Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65578 products of "Quinazoline and Quinoline Derivatives"
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4-(1H-Pyrazol-4-yl)quinoline
CAS:Purity:95.0%Color and Shape:Solid, Crystalline PowderMolecular weight:195.22500610351562Tert-Butyl-4-(isoquinolin-5-yl)piperazine-1-carboxylate
CAS:Purity:97%Molecular weight:313.4010009765625Ref: 10-F469542
1gTo inquire2gTo inquire5gTo inquire10gTo inquire100mgTo inquire250mgTo inquire500mgTo inquirePyrimethamine-d3
CAS:Controlled Product<p>Applications Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial.<br>References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983), Leport, C., et al.: Am. J. Med., 84, 94 (1988), McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1998), Plowe, C.V., et al.: Br. Med. J., 328, 545 (2004),<br></p>Formula:C12H10D3ClN4Color and Shape:Off-WhiteMolecular weight:251.734-[4-(4-Chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]-1-(4-fluorophenyl)-1-butanone
CAS:<p>Applications 4-[4-(4-Chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]-1-(4-fluorophenyl)-1-butanone is a dehydrated metabolite of haloperidol that can be biotransfomed by humans to Haloperidol pyridinium (HPP+), a potential neurotoxic found in the brain.<br>References Usuki, E., et. al.: Neurotoxicity Res., 4, 51 (2002)<br></p>Formula:C21H21ClFNOColor and Shape:NeatMolecular weight:357.85Ponazuril
CAS:Controlled Product<p>Applications Antiprotazoal, used to treat Equine Protozoal Myeloencephalitis (EPM).<br>References Mitchell, S., et al.: J. Parasitol., 90, 639 (2004), Didikolu, L., et al.: J. Vet. Pharmacol. Ther., 32, 368 (2009), Martinez-Villalba, A., et al.: Anal. Bioanal. Chem., 397, 2893 (2010),<br></p>Formula:C18H14F3N3O6SColor and Shape:Off WhiteMolecular weight:457.38(R)-Lansoprazole
CAS:<p>Stability Hygroscopic<br>Applications The R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),<br></p>Formula:C16H14F3N3O2SColor and Shape:Off White To Dark BrownMolecular weight:369.36Nicorandil-d4
CAS:Controlled Product<p>Stability Unstable in Solution<br>Applications An antianginal.<br>References Yoneyama, F., et al.: Cardiovasc. Drugs Ther., 4, 1119 (1990), Purcell, H., et al.: Brit. J. Clin. Pract., 47, 150 (1993)<br></p>Formula:C82H4H5N3O4Color and Shape:NeatMolecular weight:215.20N-(3-Chloro-4-(((2-(methylamino)-6-(pyridin-2-yl)pyrimidin-4-yl)amino)methyl)phenyl)methanesulfonamide
CAS:Purity:98.0%Molecular weight:418.8999938964844(3-Amino-pyrrolidin-1-yl)-thiophen-2-yl-methanone hydrochloride
CAS:Purity:95.0%Molecular weight:232.72999572753906Levofloxacin-d3
CAS:Controlled Product<p>Applications Levofloxacin-d3, is the labeled analogue of Levofloxacin (L360000), an antibiotic used against gram-negative organisms.<br>References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),<br></p>Formula:C18H17D3FN3O4Color and Shape:NeatMolecular weight:364.392,6-Dichloro-4-phenyl-quinazoline
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:275.1300048828125(1-(4-Methylphenyl)-3-(4-(methylthio)phenyl)-1H-pyrazol-4-yl)methanol
CAS:Molecular weight:310.4200134277344Gefitinib
CAS:Controlled ProductFormula:C22H24ClFN4O3Color and Shape:White SolidMolecular weight:446.903,4,5-Trimethylpyridin-2-amine
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:136.197998046875Robenacoxib
CAS:<p>Applications A novel COX-2 selective inhibitor, as a nonsteroidal analgesic, anti-inflammatory and antipyretic agent.<br>References McCormack, K., et al.: Drugs, 41, 533 (1991), Giraudel, J., et al.: Br. J. Pharmacol., 146, 642 (2005), Brune, K., et al.: Rheumatology, 46, 911 (2007),<br></p>Formula:C16H13F4NO2Color and Shape:Off-WhiteMolecular weight:327.271-(Morpholin-4-yl)-2-(piperazin-1-yl)ethane-1,2-dione
CAS:Purity:98%Molecular weight:227.264007568359381,2,3,9-Tetrahydro-4H-carbazol-4-one
CAS:Controlled Product<p>Applications A carbazole derivative with antimycobacterial activity.<br>References Romeo, G., et al.: Bioorg. Med. Chem., 14, 5211 (2006),<br></p>Formula:C12H11NOColor and Shape:BeigeMolecular weight:185.22N-(4-((4-Chloro-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)thio)phenyl)cyclopropanecarboxamide
CAS:Purity:95.0%Molecular weight:400.8900146484375Methyl-1-naphthalenemethylamine
CAS:<p>Impurity Terbinafine EP Impurity A; Terbinafine BP Impurity A; Terbinafine USP Related Compound A<br>Applications Terbinafine EP Impurity A. Terbinafine BP Impurity A. Terbinafine USP Related Compound A<br></p>Formula:C12H13NColor and Shape:OrangeMolecular weight:171.24Gefitinib Morpholine N-oxide
CAS:Controlled Product<p>Applications Gefitinib Morpholine N-oxide is the N-oxide derivative of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).<br>References Lynch, T.J., et al.: N. Engl. J. Med., 350, 2129 (2004); Engelman, J.A., et al.: Science, 316, 1039 (2007); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003)<br></p>Formula:C22H24ClFN4O4Color and Shape:White To Off-WhiteMolecular weight:462.90(2-Piperidin-1-ylpyridin-4-yl)methylamine
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:191.27799987792972-(3-Pyridyl)-2-oxazoline
CAS:Controlled Product<p>Applications 2-(3-Pyridyl)-2-oxazoline is an impurity of Nicorandil (N398500). Nicorandil impurity E.<br></p>Formula:C8H8N2OColor and Shape:Off-White To Light YellowMolecular weight:148.165-(Naphthalen-1-yl)-1-phenyl-1H-pyrazole-3-carboxylic acid
CAS:Purity:95.0%Molecular weight:314.3439941406254-Bromoquinoline-6-carbonitrile
CAS:Formula:C10H5BrN2Purity:98%Color and Shape:SolidMolecular weight:233.0682-Hydroxy Felbamate
CAS:<p>Applications A metabolite of the antiepileptic drug Felbamate (F231000).<br>References Yang, J.T. et al.: Drug Metab. Disp., 19, 1126 (1991); Roller, S.G. et al.: Chem. res. Toxicol., 15, 815 (2002);<br></p>Formula:C11H14N2O5Color and Shape:NeatMolecular weight:254.24Hydrodolasetron
CAS:Controlled Product<p>Applications Hydrodolasetron, is the reduced form of Dolasetron (D528500), a specific serotonin (5HT3) receptor antagonist. Antiemetic.<br>References Boeijinga, P.H., et al.: Eur. J. Pharmacol., 219, 9 (1992), Miller, R.C., et al., Drug Dev. Res., 28, 87 (1993), Fauser, A.A., et al.: Eur. J. Cancer, 32, 1523 (1996), Graczyk, S.G., et al.: Anesth. Analg., 84, 325 (1997),<br></p>Formula:C19H22N2O3Color and Shape:White To Off-WhiteMolecular weight:326.39N-pyridin-3-yl-2-(tetrahydro-2H-pyran-4-ylcarbonyl)hydrazinecarbothioamide
Molecular weight:280.3500061035156Tranilast
CAS:Controlled Product<p>Applications Antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.<br>References Shiota, N., et al.: Brit. J. Pharmacol., 159, 626 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Kawabata, Y., et al.: Eur. J. Pharm. Sci., 39, 256 (2010),<br></p>Formula:C18H17NO5Color and Shape:NeatMolecular weight:327.333-Amino-5-(4-phenoxyphenyl)thiophene-2-carboxylic acid methyl ester
CAS:Color and Shape:SolidMolecular weight:325.3800048828125(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
CAS:Purity:95.0%Molecular weight:345.4200134277344Ketoconazole
CAS:Controlled Product<p>Applications Inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor. Inhibitor of exosome secretion.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986); Scientific Reports 8: 8161 (2018)<br></p>Formula:C26H28Cl2N4O4Color and Shape:NeatMolecular weight:531.43Nemadipine B
CAS:Controlled Product<p>Impurity Felodipine EP Impurity C<br>Applications Nemadipine B (Felodipine EP Impurity C) is the diethyl ester analogue analogue of the calcium channel blocker Felodipine (F232375) with antihypertensive activity.<br>References Berntsson, P. et al.: J. Cardio. Pharmacol., 10, S60 (1987); Kwok, T.C. et al.: Nature, 441, 91 (2008);<br></p>Formula:C19H21Cl2NO4Color and Shape:NeatMolecular weight:398.28N-Benzyl Salbutamon Hydrochloride
CAS:Controlled Product<p>Applications N-Benzyl Salbutamon Hydrochloride is an impurity of Albuterol (Salbutamol) (A514500), an β2-adrenoceptor agonist. Bronchodilator; tocolytic.<br>References 1. Collin, D. et al.: J. Med. Chem. 1970 Jul;13(4):674-80.2. Raidal, S. et al.: Vet. J. 2017 Apr;222:22-28.<br></p>Formula:C20H25NO3·ClHColor and Shape:NeatMolecular weight:363.88N-Despropyl-macitentan
CAS:Controlled Product<p>Applications N-Despropyl-macitentan, is an active metabolite which is part of a family of endothelin receptor antagonist that allows for treatment of pulmonary arterial hypertension (PAH)<br>References Atsmon, J., et al.: Clin. Pharmacokinet., 525, 685 (2013); Sidharta, P.N., et al.: Clin. Drug Invest. (2014)<br></p>Formula:C16H14Br2N6O4SColor and Shape:NeatMolecular weight:546.19TERT-BUTYL 3-(THIOPHEN-2-YL)PYRROLIDINE-1-CARBOXYLATE
CAS:Purity:95.0%Molecular weight:253.360000610351562-Acetoxy-N-(2-thiazolyl)benzamide
CAS:Controlled Product<p>Applications 2-Acetoxy-N-(2-thiazolyl)-benzamide is used in the synthesis of thiazolides as novel antiviral agents. Used in the inhibition of hepatitis C virus replication. Nitazoxanide Impurity<br>References Edwards, G. et al.: J. Med. Chem., 54, 8670 (2011);<br></p>Formula:C12H10N2O3SColor and Shape:Off-WhiteMolecular weight:262.28(4-Bromo-5-cyclopropyl-3-trifluoromethyl-pyrazol-1-yl)-acetic acid
CAS:Formula:C9H8BrF3N2O2Purity:95.0%Color and Shape:SolidMolecular weight:313.074
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![(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF448256.webp&w=3840&q=75)
