Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65941 products of "Quinazoline and Quinoline Derivatives"
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1-(5-Fluoropyridin-2-yl)-1,4-diazepane dihydrochloride
CAS:Purity:95.0%Molecular weight:268.16000366210943-Phenoxyphenylacetonitrile
CAS:Controlled Product<p>Applications 3-PHENOXYPHENYLACETONITRILE (cas# 51632-29-2) is a useful research chemical.<br></p>Formula:C14H11NOColor and Shape:NeatMolecular weight:209.242-[5-(3-bromophenyl)-1H-pyrazol-3-yl]-5-methylphenol
CAS:Purity:95.0%Molecular weight:329.1969909667969(S)-4,5,6,7-Tetrahydro-N2,N6-propionyl-2,6-benzothiazolediamine
CAS:Controlled Product<p>Applications Pramipexole derivative.<br></p>Formula:C13H19N3O2SColor and Shape:NeatMolecular weight:281.37rac-cis-Ambroxol
CAS:Controlled Product<p>Impurity Ambroxol EP Impurity D<br>Applications cis-Ambroxol is the cis-isomeric impurity of Ambroxol (A575905). cis-Ambroxol is a metabolite Bromhexine (B678600). Ambroxol EP Impurity D<br>References Liu, J. et al.: J. Pharmac. Biomed. Anal., 51, 1134 (2010); Schmid, J.: J. Chrom. Biomed. Appl., 414, 65 (1987);<br></p>Formula:C13H18Br2N2OColor and Shape:NeatMolecular weight:378.10(S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester
CAS:Controlled ProductFormula:C15H13F2NO4Color and Shape:Off-White To Light YellowMolecular weight:309.26(E)-N-Methylcinnamylamine Hydrochloride
CAS:Controlled Product<p>Applications (E)-N-Methylcinnamylamine is an 3-amino-1-phenyl-prop-1-ene derivative with potential to inhibit and inactivate monoamine oxidase.<br>References Williams, C.H. et al.: Biochim. Biophys. Acta Prot. Struc. Mol. Enzymol., 119, 111 (1992);<br></p>Formula:C10H14ClNColor and Shape:NeatMolecular weight:183.682-(1-Hydroxyethyl) Promazine Sulfoxide (mixture of diastereomers)
CAS:<p>Applications A metabolite of Promazine (P756300).<br>References Dewey, E.A., et al.: Drug Metab. Dispos., 9, 30 (1981), Kronstrand, R., et al.: J. Anal. Toxicol., 27, 464 (2003),<br></p>Formula:C19H24N2O2SColor and Shape:NeatMolecular weight:344.472-Chloro-5-(5-Chloro-2-thienyl)pyridine
CAS:Formula:C9H5Cl2NSPurity:97.0%Color and Shape:SolidMolecular weight:230.113-(2-Cyanopropan-2-yl)-N-(3-((7-methoxyquinazolin-4-yl)amino)-4-methylphenyl)benzamide
CAS:Purity:97.0%Molecular weight:451.5299987792969Ref: 10-F544635
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquire3-(3,5-Dimethyl-pyrazol-1-ylmethyl)-phenylamine
CAS:Formula:C12H15N3Purity:98%Color and Shape:Low Melting SolidMolecular weight:201.2734-Methyl-2-(1-methyl-piperidin-4-yl)-2H-pyrazol-3-ylamine
CAS:Formula:C10H18N4Purity:97%Color and Shape:SolidMolecular weight:194.2824-(5-azetidin-3-yl-1,2,4-oxadiazol-3-yl)pyridine dihydrochloride
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:275.13000488281255-(Benzyloxy)-1-(2,2-dimethoxyethyl)-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
CAS:Purity:97.0%Molecular weight:391.37600708007812-(4,6-Bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl)-5-(octyloxy)phenol
CAS:Purity:98%Molecular weight:509.69400024414062-(3,5-dicyclopropyl-1H-pyrazol-1-yl)ethan-1-amine
CAS:Purity:95.0%Molecular weight:191.2779998779297N-(3-pyridinylmethyl)-1,2,3,4-tetrahydro-1-naphthalenamine hydrobromide
CAS:Purity:95.0%Molecular weight:319.24600219726562-((2R,3R)-3-(tert-butyl)-4-methoxy-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine
CAS:Purity:95%,99%eeMolecular weight:301.32598876953125(R)-Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity D<br>Applications (R)-Rivastigmine (Rivastigmine EP Impurity D) is a carbamate inhibitor of acetylcholinesterase used as a treatment of Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lucangioli, S. E., et al.: J. Chromatogr. A, 1081, 31-35 (2005); Bar-On, P., et al.: Biochem., 41, 3555-3564 (2002);<br></p>Formula:C14H22N2O2·C4H6O6Color and Shape:NeatMolecular weight:400.42(2S,2'S)-1,1'-[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)imino]bis(1-oxo-2,1-ethanediyl)]bis-2-pyrrolidinecarbonitrile
CAS:Formula:C24H33N5O3Color and Shape:Off-WhiteMolecular weight:439.55Safinamide Mesylate
CAS:Controlled Product<p>Applications Safinamide mesylate is a potent and selective MAO-B inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C17H19FN2O2·CH4O3SColor and Shape:White To Off-WhiteMolecular weight:398.45Telmisartan-d3
CAS:Controlled ProductFormula:C332H3H27N4O2Color and Shape:BeigeMolecular weight:517.64Lansoprazole Sulfone-d4
CAS:Controlled ProductFormula:C16H10D4F3N3O3SColor and Shape:NeatMolecular weight:389.381,2:4,5-bis-O-(1-Methylethylidene)-β-D-Fructopyranose
CAS:Controlled Product<p>Applications 1,2:4,5-bis-O-(1-Methylethylidene)-β-D-Fructopyranose is a reagent in the synthesis of antibacterial/antifungal monosaccaride esters. Also used in the synthesis of antihyperlipidemic novel compounds involving glycosyl fructose derivatives.<br>References Shen, Y. et al.: Molecules, 17, 8661 (2012); Tiwari, P. et al.: Bioorg. Med. Chem. Lett., 16, 6028 (2006);<br></p>Formula:C12H20O6Color and Shape:NeatMolecular weight:260.283,6-Bis(5-bromothiophen-2-yl)-2,5-dioctylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione
CAS:Purity:95%Molecular weight:682.57000732421882-(4-Chlorophenoxy)aniline
CAS:Controlled Product<p>Applications Amoxapine impurity.<br>References Matsuo, M., et al.: Chem. Pharma. Bull., 33, 4409 (1985),<br></p>Formula:C12H10ClNOColor and Shape:NeatMolecular weight:219.678-Hydroxy Amoxapine
CAS:<p>Applications A metabolite of Amoxapine.<br>References Hansen, E., et al.: Drug Metab. Dispos.,15, 97 (1987), Hansen, E., et al.: Xenobiotica, 25, 1081 (1995), Moody, J., et al.: Drug Metab. Dispos., 27, 1157 (1999),<br></p>Formula:C17H16ClN3O2·ClHColor and Shape:NeatMolecular weight:366.242-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid
CAS:Purity:97%Molecular weight:313.739990234375Nilotinib Regio Isomer
CAS:Controlled Product<p>Applications Nilotinib Regio Isomer is a more potent Bcr-Abl tyrosine kinase inhibitor for the treatment of patients with myelogenous leukemia. It is a COVID19-related research product.<br>References Wei-Sheng H., et al.: Synthesis, 14, 2121 (2007); Bilbe, G.,et al.: From PCT Int. Appl. (2005), WO 2005039586 A1 20050506<br></p>Formula:C28H22F3N7OColor and Shape:NeatMolecular weight:529.52Diazoxide
CAS:Controlled Product<p>Applications Diazoxide reduces status epilepticus neuron damage in diabetes. A potassium channel opener<br>References Baba, A., et al.: J. Neurosci., 23, 7737 (2003), Bancila, V., et al.: J. Neurochem., 90, 1243 (2004), Bancila, V., et al.: J. Biol. Chem., 280, 8793 (2005),<br></p>Formula:C8H7ClN2O2SColor and Shape:NeatMolecular weight:230.672-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine, Hydrochloride
CAS:Controlled ProductFormula:C9H9ClF3NO·ClHColor and Shape:NeatMolecular weight:276.08N-Desmethyl Sildenafil Hemicitrate
CAS:Controlled Product<p>Applications N-Desmethyl Sildenafil Hemicitrate is an impurity of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.<br>References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996); Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998)<br></p>Formula:C48H64N12O15S2Color and Shape:NeatMolecular weight:1113.22Sulindac Sulfone-d6
CAS:Controlled Product<p>Applications Labelled analogue of Sulindac Sulfone, an active metabolite of Sulindac. Inducer of apoptosis independent of cyclooxygenase inhibition. Inhibits cell growth by inducing apoptosis.<br>References Piazza, G.A. et al.: Cancer Res., 55, 3310 (1995);<br></p>Formula:C20H11D6FO4SColor and Shape:NeatMolecular weight:378.45N-Cyano-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-carbamimidic Acid Methyl Ester
CAS:Controlled Product<p>Impurity Cimetidine EP Impurity B<br>Applications N-Cyano-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-carbamimidic Acid Methyl Ester which is an impurity of Cimetidine (C441650), which acts as a competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output (1).<br>References 1. Brimblecombe, R. et al.: J. Int. Med. Res. 1975 Mar:3(2) 86-92<br></p>Formula:C10H15N5OSColor and Shape:White To Off-WhiteMolecular weight:253.32Aripiprazole
CAS:Controlled Product<p>Applications Aripiprazole is an agonist at the dopamine autoreceptor and an antagonist at the postsynaptic D2 receptor (1,2,3,4). Aripiprazole is an antipsychotic and a potential drug candidate for treating psychoses such as schizophrenia.<br>References (1) Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998)(2) Shiokawa, M., et al.: Eur.J.Pharmacol. 570, 108 (2007)(3) Oshiro, Y., et al.: J. Med. Chem. 41, 658 (1998)(4) Ozdemir, V., et al.: Curr Opin Investig Drugs. 3, 113 (2002)<br></p>Formula:C23H27Cl2N3O2Color and Shape:NeatMolecular weight:448.391-(3-Hydroxypropyl)theobromine
CAS:Controlled ProductFormula:C10H14N4O3Color and Shape:White To Off-WhiteMolecular weight:238.243Nimodipine-d7
CAS:Controlled Product<p>Applications A labelled dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral).<br>References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),<br></p>Formula:C21H19D7N2O7Color and Shape:NeatMolecular weight:425.48Deacetyl Ketoconazole
CAS:Controlled Product<p>Impurity Ketoconazole EP Impurity D<br>Applications Deacetyl Ketoconazole (Ketoconazole EP Impurity D) is a Ketoconazole derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C24H26Cl2N4O3Color and Shape:Off-WhiteMolecular weight:489.391-Methoxy Empagliflozin
CAS:Controlled Product<p>Applications 1-Methoxy Empagliflozin is an impurity in the synthesis of Empagliflozin drug (E521510), which is potent and selective inhibitor of sodium glucose co-transporter-2 (SGLT-2).<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Formula:C24H29ClO8Color and Shape:White To Off-WhiteMolecular weight:480.943-(9H-Carbazol-4-yloxy)-1,2-propanediol
CAS:Controlled Product<p>Applications 3-(9H-Carbazol-4-yloxy)-1,2-propanediol is used in the synthesis of carvedilol, a β-adrenergic blocking agent.<br>References Naidu, K. et al.: Org. Chem. An Indian J., 6, 171 (2010);<br></p>Formula:C15H15NO3Color and Shape:NeatMolecular weight:257.28Amisulpride
CAS:Controlled Product<p>Applications Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985), Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997),<br></p>Formula:C17H27N3O4SColor and Shape:WhiteMolecular weight:369.48N-Nitroso Quinapril
CAS:Controlled ProductFormula:C25H29N3O6Color and Shape:NeatMolecular weight:467.517-Hydroxy Chlorpromazine-d6 Hydrochloride
CAS:Controlled Product<p>Applications Labelled analogue of 7-Hydroxychlorpromazine, the 7-hydroxy analogue and a major metabolite of the atypical antipsychotic Chlorpromazine (C424750).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jori, A. et al.: Int. J. Neuropharmacol., 5, 435 (1966); Shavit, S. et al.: Comm. Psychopharmacol., 4, 495 (1980);<br></p>Formula:C17H14D6Cl2N2OSColor and Shape:NeatMolecular weight:377.36Empagliflozin Methyl Acetate
CAS:<p>Applications Empagliflozin Methyl Acetate is an impurity of Empagliflozin (E521510), which is a novel, potent and selective SGLT-2 inhibitor. It improves glycaemic control syndrome in diabetic rats.<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Formula:C25H29ClO8Color and Shape:White To Off-WhiteMolecular weight:492.95Desethylcarbamoyl Cabergoline
CAS:Controlled Product<p>Impurity Cabergoline EP Impurity D<br>Applications A metabolite of Cabergoline, having affinity for D1 and D2 dopamine receptors in rat striatum<br>References Battaglia, R., et al.: Xenobiotica, 23, 1377 (1993), Miyagi, M., et al.: Biol. Pharm. Bull., 19, 1210 (1996),<br></p>Formula:C23H32N4OColor and Shape:Beige SolidMolecular weight:380.53Praziquantel-d11
CAS:Controlled Product<p>Applications Labelled Praziquantel (P702095). Anthelmintic, effective against flatworms.<br>References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 (2010), Wang, W., et al.: Parasitol., 137, 1905 (2010),<br></p>Formula:C192H11H13N2O2Color and Shape:White To Light BeigeMolecular weight:323.47Dehydro Ivabradine
CAS:Controlled ProductFormula:C27H34N2O5Color and Shape:Light Yellow To Dark BrownMolecular weight:466.576-Methoxy-2-naphthoic Acid
CAS:Controlled Product<p>Impurity Naproxen USP Related Compound A<br>Applications An impurity of Naproxen (N377525) with bactericidal and fungicidal activity. A metabolite of Nabumetone (N200500). Naproxen USP Related Compound A.<br>References Khorana, M.L. et al.: J. Pharmac. Sci., 56, 993 (1967); Ray, J.E. et al.: J. Chrom. Biomed. Appl., 336, 234 (1984);<br></p>Formula:C12H10O3Color and Shape:Off-WhiteMolecular weight:202.21(S)-Naproxen Methyl Ester
CAS:<p>Impurity Naproxen EP Impurity E<br>Applications Naproxen (N377520) methyl derivative. Naproxen impurity. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) indicated for the treatment of pain, inflammatory conditions such as rheumatoid arthritis, and fever. The drug belongs to the 2-aryl propionic acid family of COX-1 and COX-2 inhibitors.<br>References Haddock, R., et al.: Xenobiotica, 14, 327 (1984), Jeremy, J., et al.: Drugs, 40, 53 (1990), Wadhwa, L., et al.: Int. J. Pharm., 118, 31 (1995),<br></p>Formula:C15H16O3Color and Shape:NeatMolecular weight:244.29Vadadustat
CAS:<p>Applications Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.<br>References Pergola, P., et al.: Kidney Int., 90, 1115 (2016);<br></p>Formula:C14H11ClN2O4Color and Shape:BeigeMolecular weight:306.703-Dehydroxy Salbutamol
CAS:Controlled Product<p>Impurity Levalbuterol USP Related Compound B; Salbutamol EP Impurity C<br>Applications 3-Dehydroxy Salbutamol (Levalbuterol USP Related Compound B; Salbutamol EP Impurity C) is an isoprenaline based selective stimulants of β-adrenergic receptors in bronchial muscles.<br>References Hartley, D., et al.: Nature., 219, 5156 (1968);<br></p>Formula:C13H21NO2Color and Shape:NeatMolecular weight:223.313-Ethyl-2-imine Meloxicam
CAS:Controlled Product<p>Applications Meloxicam (M216100) impurity.<br></p>Formula:C16H17N3O4S2Color and Shape:Light YellowMolecular weight:379.45Oxcarbazepine-D4 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant.Only available as a mixture of deuterated material:d-1: 1%d-2: 9%d-3: 35%d-4: 55%<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989), Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001),<br></p>Formula:C152H4H8N2O2Color and Shape:Light Orange Colour PowderMolecular weight:256.291-Amino-3-adamantanol
CAS:Controlled Product<p>Applications Reagent used in the preparation of Vildagliptin.<br>References Fukushima, H., et al.: Bioorg. Med. Chem., 16, 4093 (2008), Anand, R., et al.: J. Med. Chem., 52, 1602 (2009),<br></p>Formula:C10H17NOColor and Shape:NeatMolecular weight:167.25Iloperidone-d3
CAS:Controlled Product<p>Applications Labelled Iloperidone. Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sainati, S.M., et al.: J. Clin. Pharmacol., 35, 713 (1995), Szewczak, M.R., et al.: J. Pharmacol. Exp. Ther., 274, 1404 (1995), Kongsamut, S., et al.: Eur. J. Pharmacol., 317, 417 (1996)<br></p>Formula:C24H24D3FN2O4Color and Shape:Light YellowMolecular weight:429.5Carisoprodol-d3
CAS:Controlled Product<p>Applications Muscle relaxant (skeletal).<br>References Musso, D., et al.: J. Med. Chem. 46, 399 (2003), Newman, P., et al.: Eur. J. Clin. Pharm., 23, 31 (1982).<br></p>Formula:C122H3H21N2O4Color and Shape:White PowderMolecular weight:263.35O-Methyl Meloxicam
CAS:<p>Applications O-Methyl Meloxicam is an impurity of Meloxicam (M216100).<br></p>Formula:C15H15N3O4S2Color and Shape:NeatMolecular weight:365.43(S)-Ketamine Hydrochloride
CAS:Controlled Product<p>Applications (S)-Ketamine is the more active enantiomer of the NMDA receptor antagonist and anesthetic agent Ketamine (K165300). Controlled Substance.<br>References Meliska, C.J. et al.: J. Pharmacol Exp. Therap., 212, 206 (1980); Smith, D.J. et al.: Neuropharmacology, 20, 391 (1981); Klockgether-Radke, A.P. et al.: Eur. J. Anaesthesiol., 22, 215 (2005);<br></p>Formula:C13H16ClNO·ClHColor and Shape:Off-WhiteMolecular weight:274.1862Felodipine-13C4, d3
CAS:Controlled Product<p>Applications Felodipine-13C4, d3 is the labeled analogue of Felodipine (F232375), a dihydropyridine calcium channel blocker.<br>References Berntsson, P.B., et al.: Acta Pharm. Suec., 18, 221 (1981); Kratochwil, N., et al.: Biochem. Pharmacol., 64, 1355 (2002); O'Brien, S., et al.: J. Med. Chem., 48, 1287 (2005); Castilho, M., et al.: Bioorg. Med. Chem., 14, 516 (2006)<br></p>Formula:C1413C4H16D3Cl2NO4Color and Shape:NeatMolecular weight:391.24Dipyridamole
CAS:Controlled Product<p>Applications Selective inhibitor of phosphodiesterase V (PDE 5); potent coronary vasodilator drug; adenosine transport inhibitor; inhibitor of platelet aggregation.<br>References Buchalter, M.B., et al.: Postgrad. Med. J., 66, 531 (1990), Sundaram, M., et al.: J. Biol. Chem., 273, 21519 (1998), Denis, D., et al.: Eur. J. Pharmacol., 367, 343 (1999),<br></p>Formula:C24H40N8O4Color and Shape:YellowMolecular weight:504.632-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine Dihydrochloride
CAS:Controlled Product<p>Applications 2-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine Dihydrochloride is an impurity of Chlorpromazine (C424750), which is used as an antiemetic; antipsychotic. 2-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine is also used in the synthesis of novel phenothiazine compounds with antimalarial activity.<br>References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970); Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990); Kalkanidis, M., et. al.: Biochem. Pharmacol., 63, 833 (2002)<br></p>Formula:C21H28ClN3S•2HClColor and Shape:NeatMolecular weight:462.912-Mercapto-N-methyl-benzamide
CAS:Controlled Product<p>Stability Air Sensitive<br>Applications 2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib (A794650) which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.<br>References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),<br></p>Formula:C8H9NOSColor and Shape:BeigeMolecular weight:167.228(2,6-Dichloro-phenyl)guanidine
CAS:Controlled ProductFormula:C7H7Cl2N3Color and Shape:NeatMolecular weight:204.0574-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
CAS:Controlled Product<p>Applications Sitagliptin intermediate.<br>References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982), Cameron, M., et al.: J. Pharm. Biomed. Anal., 28, 137 (2002),<br></p>Formula:C16H12F6N4O2Color and Shape:NeatMolecular weight:406.28Nitrofurantoin-13C3
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A nitrofuran labelled antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976), Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004),<br></p>Formula:C3C5H6N4O5Color and Shape:NeatMolecular weight:241.14Apixaban-d3
CAS:Controlled Product<p>Applications Apixaban-d3 is labelled Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Formula:C25H22D3N5O4Color and Shape:White To Off-WhiteMolecular weight:462.521,5-Dihydroxyempagliflozin
CAS:Controlled ProductFormula:C23H29ClO8Color and Shape:NeatMolecular weight:468.92Norketamine-d4
CAS:Controlled Product<p>Applications A labelled metabolite of Ketamine (K165300).<br>References Sullivan, H., et al.: J. Med. Chem., 16, 909 (1973), Moreton, J., et al.: J. Pharmacol. Exp. Ther., 203, 303 (1977), Lin, H., et al.: J. Food Drug Anal., 13, 107 (2005),<br></p>Formula:C12H10D4ClNOColor and Shape:NeatMolecular weight:227.722-Phenylbutyric Acid
CAS:Controlled ProductFormula:C10H12O2Color and Shape:White To Off-WhiteMolecular weight:164.2Saquinavir Mesylate
CAS:Controlled Product<p>Applications A selective HIV protease inhibitor. Antiviral.<br>References Roberts, N.A., et al.: Science, 248, 358 (1990), Craig, J.C., et al.: Antiviral Res., 16, 295 (1991),<br></p>Formula:C38H50N6O5·CH4O3SColor and Shape:NeatMolecular weight:766.95N-Nitroso Lisinopril
CAS:Formula:C21H30N4O6Color and Shape:White To Light YellowMolecular weight:434.486N,N-Dimethyl-4-hydroxymethoxy Clomiphene (~90%, contains ~10% Z-isomer)
CAS:Controlled ProductFormula:C25H26ClNO3Color and Shape:NeatMolecular weight:423.93Mitotane
CAS:Controlled Product<p>Applications An Antineoplastic. Used as an adrenolytic agent.<br>References Das, S., and Thomas, P.: Endocrinology, 140, 1953 (1999), Andersen, A., et al.: Ther. Drug. Monit., 21, 355 (1999), Leblond, V.S., and Hontela, T.: Toxicol. Appl. Pharmacol., 157, 16 (1999)<br></p>Formula:C14H10Cl4Color and Shape:White To Off-WhiteMolecular weight:320.047-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
CAS:Controlled Product<p>Applications Gefitinib intermediate.<br>References Kelly, L., et al.: Cancer Cell., 1, 421 (2002), Pandey, A., et al.: J. Med. Chem., 45, 3772 (2002), Ciardiello, F., et al.: Exp. Opin Emerg. Drugs, 8, 501 (2003), Caponigro, F., et al.: Curr. Opin Oncol., 16, 225 (2004),<br></p>Formula:C16H21N3O4Color and Shape:NeatMolecular weight:319.366-Hexadecanoylamino-4-methylumbelliferyl β-D-Galactopyranoside
CAS:Formula:C32H49NO9Color and Shape:NeatMolecular weight:591.734-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole Dihydrochloride
CAS:Controlled ProductFormula:C7H13N3S·2ClHColor and Shape:NeatMolecular weight:244.19Levosimendan Cyanoacetate Hydrazone Impurity
Controlled Product<p>Applications Levosimendan Cyanoacetate Hydrazone is an impurity of Levosimendan (L378000); a positive inotropic agent with vasodilating activity. Also cardiotonic.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)<br></p>Formula:C16H17N5O3Color and Shape:NeatMolecular weight:327.34Phenylbutazone
CAS:Controlled Product<p>Applications A non-steroidal anti-inflammatory compound. An inhibitor of cyclooxygenase that is also a substrate for peroxidation by cyclooxygenase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ali, S.L., Anal. Profiles Drug Subs., 11, 483 (1982), Hughes, M.F., et al.: Mol. Pharmacol., 34, 186 (1988),<br></p>Formula:C19H20N2O2Color and Shape:White To Off-WhiteMolecular weight:308.372,6-Dimethylaniline-d6
CAS:Controlled Product<p>Applications Labelled Bupivacaine (B689560) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lepage, F., et al.: Eur. J. Med. Chem., 27, 581 (1992), Thummel, K.E., et al.: Drug Metab. Dispos., 21, 350 (1993)<br></p>Formula:C82H6H5NColor and Shape:BrownMolecular weight:127.22rac N-Propyl-2-cyanimidopyrrolidine-5-acetic Acid
CAS:Controlled Product<p>Applications rac N-Propyl-2-cyanimidopyrrolidine-5-acetic Acid is a potent peptidic renin inhibitor. Pramipexole Related Compound<br></p>Formula:C10H15N3O2Color and Shape:NeatMolecular weight:209.24Lansoprazole-d4
CAS:Controlled ProductFormula:C162H4H10F3N3O2SColor and Shape:NeatMolecular weight:373.39Dipyridamole Tri(diethanolamine)
CAS:Controlled Product<p>Impurity Dipyridamole EP Impurity B<br>Applications Dipyridamole Tri(diethanolamine) (Dipyridamole EP Impurity B) Dipyridamole (D492625) impurity.<br>References Gerlach, E., et al.: Arzneim.-Forsch., 15, 558 (1965),<br></p>Formula:C23H40N8O6Color and Shape:NeatMolecular weight:524.61Sulindac Sulfide
CAS:<p>Stability Hygroscopic<br>Applications An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP.<br>References Hermann, C., et al.: Oncogene, 17, 1769 (1998), Lim, T.J., et al.: Biochem. Pharmacol., 58, 1097 (1999), Zhang, Z. and DuBois, R.N.: Gastroenterology, 118, 1012 (2000),<br></p>Formula:C20H17FO2SColor and Shape:Yellow-OrangeMolecular weight:340.41(R,S)(S,R)-Benidipine Hydrochloride
CAS:Formula:C28H31N3O6·HClColor and Shape:NeatMolecular weight:542.023exo-Granisetron
CAS:<p>Impurity Granisetron EP Impurity F<br>Applications Granisetron Impurity F. Granisetron EP Impurity F.<br>References Fozard, J. R., et al.: Br. J. Pharmacol., 61, 130 (1977), Bradley, P.B., et al.: Neuropharmacology, 25, 563 (1986),<br></p>Formula:C18H24N4OColor and Shape:NeatMolecular weight:312.41rac,trans-Milnacipran Hydrochloride
CAS:Controlled Product<p>Applications rac,trans-Milnacipran Hydrochloride is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moret, C., et al.: Neuropharmacology, 24, 1211 (1985), Palmier, C., et al.: Eur. J. Clin. Pharmacol., 37, 235 (1989), Spencer, C.M., et al.: Drugs, 56, 405 (1998)<br></p>Formula:C15H23ClN2OColor and Shape:NeatMolecular weight:282.81cis-Hydroxy Praziquantel
CAS:<p>Applications The main cis-monohydroxylated metabolite of Praziquantel (P702095).<br>References Buehring, K., et al.: Eur. J. Drug Metab. Pharm., 3, 179 (1978), Moldeus, P., et al.: Methods Enzymol., 52, 60 (1978), Cioli, D., et al.: Pharmacol. Ther., 68, 35 (1995),<br></p>Formula:C19H24N2O3Color and Shape:NeatMolecular weight:328.404-Hydroxy Moxonidine
CAS:Controlled ProductFormula:C9H13N5O2Color and Shape:NeatMolecular weight:223.23
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