Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10345 products of "Benzimidazole and Imidazole Derivatives"
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Di-2-thienylmethanone
CAS:<p>Di-2-thienylmethanone is a pyrazole with an activation energy of about 10.5 kcal/mol. It has been found to be toxic and can cause cell lysis. This molecule has been used in the synthesis of a number of drugs, including thiopental, a barbiturate that is used as an anaesthetic. Di-2-thienylmethanone is also the precursor for the synthesis of fluoroquinolones, which are potent antibacterial agents. The Friedel-Crafts reaction is one way this molecule is synthesized, and it involves the addition of an alkyl halide to an unsaturated double bond. This reaction is named after Charles Friedel and James Crafts who first discovered it in 1877.</p>Formula:C9H6OS2Purity:Min. 95%Color and Shape:White PowderMolecular weight:194.28 g/mol5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one (donepezil impurity)
CAS:<p>5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one (donepezil impurity) is an analytical standard used as a reference in HPLC assays for donepezil. It is also a metabolite of donepezil and has been found to have pharmacological activity similar to that of the parent compound. This impurity is present in donepezil drug products at levels up to 0.5%.</p>Formula:C17H21NO3Purity:Min. 95%Molecular weight:287.35 g/molN-(2-Phenethyl)benzamide
CAS:<p>N-(2-Phenethyl)benzamide (NPEB) is a molecule that belongs to the group of reactive molecules. It has been shown to be toxic to gram-positive bacteria, such as Staphylococcus aureus and Bacillus subtilis, but not gram-negative bacteria such as Escherichia coli. NPEB also has been shown to have locomotor activity in animals, which may be due to its ability to inhibit the mitochondrial electron transport chain and inhibit ATP production. NPEB's biological properties are well characterized. FTIR spectroscopy showed that this molecule has an amide functional group and is a small molecule with a molecular weight of 176.4 g/mol. This molecule was also found to be able to bind to mitochondria in animals.</p>Formula:C15H15NOPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:225.29 g/mol2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole
CAS:<p>2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole is a protonated sulfonamide that is used as an analytical method to detect the presence of other drugs in human liver tissue. It has been shown to inhibit the activity of cytochrome P450 3A4 (CYP3A4), one of the enzymes responsible for metabolizing many drugs. Bromoenol lactone and powder diffraction spectrum are two additional analytical methods that can be used to detect 2-[([(4-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole.</p>Formula:C18H21N3O4SPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:375.44 g/mol(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS:<p>(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a drug used to treat depression. It is an antidepressant drug that inhibits the reuptake of serotonin and norepinephrine in the brain by blocking their transport into the nerve cells. The drug acts as a weak inhibitor of monoamine oxidase (MAO). It also has an effect on bladder function. This compound is synthesized from 1-phenyl-2,5-dihydrothiazole by way of a sequence of reactions that includes the formation of an amine salt via reaction with phosphorus pentoxide and chloroacetic acid followed by conversion to the chloride with thionyl chloride.</p>Formula:C15H15NPurity:Min. 95%Color and Shape:White PowderMolecular weight:209.29 g/molAlbendazole sulfoxide
CAS:<p>Albendazole sulfoxide is a sulfoxide of albendazole. The molecular docking analysis of the two molecules showed that the sulfoxide group is located in the same position as the hydroxyl group on albendazole. It has been shown that this replacement of hydroxyl with a sulfoxide group increases the solubility and stability of albendazole, which may be due to hydrogen bonding interactions between these groups. Albendazole sulfoxide has been shown to be an effective treatment for infections caused by parasites such as helminths. However, it should not be used in combination with drugs that are metabolized by cytochrome P450 enzymes because it can inhibit their activity.</p>Formula:C12H15N3O3SPurity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:281.33 g/molDihydroxy diketo atorvastatin impurity
CAS:<p>Dihydroxy diketo atorvastatin impurity is a synthetic impurity that is generated by the metabolism of atorvastatin. This drug product is an analytical standard for the determination of purity, and can also be used to develop high purity drugs.</p>Formula:C26H24FNO5Purity:Min. 95%Molecular weight:449.47 g/molPantoprazole sulphone
CAS:<p>Pantoprazole sulphone is a proton-pump inhibitor that inhibits the production of stomach acid and protects the esophagus from damage. Pantoprazole sulphone has been shown to be effective in treating heart disease patients and reducing their risk of death. It also has biological properties, including modulating the effects of bosentan, which is used to treat pulmonary arterial hypertension. Pantoprazole sulphone has been shown to be chemically stable and stereoselective, which means it binds more strongly to one site than another. Clinical pharmacology studies have found that pantoprazole sulphone has no effect on abomasal motility or gastric emptying time.</p>Formula:C16H15F2N3O5SPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:399.37 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole
CAS:<p>Omeprazole is a drug that belongs to the class of benzimidazole compounds. It is an inhibitor of gastric acid secretion in the stomach, reducing the production of hydrochloric acid and pepsin. Omeprazole has been shown to have greater chemical stability than other proton pump inhibitors (PPIs), with a higher solubility in water and a longer shelf life. Omeprazole also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Omeprazole also exhibits pharmacokinetic properties that are different from other PPIs. Omeprazole is rapidly absorbed following oral administration and has a high bioavailability, which can be attributed to its hydroxyl group. This hydroxyl group allows for esomeprazole (a prodrug) to be formed by hydrolysis in the gut or liver, increasing omeprazole's absorption and bioavailability.</p>Formula:C17H19N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:329.42 g/mol4-Isobutyl-2-pyrrolidinone
CAS:<p>4-Isobutyl-2-pyrrolidinone is a colorless liquid that belongs to the category of phosphites. It has a high boiling point, which makes it suitable for use in organic solvents and as a heat transfer agent. The thermodynamic properties of 4-Isobutyl-2-pyrrolidinone have been evaluated using the protonation theory. It can be protonated at either the nitrogen or the methyl group, and both forms are present in solution. This means that 4-Isobutyl-2-pyrrolidinone is acidic and can react with other compounds to form salts called lactams. There are two isomers of this compound: cis and trans. Both isomers exist in equilibrium; however, the cis isomer predominates at room temperature. The most common impurities of 4-Isobutyl-2-pyrrolidinone are dehydration products formed during synthesis or</p>Formula:C8H15NOPurity:Min. 95%Color and Shape:White PowderMolecular weight:141.21 g/molOmeprazole impurity F and G
CAS:<p>Omeprazole is a proton pump inhibitor that inhibits the H+/K+-ATPase enzyme in gastric parietal cells. Omeprazole impurity F and G are metabolites of omeprazole. Omeprazole impurity F is a metabolite of omeprazole that forms by oxidation of the methylthio group in omeprazole to form a sulfoxide. Omeprazole impurity G is formed by hydrolysis of the methylthio group in omeprazole to form an alcohol. The purity of this product is high and can be custom synthesized based on customer's needs. It is also available as an HPLC standard or as an API impurity for use in metabolism studies.</p>Formula:C16H13N3O2SPurity:Min. 95%Color and Shape:Red PowderMolecular weight:311.36 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide is a cyclic sulfoxide that has shown to be a potent inhibitor of gastric acid secretion. It is an important intermediate in the synthesis of esomeprazole magnesium, a proton pump inhibitor used to treat gastroesophageal reflux disease and other gastrointestinal disorders. 5-Methoxy-2-[(4-methoxy 3,5 dimethyl 2 pyridinyl) methyl] sulphonyl]-1H benzimidazole N oxide is also known as (RS)-N-[4-(4′ methoxyphenyl)-3,5 dimethylpyrazol -2 - ylmethyl] methanesulfonamide. This compound has been shown to have a polymorphic form with two different</p>Formula:C17H19N3O5SPurity:Min. 95%Color and Shape:PowderMolecular weight:377.42 g/mol2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
CAS:<p>2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].</p>Formula:C15H15N3OS2Purity:Min. 95%Molecular weight:317.43 g/mol5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole
CAS:<p>5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole is a natural product. It is an impurity in the drug development process and may be present as an analytical marker for impurities. 5-Methoxy-2-[(3,5-dimethylpyridinium)methyl]sulfinyl]-1Hbenzimidazole is used as a pharmacopoeia standard and can be synthesized on request.</p>Formula:C16H17N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:315.39 g/molVarenicline
CAS:<p>Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.</p>Formula:C13H13N3Purity:99.76%Color and Shape:SolidMolecular weight:211.265-{[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(4-carbamoyl-2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido]methyl}-2-methoxybenzoic acid
CAS:Purity:98%Molecular weight:669.77899171-Methyl-1H-indazole-6-boronic acid
CAS:Formula:C8H9BN2O2Purity:95%Color and Shape:SolidMolecular weight:175.983-Iodo-6-(trifluoromethyl)-1H-indazole
CAS:Formula:C8H4F3IN2Purity:98%Color and Shape:SolidMolecular weight:312.034Methyl 5-oxazolecarboxylate
CAS:Formula:C5H5NO3Purity:98%Color and Shape:No data available.Molecular weight:127.0991-(4-Chlorophenyl)-1H-imidazole-4-carboxylic acid
CAS:Formula:C10H7ClN2O2Purity:97%Color and Shape:SolidMolecular weight:222.63(1H-Benzoimidazol-2-yl)-acetic acid
CAS:Formula:C9H8N2O2Purity:95%Color and Shape:SolidMolecular weight:176.175Methyl 6-amino-1H-benzo[d]imidazole-4-carboxylate
CAS:Formula:C9H9N3O2Purity:98%Molecular weight:191.195-Amino-1,3-dimethyl-1,3-dihydro-benzoimidazol-2-one
CAS:Formula:C9H11N3OPurity:95%Color and Shape:SolidMolecular weight:177.2075-Bromo-1-methyl-1H-indazole
CAS:Formula:C8H7BrN2Purity:97%Color and Shape:SolidMolecular weight:211.0624-Methyl-1H-benzimidazole-2-carboxylic acid
CAS:Formula:C9H8N2O2Purity:95%Color and Shape:SolidMolecular weight:176.1755-Bromo-1,6-dimethyl-1H-indazole
CAS:Formula:C9H9BrN2Purity:97%Color and Shape:Liquid, No data available.Molecular weight:225.089Ref: 10-F779467
1g524.00€5g1,350.00€10g2,024.00€25g4,652.00€100g16,292.00€2.5g987.00€100mg156.00€250mg224.00€500mg403.00€(R)-4-(Iodomethyl)oxazolidin-2-one
CAS:Formula:C4H6INO2Purity:96%Color and Shape:SolidMolecular weight:227.0016-(Trifluoromethyl)-1H-indazole-3-carbaldehyde
CAS:Formula:C9H5F3N2OPurity:97%Color and Shape:SolidMolecular weight:214.1471-(1H-benzimidazol-2-yl)ethanone
CAS:Formula:C9H8N2OPurity:97%Color and Shape:SolidMolecular weight:160.1765-Bromo-3-methyl-1H-indazole
CAS:Formula:C8H7BrN2Purity:95.0%Color and Shape:Solid, Pink powderMolecular weight:209.9792-(5-Amino-1H-indazol-1-yl)ethanol
CAS:Formula:C9H11N3OPurity:98%Color and Shape:SolidMolecular weight:177.2071-Butyl-3-methylimidazolium chloride
CAS:Formula:C8H15ClN2Purity:98%Color and Shape:Solid, Powder or Crystalline Powder or Solid or LumpsMolecular weight:174.671,3-Bis(2,6-di(pentan-3-yl)phenyl)-1H-imidazol-3-ium chloride
CAS:Purity:97%Molecular weight:537.2700195Methyl 5-amino-1H-imidazole-2-carboxylate
CAS:Formula:C5H7N3O2Purity:97%Color and Shape:Liquid, No data available.Molecular weight:141.134-(Trifluoromethyl)-1H-imidazole
CAS:Formula:C4H3F3N2Purity:95%Color and Shape:White powderMolecular weight:136.0772-Methylimidazole
CAS:Formula:C4H6N2Purity:98%Color and Shape:Solid, Powder or Crystalline Powder or Chunks or FlakesMolecular weight:82.1062,2-Difluoro-2-(1-methyl-1H-imidazol-2-yl)acetic acid, lithium salt
CAS:Purity:97%Molecular weight:183.061,3-Dicyclohexyl-1H-benzo[d]imidazol-3-ium chloride
CAS:Formula:C19H27ClN2Purity:98%Molecular weight:318.89(S)-3-Boc-2,2-Dimethyl-oxazolidine-4-carboxylic acid methyl ester
CAS:Formula:C12H21NO5Purity:98%Color and Shape:LiquidMolecular weight:259.3024-Chloro-3-iodo-1H-indazole
CAS:Formula:C7H4ClIN2Purity:98%Color and Shape:SolidMolecular weight:278.48Boc-His(Bom)-OH
CAS:<p>M03288 - Boc-His(Bom)-OH</p>Formula:C19H25N3O5Purity:97%Color and Shape:Solid, White powderMolecular weight:375.425Methyl 6-bromo-1H-indazole-3-carboxylate
CAS:Formula:C9H7BrN2O2Purity:95%Color and Shape:SolidMolecular weight:255.0715-(Trifluoromethoxy)-1H-indazole-3-carboxylic acid
CAS:Formula:C9H5F3N2O3Purity:95%Color and Shape:SolidMolecular weight:246.1451-Ethyl-3-methylimidazolium Hydrogen Sulfate
CAS:Purity:95%Color and Shape:LiquidMolecular weight:208.235-Bromo-1H-indazole-3-carbaldehyde
CAS:Formula:C8H5BrN2OPurity:95%Color and Shape:SolidMolecular weight:225.0453-Iodo-4-methyl-1H-indazole
CAS:Formula:C8H7IN2Purity:97%Color and Shape:SolidMolecular weight:258.0625-Methoxy-1H-indazole-3-carbaldehyde
CAS:Formula:C9H8N2O2Purity:98%Color and Shape:SolidMolecular weight:176.1752,4-Dibromo-1H-imidazole
CAS:Formula:C3H2Br2N2Purity:95%Color and Shape:SolidMolecular weight:225.8714,4-dimethyl-1,3-oxazolidin-2-one
CAS:Formula:C5H9NO2Purity:97%Color and Shape:CrystallineMolecular weight:115.1325-Hydroxybenzimidazole
CAS:Formula:C7H6N2OPurity:97%Color and Shape:Solid, PowderMolecular weight:134.138Di(1H-imidazol-2-yl)methanimine
CAS:Formula:C7H7N5Purity:95%Color and Shape:SolidMolecular weight:161.1681-(Methoxymethyl)-1H-imidazole
CAS:Formula:C5H8N2OPurity:97%Color and Shape:LiquidMolecular weight:112.1321-Ethyl-3-methylimidazolium Acetate
CAS:Formula:C8H14N2O2Purity:95%Color and Shape:Liquid, Clear or HazyMolecular weight:170.212Ethyl 1-methyl-5-nitroimidazole-2-carboxylate
CAS:Formula:C7H9N3O4Purity:98%Color and Shape:SolidMolecular weight:199.166Methyl 1-methyl-1H-imidazole-2-carboxylate
CAS:Formula:C6H8N2O2Purity:98%Color and Shape:SolidMolecular weight:140.1423-Hexadecyl-1-methyl-1H-imidazol-3-ium bromide
CAS:Formula:C20H39BrN2Purity:97%Color and Shape:SolidMolecular weight:387.452-Chloro-1-methyl-1H-benzoimidazole
CAS:Formula:C8H7ClN2Purity:95%Color and Shape:SolidMolecular weight:166.615-Nitro-1-methyl-1H-indazole
CAS:Formula:C8H7N3O2Purity:97%Color and Shape:SolidMolecular weight:177.1632-((1-Benzyl-1H-indazol-3-yl)oxy)acetic acid
CAS:Formula:C16H14N2O3Purity:95%Color and Shape:SolidMolecular weight:282.2994-Bromo-5-iodo-6-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
CAS:Purity:95%Molecular weight:421.076
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