Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65580 products of "Quinazoline and Quinoline Derivatives"
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Deferiprone-d3 3-O-β-D-Glucuronide Sodium Salt
CAS:Controlled Product<p>Stability Very Hygroscopic<br>Applications A labelled metabolite of Deferiprone (D474000).<br>References Choudhury, R., et al.: Drug Metab. Dispos., 23, 314 (1995);<br></p>Formula:C13H13D3NNaO8Color and Shape:Off-White To Light BeigeMolecular weight:340.28(2-CHLOROPYRIDIN-4-YL)(1-ISOPROPYL-1H-PYRROLO[3,2-C]PYRIDIN-3-YL)METHANONE
CAS:Purity:95.0%Molecular weight:299.7600097656256-Bromo-2-phenylquinoline-4-carboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:328.16500854492191,2-Diphenyl Hydrazine
CAS:Controlled Product<p>Stability Air Sensitive (Oxidize)<br>Applications Impurity in the production of Phenylbutazone (P319570). Hydrazobenzene is a metabolic intermediate of Azobenzene.Carcinogenic.<br>References Chung, K., et al.: Mutation Res., 114, 269 (1983), Kawanishi, S., et al.: J. Biol. Chem., 261, 5952 (1986), Floyd, R., et al.: Carcinogenesis, 11, 1447 (1990), Shibutani, S., et al.: Nature, 349, 431 (1991),<br></p>Formula:C12H12N2Color and Shape:OrangeMolecular weight:184.24Nateglinide
CAS:Controlled Product<p>Applications An amino-acid derivative that stimulates insulin secretion. Used as an antidiabetic.<br>References Shinkai, H., et al.: J. Med. Chem., 32, 1436 (1989), Sato, Y., et al.: Diabetes Res. Clin. Pract., 12, 53 (1991), Vicent, D., et al.: J. Clin. Invest., 111, 1373 (2003), Ceriello, A., et al.: Diabet. Med., 21, 171 (2004),<br></p>Formula:C19H27NO3Color and Shape:White To Off-WhiteMolecular weight:317.422-(1-phenyl-1H-pyrazol-4-yl)cyclopropane-1-carboxylic acid
CAS:Purity:95.0%Molecular weight:228.251007080078128-chloro-2-phenylquinoline-4-carboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:283.70999145507814-Methoxy-2-(((6-methoxy-1H-benzo[d]imidazol-2-yl)sulfonyl)methyl)-3,5-dimethylpyridine 1-oxide
CAS:Purity:95.0%Molecular weight:377.4200134277344(4-Cyclohexyl)butyl 5-(1,3-dioxolan-2-yl)-2-thienyl ketone
CAS:Purity:97.0%Molecular weight:322.45999145507814-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone
CAS:Controlled Product<p>Impurity Rivaroxaban Impurity E<br>Applications 4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone (Rivaroxaban Impurity E) is an impurity of Rivaroxaban (R538000), which is a antithrombotic agent and a FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C13H17ClN2O3Color and Shape:NeatMolecular weight:284.745-Amino-1-benzo[1,3]dioxol-5-yl-1H-pyrazole-4-carbonitrile
Purity:95.0%Molecular weight:228.210998535156251-Phenyl-3-thiophen-2-yl-1H-pyrazole-5-carboxylic acid
CAS:Color and Shape:SolidMolecular weight:270.30999755859375Potassium Phthalimide
CAS:Controlled Product<p>Applications Potassium Phthalimide is a green, solid-base organocatalys.<br>References Kiyani, H., Ghiasi, M.: Chinese Chem. Lett., 25, 313 (2014)<br></p>Formula:C8H4NO2·KColor and Shape:NeatMolecular weight:185.222-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-Isoquinolinetriol Hemisulfate Hydrate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 2-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-Isoquinolinetriol Hemisulfate Hydrate is a salt form of 2-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-isoquinolinetriol (CAS 94120-05-5) which is used in analytical study of identification of degradation products and process impurities from terbutaline sulfate by UHPLC-Q-TOF-MS/MS and In silico toxicity prediction.<br>References Zhou, N., et al.: Chromatographia, 80, 793 (2017)<br></p>Formula:(C13H19NO3)•H2SO4•x(H2O)Color and Shape:NeatMolecular weight:2237.3098071802Intedanib
CAS:Controlled Product<p>Applications It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Formula:C31H33N5O4Color and Shape:NeatMolecular weight:539.624-(4-ETHYNYLPHENYL)MORPHOLINE
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:187.24200439453125(1,3-dimethyl-1H-pyrazol-5-yl)acetonitrile
CAS:Formula:C7H9N3Purity:97%Color and Shape:SolidMolecular weight:135.171-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:295.242004394531253-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS:Formula:C11H15BClNO2Purity:98%Molecular weight:239.517-chloro-4-methoxy-N-(pyridin-3-ylmethyl)benzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:305.77999877929694-Fluoro-3-(((5-(1-methyl-1H-pyrazol-3-yl)pyridin-3-yl)methyl)amino)-N-(3-(trifluoromethoxy)phenyl)benzamide
CAS:Purity:97.0%Molecular weight:485.4429931640625N-Desmethyl-N-cyclopentyl Tadalafil
CAS:Controlled Product<p>Applications N-Desmethyl-N-cyclopentyl Tadalafil is used as a reagent to synthesize tetracyclic cGMP-specific phosphodiesterase inhibitors, compounds that have potential to treat cardiovascular disorders and erectile dysfunction.<br>References Daugan, A. & Gellibert, F. Tetracyclic cGMP-specific Phosphodiesterase Inhibitors and Their Use in Disease Treatment. U.S. 6143746. Nov 7, 2000<br></p>Formula:C26H25N3O4Color and Shape:NeatMolecular weight:443.491-(4-Fluorophenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazole-4-carbaldehyde
CAS:Molecular weight:324.3110046386719rac trans-Loxoprofen Alcohol
CAS:<p>Applications The cis-alcohol metabolite of Loxoprofen (L472900).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Terada, A., et al.: J. Med. Chem., 27, 212 (1984), Sugimoto, M., et al.: Biochem. Pharmacol., 42, 2363 (1991), Riendeau, D., et al.: Bioorg. Med. Chem. Lett., 14, 1201 (2004),<br></p>Formula:C15H20O3Color and Shape:NeatMolecular weight:248.32(S)-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide
CAS:Purity:98%Molecular weight:401.44000244140625(2E)-3-[3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]-N-(pyridin-3-ylmethyl)prop-2-enamide
CAS:Molecular weight:398.4410095214844(R)-6,7-Dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)phenyl)thiophen-2-yl)ethyl)quinazolin-4-amine
CAS:Purity:98.0%Color and Shape:Liquid, No data available.Molecular weight:448.58999633789064-(4-Morpholinyl)-1,2,5-thiadiazol-3(2H)-one 1-Oxide
CAS:Controlled Product<p>Impurity Timolol EP Impurity G; Timolol BP Impurity G<br>Stability Moisture Sensitive<br>Applications 4-(4-Morpholinyl)-1,2,5-thiadiazol-3(2H)-one 1-Oxide (Timolol EP Impurity G; Timolol BP Impurity G) is an impurity of Timolol (T4437005), an antihypertensive, an adrenergic blocking agent (1); antiarrhythmic (class II); antianginal; antiglaucoma (2) and antihypertensive (3) agent.<br>References 1. Wasson, B. et al.: J. Med. Chem. 1972 Jun;15(6):651-5.2. Heel, R. et al.: Drugs. 1979 Jan;17(1):38-55.3. Rofman, et al.: Hypertension. 1980 Sep-Oct;2(5):643-8.<br></p>Formula:C6H9N3O3SColor and Shape:WhiteMolecular weight:203.22Ethyl 5-Pyridin-4-yl-1,2,4-oxadiazole-3-carboxylate
CAS:Purity:97.0%Molecular weight:219.1999969482422TERT-BUTYL ((4-BROMOTHIOPHEN-2-YL)METHYL)CARBAMATE
CAS:Formula:C10H14BrNO2SPurity:98.0%Color and Shape:SolidMolecular weight:292.195-Amino-1-(2-bromophenyl)-1H-pyrazole-4-carbonitrile
CAS:Purity:95.0%Molecular weight:263.0979919433594Nocodazole
CAS:<p>M05733 - Nocodazole</p>Formula:C14H11N3O3SPurity:98%Color and Shape:Solid, Beige powderMolecular weight:301.320007324218758-Methyl-2-pyridin-3-yl-quinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:264.283996582031252-[5-bromo-2-(pyridin-4-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Purity:95.0%Molecular weight:352.6600036621094N-(1-(2,6-DIFLUOROPHENYL)-1H-PYRAZOL-3-YL)ACETAMIDE
CAS:Purity:95.0%Molecular weight:237.21000671386726-ethyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.3699951171875Aprepitant
CAS:Controlled Product<p>Applications Aprepitant is a neurokinin-1 antagonist and an antiemetic agent (1). It is used to prevent chemotherapy-induced nausea and vomiting (CINV) in colorectal cancer patients (2) Aprepitant has also been shown to induce apoptotic cell death and G1 arrest through Akt/p53 axis in pre-B acute lymphoblastic leukemia cells (3).<br>References (1) Takemoto, H., et al.: nt J Clin Oncol (2016) (2) Bayati, S., et al.: Eur J Pharmacol. 791, 274 (2016) (3) Navari, R.M.: Expert Rev Anticancer Ther. 4, 715 (2004)<br></p>Formula:C23H21F7N4O3Color and Shape:Off-WhiteMolecular weight:534.433-Methyl-1-(3-methylphenyl)-1H-pyrazol-5-amine hydrochloride
CAS:Purity:97%Molecular weight:223.69999694824222-Phenylphenol
CAS:<p>Applications 2-Phenylphenol is an agricultural fungicide and is no longer used as a food additive (1). It has been associated with the incidence of bladder cancer in male rats which may be related to its primary metabolite, phenylhydroquinone (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Gouin T. et al.: Environ Pollut. 2012 Jun;165:208-14. 2. Balakrishnan, S. et al.: Environ Mol Mutagen. 2016 Apr;57(3):210-9<br></p>Formula:C12H10OColor and Shape:Light PinkMolecular weight:170.21Ref: 10-F469579
1gTo inquire2gTo inquire5gTo inquire10gTo inquire100mgTo inquire250mgTo inquire500mgTo inquire3-Bromomethyl-thiophene-2-carboxylic acid methyl ester
CAS:Purity:97.0%Color and Shape:Solid, Light yellow solidMolecular weight:235.10000610351562N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester Hydrochloride
CAS:Controlled Product<p>Applications Hydrochloride Salt of N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester is an intermediate in the preparation of angiotensin II type 1 receptor antagonists.<br>References Goossen, L.J. et al.: J. Org. Chem., 72, 7473 (2007); Nie, Y. et al.: Bioorg. Med. Chem., 20, 2747 (2012);<br></p>Formula:C20H22N2O2·ClHColor and Shape:NeatMolecular weight:358.864-Methoxy Moxonidine
CAS:Controlled ProductFormula:C10H15N5O2Color and Shape:GreyMolecular weight:237.26(1-oxo-4-phenyl-2(1H)-phthalazinyl)acetic acid hydrate
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:298.29800415039062-chloro-6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazoline
CAS:Purity:97.0%Molecular weight:369.6300048828125Ref: 10-F519250
1gTo inquire5gTo inquire10gTo inquire25gTo inquire100mgTo inquire250mgTo inquire500mgTo inquireDipyridamole-d20 (Major)
CAS:Controlled Product<p>Applications Selective inhibitor of phosphodiesterase V (PDE 5); potent coronary vasodilator drug; adenosine transport inhibitor; inhibitor of platelet aggregation.A representative lot was: 36% d20; 25% d19; 13%d18; 24% d17; 1% d16.<br>References Buchalter, M.B., et al.: Postgrad. Med. J., 66, 531 (1990), Sundaram, M., et al.: J. Biol. Chem., 273, 21519 (1998), Denis, D., et al.: Eur. J. Pharmacol., 367, 343 (1999),<br></p>Formula:C24H20D20N8O4Color and Shape:NeatMolecular weight:524.75C -(4-Chloro-2-ethyl-2 H -pyrazol-3-yl)-methylamine
CAS:Formula:C6H10ClN3Purity:98%Color and Shape:SolidMolecular weight:159.621-Adamantanamine Sulfate
CAS:<p>Stability Hygroscopic<br>Applications 1-Adamantanamine Sulfate (cas# 31377-23-8) is a useful research chemical.<br></p>Formula:(C10H17N)·H2SO4Color and Shape:NeatMolecular weight:2(151.25) + 98.083-(((5-Chloro-3-ethylpyrazolo[1,5-a]pyrimidin-7-yl)amino)methyl)pyridine 1-oxide
CAS:Purity:95%Molecular weight:303.75Medetomidine
CAS:<p>Medetomidine (MPV785 free base) is a selective α2-adrenoceptor agonist, with sedative and analgesic and vasoconstrictive hypoxic , in small animal anesthesia.</p>Formula:C13H16N2Purity:99.88%Color and Shape:SolidMolecular weight:200.28(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
CAS:Purity:95.0%Molecular weight:345.42001342773442-{[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-5,5-dimethylcyclohexane-1,3-dione
CAS:Molecular weight:404.8900146484375Lansoprazole Sulfide N-Oxide
CAS:<p>Applications Used in the preparation of Lansoprazole and its metabolite and impurities.<br>References Reddy, G. et al.; Synthetic Commun. 38, 3477 (2008)<br></p>Formula:C16H14F3N3O2SColor and Shape:Off White SolidMolecular weight:369.36Methyl-3-n propyl pyrazine
CAS:Formula:C8H12N2Purity:95.0%Color and Shape:LiquidMolecular weight:136.1985-O-Desmethyl Omeprazole Sulfide
CAS:Controlled ProductFormula:C16H17N3O2SColor and Shape:NeatMolecular weight:315.394-Hydroxybenzyl Alcohol
CAS:<p>Impurity Bisoprolol Alcohol Impurity<br>Applications 4-Hydroxybenzyl Alcohol is a reagent in the synthesis in a conjugate of calicheamicin used in the treatment of acute myeloid leukemia. Participates in the oxidation of phenols catalyzed by polyphenol oxidase. Also used in the preparation of antimalarial agents.<br>References Hamann, P. et al.: Bioconj. Chem., 13, 47 (2002); Kazandjian, R. et al.: J. Am. Chem. Soc., 107, 5448 (1995); Caldarelli, S. et al.: J. Med. Chem., 56, 496 (2013);<br></p>Formula:C7H8O2Color and Shape:NeatMolecular weight:124.14N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine
CAS:Purity:97.0%Molecular weight:348.72000122070312-(Piperazin-1-yl)acetic acid N-(3-pyridyl)amide trihydrochloride
CAS:Formula:C11H19Cl3N4OPurity:97.0%Color and Shape:SolidMolecular weight:329.65Roflumilast-d4 N-Oxide
CAS:Controlled Product<p>Applications Labelled Roflumilast-N-oxide (R639710). Roflumilast-N-oxide is the active metabolite of Roflumilast (R639700).<br>References Chiba, M., et al.: Drug Metab. Dispos., 25, 1022 (1997), Jarvis, B., et al.: Drugs, 59, 891 (2000),<br></p>Formula:C17H10D4Cl2F2N2O4Color and Shape:NeatMolecular weight:423.232-(2-Isopropylamino-thiazol-4-yl)-7-methoxy-quinolin-4-ol
CAS:Purity:97.0%Molecular weight:315.39001464843752-[5-bromo-2-(pyridin-2-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Purity:95.0%Molecular weight:352.6600036621094Ethyl 4-Nitrobenzoate
CAS:Controlled Product<p>Applications ETHYL 4-NITROBENZOATE (cas# 99-77-4) is a useful research chemical.<br></p>Formula:C9H9NO4Color and Shape:White To Light YellowMolecular weight:195.174-((3-Chloro-2,4-difluorophenyl)amino)-7-methoxyquinazolin-6-ol
CAS:Purity:97.0%Molecular weight:337.7099914550781rac N-Acetyl-Pseudoephedrine
CAS:Controlled Product<p>Applications rac N-Acetyl Pseudoephedrine is a racemic N-acetylated analogue of the non-selective adrenergic agonist Pseudoephedrine (P839350).<br>References Coutts, R.T. et al.: Biomed. Mass Spec., 11, 441 (1984);<br></p>Formula:C12H17NO2Color and Shape:NeatMolecular weight:207.272-Amino-5-bromo-6-iodopyridine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:298.908996582031254-Hydroxybenzaldehyde
CAS:Controlled Product<p>Impurity Bisoprolol EP Impurity S<br>Stability Hygroscopic<br>Applications 4-Hydroxybenzaldehyde (Bisoprolol EP Impurity S) maintains bactericidal activity when tested against certain bacteria strains. It also displays antioxidant potential when analyzed through assay.<br>References Friedman, M. et al.: J. Food. Prot., 66, 1811 (2003); Liu, L. et al.: Chem. Nat. Comp., 48, 785 (2012);<br></p>Formula:C7H6O2Color and Shape:BeigeMolecular weight:122.12Oxyphenbutazone
CAS:<p>Oxyphenbutazone: Non-selective COX inhibitor, anti-inflammatory, kills dormant Mycobacterium tuberculosis.</p>Formula:C19H20N2O3Purity:99.41% - 99.88%Color and Shape:White To Yellowish White Crystalline Powder SolidMolecular weight:324.37(S)-6-((2-(Thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
CAS:Purity:97.0%Molecular weight:273.39001464843754’-(Bromomethyl)biphenyl-2-carboxylic Acid tert-Butyl Ester
CAS:Controlled Product<p>Impurity Telmisartan EP Impurity H<br>Applications 4’-(Bromomethyl)biphenyl-2-carboxylic Acid tert-Butyl Ester (Telmisartan EP Impurity H) is a biphenyl derivative used in the preparation of angiotensin II receptor antagonists. T017000<br>References Wahhab, A. et al.: Arzneim.-Forsch., 43, 1157 (1993); Yanagisawa, H. et al.: J. Med. Chem., 39, 323 (1996);<br></p>Formula:C18H19BrO2Color and Shape:NeatMolecular weight:347.258-propyl-4-(pyridine-3-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Purity:95.0%Molecular weight:333.38800048828125
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