Purines and Pyrimidine Derivatives
Purines have a bicyclic structure, consisting of a six-membered ring fused to a five-membered ring, both containing nitrogen atoms in key positions. Purine derivatives, such as adenine and guanine, are essential for the formation of DNA and RNA. These compounds have therapeutic applications in cancer and viral disease treatments by inhibiting cell replication. Pyrimidines, on the other hand, have a monocyclic six-membered structure with two nitrogen atoms. Their derivatives, such as cytosine, thymine, and uracil, are also essential components of DNA and RNA and are used in chemotherapy and antiviral treatments.
At CymitQuimica, we offer purine and pyrimidine derivatives for research in molecular biology, genomics, and the development of innovative therapies.
Found 8902 products of "Purines and Pyrimidine Derivatives"
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Tenofovir Disoproxil Isopropoxycarbonyl
CAS:<p>Stability Hygroscopic<br>Applications Tenofovir Disoproxil derivative as antiviral and antitumor agent.<br></p>Formula:C23H36N5O12PColor and Shape:White SolidMolecular weight:605.53Pemetrexed Sodium Methyl Ester
Controlled Product<p>Applications Pemetrexed Sodium Methyl Ester is an impurity of Pemetrexed(P219550). Pemetrexed Disodium Heptahydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.<br>References Vogelzang, N.J., et al.: J. Clin. Oncol., 21,2636 (2003); Paz-Ares, L., et al.: Lancet. Oncol., 13, 247 (2012);<br></p>Formula:C21H22N5NaO6Color and Shape:NeatMolecular weight:463.419(S)-4-(4-Aminobenzyl)-2-(1H)-oxazolidinone
CAS:Controlled Product<p>Impurity Zolmitriptan USP Related Compound G<br>Applications An intermediate of Zolmitriptan, as a novel inhibitor of the cytochrome P-450 enzyme aromatase. Zolmitriptan USP Related Compound G.<br>References Ahmed, S., et al.: Bioorg. Med. Chem. Lett., 5, 2789(1995), Ahmed, S., et al.: Drug. Des. Discov., 15, 239 (1998), Brodie, A., et al.: Steroids, 65, 171 (2000),<br></p>Formula:C10H12N2O2Color and Shape:NeatMolecular weight:192.21Tenofovir Alafenamide-d5 (Diastereomers)
CAS:Controlled ProductFormula:C212H5H24N6O5PColor and Shape:NeatMolecular weight:481.50Memantine Glycine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An impurity of the antiparkinsonian and antispasmodic agent Memantine (M218000).<br>References Rystov, L. et al.: J. Pharmac. Biomed. Anal., 56, 887 (2011);<br></p>Formula:C14H23NO2Color and Shape:NeatMolecular weight:237.341,3,7-Trimethyluric Acid-d3
CAS:Controlled Product<p>Stability Store in freezer<br>Applications A caffeine metabolite.<br>References Regal, K.A., et al.: J. of Chromatography B, 708, 75 (1998)<br></p>Formula:C82H3H7N4O3Color and Shape:NeatMolecular weight:213.21Purine
CAS:Controlled Product<p>Applications Purine (cas# 120-73-0) is a useful research chemical.<br></p>Formula:C5H4N4Color and Shape:NeatMolecular weight:120.11Tenofovir Phosphate Diammonia Salt, >90%
CAS:Controlled Product<p>Applications Tenofovir Phosphate Diammonia Salt is a metabolite of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Michelson, A.M., et al.: Biochim. Biophys. Acta, 91, 1 (1964); Rosenberg, I., et al.: Collect. Czeck. Chem. Commun., 50, 1507 (1985); Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005),; Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Formula:C9H21N7O7P2Purity:>90%Color and Shape:NeatMolecular weight:401.25Tenofovir Isopropyl Ethyl Diester
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Tenofovir Disopropyl Ethyl Diester is an impurity of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C18H28N5O10PColor and Shape:NeatMolecular weight:505.42(R)-9-[2-(Diethylphosphonomethoxy)propyl] Adenine
CAS:Controlled Product<p>Applications A acyclic phosphonate nucleotide.<br></p>Formula:C13H22N5O4PColor and Shape:White SolidMolecular weight:343.32Formaldehyde 2,4-Dinitrophenylhydrazone
CAS:<p>Stability Shock Sensitive<br>Applications Formaldehyde 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic aldehyde found in mainstream cigarette smoke.<br>References Delgado, B. et al.: J. Liq. Chrom. Rel. Technol., 31, 361 (2008); Miller, J.H. et al.: J. Chrom. Sci., 48, 12 (2010);<br></p>Formula:C7H6N4O4Color and Shape:NeatMolecular weight:210.15Urea-urethane Compound (~85%)
CAS:Controlled Product<p>Applications Urea-urethane Compound is a reaction product of 4,4'-sulfonylbis[benzenamine] and 2,4-TDI.<br></p>Formula:C42H36N6O8SPurity:~80%Color and Shape:NeatMolecular weight:784.84Zeatin
CAS:<p>Applications Zeatin belongs to the family of plant-growth hormones called cytokinins and it can be used for agricultural use as agrochemicals for increasing crop yields and regulate various aspects of plant growth and development.<br>References Koprna, R., et al.: Bioorgan. Med. Chem., 24, 484-492 (2016)<br></p>Formula:C10H13N5OColor and Shape:White To Off-WhiteMolecular weight:219.24Methotrexate-d3 Heptaglutamate Trifluoroacetate
CAS:Controlled ProductFormula:C50H61D3N14O23xC2HF3O2Color and Shape:NeatMolecular weight:1232.142Tri-o-tolyl-Phosphine Oxide
CAS:Controlled Product<p>Impurity Eletriptan Impurity 14<br>Applications Tri-o-tolyl-Phosphine Oxide (Eletriptan Impurity 14) is an impurity of Eletriptan, a selective serotonin 5-HT1B and 5-HT1D receptor agonist and used to treat migraines.<br>References Willems, E., et al.: Arch. Pharmacol., 358, 212 (1998); Napier, C., et al.: Eur. J. Pharmacol., 368, 259 (1999); Goadsby, P.J., et al.: Neurology, 54, 156 (2000)<br></p>Formula:C21H21OPColor and Shape:NeatMolecular weight:320.365
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