABAA receptor.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C24H21ClFN3O7Color and Shape:White To Off-WhiteMolecular weight:517.892,3-Diphenyl-5-(thiophen-2-yl)-2H-tetrazol-3-ium chloride
CAS:Purity:98%Molecular weight:340.82998657226561-Isopropyl-6-(6-(4-isopropylpiperazin-1-yl)pyridin-3-yl)-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-1H-indazole-4-carboxamide
CAS:Purity:98%Color and Shape:SolidMolecular weight:569.754028320313Rivastigmine Tartrate Salt
CAS:Controlled ProductFormula:C14H22N2O2·C4H6O6Color and Shape:White To Off-WhiteMolecular weight:400.421-Cyclopropyl-1H-benzo[d]imidazol-2(3H)-one
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:174.20300292968751-(TETRAHYDRO-2H-PYRAN-2-YL)-1H-INDAZOLE-6-CARBOXYLIC ACID
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:246.26600646972656Tert-butyl(4s)-4-[(E)-3-bromoprop-1-enyl]-2,2-dimethyl-oxazolidine-3-carboxylate
CAS:Purity:97% mix TBC as stabilizerMolecular weight:320.22698974609375Ethyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
CAS:Purity:97.0%Molecular weight:468.1909886283-Hydroxy-N-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-naphthamide
CAS:Purity:95.0%Molecular weight:319.320007324218754-Hydroxy Omeprazole Preparation Kit
CAS:Controlled ProductFormula:C16H17N3O3SColor and Shape:Off White SolidMolecular weight:331.395-Bromo-4-methoxy-1H-indazole
CAS:Formula:C8H7BrN2OPurity:98%Color and Shape:SolidMolecular weight:227.0612-[(Tetrahydro-1,1-dioxido-3-thienyl)methyl]-1H-benzimidazole
CAS:Purity:97%Molecular weight:250.320007324218751-(2-naphthylmethyl)-1H-benzimidazole-2-carbaldehyde
CAS:Purity:95.0%Molecular weight:286.3340148925781(2-Chlorophenyl)diphenylmethanol
CAS:<p>Impurity Clotrimazole EP Impurity A<br>Applications (2-Chlorophenyl)diphenylmethane (Clotrimazole EP Impurity A) is a triarylmethane with antiproliferative activity. (2-Chlorophenyl)diphenylmethane is a degradation product of the antifungal agent Clotrimazole (C587400). Clotrimazole Related Compound A<br>References Suzuki, M. Iyak. Kenk., 23, 44 (1992); Hajkova, R. et al.: Talanta, 73, 483 (2007); Sabourin, L. et al.: Environ. Toxicol. Chem., 30, 582 (2011);<br></p>Formula:C19H15ClOColor and Shape:NeatMolecular weight:294.77(S)-N-Desethyl Oxybutynin Hydrochloride
CAS:Controlled Product<p>Applications (S)-Metabolite of the drug Oxybutynin. Used in the treatmentment of incontinence.<br>References Ehlert, F., et al.: Life Sci., 74, 355 (2003), Matsui-Sakata, A., et al.: Drug Metab. Pharmacokinet., 20, 187 (2005), Hegde, S., et al.: Br. J. Pharmacol., 147, S80 (2006), Tashiro, M., et al.: Br. J. Clin. Pharmacol., 61, 16 (2006),<br></p>Formula:C20H27NO3·ClHColor and Shape:NeatMolecular weight:365.89Scopine Di(2-thienylglycolate)
CAS:<p>Impurity Tiotropium EP Impurity B<br>Applications Scopine Di(2-thienylglycolate) (Tiotropium EP Impurity B) is a precursor to Tiotropium Bromide.<br>References Buchwald, P., et al.: Pharmazie., 55, S210 (2000),<br></p>Formula:C18H19NO4S2Color and Shape:NeatMolecular weight:377.48(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
CAS:Purity:95.0%Molecular weight:345.42001342773442-Butyl-3-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[4.4]non-1-en-4-one
CAS:Purity:97.0%Color and Shape:Solid, White - Almost white powderMolecular weight:428.5400085449219N-(3-(1H-imidazol-1-yl)propyl)-7-chloro-4-methoxybenzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:322.80999755859375Modafinil-d10 Carboxylate
CAS:Controlled Product<p>Applications A metabolite of Modafinil, a central nervous system vigilance promoting agent, which possesses neuroprotective properties.<br>References Duteil, J., et al.: Eur. J. Pharmacol., 180, 49 (1990), Wong, Y., et al.: J. Clin. Pharmacol., 317, 30 (1999), Robertson, P., et al.: Drug Disp., 42, 123 (2003)<br></p>Formula:C15H4D10O3SColor and Shape:NeatMolecular weight:284.4Omeprazole-d3
CAS:Controlled Product<p>Applications Labelled Omeprazole, which binds covalently to proton pump, it inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C172H3H16N3O3SColor and Shape:NeatMolecular weight:348.432-(2-Cyclopropyl-6-fluoro-1H-1,3-benzodiazol-1-yl)acetic acid
CAS:Molecular weight:234.22999572753906Scopolamine N-Oxide
CAS:<p>Stability Hygroscopic<br>Applications Scopolamine N-Oxide is an impurity of Scopolamine (S200000), an acetylcholine antagonist used in the treatment of motion sickness and also used as antiemetic, antispasmodic, mydriatic, preanesthetic agents.<br>References Shahwar, D., et al.: Turk. J. Chem., 36, 257 (2012); Paula, S., et al.: J. Med. Chem., 47, 133 (2004); Wu, H.L., et al.: J. Chromatograph. A., 802, 107 (1998); Phillipson, J.D., et al.: J. Pharma. Pharmcol., 25, 116 (1973);<br></p>Formula:C17H21NO5Color and Shape:NeatMolecular weight:319.351-Boc-4-Imidazol-2-ylpiperidine
CAS:Formula:C13H21N3O2Purity:98.0%Color and Shape:CrystallineMolecular weight:251.33Metconazole
CAS:<p>Applications Metconazole is a conazole based fungicide used for the control of black sigatoka disease on bananas. Metconazole acts primarily as an inhibitor of ergosterol biosynthesis which interferes with the synthesis of fungal cell membranes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cools, H.J., et al.: Pest. Manage. Sci., 68, 1034 (2012); Nam, M.H., et al.: Res. Plant. Disease., 17, 295 (2011);<br></p>Formula:C17H22ClN3OColor and Shape:White To Off-WhiteMolecular weight:319.83(5-Amino-tetrazol-2-yl)-acetic acid
CAS:Formula:C3H5N5O2Color and Shape:SolidMolecular weight:143.106Miconazole N-(2-Methyl)propanoate
CAS:Controlled Product<p>Applications Miconazole N-(2-Methyl)propanoate is an impurity of Miconazole (M342500). Miconazole EP Impurity E.<br></p>Formula:C22H20Cl4N2O3Color and Shape:NeatMolecular weight:502.221-(4-Fluoro-benzyl)-2-(pyrrolidin-3-ylmethoxy)-1H-benzoimidazole hydrochloride
CAS:Purity:95.0%Molecular weight:361.8500061035156N,N-Diphenyl-1H-imidazole-1-carboxamide
CAS:Purity:97.0%Color and Shape:Solid, No data available.Molecular weight:263.29998779296875Tinidazole-d5
CAS:Controlled Product<p>Applications Labelled Tinidazole. Antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.<br>References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),<br></p>Formula:C8H8D5N3O4SColor and Shape:NeatMolecular weight:252.35-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-2H-benzimidazol-2-one
CAS:<p>Applications 5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-2H-benzimidazol-2-one is a metabolite of Triclabendazole (T774175), the only anthelmintic drug, which is active against immature, mature and adult stages of fluke.<br>References Whelan, M., et al.: J. Chromato., 1275, 41 (2013); Barrera, S., et al.; Antimicrob. Agent. Chemother., 56, 3535 (2012);<br></p>Formula:C13H7Cl3N2O2Color and Shape:Off-White To BrownMolecular weight:329.572-Nitroaniline
CAS:Controlled Product<p>Impurity Albendazole Impurity 4<br>Applications 2-Nitroaniline, is the main precursor to phenylenediamines, which are converted to benzimidazoles, a family of heterocycles that are key components in pharmaceuticals. Albendazole Impurity 4<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Booth, G.,et al.: Ull. Encyc. Indust. Chem. (2007);<br></p>Formula:C6H6N2O2Color and Shape:NeatMolecular weight:138.124-(1H-Benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:201.18899536132812N-Nitroso Dextromethorphan
CAS:Controlled Product<p>Applications N-Nitroso Dextromethorphan is an impurity of Dextromethorphan (D299445). Dextromethorphan is an antitussive compound showing analgesic properties. Used in cough medication formulations.<br>References Church J. et al.: Can J Physiol Pharmacol., 67, 561 (1989); Carliss, R. et al.: Neurotoxicology., 28, 813 (2007);<br></p>Formula:C17H22N2O2Color and Shape:Light YellowMolecular weight:286.369N-Nitroso Imidapril
Controlled ProductFormula:C20H26N4O7Color and Shape:Off-WhiteMolecular weight:434.443Hydroxy Voriconazole
Controlled Product<p>Applications A hydroxylated derivative of Voriconazole (V760000), a systemic antifungal and ergosterol biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997).<br></p>Formula:C16H14F3N5O2Color and Shape:NeatMolecular weight:365.315-(1-Biphenyl-4-yl-1H-tetrazol-5-yl)-4-methyl-pyrimidin-2-ylamine
CAS:Color and Shape:SolidMolecular weight:329.36700439453125Nimorazole
CAS:Controlled Product<p>Applications Nimorazole is an antimicrobial with activity against anaerobic bacteria and protozoa.<br>References Ratnaparkhi, M.P., et al.: Res. J. Pharma. BIol. Chem. Sci., 3, 303 (2012); Toustrup, K., et al.: Radiotherap. Oncol., 102, 122 (2012);<br></p>Formula:C9H14N4O3Color and Shape:NeatMolecular weight:226.23rel-(R,R)-Voriconazole
CAS:Controlled Product<p>Applications The (R,R)-enantiomer of Voriconazole. An antifungal (systemic). An ergosterol biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997),<br></p>Formula:C16H14F3N5OColor and Shape:NeatMolecular weight:349.31Omeprazole sulfide N-Oxide
CAS:<p>Applications 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole N-Oxide is a metabolite of Omeprazole (O635000), an proton inhibitor used as an antiulcerative agent.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O3SColor and Shape:Off-WhiteMolecular weight:345.42Lamotrigine N-Acetate
CAS:Controlled Product<p>Applications Lamotrigine N-Acetate is a derivative of the anticonvulsant Lamotrigine (L173250).<br></p>Formula:C11H9Cl2N5OColor and Shape:NeatMolecular weight:298.13Miconazole Impurity H
CAS:Controlled Product<p>Impurity Miconazole EP Impurity H<br>Applications Miconazole Impurity H (Miconazole EP Impurity H), is the impurity of Miconazole (M342500), which is an imidazole antifungal agent, that is applied topically to the skin or to mucus membranes for the treatment of fungal infections.<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H16Cl2N2OColor and Shape:NeatMolecular weight:347.245-Methyl-2-phenoxypyridine
CAS:Controlled ProductFormula:C12H11NOColor and Shape:NeatMolecular weight:185.232-Methyl-5-nitro-1-(2-oxiranylmethyl)-1H-imidazole
CAS:Controlled Product<p>Applications 2-Methyl-5-nitro-1-(2-oxiranylmethyl)-1H-imidazole is an impurity of Ornidazole (O688500) which has antifertility activity.<br>References Jones, A., et al.: Xenobiotica, 27, 711 (1997); Cooper, T., et al.: J. Andrology, 18, 431 (1997)<br></p>Formula:C7H9N3O3Color and Shape:NeatMolecular weight:183.16rac Dihydro Mebendazole
CAS:<p>Applications The reduced metabolite of Mebendazole (M200500).<br>References Facino, R., et al.: Biol. Mass Spectrom, 21, 195 (1992), Iosifidou, E., et al.: Drug Metab. Dispos., 25, 317 (1997), De Ruyck, H., et al.: J. Agric. Food Chem., 49, 610 ( 2001),<br></p>Formula:C16H15N3O3Color and Shape:Light YellowMolecular weight:297.31Apoatropine Hydrochloride
CAS:<p>Applications Apoatropine is an alkaloid derivative with the potential to be an antibacterial.<br>References Cherkaoui, S. et al.: Electrophor., 19, 2900 (1998); Marrero-Ponce, Y. et al.: Bioorg. Med. Chem., 13, 2881 (2005);<br></p>Formula:C17H21NO2·ClHColor and Shape:White To Off-WhiteMolecular weight:307.82Des [3-(1-Dimethylamino)ethyl] 3-Acetyl Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity C; USP Related Compound D<br>Applications Des [3-(1-dimethylamino)ethyl] 3-acetyl Rivastigmine (Rivastigmine EP Impurity C) is a derivative of Rivastigmine (Tartrate: R541000), and acetylcholinesterase inhibitor that is commonly used to treat dementia associated with Parkinson’s disease and Alzheimer’s disease.<br>References Emre, M., et al.: New. Engl. J. Med., 351, 2509 (2004); Polinsky, R.: Clin. Ther., 20, 634 (1998); Wilkinson, D., et al.: Int. J. Clin. Pract., 56, 441 (2001)<br></p>Formula:C12H15NO3Color and Shape:Off-WhiteMolecular weight:221.252-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
CAS:Controlled Product<p>Applications 2-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole is a drug impurity of Lansoprazole, which is a proton pump inhibitor and used to treat stomach and intestinal ulcers.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000); Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001); Barradell, L.B., et al.: Drugs, 44, 225 (1992); Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002); Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006)<br></p>Formula:C14H12N4O3SColor and Shape:NeatMolecular weight:316.344-Nitro-1H-imidazole-1-ethanol
CAS:Controlled Product<p>Applications 4-Nitro-1H-imidazole-1-ethanol<br></p>Formula:C5H7N3O3Color and Shape:WhiteMolecular weight:157.13Methyl ((S)-4-Methyl-2-[2-oxo-2-[[(S)-1-phenylethyl]amino]ethyl]pentyl]carbamate
CAS:Controlled ProductFormula:C18H28N2O3Color and Shape:NeatMolecular weight:320.431,2-Dimethylimidazole-4-sulfonyl chloride
CAS:Formula:C5H7ClN2O2SPurity:95%Color and Shape:SolidMolecular weight:194.63Miconazole Impurity B
CAS:Controlled Product<p>Applications Miconazole Impurity B, is the impurity of Miconazole (M342500), which is an imidazole antifungal agent, that is applied topically to the skin or to mucus membranes for the treatment of fungal infections.<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H15Cl3N2OColor and Shape:NeatMolecular weight:381.685-(4-chlorophenyl)-1-(2-methoxyphenyl)-2,3-dihydro-1H-imidazole-2-thione
Molecular weight:316.799987792968756-Bromo-1-cyclopropyl-1,3-dihydro-2H-benzo[d]imidazol-2-one
CAS:Purity:97%Molecular weight:253.09899902343755-O-Desmethyl Donepezil-d5
CAS:Controlled ProductFormula:C23H22D5NO3Color and Shape:White To Off-WhiteMolecular weight:370.5Hydroxy Itraconazole-d8
CAS:Controlled Product<p>Applications An isotopically Labelled metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. It is a COVID19-related research product.<br>References Saag, M., et al.: Antimicrob. Agents Chemother., 32, 1 (1988), Haria, M., et al.: Drugs, 51, 585 (1996), Kousoulos, C., et al.: Anal. Bioanal. Chem., 384,199 (2006),<br></p>Formula:C35D8H30Cl2N8O5Color and Shape:NeatMolecular weight:729.683-(1 H -Benzoimidazol-2-yl)-4-chloro-phenylamine
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:243.69000244140625Tert-Butyl 4-(3-iodo-1H-indazol-6-yl)piperazine-1-carboxylate
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:428.273986816406253-(1H-IMIDAZOL-2-YL)PROPANOIC ACID HCL
CAS:Formula:C6H9ClN2O2Purity:97%Color and Shape:SolidMolecular weight:176.62'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carbaldehyde
CAS:Purity:98%Molecular weight:250.26100158691406N-Desalkyl Itraconazole
CAS:Controlled Product<p>Applications N-Desalkyl Itraconazole is a derivative of itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C31H30Cl2N8O4Color and Shape:NeatMolecular weight:649.53

