Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65541 products of "Quinazoline and Quinoline Derivatives"
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2-(CHLOROMETHYL)-4-(2,2,3,3,4,4,4-HEPTAFLUOROBUTOXY)PYRIDINE
CAS:Purity:95.0%Molecular weight:325.60998535156257-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid, 90%
CAS:Controlled Product<p>Impurity Norfloxacin EP Impurity A; Norfloxacin USP Related Compound A (7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-d<br>Applications 7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid (Norfloxacin EP Impurity A) is a Norfloxacin intermediate. Norfloxacin EP Impurity A; Norfloxacin USP Related Compound A (7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid).<br>References Piganeau, N., et al.: J. Mol. Biol., 312, 1177 (2001), Rameshkumar, N., et al.: Eur. J. Med. Chem., 38, 1001 (2003), You, Q., et al.: J. Med. Chem., 52, 5649 (2009),<br></p>Formula:C12H9ClFNO3Purity:90%Color and Shape:NeatMolecular weight:269.66(3S,4S,3’S)-Ezetimibe
CAS:<p>Applications (3S,4S,3’S)-Ezetimbe is a 3-epimer impurity of Ezetimibe (E975000), a cholesterol absorption inhibitor.<br>References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>Formula:C24H21F2NO3Color and Shape:Off-WhiteMolecular weight:409.43Toltrazuril
CAS:Controlled Product<p>Applications A triazinetrione anticoccidial. Coccidiostat.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Eberts, T., et al.: Clin. Chem., 25, 1440 (1979), Goodwin, M., et al.: Avian Dis., 29, 630 (1985), Sorensen, S., et al.: Clin. Chim. Acta, 264, 103 (1997), Conway, D., et al.: Poult. Sci., 280, 426 (2001),<br></p>Formula:C18H14F3N3O4SColor and Shape:Off WhiteMolecular weight:425.382-((6-Chloropyridin-3-yl)methyl)isoindoline-1,3-dione
CAS:Purity:95.0%Molecular weight:272.690002441406254-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
CAS:Controlled Product<p>Applications 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.<br>References Mross, K., et al.: Clin. Cancer Res., 18, 2658 (2012); Stiehl, J., et al. Process for Preparation of Regorafenib. PCT Int. Appl. 2011128261. Oct 20, 2011; Van Cutsem, E., et al.: J. Clin. Oncol., 30, 3502 (2012)<br></p>Formula:C13H12FN3O2Color and Shape:Dark Orange To Red BrownMolecular weight:261.25rac Kynurenine
CAS:Controlled Product<p>Applications A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. An amino acid produced in the body from tryptophan.<br>References Swartz, K., et al.: J. Neurosci., 10, 2965 (1990), Hasegawa, H., et al.: Anal. Bioanal. Chem., 377, 886 (2003), Tsai, Y., et al.: Anal. Biochem., 319, 34 (2003), Mitsuhashi, S., et al.: Anal. Chim. Acta, 584, 315 (2007),<br></p>Formula:C10H12N2O3Color and Shape:NeatMolecular weight:208.21(S)-(-)-4’-Hydroxyphenyl Carvedilol
CAS:Controlled Product<p>Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α1-blocking activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Formula:C24H26N2O5Color and Shape:NeatMolecular weight:422.47Mirabegron O-Glucuronide Sodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Mirabegron O-Glucuronide Sodium Salt is the is related to the compound Mirabegron O-Glucuronide (M364905) whcich is a metabolite of Mirabegron (M364900).<br>References van Teijilingen, R., et al.: J. Chromat. B., 887, 102 (2012)<br></p>Formula:C27H31N4O8S·xNaColor and Shape:NeatMolecular weight:572.632-((6,7-DIMETHOXYQUINAZOLIN-4-YL)THIO)-5-METHYL-1,3,4-THIADIAZOLE
CAS:Purity:95.0%Molecular weight:320.3900146484375Desmethyl Doxylamine
CAS:<p>Impurity Doxylamine EP Impurity C<br>Applications Desmethyl Doxylamine is an impurity of Doxylamine (D562000), an H1 Histamine receptor antagonist used as a antihistaminic and sedative agent.<br>References Pande, S.S., et al.: Int. J. Pharmtech. Res., 3, 209 (2011); Tiford, C.H., et al.: J. Am. Chem. Soc., 70, 4001 (1948);<br></p>Formula:C16H20N2OColor and Shape:NeatMolecular weight:256.343-(4-Bromo-5-methyl-3-trifluoromethyl-pyrazol-1-yl)-propionic acid
CAS:Formula:C8H8BrF3N2O2Purity:95.0%Color and Shape:SolidMolecular weight:301.0634-[2-(2-methoxyethoxy)ethoxy]-6-(pyridin-2-yl)-2,2'-bipyridine
CAS:Purity:95.0%Molecular weight:351.4060058593754-((2R,3S,6S)-6-(4-Fluorophenyl)-3-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenol (Ezetimibe Impurity)
<p>Applications 4-((2R,3S,6S)-6-(4-Fluorophenyl)-3-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenol, is a diol impurity of Ezetimibe (E975000), a drug that lowers plasma cholesterol levels.<br>References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>Formula:C18H19FO3Color and Shape:NeatMolecular weight:302.34Sulindac Sulfone Acyl-β-D-Glucuronide
CAS:Controlled Product<p>Applications Sulindac Sulfone Acyl-β-D-Glucuronide is the major metabolite of the non-steroidal anti-inflammatory drug Sulindac (S699215) in plasma and urine.<br>References Hucker, H.B., et al.: Drug Metab. Dispos., 1, 721 (1973),<br></p>Formula:C26H25FO10SColor and Shape:NeatMolecular weight:548.538-Methyl-2-pyridin-4-yl-quinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:264.283996582031254-{3-[4-(Trifluoromethyl)phenyl]-1H-pyrazol-4-yl}pyridine
CAS:Formula:C15H10F3N3Purity:95.0%Molecular weight:289.261Rebamipide 3-Chloro Impurity (>80%)
CAS:Controlled Product<p>Applications Rebamipide 3-Chloro Impurity (CAS# 90098-05-8) is a useful research chemical compound.<br></p>Formula:C19H15ClN2O4Purity:>80%Color and Shape:White To Off-WhiteMolecular weight:370.78641-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol
CAS:Controlled Product<p>Applications 1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a degradation product of phenylephrine during the synthesis of the anti-cold medicine.<br>References Dousa, M. et al.: J. Pharm. Biomed. Anal., 55, 949 (2011);<br></p>Formula:C15H17NO4Color and Shape:NeatMolecular weight:275.3Apremilast
CAS:<p>Applications Apremilast is an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis.<br>References Gan, E., et al.: BioDrugs, 27, 359 (2013); Pathan, E., et al.: Annal. Rheum. DIs., 72, 1475 (2013);<br></p>Formula:C22H24N2O7SColor and Shape:NeatMolecular weight:460.50cis-Hydroxy Perhexiline(Mixture of Diastereomers)
CAS:Controlled Product<p>Applications A metabolite of Perhexiline.<br>References Shah, R., et al.: Br. Med. J., 284, 295 (1982), Gould, B., et al.: Xenobiotica, 16, 491 (1986), Marquet, P., et al.: Ther. Drug Monit., 24, 255 (2002), Sallustio, B., et al.: Br. J. Clin. Pharmacol., 54, 107 (2002),<br></p>Formula:C19H35NOColor and Shape:NeatMolecular weight:293.49(S)-2-Aminobutyramide Hydrochloride
CAS:Controlled Product<p>Impurity Levetiracetam USP Related Compound B<br>Applications Levetiracetam USP Related Compound B<br></p>Formula:C4H10N2O·ClHColor and Shape:White To Off-WhiteMolecular weight:138.60Nepafenac
CAS:<p>Applications A non-steroidal anti-inflammatory with analgesic activity; selective COX-2 inhibitor. Prodrug of Amfenac.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Walsh, D.A., et al.: J. Med. Chem., 33, 2296 (1990), Gamache, D.A., et al.: Inflammation, 24, 357 (2000), Lindstrom, R., et al.: Curr. Med. Res. Opin., 22, 397 (2006),<br></p>Formula:C15H14N2O2Color and Shape:NeatMolecular weight:254.28Chlorpromazine Sulfoxide
CAS:<p>Impurity Chlorpromazine EP Impurity A<br>Applications Chlorpromazine Sulfoxide is a derivative of Chlorpromazine Hydrochloride (C424750), which is a dopamine antagonist of the typical antipsychotic class of medications possessing additional antiadrenergic, antiserotonergic, anticholinergic and antihistaminergic properties used for schizophrenia treatment.<br>References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990), Yuhas, D., Svi. Smer. Mind, (March 2003),<br></p>Formula:C17H19ClN2OSColor and Shape:Light YellowMolecular weight:334.86(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS:<p>Applications (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton's tyrosine kinase. It is also an intermediate for Ibrutinib (I124970) derivatives.<br>References Chen, W., et al.: PCT Int. Appl. (2011), WO 2011046964 A2 20110421<br></p>Formula:C22H22N6OColor and Shape:White To Light YellowMolecular weight:386.45Deferiprone
CAS:Controlled Product<p>Applications A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transferrin and ferritin in vitro.<br>References Kontoghiorghes, G.J.: Lancet I, 817 (1985), Kontoghiorghes, G.J., et al.: Br. J. Haematol., 62, 607 (1986), Kontoghiorghes, G.J., et al.: Biochem. Biophys. Acta, 869, 141 (1986), Kontoghiorghes, G.J., et al.: Arzneim.-Forsch., 37, 1099 (1987),<br></p>Formula:C7H9NO2Color and Shape:White To Off-WhiteMolecular weight:139.15Tricyclazole
CAS:Controlled Product<p>Applications Tricyclazole is an common active ingredient in several commercial fungicide products used to control rice blast fungus, in transplanted and direct-seeded rice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dhingani, J.C., et al.: J. Pure. App. Microbiol., 6, 1683 (2012); Jeong, S.A., et al.: Bull. Environ. Contamin. Toxicol., 89, 1181 (2012);<br></p>Formula:C9H7N3SColor and Shape:BeigeMolecular weight:189.241-(4,5-Dihydro-1H-imidazol-2-yl)-3,5-dimethyl-1H-pyrazole hydrobromide
CAS:Purity:95.0%Molecular weight:245.12399291992188(2E)-1-{[1,1'-biphenyl]-4-yl}-3-(thiophen-2-yl)prop-2-en-1-one
CAS:Purity:95.0%Molecular weight:290.3800048828125Raloxifene
CAS:<p>Raloxifene (LY139481) is an estrogen receptor modulator exhibiting estrogen agonist and antagonist activity at different sites, with antiviral activity.</p>Formula:C28H27NO4SPurity:99.39%Color and Shape:Light-Yellow SolidMolecular weight:473.584'-(4-Methoxycarbonylphenyl)-2,2':6',2''-terpyridine
CAS:Purity:97%Molecular weight:367.40798950195311-(3-Carboxy-2-pyridyl)-4-methyl-2-phenylpiperazine
CAS:Controlled Product<p>Applications Mirtazapine (M365000) impurity.<br>References Reddy, T. et al.; J. Liq. Chromatogr. R. T. 31, 1204 (2008)<br></p>Formula:C17H19N3O2Color and Shape:NeatMolecular weight:297.354-Fluoro-3-chloroaniline
CAS:Controlled Product<p>Applications 4-Fluoro-3-chloroaniline, is an organic Fluorinated building block used for the synthesis of pharmaceutical and biologically active compounds such as, novel 6-Fluorobenzothiazole-substituted pyrazole analogues, having antiinflammatory activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reddy, D. R. S., et al.: Pharma Chemica., 5, 207 (2013);<br></p>Formula:C6H5ClFNColor and Shape:NeatMolecular weight:145.56
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