Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65576 products of "Quinazoline and Quinoline Derivatives"
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Benzydamine-d6 N-Oxide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A labelled metabolite of Benzydamine (B209950).<br>References Beaty, N., et al.: J. Biol. Chem., 255, 3817 (1980), Tugnait, M., et al.: Drug Metab. Dispos., 25, 524 (1997), Ubeaud, G., et al.: Eur. J. Pharm. Sci., 8, 255 (1999),<br></p>Formula:C19H17D6N3O2Color and Shape:NeatMolecular weight:331.44N-(2-Succinyl) Phenylephrine(Mixture of Diastereomers) ( >85%)
CAS:<p>Impurity N-(2-Succinyl) Phenylephrine Impurity<br>Applications The major degradation product identified in Acetaminophen, Phenylephrine hydrochloride, and Chlorpheniramine maleate.<br>References Wong, J., et al.: Anal. Chem., 78, 7891 (2006),<br></p>Formula:C13H17NO6Purity:>85%Color and Shape:NeatMolecular weight:283.28rac-4-Hydroxy Propranolol Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications rac-4-Hydroxy Propranolol Hydrochloride is a metabolite of Propranolol.<br>References Walle, T., et al.: Drug Metab. Dispos., 13, 204 (1985), Mason, R., et al.: J. Med. Chem., 34, 869 (1991), Anderson, R., et al.: Biochem. Pharmacol., 52, 341 (1996), Hung, D., et al.: J. Pharmacol. Exp. Ther., 297, 780 (2001),<br></p>Formula:C16H21NO3·ClHColor and Shape:NeatMolecular weight:311.803-(1,3-benzodioxol-5-yl)-1H-pyrazole hydrochloride
CAS:Purity:95.0%Molecular weight:224.639999389648442-(5-amino-3-cyclopropyl-1H-pyrazol-1-yl)-5-ethyl-6-methylpyrimidin-4(3H)-one
CAS:Purity:95.0%Molecular weight:259.312988281252-(4-t-Butylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Purity:97.0%Molecular weight:316.4200134277344rac-Naproxen-13C,d3
CAS:Controlled Product<p>Applications Labelled Naproxen. An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Formula:CC132H3H11O3Color and Shape:NeatMolecular weight:234.27α-Hydroxy Montelukast
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A hydroxylated impurity of the selective leukotriene D4-receptor antagonist, Montelukast (M568000).<br></p>Formula:C35H36ClNO4SColor and Shape:NeatMolecular weight:602.18(R)-(+)-Thalidomide
CAS:Controlled Product<p>Applications Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative.<br>References D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)<br></p>Formula:C13H10N2O4Color and Shape:NeatMolecular weight:258.233-(3-methoxyphenyl)-1-methyl-1{H}-pyrazole-5-carboxylic acid
CAS:Purity:95.0%Molecular weight:232.238998413085942-Keto Crizotinib
CAS:Controlled Product<p>Applications 2-Keto Crizotinib is an impurity of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C21H20Cl2FN5O2Color and Shape:NeatMolecular weight:464.327-Bromo-2-chloro-3-methylquinoline
CAS:Formula:C10H7BrClNPurity:97%Color and Shape:No data available.Molecular weight:256.53Nitrofurantoin
CAS:Controlled Product<p>Applications A nitrofuran antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976), Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004),<br></p>Formula:C8H6N4O5Color and Shape:Light Yellow To YellowMolecular weight:238.163’-Amino-2’-Hydroxy-[1,1’]biphenyl-3-carboxylic Acid
CAS:Controlled Product<p>Applications 3’-Amino-2’-Hydroxy-[1,1’]Biphenyl-3-carboxylic Acid is used in the synthesis of monoethanolamine salts. A hydrazine cleavage product from Eltrombopag (E508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia<br>References Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008),<br></p>Formula:C13H11NO3Color and Shape:NeatMolecular weight:229.2316-Methyl-5-((3-(2-(methylthio)pyrimidin-4-yl)pyridin-2-yl)oxy)naphthalen-1-amine
CAS:Purity:98%Molecular weight:374.45999145507813-(2,6-Dimethylmorpholino)-1,1,1-trifluoro-2-propanol
CAS:Formula:C9H16F3NO2Color and Shape:SolidMolecular weight:227.227Ref: 10-F025806
1gTo inquire2gTo inquire5gTo inquire10gTo inquire100mgTo inquire250mgTo inquire500mgTo inquireN-{2-chloropyrrolo[2,1-f][1,2,4]triazin-4-yl}-5-cyclopropyl-1H-pyrazol-3-amine
CAS:Purity:95.0%Molecular weight:274.70999145507814-ethoxy-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:285.3699951171875(E)-2-((1-Acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide (Axitinib Impurity)
CAS:Purity:97%Color and Shape:SolidMolecular weight:428.51(R)-Albuterol Hydrochloride
CAS:Controlled Product<p>Applications The R-enantiomer of Albuterol (A514500). A β2-adrenoceptor agonist. Bronchodilator; tocolytic.<br>References Han, et al.: Bioorg. Med. Chem., 14, 6043 (2006), Liyou, H., et al.: Biochem., 46, 1432 (2007), Agrawal, D., et al.: J. Allergy Clin. Immunol., 113, 503 (2004),<br></p>Formula:C13H21NO3·ClHColor and Shape:Off-WhiteMolecular weight:275.77Dimepranol-d6
CAS:Controlled Product<p>Stability Volatile<br>Applications Labelled analiogue of Dimepranol, a component of Inosine pranobex (I822350) that produces a small but significant inhibition of the histamine release from human mast cells. Dimepranol is one of the compounds used to identify the illegal manufacture of methadone.<br>References Gielsdorf, W. et al.: Arch. Kriminol., 164, 83 (1979); Schmutzler, W. et al.: Int. Arch. Allergy Appl. Immunol., 88, 244 (1989);<br></p>Formula:C5H7D6NOColor and Shape:NeatMolecular weight:109.2N-Nitroso Iminostilbene
CAS:Controlled Product<p>Applications N-Nitroso Iminostilbene is derived from Iminostilbene (I445000), which is a metabolite of Carbamazepine (CBZ) (C175840).<br>References Lertratanangkoon, K., et al.: Drug Metab. Dispos., 10, 1 (1982), Deleu, D., et al.: Eur. J. Clin. Pharmacol., 57, 243 (2001)<br></p>Formula:C14H10N2OColor and Shape:NeatMolecular weight:222.24Acalabrutinib
CAS:Controlled Product<p>Applications Acalabrutinib, is an experimental anti-cancer drug and a selective Bruton's tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL).<br>References Byrd; et al. (2015). "Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia."; "AstraZeneca to buy Acerta for blood cancer drug". www.rsc.org. Chemistry World - Royal Society of Chemistry. Retrieved 24 December 2015.<br></p>Formula:C26H23N7O2Color and Shape:NeatMolecular weight:465.515-CYCLOPROPYL-1-(3,5-DICHLORO-PYRIDIN-4-YL)-1H-[1,2,3]TRIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER
CAS:Purity:90.0%Molecular weight:327.1700134277344Oclacitinib
CAS:<p>Applications Oclacitinib is a novel Janus kinase (JAK) inhibitor with activity against cytokines involved in allergy.<br>References Gonzales, A.J., et al.: J. Vet. Pharmacol. Ther., 37, 317 (2014)<br></p>Formula:C15H23N5O2SColor and Shape:NeatMolecular weight:337.446-(1-ethyl-3,5-dimethyl-1H-pyrazol-4-yl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:313.36099243164066-methyl-2-(2-thienyl)quinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:269.32000732421875Ethyl 6-ethynylpicolinate
CAS:Formula:C10H9NO2Purity:98%Color and Shape:Liquid, No data available.Molecular weight:175.187Marbofloxacin
CAS:<p>Applications Fluorinated quinolone antibacterial.<br>References Gruet, P., et al.: Vet. Rec., 140, 199 (1977), Lefebvre, H.P., et al.: J. Vet. Pharmacol. Ther., 21, 453 (1998),<br></p>Formula:C17H19FN4O4Color and Shape:Off-WhiteMolecular weight:362.36N,N’-Desethylene Ofloxacin Hydrochloride
CAS:Controlled Product<p>Impurity Ofloxacin Desethylene Impurity<br>Applications N,N’-Desethylene Ofloxacin Hydrochloride is an Ofloxacin (O245750) derivative.<br></p>Formula:C16H19ClFN3O4Color and Shape:NeatMolecular weight:371.793,4-Bis(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)benzamide
CAS:Purity:98%Molecular weight:407.2900085449219Cycloheptyl 5-(1,3-dioxolan-2-yl)-2-thienyl ketone
CAS:Purity:97.0%Molecular weight:280.3800048828125Diclazuril 6-Carboxylic Acid
CAS:Controlled Product<p>Applications Diclazuril 6-Carboxylic Acid is an impurity of Diclazuril (D436200), a nucleotide analog with broad-spectrum anticoccidial activity.<br>References Fodey, T.L., et al.: J. Immunol. Meth., 323, 31 (2007);<br></p>Formula:C18H9Cl3N4O4Color and Shape:NeatMolecular weight:451.652-Methyl-N-[3-(trifluoromethyl)phenyl]propanamide
CAS:Controlled ProductFormula:C11H12F3NOColor and Shape:NeatMolecular weight:231.21Desmethyl Fondenafil
CAS:<p>Applications Desmethyl Fondenafil is an impurity of the drug Fondenafil/Carbodenafil (F685400) a Sildenafil (S435000) related compound found in health foods.<br>References Hamilton, et al.: J. Med. Chem., 30, 91 (1987),<br></p>Formula:C23H30N6O3Color and Shape:White To Light BeigeMolecular weight:438.525-(Aminosulfonyl)-2-methoxy-benzoic Acid Methyl Ester
CAS:<p>Impurity Sulpiride EP impurity B<br>Applications A reactant used in the preparation of many pharmaceutical compounds used as anticoagulants, HCV NS5B polymerase inhibitors, therapeutic drugs for treatment of neurodegenerative diseases and oral hypoglycemic agents.<br></p>Formula:C9H11NO5SColor and Shape:White To Off-WhiteMolecular weight:245.25N-Formyl Lenalidomide
CAS:Controlled ProductFormula:C14H13N3O4Color and Shape:NeatMolecular weight:287.27O-Desmethyl Astemizole
CAS:Controlled Product<p>Applications A metabolite of Astemizole.<br>References Nagata, K., et al.: J. Biol. Chem., 268, 24720 (1993), Benton, R., et al.: Clin. Pharmacol. Ther., 59, 383 (1996), Hashizume, T., et al.: Drug Metab. Dispos., 26, 566 (1998), Scarborough, P., et al.: Drug Metab. Rev., 31, 205 (1999),<br></p>Formula:C27H29FN4O·ClHColor and Shape:NeatMolecular weight:481.002-Pyridin-2-yl-benzofuran-5-carboxylic acid methyl ester
Purity:95.0%Molecular weight:253.2570037841797(2-methoxyethyl)(2-thienylmethyl)amine hydrochloride
CAS:Formula:C8H14ClNOSColor and Shape:SolidMolecular weight:207.722-Methyl-2-propyl-1,3-propanediol
CAS:Controlled Product<p>Applications An intermediate in the synthesis of Carisoprodol.<br></p>Formula:C7H16O2Color and Shape:NeatMolecular weight:132.203-(2-Methoxyphenyl)-1-phenyl-1H-pyrazole-4-carboxylic acid
CAS:Purity:98%Molecular weight:294.30999755859375N-(3-Chlorophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:352.22000122070312-Hydroxy-6-(trifluoromethyl)nicotinamide
CAS:Formula:C7H5F3N2O2Purity:≥97%Color and Shape:SolidMolecular weight:206.1244-Phenyl-5-trifluoromethyl-thiophene-2-carboxylic acid methyl ester
CAS:Formula:C13H9F3O2SPurity:95.0%Color and Shape:LiquidMolecular weight:286.274-[[4-Fluoro-3-(1-piperazinylcarbonyl)phenyl]methyl]-1(2H)-phthalazinone
CAS:Controlled ProductFormula:C20H19FN4O2Color and Shape:Off-WhiteMolecular weight:366.39Domperidone N-Oxide
CAS:Controlled Product<p>Impurity Domperidone EP Impurity C<br>Stability Hygroscopic<br>Applications Domperidone N-Oxide (Domperidone EP Impurity C) is an oxygenated metabolite of the gastrokinetic and antinauseant drug Domperidone (D531100).<br>References Van Vaeck, L. et al.: Biomed. Env. Mass Spec., 16, 121 (1988);<br></p>Formula:C22H24ClN5O3Color and Shape:White To Off-WhiteMolecular weight:441.91Mequitazine
CAS:Controlled Product<p>Applications It is an antihistamine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Uzan, A., et al.: Xenobiotica, 6, 633 (1976), Persi, L., et al.: Alergy, 52, 451 (1997), Nakamura, K., et al.: J. Pharmacol. Exp. Ther., 284, 437 (1998), Theunissen, E., et al.: Clin. Exp. Allergy, 34, 250 (2004),<br></p>Formula:C20H22N2SColor and Shape:NeatMolecular weight:322.47N-Nitroso Desmethyl Rizatriptan
Controlled ProductFormula:C14H16N6OColor and Shape:NeatMolecular weight:284.316Noradrenalone Hydrochloride
CAS:Controlled Product<p>Applications Noradrenalone Hydrochloride is an intermediate of Norepinephrine (N674500), an antagonist of dibutyryl cyclic AMP in the regulation of narcosis. Norepinephrine modulates human dendritic cell activation by altering cytokine release.<br>References Strobel, G., et. al.: Eur. J. Biochem., 176, 397 (1988); Piguet, P., et al.: J. Exp. Med., 173, 673 (1991); Hosoi, J., et al.: Nature, 363, 159 (1993); Elenkov, I., et al.: Pharmacol. Rev., 52, 595 (2000); Kaplan, D., et al.: Immunity, 23, 611 (2005)<br></p>Formula:C8H10ClNO3Color and Shape:Dark Yellow To Dark BrownMolecular weight:203.625-(1,3-Dioxolan-2-yl)-2-(4-nitrobenzoyl)thiophene
CAS:Purity:97.0%Molecular weight:305.299987792968753-(4-((1H-IMIDAZOL-1-YL)METHYL)PHENYL)-N-(TERT-BUTYL)THIOPHENE-2-SULFONAMIDE
CAS:Purity:95.0%Molecular weight:375.510009765625TERT-BUTYL (4-(6-(1-METHYL-1H-PYRAZOL-4-YL)PYRROLO[2,1-F][1,2,4]TRIAZIN-4-YL)PHENYL)CARBAMATE
Purity:95.0%Molecular weight:390.4469909667969N-Methyl-N,N-bis(2-pyridylethyl)amine
CAS:<p>Impurity Betahistine EP Impurity C (Free Base)<br>Applications N-Methyl-N,N-bis(2-pyridylethyl)amine is used as a reagent in the preparation of copper pyridylmethylethylenediamine dicyanamido polymeric complexes.<br>References Mautner, F.A. et al.: Inorg. Chim. Acta, 362, 4073 (2009);<br></p>Formula:C15H19N3Color and Shape:NeatMolecular weight:241.33ent-Valsartan
CAS:<p>Impurity Valsartan USP Related Compound A<br>Applications ent-Valsartan (Valsartan USP Related Compound A) is the (R)-enantiomer of Valsartan (V095750).<br>References Corea, L., et al.: Clin. Pharmacol. Ther., 60, 341 (1996), Satana, E;., et al.: J. Pharm. Biomed. Anal., 25, 1009 (2001), Sironi, L., et al.: Hypertension, 37, 961 (2001),<br></p>Formula:C24H29N5O3Color and Shape:WhiteMolecular weight:435.52[2-(1H-indol-3-yl)ethyl](3-pyridinylmethyl)amine hydrobromide
CAS:Purity:95.0%Molecular weight:332.24499511718753-(1-Pyridin-4-yl-3,4-dihydroisoquinolin-2(1H)-yl)propanoic acid
CAS:Purity:90.0%Molecular weight:282.34298706054695-Nitro-1 H -pyrazole-3-carboxylic acid (2-amino-ethyl)-amide
CAS:Formula:C6H9N5O3Color and Shape:SolidMolecular weight:199.171-Chloro-2,4-dinitrobenzene
CAS:Controlled Product<p>Applications 1-Chloro-2,4-dinitrobenzene is a benzene derivative and is used in biochemical research as a substrate for glutathione S-transferase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viswanathan, R., et al.: BIoconjugate. Chem., 24, 571 (2013); Ormazabal-Toledo, R., et al.: J. Org. Chem., 78, 1091 (2013);<br></p>Formula:C6H3ClN2O4Color and Shape:NeatMolecular weight:202.55Abemaciclib-D8
CAS:Controlled ProductFormula:C27D8H24F2N8Color and Shape:NeatMolecular weight:514.6433-Isopropylamino-1,2-propanediol
CAS:<p>Impurity Metoprolol EP Impurity N<br>Applications 3-Isopropylamino-1,2-propanediol (Metoprolol EP Impurity N) is a versatile organic building block, used in different chemical synthesis. It is used in the preparation of heterocyclic propanolamines, which are shown to have β-adrenergic antagonist activity.<br>References Dean, V. et al.: Drug Design and Discovery,10, 89 (1993);<br></p>Formula:C6H15NO2Color and Shape:ColourlessMolecular weight:133.19Desfluoro Fluvoxketone
CAS:Controlled Product<p>Applications Desfluoro Fluvoxamine intermediate.<br></p>Formula:C13H16F2O2Color and Shape:NeatMolecular weight:242.26rac N-Methyl Atomoxetine Oxalate
CAS:<p>Applications rac N-Methyl Atomoxetine Oxalate is a derivative of Atomoxetine which acts as a norepinephrine reuptake inhibitor.<br>References Farid, N.A., et al.: J. Clin. Pharmacol., 25, 296 (1985), Gehlert, D.R., et al.: J. Neurochem., 64, 2792 (1995), Hwamg. et al.: Neurosci. Lett., 265, 151 (1999), Ring, B.J., et al.: Drug Metab. Dispos., 30, 319 (2002),<br></p>Formula:C18H23NO·C2H2O4Color and Shape:Off White SolidMolecular weight:359.42Ranitidine
CAS:<p>Applications Ranitidine (cas# 66357-35-5) was used as a standard for testing the therapeutic effect of brown propolis extract against aspirin and ethanol- induced gastric ulcers.<br>References Patil, M., et al.: Eur. J. Biomed. Pharma. Sci., 7, 620 (2020)<br></p>Formula:C13H22N4O3SColor and Shape:NeatMolecular weight:314.40(1,3-benzodioxol-5-ylmethyl)(3-pyridinylmethyl)amine hydrobromide
CAS:Purity:95.0%Molecular weight:323.19000244140625Ref: 10-F547198
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquire2-(3-Difluoromethyl-5-methyl-pyrazol-1-yl)-propionic acid ethyl ester
CAS:Formula:C10H14F2N2O2Purity:97%Color and Shape:LiquidMolecular weight:232.231m-Ranolazine
CAS:Controlled Product<p>Applications m-Ranolazine is an impurity of Ranolazine Ethyl Dimer is an impurity of Ranolazine (R122500), an anti-ischemic agent which modulates myocardial metabolism. Antianginal.<br>References Chaitman, B.R., et al.: J. Am. Coll. Cardial., 43, 1375 (2004), McCormack, J.G., et al.: Gen. Pharmacol., 30, 639 (1998), Schofield, J.A.H., et al.: Expert Opin. Invest. Drugs, 11, 117 (2002),<br></p>Formula:C24H33N3O4Color and Shape:NeatMolecular weight:427.536(S)-Ibrutinib
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications (S)-Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.<br>References Pan, Z., et. al.: ChemMedChem, 2, 58 (2007)<br></p>Formula:C25H24N6O2Color and Shape:NeatMolecular weight:440.52-[5-(3-bromophenyl)-1H-pyrazol-3-yl]-5-methylphenol
CAS:Purity:95.0%Molecular weight:329.1969909667969N-(3-Morpholinopropyl) Gefitinib
CAS:Controlled Product<p>Applications N-(3-Morpholinopropyl) Gefitinib is a Gefitinib (G304000) impurity. It can also be synthesized from O-Desmorpholinopropyl Gefitinib (D296830).<br>References Anderson, N.G., et al.: Int. J. Cancer, 94, 774 (2001); Hirata, A., et al.: Cancer Res., 62, 2554 (2002); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003); Tamura, K., et al.: Expert Opin. Pharmacother., 6, 985 (2005); Ranson, M., et al.: J. Clin. Oncology, 20, 2240 (2002); Mendelsohn, J., et al.: J. Clin. Oncology, 21, 2787 (2003); McKillop, D., et al.: Xenobiotica, 10, 917 (2004);<br></p>Formula:C29H37ClFN5O4Color and Shape:NeatMolecular weight:574.087LEE 011
CAS:Controlled Product<p>Applications LEE 011 can be used in biological study of kinome-wide RNA interference screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition in ER-positive breast cancer.<br>References Jansen, V. M., et al.: Cancer Research, 77, 2488 (2017)<br></p>Formula:C23H30N8OColor and Shape:Light Yellow To BeigeMolecular weight:434.54
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