Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65580 products of "Quinazoline and Quinoline Derivatives"
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ent-Ezetimibe
CAS:<p>Applications An enantiomeric impurity of Ezetimibe (E975005).<br></p>Formula:C24H21F2NO3Color and Shape:White To Off-WhiteMolecular weight:409.43Medetomidine-13C,d3 Hydrochloride
CAS:Controlled Product<p>Applications Labelled α2-adrenergic agonist. Sedative; analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>Formula:CC122H3H13N2·ClHColor and Shape:White To Light YellowMolecular weight:240.754-OXO-5-(THIOPHEN-2-YLMETHYL)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE-3-CARBOXYLIC ACID
CAS:Purity:95.0%Molecular weight:277.29998779296875L-Lysine Clonixinate
CAS:<p>Applications L-Lysine Clonixinate is a non-morphinic andalgesic.<br>References Krymchantowski, A., et al.: Curr. Ther. Res., 64, 505 (2003), Di Girolamo, G., et al.: Brit. J. Pharmacol., 141, 1234 (2004),<br></p>Formula:C13H11ClN2O2·C6H14N2O2Color and Shape:Off WhiteMolecular weight:408.884-Hydroxybenzhydrazide
CAS:Controlled Product<p>Applications 4-Hydroxybenzhydrazide works as an indicator in the determination of carbohydrates. Tissue (liver) bounded 4-Hydroxybenzhydrazide, the acid-hydrolyzable side chain of Nifuroxazide (N458500) can be used as a marker to monitor it’s residue in chicken.<br>References Lever, M., et al.: Anal. Biochem., 139, 205 (1984); Rocco, M., et al.: Anal. Biochem., 377, 251 (2008); Gao, F., et al.: J. Sci. Food Agr., 93, 2172 (2013)<br></p>Formula:C7H8N2O2Color and Shape:WhiteMolecular weight:152.15Cloperastine Fendizoate
CAS:<p>Stability Hygroscopic<br>Applications Cloperastine fendizoate is used in the treatment of chronic non-productive cough. Antitussive. it is the salt of Cloperastine (CAS:3703-76-2)<br>References Aliprandi, P. et al.: Clin. Drug Invest. 22, 209 (2002)<br></p>Formula:C20H24ClNO·C20H14O4Color and Shape:White To Off-WhiteMolecular weight:648.19Ref: 10-F673022
1gTo inquire2gTo inquire5gTo inquire10gTo inquire100mgTo inquire250mgTo inquire500mgTo inquire2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-n-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazol-4-yl)propanamide
CAS:Purity:97%Molecular weight:390.4800109863281Loxapine-d8 Hydrochloride (Major)
CAS:Controlled ProductFormula:C18H10D8ClN3O·xHClColor and Shape:White To Off-WhiteMolecular weight:372.322-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one
CAS:Purity:98+%Molecular weight:340.385986328125Ref: 10-F869389
1gTo inquire5mgTo inquire10mgTo inquire25mg227.00€50mg353.00€100mgTo inquire250mgTo inquire1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,6-diol
CAS:Controlled Product<p>Applications 1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a degradation product of phenylephrine during the synthesis of the anti-cold medicine.<br>References Dousa, M. et al.: J. Pharm. Biomed. Anal., 55, 949 (2011);<br></p>Formula:C15H17NO4Color and Shape:NeatMolecular weight:275.30N-Carbamoyl Linagliptin
CAS:Controlled Product<p>Applications N-Carbamoyl Linagliptin is a derivative of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Formula:C26H29N9O3Color and Shape:NeatMolecular weight:515.577-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
CAS:Controlled Product<p>Applications Gefitinib intermediate.<br>References Kelly, L., et al.: Cancer Cell., 1, 421 (2002), Pandey, A., et al.: J. Med. Chem., 45, 3772 (2002), Ciardiello, F., et al.: Exp. Opin Emerg. Drugs, 8, 501 (2003), Caponigro, F., et al.: Curr. Opin Oncol., 16, 225 (2004),<br></p>Formula:C16H21N3O4Color and Shape:NeatMolecular weight:319.362-(5-amino-3-tert-butyl-1H-pyrazol-1-yl)-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one
CAS:Purity:95.0%Molecular weight:273.3399963378906Metomidate Hydrochloride
CAS:Controlled Product<p>Applications Metomidate Hydrochloride is used as an anesthetic for veterinary use.<br>References Harvey, B., et al.: Vet. Rec. 122(8), 174-7 (1988); Green, C. J., et al.: Lab. Anim., 15(2), 171-5 (1981); Cadle, D. R., et al.: Vet. Rec., 98(5), 91-2 1976); Massee, K. C., et al.: Aquaculture, 134(3-4), 351-359 (1995)<br></p>Formula:C13H14N2O2·ClHColor and Shape:White To Off-WhiteMolecular weight:266.72Ref: 10-F025806
1gTo inquire2gTo inquire5gTo inquire10gTo inquire100mgTo inquire250mgTo inquire500mgTo inquire1,1'-Bis(pyridin-4-ylmethyl)-1H,1'h-2,2'-biimidazole
CAS:Purity:98%Molecular weight:316.36801147460944-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide
CAS:Formula:C20H14F4N4O2SColor and Shape:NeatMolecular weight:450.41Northiaden
CAS:Controlled Product<p>Applications A metabolite of Dothiepin.<br>References Atkinson, H., et al.: Clin. Pharmacokin., 18, 151 (1990), Hagg, S., et al.: Br. J. Clin. Pharmacol., 49, 286 (2000), Fleishaker, J., et al.: Adv. Drug Deliv. Rev., 55, 643 (2003), Katritzky, A., et al.: Bioorg. Med. Chem., 12, 3027 (2004),<br></p>Formula:C18H19NSColor and Shape:NeatMolecular weight:281.425-Chloro Dasatinib
CAS:Controlled ProductFormula:C22H25Cl2N7O2SColor and Shape:NeatMolecular weight:522.45N-Nitroso Nitrofurantoin impurity R
Controlled ProductFormula:C7H6N4O6Color and Shape:NeatMolecular weight:242.14574rac-Paroxetine-d4 Hydrochloride
CAS:Controlled Product<p>Applications rac-Paroxetine-d4 Hydrochloride is a racemic labeled analogue of Paroxetine Hydrochloride (P205750), a selective serotonin reuptake inhibitor. Used as an antidepressant.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978); Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982)<br></p>Formula:C19H17D4ClFNO3Color and Shape:White To Light BrownMolecular weight:369.85MDV 3100 (Enzalutamide)
CAS:Controlled Product<p>Applications MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.<br>References Scher, H.I. et al.: Lancet, 375, 1437 (2010); Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010); Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2011);<br></p>Formula:C21H16F4N4O2SColor and Shape:WhiteMolecular weight:464.44Flubendazole
CAS:<p>Applications An anthelmintic.<br>References Thienpont, D., et al.: Arzneimittel-Forsch., 28, 605 (1978), Vanparijs, O., et al.: Vet. Parasitol, 5, 237 (1979),<br></p>Formula:C16H12FN3O3Color and Shape:ColourlessMolecular weight:313.28Mosapride Citric Amide Disodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Disodium salt of Mosapride (M731000) derivative.<br>References Yoshida, N., et al.: Arch. Int. Pharmacodyn. Ther., 300, 51 (1989), Yatera, S., et al.: Japan. Pharmacol. Ther., 21, 21 (1993), Ruth, M., et al.: Aliment Pharmacol. Ther., 12, 35 (1998),<br></p>Formula:C27H29ClFN3Na2O9Color and Shape:NeatMolecular weight:639.96(S)-Thalidomide
CAS:<p>(S)-Thalidomide ((S)-(-)-Thalidomide) has anti-angiogenic activity and pro-apoptotic activity and can be used in the study of erythema nodosum in leprosy.</p>Formula:C13H10N2O4Purity:99.89%Color and Shape:NeedlesMolecular weight:258.23Valsartan Methyl Ester
CAS:Controlled Product<p>Impurity Valsartan USP Related Compound E<br>Applications Valsartan Methyl Ester (Valsartan USP Related Compound E) is an analog of Valsartan (V095750), is a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Formula:C25H31N5O3Color and Shape:NeatMolecular weight:449.55N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:277.330993652343752-{[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-5,5-dimethylcyclohexane-1,3-dione
CAS:Molecular weight:404.8900146484375exo-Granisetron
CAS:<p>Impurity Granisetron EP Impurity F<br>Applications Granisetron Impurity F. Granisetron EP Impurity F.<br>References Fozard, J. R., et al.: Br. J. Pharmacol., 61, 130 (1977), Bradley, P.B., et al.: Neuropharmacology, 25, 563 (1986),<br></p>Formula:C18H24N4OColor and Shape:NeatMolecular weight:312.41Cyanuric Acid (1 mg/10 mL in 84:16% ACN:H2O)
CAS:Controlled ProductFormula:C3H3N3O3Color and Shape:Single SolutionMolecular weight:129.07Ramifenazone
CAS:<p>Applications Analgesic, antipyretic, anti-inflammatory.<br>References Tubaro, E., et al.: Arzneim.-Forsch., 20, 1024 (1970),<br></p>Formula:C14H19N3OColor and Shape:NeatMolecular weight:245.32Trityl Chloride
CAS:Controlled Product<p>Applications Trityl Chloride is an alkyl halide commonly used in organic synthesis to introduce the trityl protecting group. Trityl Chloride is used in the preparation of S-trityl-L-cysteine (STLC), a tight-binding inhibitor of Eg5 that prevents mitotic progression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References DeBonis, S. et al.: J. Med. Chem., 51, 1115 (2008); Chadwick, D.J. et al.: J. Chem. Soc. Perk. Trans. Org. Bio-Org. Chem., 1, 102 (1983);<br></p>Formula:C19H15ClColor and Shape:NeatMolecular weight:278.78Altretamine
CAS:Controlled Product<p>Applications An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. Antineoplastic.<br>References Chang, S.C., et al.: Science, 144, 57 (1964), Ames, M.M., et al.: Cancer Res., 39, 5016 (1979), D’Incalci, M., et al.: Br. J. Cancer, 41, 630 (1980),<br></p>Formula:C9H18N6Color and Shape:White Crystalline PowderMolecular weight:210.282-(2-Methoxyphenoxy)ethylamine Hydrochloride
CAS:<p>Impurity Carvedilol EP Impurity E; Carvedilol Impurity E; Carvedilol USP E<br>Applications 2-(2-Methoxyphenoxy)ethylamine Hydrochloride (Carvedilol EP Impurity E; Carvedilol Impurity E; Carvedilol USP E) is an impurity of Carvedilol synthesis.<br>References Smith, L., et al.: J. Med. Chem., 20, 1653 (1977),<br></p>Formula:C9H13NO2·ClHColor and Shape:NeatMolecular weight:203.67Firocoxib-d4
CAS:Controlled Product<p>Applications Labelled Firocoxib (F356002). A selective cyclooxygenase-2-(COX-2) inhibitor. Anti-inflammatory; analgesic.<br>References McCann, M.E., et al.: Am. J. Vet. Res., 65, 503 (2004),<br></p>Formula:C172H4H16O5SColor and Shape:NeatMolecular weight:340.43Leflunomide
CAS:Controlled Product<p>Applications An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index).This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vrenken, T., et al.: J. Hepatol., 49, 799 (2008), Mazzucco, G., et al.: Clin. Nephrol., 70, 163 (2008), Davies, M., et al.: J. Med. Chem., 52, 2683 (2009),<br></p>Formula:C12H9F3N2O2Color and Shape:NeatMolecular weight:270.211-(4-Fluorophenyl)-3-thiophen-2-yl-1H-pyrazole-5-carboxylic acid
CAS:Purity:98.0%Color and Shape:Solid, Off-white powderMolecular weight:288.29998779296875Hydroxymethoxy-N-desmethyl Toremifene
Formula:C26H28ClNO3Purity:>80%Color and Shape:NeatMolecular weight:437.96
![4-OXO-5-(THIOPHEN-2-YLMETHYL)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE-3-CARBOXYLIC ACID](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF530938.webp&w=3840&q=75)
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![2-{[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-5,5-dimethylcyclohexane-1,3-dione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF094194.webp&w=3840&q=75)
