Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65576 products of "Quinazoline and Quinoline Derivatives"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Des(R)-3-Aminopiperidine Linagliptin
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 7-(2-Butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione is an impurity of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Formula:C20H18N6O2Color and Shape:NeatMolecular weight:374.4(3’S,3R,4S)-Desfluoro Ezetimibe
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications (3’S,3R,4S)-Desfluoro Ezetimibe is an impurity of the cholesterol absorption inhibitor Ezetimibe (E975000).<br>References Gajjar, A.K., Open. Con. Proceed. J., 2, 108 (2011);<br></p>Formula:C24H22FNO3Color and Shape:NeatMolecular weight:391.434-Fluorobenzoic acid
CAS:Controlled Product<p>Applications 4-Fluorobenzoic acid<br></p>Formula:C7H5FO2Color and Shape:NeatMolecular weight:140.11Ethyl 3-(4-Bromophenyl)-1-methyl1H-pyrazole-5-carboxylate
CAS:Formula:C13H13BrN2O2Purity:95.0%Color and Shape:SolidMolecular weight:309.163Tazarotenic Acid Sulfoxide
CAS:Controlled Product<p>Applications Tazarotenic Acid Sulfoxide is the inactive sulfoxide metabolite of Tazarotenic Acid (T010060).<br>References Cashman, J., et al.: Chem. Res. Toxicol., 8, 166 (1995), Mugford, C., et al.: Drug Metab. Rev., 30, 441 (1998), Marill, J., et al.: Biochem. Pharmacol., 63, 933 (2002),<br></p>Formula:C19H17NO3SColor and Shape:NeatMolecular weight:339.41Acetamiprid
CAS:Controlled Product<p>Applications A novel neonicotinid insecticide against Holotrichia consanguinea in sugarcane. Reports show that when exposed to neonicotinid pesticides honeybees have problems returnibg home after foraging and bumblebee colonies grow poorly and produce fewer queens. Used in Pesticide detection. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Srivastava, A., et al.: Indian Sugar, 32, 673 (1983), Fleming, R., et al.: J. Econ. Entomol., 78, 1179 (1985), Rao, Ch.V., et al.: Pestology, 35, 47 (2011), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:C10H11ClN4Color and Shape:Colourless To WhiteMolecular weight:222.677-Methoxy-1-naphthaleneethanamine Hydrochloride
CAS:Controlled ProductFormula:C13H15NO·ClHColor and Shape:NeatMolecular weight:237.73Elvitegravir
CAS:Controlled Product<p>Applications A novel inhibitor of human immunodeficiency virus type 1 integrase.<br>References Chou, T., et al.: Eur. J. Biochem., 115, 207 (1981), Baba, M., et al.: Antimicrob. Agents Chemother., 31, 1613 (1987), Craigie, R., et al.: J. Biol. Chem., 276, 23213 (2001), Chen, X., et al.: J. Mol. Biol., 380, 504 (2008),<br></p>Formula:C23H23ClFNO5Color and Shape:NeatMolecular weight:447.88Oxyphenbutazone
CAS:<p>Applications Anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yoshida, F., et al.: J. Med. Chem., 43, 2575 (2000), Chen, M., ET AL.: Pharm. Res., 18, 1645 (2001), Davis, A., et al.: Curr. Opin. Chem. Biol., 8, 378 (2004), Wang, J., ET AL.: Anal. Chim. Acta, 601, 156 (2007),<br></p>Formula:C19H20N2O3Color and Shape:NeatMolecular weight:324.37Loxapine N-Oxide
CAS:<p>Stability Hygroscopic, Light Sensitive<br>Applications Loxapine N-Oxide is a metabolite of Loxapine (L472750), a D2/D4-Dopamine receptor antagonist. It is a serotonergic receptor antagonist that acts as a dibenzoxazepine antipsychotic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shen, Y., et al.: J. Biol. Chem., 268, 18200 (1993), Fiorella, D., et al.: Psychopharmacology, 121, 347 (1995), Glusa, E., et al.: Br. J. Pharmacol., 130, 692 (2000)<br></p>Formula:C18H18ClN3O2Color and Shape:NeatMolecular weight:343.813-Chloro-N-methylpropan-1-amine Hydrochloride
CAS:Controlled Product<p>Applications 3-Chloro-N-methylpropan-1-amine Hydrochloride can be used as reactant/reagent in oxidative metabolism of ferrocene analogs of tamoxifen: characterization and antiproliferative activities of metabolites.<br>References Richard, M. A., et al.: ChemMedChem, 10, 981-990 (2015)<br></p>Formula:C4H10ClN•(HCl)Color and Shape:NeatMolecular weight:107.58364611-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
CAS:Controlled ProductFormula:C15H14N4O2Color and Shape:NeatMolecular weight:282.37-Hydroxy Chlorpromazine Hydrochloride
CAS:<p>Impurity Chlorpromazine 7-Hydroxy Impurity<br>Stability Hygroscopic<br>Applications 7-Hydroxychlorpromazine is the 7-hydroxy analogue and a major metabolite of the atypical antipsychotic Chlorpromazine (C424750).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jori, A. et al.: Int. J. Neuropharmacol., 5, 435 (1966); Shavit, S. et al.: Comm. Psychopharmacol., 4, 495 (1980);<br></p>Formula:C17H19ClN2OS·HClColor and Shape:White To Light PurpleMolecular weight:371.32Ranitidine
CAS:<p>Applications Ranitidine (cas# 66357-35-5) was used as a standard for testing the therapeutic effect of brown propolis extract against aspirin and ethanol- induced gastric ulcers.<br>References Patil, M., et al.: Eur. J. Biomed. Pharma. Sci., 7, 620 (2020)<br></p>Formula:C13H22N4O3SColor and Shape:NeatMolecular weight:314.40Levetiracetam Carboxylic Acid
CAS:Controlled ProductFormula:C8H13NO3Color and Shape:White To Off-WhiteMolecular weight:171.19Indazole-3-carboxylic Acid
CAS:Controlled Product<p>Applications Indazole-3-carboxylic Acid is an indole derivatives useful in treatment of pain and inflammation.<br>References Khanna P., et al.: Biochemistry, 40, 1441 (2001);<br></p>Formula:C8H6N2O2Color and Shape:NeatMolecular weight:162.145Quinoxyfen
CAS:Controlled Product<p>Applications Agricultural fungicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Corrales, M., et al.: Food Chem. Toxicol., 48, 3471 (2010), Lagunas-Allue, L., et al.: Anal. Bioanal. Chem., 398, 1509 (2010), Wong, J., et al.: J. Agric. Food Chem., 58, 5897 (2010),<br></p>Formula:C15H8Cl2FNOColor and Shape:Off-WhiteMolecular weight:308.135-Aminothiophene-2-carbonitrile
CAS:Formula:C5H4N2SPurity:98%Color and Shape:SolidMolecular weight:124.16Propoxyphenyl Thioaildenafil
CAS:Controlled Product<p>Applications Propoxyphenyl Thioaildenafil is an analogue of Thioaildenafil (T344365). Propoxyphenyl Thioaildenafil is a phosphodiesterase-5 inhibitor (PDE-5) that has been found in health supplements.<br>References Kee, C., Ge, X., Koh, H., Low, M.: J. Pharmaceut. Biomed., 70, 265 (2012)<br></p>Formula:C24H34N6O3S2Color and Shape:NeatMolecular weight:518.7Apixaban Dimer
CAS:Controlled Product<p>Applications Apixaban Dimer is an impurity compound of Apixaban (A726700). Apixaban is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful in the prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J. M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Formula:C40H34N10O6Color and Shape:NeatMolecular weight:750.78N-Nitroso-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-L-valine Methyl Ester-d8
Formula:C20H13D8N3O3Color and Shape:NeatHydroxy Nefazodone Dihydrochloride
CAS:Controlled Product<p>Applications A metabolite of Nefazodone (N389100), an antidepressant.<br>References Barbhaiya, R., et al.: Eur. J. Clin. Pharmacol., 49, 221 (1995), Greene, D., et al.: Clin. Pharmacokinet., 33, 260 (1997), Kalgutkar, A., et al.: Drug Metab. Dispos., 33, 243 (2005),<br></p>Formula:C25H34Cl3N5O3Color and Shape:NeatMolecular weight:558.93[3-[[[2-(Diaminomethyleneamino)-4-thiazolyl]methyl]thio]propionyl]sulfamide Hydrochloride
CAS:Controlled Product<p>Impurity Famotidine EP Impurity C<br>Applications An intermediate in the synthesis of the metabolite of the drug Famotidine.<br>References Yanagisawa, I., et al.: J. Med. Chem., 30, 1787 (1987), Singh, S., et al.: J. Pharm. Sci., 91, 253 (2002),<br></p>Formula:C8H14N6O3S3·ClHColor and Shape:Off-WhiteMolecular weight:374.89Ondansetron Hydrochloride Dihydrate
CAS:Formula:C18H19N3O·ClH·2H2OColor and Shape:Off-WhiteMolecular weight:365.852,5-Bis(2,2,2-trifluoroethoxy)benzoic Acid
CAS:Controlled Product<p>Impurity Flecainide EP Impurity D<br>Applications Flecainide Acetate Impurity D.<br>References Banitt, E., et al.: J. Med. Chem., 18, 1130 (1975),<br></p>Formula:C11H8F6O4Color and Shape:White To Off-WhiteMolecular weight:318.172,7-Bis(pyridin-4-ylmethyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone
CAS:Purity:95%Molecular weight:448.43798828125N-Nitrosocarvedilol
CAS:Controlled ProductFormula:C24H25N3O5Color and Shape:NeatMolecular weight:435.472trans-4-Aminocyclohexanol
CAS:<p>Applications trans-4-Aminocyclohexanol, used in the preparation of potential hypertensive agents and other biologically active compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chan, K.L. et al.: As. J. Pharmacol. Sci., 1, 91 (1979);<br></p>Formula:C6H13NOColor and Shape:NeatMolecular weight:115.174Deshydroxy Bicalutamide
CAS:Controlled Product<p>Impurity Bicalutamide EP Impurity C<br>Applications Deshydroxy Bicalutamide (Bicalutamide EP Impurity C) is an impuirty of Bicalutamide. Bicalutamide intermediate.<br>References Lysiak, V., et al.: Bioorg. Med. Chem., 13, 671 (2005),<br></p>Formula:C18H14F4N2O3SColor and Shape:Off-WhiteMolecular weight:414.37Ondansetron-d3 Hydrochloride Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A labelled specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000),<br></p>Formula:C18H16D3N3O•HClColor and Shape:NeatMolecular weight:296.393646Terfuboxon
CAS:Controlled Product<p>Applications Terfuboxon is a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br>References Rahman, Md. M. et al.: Food CHem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008);<br></p>Formula:C9H21O3PS2Color and Shape:NeatMolecular weight:272.36Lercanidipine-d3
CAS:Controlled Product<p>Applications Lercanidipine-d3 is a labeled dihydropyridine calcium channel blocker.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bianchi, G., et al.: Pharmacol. Res., 21, 193 (1989); Rimoldi, E., et al.: Acta Therap., 200, 23 (1994)<br></p>Formula:C36H38D3N3O6Color and Shape:NeatMolecular weight:614.752-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
CAS:Controlled Product<p>Applications 2-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole is a drug impurity of Lansoprazole, which is a proton pump inhibitor and used to treat stomach and intestinal ulcers.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000); Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001); Barradell, L.B., et al.: Drugs, 44, 225 (1992); Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002); Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006)<br></p>Formula:C14H12N4O3SColor and Shape:NeatMolecular weight:316.34Paliperidone E-oxime
CAS:Controlled Product<p>Applications Paliperidone E-oxime is an impurity of Paliperidone (P141000), a known orally active antipsychotic agent.<br>References Rao, J., et al.: Pharmacia Lettre, 3, 240 (2011);<br></p>Formula:C23H28F2N4O3Color and Shape:NeatMolecular weight:446.49Des-4-fluorobenzyl Mosapride
CAS:Controlled Product<p>Applications The major metabolite of Mosapride (M731000).<br>References Somogyi, A., et al.: Clin. Pharmacokinet., 8, 463 (1983), Cashman, J., et al.: Drug Metab. Dispos., 21, 587 (1993), Berkman, C., et al.: Biochem. Pharmacol., 50, 565(1995), Blake, B., et al.: Xenobiotica, 25, 377 (1995),<br></p>Formula:C14H20ClN3O3Color and Shape:NeatMolecular weight:313.78Ranitidine N-Oxide
CAS:Controlled Product<p>Impurity Ranitidine EP Impurity E<br>Stability Very Hygroscopic<br>Applications Ranitidine N-Oxide (Ranitidine EP Impurity E) is a metabolite of Ranitidine (R120000).<br></p>Formula:C13H22N4O4SColor and Shape:BeigeMolecular weight:330.40Des [3-(1-Dimethylamino)ethyl] 3-Acetyl Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity C; USP Related Compound D<br>Applications Des [3-(1-dimethylamino)ethyl] 3-acetyl Rivastigmine (Rivastigmine EP Impurity C) is a derivative of Rivastigmine (Tartrate: R541000), and acetylcholinesterase inhibitor that is commonly used to treat dementia associated with Parkinson’s disease and Alzheimer’s disease.<br>References Emre, M., et al.: New. Engl. J. Med., 351, 2509 (2004); Polinsky, R.: Clin. Ther., 20, 634 (1998); Wilkinson, D., et al.: Int. J. Clin. Pract., 56, 441 (2001)<br></p>Formula:C12H15NO3Color and Shape:Off-WhiteMolecular weight:221.25Ramelteon
CAS:Controlled Product<p>Applications Melatonin MT1/MT2 receptor agonist. Sedative, hypnotic.<br>References Yukuhiro, N., et al.: Brain Res., 59, 1027 (2004), Cajochen, C., et al.: Curr. Opin. Invest. Drugs, 6, 114 (2005), Kato, K., et al.: Neuropharmacology, 48, 301 (2005),<br></p>Formula:C16H21NO2Color and Shape:NeatMolecular weight:259.34Chlorpromazine N-Oxide Maleic Acid Salt
CAS:Controlled Product<p>Applications Chlorpromazine N-Oxide Maleic Acid Salt is an impurity of Chlorpromazine (C424750) which has antiemetic; antipsychotic properties.<br>References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990)<br></p>Formula:C21H23ClN2O5SColor and Shape:NeatMolecular weight:450.94Bumadizon
CAS:<p>Applications Bumadizon, is a non-steroidal anti-inflammatory (NSAID) drug.<br>References Okada, Y., et al.: Yakugaku Zasshi, 106, 240 (1986;<br></p>Formula:C19H22N2O3Color and Shape:NeatMolecular weight:326.398-Chlorotheophylline
CAS:<p>Applications A stimulant drug. It can be used as a binding agent to form stable salts of pharmaceutical drugs.<br>References Lyles, M. et al.: J. Med. Chem. 44, 4650 (2001).<br></p>Formula:C7H7ClN4O2Color and Shape:WhiteMolecular weight:214.612,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone
CAS:Controlled Product<p>Impurity Voriconazole EP Impurity A; Voriconazole USP Related Compound C<br>Applications 2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone (Voriconazole EP Impurity A; Voriconazole USP Related Compound C) is an antifungal activity, particularly toward Candida albicans and Candida parapsilosis<br>References Upadhayaya, R., et al.: Eur. J. Med. Chem., 39, 579 (2004), Sheng, C., et al.: J. Med. Chem., 49, 2512 (2006),<br></p>Formula:C10H7F2N3OColor and Shape:BeigeMolecular weight:223.183-Chloro-4-nitropyridine N-oxide
CAS:Formula:C5H3ClN2O3Purity:95%Color and Shape:SolidMolecular weight:174.54(R)-4-Hydroxy Propranolol Hydrobromide
CAS:Controlled Product<p>Applications The main metabolite of (R)-Propranolol.<br>References Shwed, J., et al.: Xenobiotica, 22, 973 (1992), Fujita, K., et al.: Biol. Pharm. Bull., 22, 446 (1999), Walle, U., et al.: Drug Metab. Dispos., 30, 564 (2002),<br></p>Formula:C16H21NO3·HBrColor and Shape:NeatMolecular weight:356.25Desfluoro Ezetimibe
CAS:Controlled Product<p>Impurity Ezetimibe Desfluoroaniline Analog (USP)<br>Stability Hygroscopic<br>Applications An impurity of the cholesterol absorption inhibitor Ezetimibe (E975000). Ezetimibe Desfluoroaniline Analog (USP).<br>References Anon.: IP.com J., 7, 4 (2007);<br></p>Formula:C24H22FNO3Color and Shape:White To Off-WhiteMolecular weight:391.435-Chloro-N-cyclohexylpentanamide
CAS:<p>Stability Hygroscopic<br>Applications 5-Chloro-N-cyclohexylpentanamide (cas# 15865-18-6) is a compound useful in organic synthesis.<br></p>Formula:C11H20ClNOColor and Shape:NeatMolecular weight:217.7364'-Methylbiphenyl-2-carbonitrile
CAS:Controlled Product<p>Applications 4'-Methylbiphenyl-2-carbonitrile is an intermediate in the synthesis of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase 3α.<br>References Lo Monte, F., et al.: J. Med. Chem., 55, 4407 (2012); Schaarschmidt, D., et al.: ACS. Catalysis., 1, 411 (2011);<br></p>Formula:C14H11NColor and Shape:NeatMolecular weight:193.24Metaflumizone
CAS:<p>Applications Metaflumizone is a semicarbazone insecticide that works by blocking sodium channel in target insects resulting in paralyzation associated with blocking nerve activity. Metaflumizone is useful as a heartworm control treatment.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, Zhe,, et al.: J. Integrat. Agri. 11, 1145 (2012); Kuhn, D., et al.: Modern. Crop. Protect. Compound., 3, 1273 (2012);<br></p>Formula:C24H16F6N4O2Color and Shape:WhiteMolecular weight:506.40Palbociclib N-Aldehyde
CAS:Controlled Product<p>Applications Palbociclib N-Aldehyde is an intermediate in synthesizing Palbociclib N-β-D-Glucuronide Sodium Salt (P139910), a derivative of Palbociclib (P139900) which is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.<br>References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)<br></p>Formula:C25H29N7O3Color and Shape:NeatMolecular weight:475.543-Phenyl-1-propanol
CAS:Controlled Product<p>Impurity Alverine EP Impurity B<br>Applications 3-Phenyl-1-propanol is used as a reagent in the synthesis of Dihydrocinnamyl Cilnidipine (D448605) and is a potent aroma biotransformation product.<br>References Bosse, A.K., et al.: Food Chem., 141, 2952 (2013)<br></p>Formula:C9H12OColor and Shape:ColourlessMolecular weight:136.19Naloxegol Oxalate
CAS:<p>Applications Naloxegol Oxalate is an oxalate form of Naloxegol (N284470) which is a peripherally-selective opioid antagonist.<br>References Seifert, R., et al.: G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity, 227 (2012)<br></p>Formula:C34H53NO11•C2H2O4Color and Shape:NeatMolecular weight:651.7990034-Desmethyl-4-ethylimidazolyl Nilotinib
CAS:Controlled ProductFormula:C29H24F3N7OColor and Shape:Light Beige To Light BrownMolecular weight:543.54Propiconazole
CAS:Controlled Product<p>Applications Propiconazole is a systemic foliar fungicide. Agricultural fungicide. Useful in cannabis testing kits as a component of pesticide mixes (P698235).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Child, R., et al.: Plant Growth Regul., 13, 203 (1993), Jaleel, C., et al.: Plant Sci., 171, 271 (2006), Jaleel, C., et al.: Pestic Biochem. Physiol., 91, 170 (2008),<br></p>Formula:C15H17Cl2N3O2Color and Shape:YellowMolecular weight:342.22Levofloxacin N-oxide
CAS:Controlled Product<p>Impurity Oxifloxacin EP Impurity F<br>Applications Levofloxacin N-oxide is an impurity of Ofloxacin (O245750), which is a fluorinated quinolone antibacterial.<br>References Horstkotter, C., et al.: J. Chromatography Biomed. Sci. Appli., 754, 169 (2001); Monk, J.P., et al.: Drugs, 33, 346 (1987), Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990)<br></p>Formula:C18H20FN3O5Color and Shape:NeatMolecular weight:377.372-Chloropyridine
CAS:Controlled Product<p>Applications 2-Chloropyridine (2-CPY) has been identified as a trace organic chemical in process streams, wastewater and even drinking water. Furthermore, it appears to be formed as a secondary pollutant during the decomposition of specific insecticides. 2-CPY was found to be genotoxic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Demsia, G., et al.: Mutat. Res., 634, 32 (2007), Stapleton, D., et al.: Water Res., 43, 3964 (2009),<br></p>Formula:C5H4ClNColor and Shape:NeatMolecular weight:113.54Hydroxy-2-phenylpropyl Carbamate
CAS:Controlled Product<p>Applications Hydroxy-2-phenylpropyl Carbamate is an impurity in the synthesis of Felbamate (F231000), an antiepileptic, structurally similar to meprobamate.<br>References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),<br></p>Formula:C10H13NO3Color and Shape:NeatMolecular weight:195.22aR,4S-Brivaracetam
CAS:Controlled ProductFormula:C11H20N2O2Color and Shape:NeatMolecular weight:212.29Nifedipine-d6
CAS:Controlled Product<p>Applications Used as an antihypertensive and antianginal. A labelled dihydorpyridine calcium channel blocker.<br>References Ali, S.L., et al.: Anal. Profiles Drug Subs., 18, 221 (1989), Soons, P.A., et al.: J. Pharm. Biomed. Anal., 9, 475 (1991), Brown, M.J., et al.: Lancet, 356, 366 (2000),<br></p>Formula:C172H6H12N2O6Color and Shape:YellowMolecular weight:352.37N-Desmethyl Clozapine-d8
CAS:Controlled Product<p>Applications A major labelled metabolite of clozapine. A potent and selective 5-HT2C serotonin receptor antogonist.<br>References Kuoppamaki, M. et al.: Eur. J. Pharm. Mol. Pharm. Sect., 245, 179 (1993), Olessen, O.V., et al.: J. Chromatog., 622, 39 (1993), Pirmohamed, M., et al.: J. Pharmacol. Exp. Ther., 272, 984 (1995)<br></p>Formula:C172H8H9ClN4Color and Shape:Light YellowMolecular weight:320.85Phenylbutazone-d9
CAS:Controlled ProductFormula:C192H9H11N2O2Color and Shape:White To Light BrownMolecular weight:317.43N,N’-Bis[Des(5-chloro-2-carvoxythienyl) Rivaroxaban] Urea
CAS:Controlled ProductFormula:C29H32N6O9Color and Shape:WhiteMolecular weight:608.601,1,2-Trimethyl-3-(4-sulfobutyl)benz[e]indolium Inner Salt
CAS:<p>Applications 1,1,2-Trimethyl-3-(4-sulfobutyl)benz[e]indolium Inner Salt is a reactant used in the preparation of liposomally formulated indocyanine green (LP-ICG) derivatives for near infrared fluorescence imaging of lymph nodes.<br>References Toyota, T., et. al.: Bioorg. Med. Chem., 22, 721 (2014)<br></p>Formula:C19H23NO3SColor and Shape:NeatMolecular weight:345.46Teflubenzuron
CAS:Controlled Product<p>Applications Teflubenzuron is an benzoylphenylurea chitin synthesis inhibitor used to control a wide range of insect pests and mites in fruit, vegetable, cereal and seed crops. Teflubenzuron is used in cannabis testing kits as a component of pesticide mixes (P698240).<br>References Carro, A.M., et al.: J. Separat. Sci., 35, 2866 (2012); Brock, T.C.M., et al.: Environ. Sci. Pollu. Res., 19, 3610 (2012);<br></p>Formula:C14H6Cl2F4N2O2Color and Shape:Off-WhiteMolecular weight:381.111-Chloroadamantane
CAS:<p>Impurity Adamantane EP Impurity A<br>Stability Light Sensitive<br>Applications 1-Chloroadamantane, an adamantane derivative shown to exhibit virucidal activity against the Newcastle disease virus in chick embryo fibroblasts. (Adamantane EP Impurity A)<br>References Aigami, K., et al.: J. Med. Chem., 18, 713 (1975)<br></p>Formula:C10H15ClColor and Shape:NeatMolecular weight:170.68N-Nitroso Duloxetine
CAS:Formula:C18H18N2O2SColor and Shape:Colourless To Light YellowMolecular weight:326.413Isoxsuprine Hydrochloride
CAS:Controlled Product<p>Applications A vasilodator drug. It is used in veterinary medicine for the treatment of navicular syndrome and laminitis in horses. It has been shown to be a β-adrenoreceptor antagonist with β-adrenoreceptor agonistic properties, with both characteristics contributing to vasodilation and uterine relaxation. Studies suggest that ut may be useful as a as a tocolytic agent in the treatment of preterm labour.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Erkert, R.S. et al.: J. Vet. Pharmacol. Therap., 25, 81 (2002); Giorgino, F.L. et al.: Arzneim. Forsch., 60, 415 (2010);<br></p>Formula:C18H23NO3·ClHColor and Shape:White To Off-WhiteMolecular weight:337.84Salbutamon Hydrochloride
CAS:<p>Impurity Salbutamol EP Impurity J<br>Applications Salbutamon Hydrochloride (Salbutamol EP Impurity) is a related impurity of Albuterol (A514500) (Salbutamol) (EP).<br>References Price, A., et al.: Drugs, 38, 77 (1989), Beaulieu, N., et al.: J. Pharm. Biom. Anal., 8, 583 (1990), Sagar, K., et al.: J. Pharm. Biomed. Anal., 11, 533 (1993),<br></p>Formula:C13H19NO3·ClHColor and Shape:NeatMolecular weight:273.76Elexacaftor-D3
CAS:Controlled ProductFormula:C26D3H31F3N7O4SColor and Shape:NeatMolecular weight:600.671a,a,a’,a’-Tetramethyl-5-methyl-1,3-benzenediacetonitrile
CAS:Controlled Product<p>Impurity Anastrozole EP Impurity H<br>Applications α,α,α’,α’-Tetramethyl-5-methyl-1,3-benzenediacetonitrile (Anastrozole EP Impurity H) is an intermediate in the synthesis of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Jackson, T., et al.: Org. Biomolec. Chem., 5, 3368 (2007),<br></p>Formula:C15H18N2Color and Shape:White To YellowMolecular weight:226.321-Methyl-12-thioxopyrido[1,2,3,4]imidazole-[1,2-a]benzimidazole-2(12H)-one
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications Lansoprazole (L175000) impurity .<br></p>Formula:C14H9N3OSColor and Shape:Orange To RedMolecular weight:267.31β-D-Glucose Pentaacetate
CAS:Controlled Product<p>Applications D-Glucose pentaacetate was reported to stimulate insulin release in rat pancreatic islets. Only α-D-glucose pentaacetate caused an immediate increase in insulin output. The β-anomer of D-glucose pentaacetate first transiently inhibited insulin release, this initial effect being followed by a secondary rise in secretory rate.<br>References Carpinelli, A., et al.: Mol. Cell Endocrinol., 17, 103 (1980), Hellman, B., et al.: Diab. Metab., 20, 123 (1994), Malaisse, W., et al.: Int. J. Mol. Med., 2, 331 (1998), Sener, A., et al.: Mol. Gen. Metab., 64, 135 (1998),<br></p>Formula:C16H22O11Color and Shape:WhiteMolecular weight:390.34Pimobendan-d3
CAS:Controlled Product<p>Applications Pimobendan-d3, is the labeled analogue of Pimobendan (P447500), a cardiotonic agent.<br>References Yokota, S. et al.: Yakuri Chiryo, 20, 1143 (1992); Yamamoto, M. et al.: Kank. Igaku Ken. Nenpo, 47, 155 (1996); Matsumoto, A. et al.: Cardiovas. Drugs Ther., 12, 595 (1998);<br></p>Formula:C19H15D3N4O2Color and Shape:White To Light YellowMolecular weight:337.39Rac Albuterol-d9
CAS:Controlled Product<p>Applications A labelled β2-adrenoceptor agonist. Bronchodilator; tocolytic.<br>References Miyagawa, N., et al.: Biol. Pharm. Bull., 31, 2260 (2008), Gonzalez-Munoz, C., et al.: Eur. J. Pharmacol., 607, 151 (2009), Kern, C., et al.: J. Med. Chem., 52, 1773 (2009),<br></p>Formula:C132H9H12NO3Color and Shape:White To YellowMolecular weight:248.37Mildronate-d3
CAS:Controlled Product<p>Stability Very Hygroscopic<br>Applications Mildronate-d3 is the labeled analogue of Mildronate (M344450), a novel pharmaceutical composition based on a reverse transcriptase inhibitor and meldonium. May contain a significant amount of water.<br></p>Formula:C6H11D3N2O2Color and Shape:White To Off-WhiteMolecular weight:149.211-Descarbamoyl-2-carbamoyl Methocarbamol
CAS:Controlled Product<p>Applications An impurity of the muscle relaxant Methocarbamol (M225950) with lysosomal acid lipase inhibitory effects.<br>References Topliss, J., et al.: J. Med. Chem., 22, 1238 (1979); Rosenbaum, A.I. et al.: J. Med. Chem., 52, 5281 (2010);<br></p>Formula:C11H15NO5Color and Shape:NeatMolecular weight:241.240Benzydamine N-Oxide
CAS:<p>Applications A metabolite of Benzydamine (B209950).<br>References Beaty, N., et al.: J. Biol. Chem., 255, 3817 (1980), Tugnait, M., et al.: Drug Metab. Dispos., 25, 524 (1997), Ubeaud, G., et al.: Eur. J. Pharm. Sci., 8, 255 (1999),<br></p>Formula:C19H23N3O2Color and Shape:NeatMolecular weight:325.45-Benzyl Benzydamine Hydrochloride
CAS:<p>Applications 5-Benzyl Benzydamine is an impurity of Benzydamine hydrochloride (B209950). Benzydamine impurity B.<br></p>Formula:C26H29N3O·ClHColor and Shape:NeatMolecular weight:435.99Loratadine
CAS:Controlled Product<p>Applications A nonsedating-type histamine H1-receptor.<br>References Bruttmann, G., et al.: J. Allergy Clin. Immunol., 83, 411 (1989), Haria, M., et al.: Drugs, 48, 617 (1994)<br></p>Formula:C22H23ClN2O2Color and Shape:WhiteMolecular weight:382.88N-Nitroso Frovatriptan 1
Formula:C14H16N4O2Color and Shape:Off-White To Light YellowMolecular weight:272.3S-(-)-Sulpiride-d3
CAS:Controlled Product<p>Applications Labelled S-(-)-Sulpiride (S689140). Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.<br>References Pitre, D., et al.: Anal. Profiles Drug Subs., 17, 607 (1988), Wagstaff, A.J., et al.: CNS Drugs, 2, 313 (1994),<br></p>Formula:C152H3H20N3O4SColor and Shape:White To Light GreenMolecular weight:344.44(R)-(+)-Bupivacaine Hydrochloride
CAS:<p>Applications (R)-(+)-Bupivacaine Hydrochloride is a local anaesthetic used for epidural and intrathecal anaesthesia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tullar, B., et al.: J. Med. Chem., 14, 891 (1971), Schmidt, A., et al.: Pharm. Res., 22, 2121 (2005),<br></p>Formula:C18H28N2O·HClColor and Shape:NeatMolecular weight:324.894'-Formylbiphenyl-2-carbonitrile
CAS:Controlled Product<p>Applications 4'-Formylbiphenyl-2-carbonitrile is an impurity of Telmisartan (T017000), an angiotensin II receptor antagonist.<br>References Goossen, L.J., et al.: J. Org. Chem., 72, 7473 (2007);<br></p>Formula:C14H9NOColor and Shape:NeatMolecular weight:207.2274tau-Fluvalinate (Mixture of Diastereomers)
CAS:<p>Applications τ-Fluvalinate is a synthetic pyrethroid aracacide. τ-Fluvalinate is commonly used to control Varroa jacobsoni (a parasitic mite) in honey bee colonies.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Delaplane, K.S. et al.: J. Econ. Entomol., 88, 1206 (1995); Ferrer-Dufol, M. et al.: J. Apicul. Res., 34, 147 (1995); Lindberg, C.M. et al.: J. Econ. Entomol., 93, 189 (2000);<br></p>Formula:C26H22ClF3N2O3Color and Shape:Light YellowMolecular weight:502.913-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone (Domperidone Impurity D)
CAS:<p>Impurity Domperidone EP Impurity D<br>Applications An impurity of the gastrokinetic and antinauseant drug Domperidone (D531100).<br></p>Formula:C32H34ClN7O3Purity:>90%Color and Shape:White To Off-WhiteMolecular weight:600.11Lercanidipine 5-Desmethyl-5-Propyl Ester
CAS:<p>Applications Lercanidipine 5-Desmethyl-5-Propyl Ester is an impurity of the dihydropyridine calcium channel blocker Lercanidipine (L179000).<br></p>Formula:C38H45N3O6Color and Shape:NeatMolecular weight:639.7804Nifedipine
CAS:Controlled Product<p>Applications Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker.<br>References Ali, S.L., et al.: Anal. Profiles Drug Subs., 18, 221 (1989), Soons, P.A., et al.: J. Pharm. Biomed. Anal., 9, 475 (1991), Brown, M.J., et al.: Lancet, 356, 366 (2000),<br></p>Formula:C17H18N2O6Color and Shape:Light YellowMolecular weight:346.33Minoxidil β-D-Glucuronide
CAS:Controlled Product<p>Applications Minoxidil β-D-Glucuronide is a metabolite of Minoxidil (M345000), an antihypertensive and antialopecia agent. Minoxidil activates ATP-activated K+ channels.<br>References Thomas, R.C., et al.: J. Pharmaceut. Sci., 64, 1366 (1975),<br></p>Formula:C15H23N5O7Color and Shape:White To BrownMolecular weight:385.37Raltegravir
CAS:Controlled Product<p>Applications Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN.<br>References Hare, S., et al.: Proc. Natl. Acad. Sci. U. S. A., 107, 20057 (2010); Hicks, C., et al.: Clin. Infect. Dis., 48, 931 (2009); Moss, D., et al.: Antimicrob. Agents Chemother., 56, 3020 (2012); Hare, S., et al.: Mol. Pharmacol., 80, 565 (2011)<br></p>Formula:C20H21FN6O5Color and Shape:NeatMolecular weight:444.42Lansoprazole N-Oxide
CAS:Controlled Product<p>Impurity Lansoprazole EP Impurity A<br>Applications Lansoprazole N-Oxide (Lansoprazole EP Impurity A) is an impurity of Lansoprazole (L175000) formed during the bulk synthesis of the drug.<br>References Kubo, K., et al.: Chem. Pharm. Bull., 38, 2853 (1990), Barradell, L., et al.: Drugs, 44, 225 (1992), Aydogmus, Z., et al.: Acta Pharm. Sci., 48, 45 (2006),<br></p>Formula:C16H14F3N3O3SColor and Shape:NeatMolecular weight:385.361-(4-Chloromethyl-2-thiazoyl)guanidine Hydrochloride Salt
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications Reagent used to produce many guanidine based pharmaceuticals<br></p>Formula:C5H7ClN4S·ClHColor and Shape:White To Light BrownMolecular weight:227.11
![11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC988365.webp&w=3840&q=75)
![5-[(2-methyl-4-quinolyl)thio]-1,3,4-thiadiazol-2-amine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF518872.webp&w=3840&q=75)
![N-Nitroso-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-L-valine Methyl Ester-d8](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FN212432.webp&w=3840&q=75)
![[3-[[[2-(Diaminomethyleneamino)-4-thiazolyl]methyl]thio]propionyl]sulfamide Hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD416369.webp&w=3840&q=75)
![2,7-Bis(pyridin-4-ylmethyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF695964.webp&w=3840&q=75)
![2-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM324400.webp&w=3840&q=75)
![Des [3-(1-Dimethylamino)ethyl] 3-Acetyl Rivastigmine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD289320.webp&w=3840&q=75)
![N,N’-Bis[Des(5-chloro-2-carvoxythienyl) Rivaroxaban] Urea](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FB415100.webp&w=3840&q=75)
![1,1,2-Trimethyl-3-(4-sulfobutyl)benz[e]indolium Inner Salt](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FT796740.webp&w=3840&q=75)
![1-Methyl-12-thioxopyrido[1,2,3,4]imidazole-[1,2-a]benzimidazole-2(12H)-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM330550.webp&w=3840&q=75)
![3-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone (Domperidone Impurity D)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD449455.webp&w=3840&q=75)
