Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65576 products of "Quinazoline and Quinoline Derivatives"
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2-[3-(4-nitrophenyl)-1-phenyl-1h-pyrazol-4-yl]acetic acid
CAS:Purity:97%Molecular weight:323.30801391601565-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
CAS:Purity:95.0%Molecular weight:367.36999511718752-Pyridin-3-yl-benzofuran-5-carboxylic acid methyl ester
Purity:95.0%Molecular weight:253.2570037841797Nafronyl
CAS:<p>Applications Nafronyl is a selective inhibitor of serotonin receptors. Nafronyl is a vasodilator used in the treatment of intermittent claudication.<br>References Fontaine, et al.: Chim. Ther., 4, 44 (1969), Bessin, P., et al.: Eur. J. Med. Chem., 10, 291 (1975), Clyne, C.A., et al.: Br. J. Surg., 67, 347 (1980),<br></p>Formula:C24H33NO3Color and Shape:NeatMolecular weight:383.521-(Mercaptomethyl)cyclopropaneacetic Acid
CAS:Controlled Product<p>Applications An intermediate of Montelukast.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C6H10O2SColor and Shape:NeatMolecular weight:146.218-chloro-2-pyridin-4-ylquinoline-4-carboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:284.70001220703125Cyclopentynafil
CAS:Controlled ProductFormula:C26H36N6O4SColor and Shape:White SolidMolecular weight:528.67Dehydropinaverium Bromide
CAS:<p>Applications 4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethoxy]ethyl]morpholinium Bromide (1:1), is the derivative of Pinaverium Bromide (P465000), which is spasmolytic agent with low incidence of anticholinergic effects. It is a drug used for functional gastrointestinal disorders.<br>References Jacquot, C., et al.: Eur. J. Med. Chem., 13, 61 (1978), Bretaudeau, J., et al.: J. Pharmacol., 11, 233 (1980), Bertrand, J., et al.: Therapie, 36, 555 (1981),<br></p>Formula:C26H39BrNO4·BrColor and Shape:NeatMolecular weight:589.403-acetyl-6-fluoro-4-(4-fluorophenyl)quinolin-2(1H)-one
CAS:Purity:95.0%Molecular weight:299.2770080566406N-(3-Chloro-2-methylphenyl)-2-hydroxynicotinamide
CAS:<p>Applications An impurity of Clonixine (L488530). Clonixine is a nonsteroidal anti-inflammatory agent used as an analgesic.<br>References Ting, P., et al.: J. Med. Chem., 33, 2697 (1990),<br></p>Formula:C13H11ClN2O2Color and Shape:Off-White To Light YellowMolecular weight:262.69Clofentezine
CAS:Controlled Product<p>Applications Clofentezine is a mite growth regular and an tetrazine based acaricide. Clofentezine is used in agriculture for the protection of ornamentals, food and non-food crops in the field.Used as a standard for Pesticide detection. Clofentezine is used in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bakirci, G.T., et al.; Food. Chem., 135, 1901 (2012); Ay, R., et al.: Insect. Sci., 18, 503 (2011);<br></p>Formula:C14H8Cl2N4Color and Shape:NeatMolecular weight:303.154-Hydroxybenzhydrazide
CAS:Controlled Product<p>Applications 4-Hydroxybenzhydrazide works as an indicator in the determination of carbohydrates. Tissue (liver) bounded 4-Hydroxybenzhydrazide, the acid-hydrolyzable side chain of Nifuroxazide (N458500) can be used as a marker to monitor it’s residue in chicken.<br>References Lever, M., et al.: Anal. Biochem., 139, 205 (1984); Rocco, M., et al.: Anal. Biochem., 377, 251 (2008); Gao, F., et al.: J. Sci. Food Agr., 93, 2172 (2013)<br></p>Formula:C7H8N2O2Color and Shape:WhiteMolecular weight:152.15N-[4-Fluoro-3-(prop-2-enamido)phenyl]-1-(2-fluorophenyl)-1H-pyrazole-4-carboxamide
CAS:Purity:98.0%Molecular weight:368.3439941406251,4-Butane Sultone
CAS:<p>Applications 1,4-Butane Sultone is an alkylating agent with weak carcinogenic activity.<br>References Van Duuren, B.L. et al.: J. Nat. Cancer Inst., 53, 696 (1974); Druckrey, H. et al.: Zeitsch. Krebsforsch.,75, 69 (1970);<br></p>Formula:C4H8O3SColor and Shape:Colourless ViscousMolecular weight:136.17N-Nitroso Betahistine
CAS:<p>Applications N-Nitroso Betahistine is an impurity of Betahistine, which is most commonly used to treat the symptoms of Ménière's disease and vertigo. Vasodilator.<br>References Gilligan, P., et al.: J. Med. Chem., 43, 1641 (2000), Keller, P., et al.: Bioorg. Med. Chem., 8, 1213 (2000), Hauger, R., et al.: Pharmacol. Rev., 55, 21 (2003), Han, X., et al.: Bioorg. Med. Chem. Lett., 15, 3870 (2005)<br></p>Formula:C8H11N3OColor and Shape:Colourless To Light YellowMolecular weight:165.1922-Bromoacetic Acid
CAS:<p>Applications Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);<br></p>Formula:C2H3BrO2Color and Shape:Light YellowMolecular weight:138.953-(4-methylphenyl)-1-phenyl-1H-pyrazole-4-carboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:278.3110046386719N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-chloromethyl Benzamide
CAS:Controlled Product<p>Applications Gleevec Impurity<br></p>Formula:C24H20ClN5OColor and Shape:Off WhiteMolecular weight:429.903(4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one
CAS:Controlled Product<p>Applications AMDP3 (4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one) acts as a cardiac troponin effecter, resulting in activation of cardiac muscle contractions. It’s an analogue to Levosimendan (L378000), positive inotropic agent with vasodilating activity.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995), Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996); Robertson, I. et al.: Biochem., 47, 7485 (2008);<br></p>Formula:C11H13N3OColor and Shape:Light Yellow To BrownMolecular weight:203.24Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate
CAS:Purity:95.0%Molecular weight:351.4599914550781trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol
CAS:<p>Applications trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol is an impurity of Ambroxol (A575900), a bronchosecretolytic drug and a metabolite of Bromohexine.<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>Formula:C13H19BrN2OColor and Shape:NeatMolecular weight:299.21(4R-cis)-6-Chloromethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
CAS:Controlled Product<p>Applications A HMG-CoA reductase inhibitor intermediate.<br>References Hummel, W., et al.: J. Microbiol. Methods, 9, 201 (1989), Jendralla, H., et al.: J. Med. Chem., 34, 2962 (1991), Vicenzi, J., et al.: Enzyme Microb. Technol., 20, 494 ( 1997),<br></p>Formula:C13H23ClO4Color and Shape:NeatMolecular weight:278.775,6-Dehydro-17a-Dutasteride
Controlled Product<p>Applications 5,6-Dehydro-17α-dutasteride is an epimer of 5,6-Dehydro-17β-dutasteride (D229560) an impurity in the synthesis of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Formula:C27H28F6N2O2Color and Shape:NeatMolecular weight:526.51Furagin
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Furagin (a nitrofurantoin analog) has the same efficacy in treating acute cystitis as Ciprofloxacin, however the duration of therapy is longer. Antibacterial.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Agace, W., et al.: J. Clin. Invest., 92, 780 (1993); Lawrenson, R., et al.: J. Antimicrob. Chemother., 48, 895 (2001); Dalhoff, A., et al.: Lancet Infect. Dis., 3, 359 (2003); Thumbikat, P., et al.: J. Immunol., 176, 3080 (2006);<br></p>Formula:C10H8N4O5Color and Shape:NeatMolecular weight:264.19N-Nitroso Desmethyldiphenhydramine
CAS:Controlled ProductFormula:C16H18N2O2Color and Shape:NeatMolecular weight:270.3261-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
CAS:Controlled Product<p>Impurity Pethidine impurity B<br>Applications 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine is a dopaminergic neurotoxin that reportedly causes a severe and irreversible Parkinsonian condition in humans and monkeys.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Burns, R.S., et al.: Proc. Natl. Acad.Sci. USA, 80, 4546 (1983), Langston, J.W., et al.: Science, 219, 979 (1983), Mogi, M., et al.: Neurosci. Lett., 250, 25 (1998), Przedborski, S. and Jackson-Lewis, V., Mov. Disord., 13, 35 (1998),<br></p>Formula:C12H15NColor and Shape:NeatMolecular weight:173.25Vortioxetine
CAS:Controlled Product<p>Applications Vortioxetine can be used in biological study of effectiveness of long term vortioxetine treatment of patients with major depressive disorder.<br>References Vieta, E., et al.: Eur Neuropsychopharm (2017)<br></p>Formula:C18H22N2SColor and Shape:NeatMolecular weight:298.45Lodenafil Carbonate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Lodenafil carbonate is a new PDE-5 inhibitor used for oral therapy in erectile dysfunction.<br>References Rosen, R., et al.: Urology, 49, 822 (1997), Chew, K., et al.: J. Sex Med., 5, 928 (2008), Teixeira, C., et al.: Eur. J. Pharmacol., 591, 189 (2008),<br></p>Formula:C47H62N12O11S2Color and Shape:NeatMolecular weight:1035.20N-Methylformamide
CAS:Controlled Product<p>Applications N-Methylformamide is used in amidation or transamidation chemical reactions where formamide is insufficient.<br>References Rao, S. et al.: Org. Lett., 15, 1496 (2013); Xu, K. et al.: Chem. A. Eur. J., 18, 9793 (2012);<br></p>Formula:C2H5NOColor and Shape:NeatMolecular weight:59.07rac 7-Hydroxy Efavirenz
CAS:Controlled ProductFormula:C14H9ClF3NO3Color and Shape:NeatMolecular weight:331.674-Amino-N-pyridin-3-ylmethylbenzamide
CAS:Formula:C13H13N3OPurity:97%Color and Shape:SolidMolecular weight:227.2671-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,6-diol
CAS:Controlled Product<p>Applications 1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a degradation product of phenylephrine during the synthesis of the anti-cold medicine.<br>References Dousa, M. et al.: J. Pharm. Biomed. Anal., 55, 949 (2011);<br></p>Formula:C15H17NO4Color and Shape:NeatMolecular weight:275.301,3-Bis(4-nitrophenyl)urea
CAS:Controlled Product<p>Applications 1,3-Bis(4-nitrophenyl)urea is the active component of the antifertility agent nicarbazin, in chicken, duck, and goose plasma.<br>References Polin, D., et al.: Poultry Sci., 35, 1367 (1956), Primus, T.M., et al.: J. Agric. Food Chem., 49, 3589 (2001),<br></p>Formula:C13H10N4O5Color and Shape:Light Yellow To YellowMolecular weight:302.24Defluoro Paroxetine Hydrochloride
CAS:Controlled ProductFormula:C19H22ClNO3Color and Shape:NeatMolecular weight:347.84Morpholin-4-yl-acetic acid methyl ester hydrochloride
CAS:Purity:95.0%Color and Shape:Solid, No data available.Molecular weight:195.63999938964844Ethyl 7-chloro-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
CAS:Purity:95+%Molecular weight:334.73001098632812-(BIPHENYL-4-YL)-4-CHLORO-6-PHENYL-1,3,5-TRIAZINE
CAS:Purity:98.0%Molecular weight:343.80999755859375Defluoro Flunarizine Dihydrochloride
CAS:Controlled Product<p>Impurity Flumazenil EP Impurity B<br>Stability Hygroscopic<br>Applications Defluoro Flunarizine (Flumazenil EP Impurity B) Dihydrochloride, is an impurity of Flunarizine(F455200, Dihydrochloride), which is a calcium channel blocker. Flunarizine is a fluorinated derivative of Cinnarizine and a vasodilator (cerebral and peripheral).<br>References Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975), Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979), Nihard, P., et al.: Angiology, 33, 37 (1982), Holmes, B., et al.: Drugs, 27, 6 (1984)<br></p>Formula:C26H27FN2·2ClHColor and Shape:NeatMolecular weight:459.434-Methyl-2-(4-methyl-2-pyridinyl)-1-(2-oxo-2-phenylethyl)pyridinium bromide
Molecular weight:383.289001464843752-(2-(Pyridin-2-yl)-1H-indol-3-yl)ethanamine hydrochloride
CAS:Purity:95.0%Molecular weight:273.76000976562510-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine
CAS:Purity:95.0%Molecular weight:370.570007324218752-Ethoxybenzimidohydrazide Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 2-Ethoxybenzimidohydrazide Hydrochloride, is a derivative of Vardenafil (V098001), an erectile dysfunction (ED) drug and an inhibitor of phosphodiesterase type 5 (PDE-5) enzyme.<br>References Reddy, Vajrala Venkata., et al.: Synth. Commun., 42, 3513(2012)<br></p>Formula:C9H13N3O•HClColor and Shape:NeatMolecular weight:179.2236463-(4-Methoxy-phenyl)-1-phenyl-1 H -pyrazole-4-carbaldehyde
CAS:Purity:95.0%Molecular weight:278.31100463867195-(benzo[d]thiazol-2-yl)thiophene-2-carbonyl chloride
CAS:Purity:95.0%Molecular weight:279.7600097656252-(3-Methyl-pyrazol-1-yl)-propionic acid methyl ester
CAS:Formula:C8H12N2O2Color and Shape:LiquidMolecular weight:168.1962-(1-Hydroxyethyl) Promazine Sulfoxide (mixture of diastereomers)
CAS:<p>Applications A metabolite of Promazine (P756300).<br>References Dewey, E.A., et al.: Drug Metab. Dispos., 9, 30 (1981), Kronstrand, R., et al.: J. Anal. Toxicol., 27, 464 (2003),<br></p>Formula:C19H24N2O2SColor and Shape:NeatMolecular weight:344.474-methyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:255.339996337890623-(2-Cyanopropan-2-yl)-N-(3-((7-methoxyquinazolin-4-yl)amino)-4-methylphenyl)benzamide
CAS:Purity:97.0%Molecular weight:451.5299987792969Ref: 10-F544635
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquire4-CHLORO-2-(3-PYRIDYL)-QUINAZOLINE
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:241.679992675781254-Methyl-2-(1-methyl-piperidin-4-yl)-2H-pyrazol-3-ylamine
CAS:Formula:C10H18N4Purity:97%Color and Shape:SolidMolecular weight:194.282Teneligliptin
CAS:<p>Teneligliptin (MP-513), potent DPP-4 inhibitor, IC50 ~1 nM, blocks DPP-4 in human/rat plasma and recombinant forms.</p>Formula:C22H30N6OSPurity:99.73%Color and Shape:SolidMolecular weight:426.58[2-(1H-indol-3-yl)ethyl][(thiophen-2-yl)methyl]amine hydrochloride
CAS:Purity:95.0%Molecular weight:292.82998657226562-(4,6-Bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl)-5-(octyloxy)phenol
CAS:Purity:98%Molecular weight:509.6940002441406PD 169,316
CAS:<p>M02298 - PD 169,316</p>Formula:C20H13FN4O2Purity:>98%Color and Shape:SolidMolecular weight:360.34799194335942-(chloromethyl)-5-(5-methylthiophen-2-yl)-1H,4H-thieno[2,3-d]pyrimidin-4-one
CAS:Purity:95%Molecular weight:296.79000854492192-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)acetohydrazide
CAS:Purity:95.0%Molecular weight:253.610000610351566-fluoro-2-methylquinoline-4-carboxylic acid
CAS:Formula:C11H8FNO2Purity:95.0%Color and Shape:Yellow powderMolecular weight:205.1882-(piperazin-1-yl)quinazolin-4(3H)-one dihydrochloride
CAS:Purity:95.0%Molecular weight:303.190002441406254-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ol
CAS:Purity:97.0%Molecular weight:319.7200012207031Alfuzosin
CAS:<p>Alfuzosin (SL 77499) is an alpha-1 adrenergic antagonist used to treat benign prostatic hypertrophy and urethral dysfunction.</p>Formula:C19H27N5O4Purity:99.64%Color and Shape:White Crystaline PowderMolecular weight:389.454,4',5,5'-Tetra(pyridin-4-yl)-2,2'-bi(1,3-dithiolylidene)
CAS:Purity:98%Molecular weight:512.6799926757812Candoxatril
CAS:<p>Candoxatril is an inhibitor neutral endopeptidase (NEP).</p>Formula:C29H41NO7Purity:97.73% - 99.94%Color and Shape:SolidMolecular weight:515.646,7-Dimethyl-3-phenyl-quinoxaline-2-carboxylic acid ethyl ester
Purity:95.0%Molecular weight:306.364990234375Methyl 4-((6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)oxy)benzoate
CAS:Purity:97.0%Molecular weight:324.3399963378906(2E)-1-{[1,1'-biphenyl]-4-yl}-3-(thiophen-2-yl)prop-2-en-1-one
CAS:Purity:95.0%Molecular weight:290.38000488281255-(1,3-Dioxolan-2-yl)-2-(4-methoxybenzoyl)thiophene
CAS:Purity:97.0%Molecular weight:290.32998657226563-Amino-5-methylpyridin-2(1H)-one
CAS:Formula:C6H8N2OPurity:95.0%Color and Shape:SolidMolecular weight:124.143(5-Methyl-pyridin-2-yl)-thiourea
CAS:Formula:C7H9N3SPurity:95.0%Color and Shape:SolidMolecular weight:167.232-(4-chlorophenyl)-6-methylquinoline-4-carboxylic acid
CAS:Color and Shape:SolidMolecular weight:297.7399902343752-(3-Chloro-thiophen-2-yl)-1H-benzoimidazole-5-carboxylic acid
CAS:Color and Shape:SolidMolecular weight:278.70999145507812-(5-(Bromomethyl)pyridin-2-yl)isoindoline-1,3-dione
CAS:Purity:95.0%Molecular weight:317.14199829101563-(4-Bromo-pyrazol-1-yl)-propionic acid
CAS:Formula:C6H7BrN2O2Color and Shape:SolidMolecular weight:219.038
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