Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65630 products of "Quinazoline and Quinoline Derivatives"
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Tert-Butyl (R)-(1-(3-(4-Ethoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)carbamate
CAS:Purity:95%Molecular weight:409.4859924316406N-Nitroso Betahistine
CAS:<p>Applications N-Nitroso Betahistine is an impurity of Betahistine, which is most commonly used to treat the symptoms of Ménière's disease and vertigo. Vasodilator.<br>References Gilligan, P., et al.: J. Med. Chem., 43, 1641 (2000), Keller, P., et al.: Bioorg. Med. Chem., 8, 1213 (2000), Hauger, R., et al.: Pharmacol. Rev., 55, 21 (2003), Han, X., et al.: Bioorg. Med. Chem. Lett., 15, 3870 (2005)<br></p>Formula:C8H11N3OColor and Shape:Colourless To Light YellowMolecular weight:165.1922-(4-n-Butoxybenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Purity:97.0%Molecular weight:332.41000366210943-(6-Bromopyridin-2-yl)-6-chloroimidazo[1,2-a]pyridine
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:308.55999755859375N-Desmethyl 8-Chloro-5H-dibenzo[b,e][1,4]diazepine Clozapine
CAS:Controlled Product<p>Impurity CLOZAPINE EP IMPURITY B<br>Applications N-Desmethyl 8-Chloro-5H-dibenzo[b,e][1,4]diazepine Clozapine is a Clozapine (C587500) impurity, an antipsychotic.<br>References Stille, et al: Farnaco, Ed. Prat., 26, 603 (1971), Hane, J.M., et al.: Psychopharmacol. Bull., 24, 62 (1988), Meltzer, H.Y.: J. Clin. Psychiatry, 55, Suppl. B, 47 (1994)<br></p>Formula:C30H24Cl2N6Color and Shape:NeatMolecular weight:539.46Apixaban-d3
CAS:Controlled Product<p>Applications Apixaban-d3 is labelled Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Formula:C25H22D3N5O4Color and Shape:White To Off-WhiteMolecular weight:462.52Flubendazole alcohol
CAS:Controlled Product<p>Applications Flubendazole alcohol is a metabolite of the anthelmintic Flubendazole (F418500).<br>References Meuldermans, W., et al.: Eur. J. Drug Metab. Pharmacokinet., 1, 35 (1976), Dusi, G., et al.: J. Pharmaceut. Biomed. Anal., 38, 375 (2005), Cvilink, V., et al.: Vet. Parasitol., 151, 242 (2008),<br></p>Formula:C16H14FN3O3Color and Shape:White To Off-WhiteMolecular weight:315.30rac Epinephrine-d3
CAS:Controlled ProductFormula:C92H3H10NO3Color and Shape:NeatMolecular weight:186.22N,N'-Dicyclohexylurea
CAS:Controlled Product<p>Impurity Lomustine USP Related Compound C<br>Applications N,N'-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C.<br>References Garriga, M., et al.: Chemosphere, 82, 1604 (2011)<br></p>Formula:C13H24N2OColor and Shape:Light YellowMolecular weight:224.34Irbesartan
CAS:Controlled Product<p>Applications An angiotensin II type 1 (AII1)-receptor antagonist.<br>References Gillis, J.C. and Markham, A.: Drugs, 54, 885 (1997), Chando, T.J., et al.: Drug. Metabol. Dispos., 26, 408 (1998), Massie, B., et al.: New Eng. J. Med., 359, 2456 (2008), Ren, X., et al.: Pharmacol., 83, 80 (2009),<br></p>Formula:C25H28N6OColor and Shape:NeatMolecular weight:428.53N,O-Dibenzoyl-L-tyrosine (>90%)
CAS:Controlled Product<p>Applications N,O-Dibenzoyl-L-tyrosine is an impurity of Tiropramide (T446900). Tiropramide impurity A.<br>References Fox, S.W., et al.: Arch. Biochem., 25, 13 (1950),<br></p>Formula:C23H19NO5Purity:>90%Color and Shape:White To Off-WhiteMolecular weight:389.4N-nitroso Rasagiline
CAS:Controlled ProductFormula:C12H12N2OColor and Shape:NeatMolecular weight:200.237Bupivacaine Hydrochloride
CAS:Controlled Product<p>Applications Bupivacaine HCl (cas# 18010-40-7) is a useful research chemical.<br></p>Formula:C18H28N2O·ClHColor and Shape:NeatMolecular weight:324.894-(3-Aminophenyl)-3-morpholinone
CAS:Controlled Product<p>Applications 4-(3-Aminophenyl)-3-morpholinone is an intermediate during the preparation of imidazothiazoles as protein kinase inhibitors for treating cancers.<br>References Bamaung, N., et al.: PCT Int. Appl. (2009), WO 2009070516 A1 20090604.<br></p>Formula:C10H12N2O2Color and Shape:NeatMolecular weight:192.2142-Ethylbenzofuran
CAS:Controlled Product<p>Applications 2-Ethylbenzofuran is used in the synthesis of benzofurans as potential antianginal agents. They are also used in the preparation of 2-arylpyridines that are used in the synthesis of complexes with physical properties.<br>References Goldenberg, C. et al.: Eur. j. Med. Chem., 12, 81 (1977); Baloch, M. et al.: Eur. J. Med. Chem., 2012, 4454 (2012);<br></p>Formula:C10H10OColor and Shape:NeatMolecular weight:146.191-(5-(BENZYLOXY)PYRIDIN-2-YL)CYCLOPROPANECARBOXYLIC ACID
Purity:95.0%Molecular weight:269.299987792968751-(3-Chlorophenyl)-3-thiophen-2-yl-1H-pyrazole-5-carboxylic acid
CAS:Purity:= 98% (HPLC)Molecular weight:304.75AR-C133913XX
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications AR-C133913XX is an metabolte of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004); Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)<br></p>Formula:C14H22N6O4SColor and Shape:NeatMolecular weight:370.43Adrafinil
CAS:Controlled ProductFormula:C15H15NO3SColor and Shape:Off-White Light Orange ColourMolecular weight:289.351,5-Dihydroxyempagliflozin
CAS:Controlled ProductFormula:C23H29ClO8Color and Shape:NeatMolecular weight:468.924,7-Bis(5-bromothiophen-2-yl)benzo[c][1,2,5]thiadiazole
CAS:Purity:98%Color and Shape:SolidMolecular weight:458.20001220703125Nortilidine-d3 Hydrochloride
CAS:Controlled ProductFormula:C162H3H18NO2·ClHColor and Shape:NeatMolecular weight:298.828-methyl-4-(pyridine-3-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Purity:95.0%Molecular weight:305.3340148925781Norketamine-d4
CAS:Controlled Product<p>Applications A labelled metabolite of Ketamine (K165300).<br>References Sullivan, H., et al.: J. Med. Chem., 16, 909 (1973), Moreton, J., et al.: J. Pharmacol. Exp. Ther., 203, 303 (1977), Lin, H., et al.: J. Food Drug Anal., 13, 107 (2005),<br></p>Formula:C12H10D4ClNOColor and Shape:NeatMolecular weight:227.722-(((3,5-Dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole
CAS:Purity:95.0%Molecular weight:315.3900146484375Ref: 10-F234475
1mgTo inquire5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquire(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide
CAS:Controlled Product<p>Applications (S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide is used in the synthesis of Vildagliptin (V305000), an oral anti-diabetic drug, and its impurities (H971380) (Impurity A).<br>References Kumar, N., et al.: J. Pharmaceut. Biomed.,119, 114 (2016); Deng, Y., et al.: Lett. Org. Chem., 11, 780 (2014);<br></p>Formula:C7H11ClN2O2Color and Shape:NeatMolecular weight:190.63Acetamiprid
CAS:Controlled Product<p>Applications A novel neonicotinid insecticide against Holotrichia consanguinea in sugarcane. Reports show that when exposed to neonicotinid pesticides honeybees have problems returnibg home after foraging and bumblebee colonies grow poorly and produce fewer queens. Used in Pesticide detection. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Srivastava, A., et al.: Indian Sugar, 32, 673 (1983), Fleming, R., et al.: J. Econ. Entomol., 78, 1179 (1985), Rao, Ch.V., et al.: Pestology, 35, 47 (2011), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:C10H11ClN4Color and Shape:Colourless To WhiteMolecular weight:222.67Prochlorperazine Sulfoxide-d3
CAS:Controlled Product<p>Applications A labelled metabolite of Prochlorperazine.<br>References Finn, A., et al.: J. Clin. Pharmacol., 45, 1383 (2005),<br></p>Formula:C202H3H21ClN3OSColor and Shape:Off WhiteMolecular weight:392.96N”Nitrosoketamine
CAS:Controlled ProductFormula:C13H15ClN2O2Color and Shape:White To Light YellowMolecular weight:266.7234-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride
CAS:<p>Applications 4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride is a derivative of (4-Methoxyphenyl)hydrazine Hydrochloride (M265880). It is a useful synthetic intermediate for the preparation of Indomethacin (I641000); a potent, time-dependent, nonselective inhibitor of the cyclooxygenase enzymes COX-1 and COX-2.<br>References Blobaum, Anna L., et al.: ACS Med. Chem. Lett., 4(5), 486-490 (2013); Prusakiewicz, Jeffery J., et al.: Biochemistry, 43(49), 15439-15445 (2004)<br></p>Formula:C14H13ClN2O2·HClColor and Shape:NeatMolecular weight:313.181,3-Bis(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiourea
CAS:Purity:98%Molecular weight:448.54998779296875N-Nitrosooxprenolol
CAS:Controlled ProductFormula:C15H22N2O4Color and Shape:Light YellowMolecular weight:294.3463-(4-Fluorophenyl)-1-phenyl-1H-pyrazole-4-carboxaldehyde
CAS:Purity:95.0%Molecular weight:266.27499389648442-Bromoacetic Acid
CAS:<p>Applications Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);<br></p>Formula:C2H3BrO2Color and Shape:Light YellowMolecular weight:138.95Dolutegravir (0.1 mg/mL in Methanol)
CAS:Formula:C20H19F2N3O5Color and Shape:ColourlessMolecular weight:419.38(S)-Efavirenz
CAS:<p>Applications A nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995),<br></p>Formula:C14H9ClF3NO2Color and Shape:NeatMolecular weight:315.68Ketanserin
CAS:<p>Applications An antihypertensive, with affinity for multiple GPCR receptors.<br>References Zhu, Y., et al.: Biol. Pharm. Bull., 32, 1173 (2009), Shen, K., et al.: J. Pharm. Pharmacol., 61, 517 (2009), Brea, J., et al.: Mol. Pharmacol., 75, 1380 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Formula:C22H22FN3O3Color and Shape:NeatMolecular weight:395.43Nisoldipine
CAS:Controlled Product<p>Applications Dihydropyridine calcium channel blocker. Antihypertensive and antianginal.<br>References Kazda, S., et al.: Arzneimittel-Forsch., 30, 2144 (1980), Pasanisi, F., et al.: Eur. J. Clin. Pharmacol., 29, 21 (1985), Lam, J., et al.: J. Am. Col. Cardiol., 6, 447 (1985)<br></p>Formula:C20H24N2O6Color and Shape:YellowMolecular weight:388.41Teneligliptin Sulfoxide (Mixture of Diastereomers)
Controlled Product<p>Applications Teneligliptin Sulfoxide, is an impurity of Teneligliptin (T018300) which is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. Tenegliptin is eliminated from the via excretion, and has a half-life of 24.2 hours in the human body.<br>References Goda, M. & Kadowaki, T.: Drugs Today, 49, 615 (2013); Kishimoto, M.: Diabetes Metab. Syndr. Obes., 6, 187 (2012)<br></p>Formula:C22H30N6O2SColor and Shape:NeatMolecular weight:442.581-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl] Aripiprazole
CAS:<p>Impurity Aripiprazole Impurity 4<br>Applications 1-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl] Aripiprazole is a synthetic impurity of the drug aripiprazole (A771000). Aripiprazole is a novel atypical antipsychotic drug used in the treatment of schizophrenia. Aripiprazole Impurity 4<br>References Filijovic, N. D., et al.: Acta Chromatogr., 26, 13 (2014)<br></p>Formula:C36H42Cl2N4O4Color and Shape:White To Off-WhiteMolecular weight:665.649Captopril-d3
CAS:Controlled Product<p>Applications Orally active angiotensin-converting enzyme (ACE) inhibitor.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978),<br></p>Formula:C9D3H12NO3SColor and Shape:White SolidMolecular weight:220.307-Hydroxy Risperidone
CAS:Controlled ProductFormula:C23H27FN4O3Color and Shape:NeatMolecular weight:426.48Alogliptin Benzoate
CAS:<p>Applications Alogliptin Benzoate is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Alogliptin Benzoate is used in the treatment of type 2 diabetes.<br>References Wang, Y., et. al.: Drugs Future, 33, 7 (2008); Lynn, F., et al.: Diabetes, 50, 1004 (2001); Trumper, A., et al.: J. Endocrinol., 174, 233 (2002); Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009)<br></p>Formula:C18H21N5O2·C7H6O2Color and Shape:NeatMolecular weight:461.516-Bromo-N-methylquinazolin-2-amine
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:238.087997436523442-(1,3-Dimethyl-1 H -pyrazol-4-yl)-quinoline-4-carboxylic acid
CAS:Color and Shape:SolidMolecular weight:267.2879943847656(S)-(-)-Dropropizine N,N-Dioxide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications (S)-(-)-Dropropizine N,N-Dioxide, is an impurity of (S)-(-)-Dropropizine (D681500), S-Form of Dropropizine. Cough suppressive phenylpiperazine derivative. Antitussive.<br>References Bakken, G., et al.: J. Med. Chem., 43, 4534 (2000), Salunkhe, M., et al.: Enz. Microb. Technol., 28, 333 (2001), Atul, B., et al.: J. Pharm. Sci., 91, 2067 (2002),<br></p>Formula:C13H20N2O4Color and Shape:NeatMolecular weight:268.31
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