Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65630 products of "Quinazoline and Quinoline Derivatives"
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cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-Tolylsulfonate
CAS:<p>Impurity Ketoconazole EP Impurity E<br>Applications cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-Tolylsulfonate (Ketoconazole EP Impurity E) is an intermediate in the synthesis of the drug Ketoconazole (K186000).<br>References McManus, O., et al.: Biochemistry, 32, 6128 (1993), Olesen, S., et al.: Eur. J. Pharmacol., 251, 53 (1994), Assano, M., et al.: J. Pharm. Exp. Ther., 275, 775 (1995), Hewawasam, P., et al.: J. Med. Chem., 45, 1487 (2002),<br></p>Formula:C21H20Cl2N2O5SColor and Shape:NeatMolecular weight:483.36Tetramethylurea
CAS:<p>Applications Tetramethylurea is an excellent solvent for organic substances, in particular aromatic compounds.<br>References Lüttringhaus, A., et al.: Angew. Chem. Int. Ed. Engl., 3, 260 (1964)<br></p>Formula:C5H12N2OColor and Shape:NeatMolecular weight:116.16Des [3-(1-Dimethylamino)ethyl] 3-Acetyl Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity C; USP Related Compound D<br>Applications Des [3-(1-dimethylamino)ethyl] 3-acetyl Rivastigmine (Rivastigmine EP Impurity C) is a derivative of Rivastigmine (Tartrate: R541000), and acetylcholinesterase inhibitor that is commonly used to treat dementia associated with Parkinson’s disease and Alzheimer’s disease.<br>References Emre, M., et al.: New. Engl. J. Med., 351, 2509 (2004); Polinsky, R.: Clin. Ther., 20, 634 (1998); Wilkinson, D., et al.: Int. J. Clin. Pract., 56, 441 (2001)<br></p>Formula:C12H15NO3Color and Shape:Off-WhiteMolecular weight:221.25Gleevec-d8 Mesylate (Imatinib-d8 Mesylate)
CAS:Controlled Product<p>Applications A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.<br>References Schindler, T., et al.: Science, 289, 1938 (2000), Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001),<br></p>Formula:C292H8H23N7O·CH4O3SColor and Shape:NeatMolecular weight:597.76(Z)-1,2-Diphenyl-1-(4-hydroxyphenyl)-1-butene (contain up to 10% E-isomer)
CAS:Controlled ProductFormula:C22H20OColor and Shape:NeatMolecular weight:300.394Desisopropyl Atrazine
CAS:Controlled Product<p>Applications A metabolite of Atrazine (ATR) (A794600).<br>References Compton, D., et al.: Eur. J. Pharmacol., 110, 157 (1985), Das, P., et al.: Toxicol. Sci., 59, 127 (2001), Das, P., et al.: Life Sci., 73, 3123 (2003), Coban, A., et al.: J. Neurochem., 100, 1177 (2007),<br></p>Formula:C5H8ClN5Color and Shape:Off-WhiteMolecular weight:173.602-[2-[[4-[(5S)-5-[[[(5-Chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]-acetic Acid Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 2-[2-[[4-[(5S)-5-[[[(5-chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]-acetic Acid Hydrochloride is a metabolite of Rivaroxaban (R538000) which is a novel antithrombotic agent. Rivaroxaban is also a highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005)<br></p>Formula:C19H20ClN3O6S·HClColor and Shape:White Light RedMolecular weight:453.9036466-chloro-2-pyridin-4-ylquinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:284.700012207031251,2,3,4-Tetrahydro-4,8-dihydroxy-2-methyl-isoquinoline
CAS:<p>Impurity Phenylephrine 4,6-DMTQ Impurity (Peak-2)<br>Applications Product formed during the decomposition of Phenylephrine<br>References Millard, B., et al.: J. Pharm. Pharmacol., 25, 24 (1973),<br></p>Formula:C10H13NO2Color and Shape:Light YellowMolecular weight:215.68(E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
CAS:Controlled ProductFormula:C18H15NO4Color and Shape:Light YellowMolecular weight:309.32Olanzapine-d3
CAS:Controlled Product<p>Applications Deuterated Olanzapine, a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity. Antipsychotic.<br>References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)<br></p>Formula:C172H3H17N4SColor and Shape:Yellow To BrownMolecular weight:315.45(3S,3'S)-4,4'-(7-Chloropyrido[2,3-d]pyrimidine-2,4-diyl)bis(3-methylmorpholine)
CAS:Purity:95.0%Molecular weight:363.8500061035156Pentoxifylline-d6
CAS:Controlled Product<p>Applications A labelled metabolite of Pentifylline. Methylxanthine derivative that improves blood flow by decreasing blood viscosity. Phosphodiesterase inhibitor. Inhibits the synthesis of tumor necrosis factor α (TNF-α).<br>References Ward, A., et al.: Drugs, 34, 50 (1987), Samlaska, C.P., et al.: J. Am. Acad. Dermatol., 30, 603 (1994), Poulakis, et al.: Respir. Med., 93, 52 (1999), Reuter, et al.: Am J. Physiol., 277, 854 (1999),<br></p>Formula:C132H6H12N4O3Color and Shape:NeatMolecular weight:284.342-(2,6-Dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Purity:97.0%Molecular weight:288.3599853515625(R)-4-Hydroxy Propranolol Hydrobromide
CAS:Controlled Product<p>Applications The main metabolite of (R)-Propranolol.<br>References Shwed, J., et al.: Xenobiotica, 22, 973 (1992), Fujita, K., et al.: Biol. Pharm. Bull., 22, 446 (1999), Walle, U., et al.: Drug Metab. Dispos., 30, 564 (2002),<br></p>Formula:C16H21NO3·HBrColor and Shape:NeatMolecular weight:356.25Desfluoro Ezetimibe
CAS:Controlled Product<p>Impurity Ezetimibe Desfluoroaniline Analog (USP)<br>Stability Hygroscopic<br>Applications An impurity of the cholesterol absorption inhibitor Ezetimibe (E975000). Ezetimibe Desfluoroaniline Analog (USP).<br>References Anon.: IP.com J., 7, 4 (2007);<br></p>Formula:C24H22FNO3Color and Shape:White To Off-WhiteMolecular weight:391.435-Chloro-N-cyclohexylpentanamide
CAS:<p>Stability Hygroscopic<br>Applications 5-Chloro-N-cyclohexylpentanamide (cas# 15865-18-6) is a compound useful in organic synthesis.<br></p>Formula:C11H20ClNOColor and Shape:NeatMolecular weight:217.7363-Picoline
CAS:Controlled Product<p>Applications A useful precursor to agrochemicals and antidotes for organophosphate poisoning.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Qiao, L., et al.: Bioorg. Med. Chem. Lett., 19, 6122 (2009), Giri, A., et al.: Food Chem., 120, 621 (2010), Farrer, N., et al.: Chem. Res. Toxicol., 23, 413 (2010),<br></p>Formula:C6H7NColor and Shape:ColourlessMolecular weight:93.13Genfatinib-d3 (Imatinib-d3)
CAS:Controlled Product<p>Applications Genfatinib-d3 (Imatinib-d3) is the labeled analogue of Genfatinib, a treatment of chronic myeloid leukemia (CML). It is a COVID19-related research product.<br>References Helmann, R., et. al.: J. Clin. Oncol., 32, 415 (2014)<br></p>Formula:C29D3H28N7OColor and Shape:NeatMolecular weight:496.624-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide
CAS:Purity:99.0%Color and Shape:SolidMolecular weight:482.82000732421875Ref: 10-F361865
1gTo inquire5gTo inquire10gTo inquire25gTo inquire10mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquire500mgTo inquireTofacitinib impurity N
CAS:Controlled Product<p>Impurity Tofacitinib Impurity (T528000)<br>Applications Tofacitinib impurity N is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.<br>References Jiang, J., et. al.: J. med. Chem., 51, 8012 (2008)<br></p>Formula:C13H19N5Color and Shape:NeatMolecular weight:245.327-(Benzyloxy)quinolin-4-ol
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:251.285003662109383-Hydroxy-5-methylisoxazole
CAS:Controlled ProductFormula:C4H5NO2Color and Shape:White To OrangeMolecular weight:99.09N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycine
CAS:Controlled Product<p>Applications N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycine, is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formula:C12H19NO3Color and Shape:NeatMolecular weight:225.28[2-(1H-indol-3-yl)ethyl](3-pyridinylmethyl)amine hydrobromide
CAS:Purity:95.0%Molecular weight:332.244995117187511-Morpholino-dibenzo[b,f][1,4]thiazepine
CAS:Controlled Product<p>Applications 11-Morpholino-dibenzo[b,f][1,4]thiazepine is part of a group of 11-(substituted-amino)dibenzo[b,f][1,4]thiazepine compounds that have analgesic and sedative properties.<br>References Schmutz, J. & Hunziker, F.: Patentschrift (Switz.), 7pp. (1969)<br></p>Formula:C17H16N2OSColor and Shape:NeatMolecular weight:296.39Linuron-d6
CAS:Controlled Product<p>Applications Labelled analog of a restricted use pesticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bradford, D., et al.: Environ. Sci. Technol., 44, 4609 (2010), Trtic-Petrovic, T., et al.: Anal. Bioanal. Chem., 397, 2233 (2010), Stewart, C., et al.: Weed Biol. Man., 10, 40 (2010),<br></p>Formula:C92H6H4Cl2N2O2Color and Shape:Off-WhiteMolecular weight:255.136-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-((1-methylpiperidin-4-yl)amino)quinazolin-7-ol (trihydrochloride)
Purity:98%Molecular weight:509.97-chloro-8-methyl-2-pyridin-4-ylquinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:298.7300109863281Flubendazole alcohol
CAS:Controlled Product<p>Applications Flubendazole alcohol is a metabolite of the anthelmintic Flubendazole (F418500).<br>References Meuldermans, W., et al.: Eur. J. Drug Metab. Pharmacokinet., 1, 35 (1976), Dusi, G., et al.: J. Pharmaceut. Biomed. Anal., 38, 375 (2005), Cvilink, V., et al.: Vet. Parasitol., 151, 242 (2008),<br></p>Formula:C16H14FN3O3Color and Shape:White To Off-WhiteMolecular weight:315.301-(5-(BENZYLOXY)PYRIDIN-2-YL)CYCLOPROPANECARBOXYLIC ACID
Purity:95.0%Molecular weight:269.299987792968752-(5-amino-3-phenyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4(3H)-one
CAS:Purity:95.0%Molecular weight:267.2919921875(S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(pyridin-4-yl)butanoic acid
CAS:Purity:95+%Molecular weight:402.45001220703125Ethyl fluoroacetate
CAS:Controlled Product<p>Applications Ethyl fluoroacetate is an inhibitor of insect juvenile hormone biosynthesis. It also shows toxic effects against Vibrio fischeri.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Quistad, Gary B., et al.: J. of Agri. and Food Chem., 30(6), 1151-4 (1982);Dawson, D. A., et al.: Archives of Envir. Contam. and Tox., 66(2), 248-258 (2014)<br></p>Formula:C4H7FO2Color and Shape:NeatMolecular weight:106.1rac Penbutolol-d9
CAS:Controlled Product<p>Applications Labelled Penbutolol (P220500). A β-adrenoceptor antagonist. Antihypertensive.<br>References Armstrong, D., et al.: Anal. Chem., 66, 1473 (1994), Kato, M., et al.: J. Pharm. Biomed. Anal., 30, 1845 (2003),<br></p>Formula:C18H20D9NO2Color and Shape:White To Off-WhiteMolecular weight:300.48[2-(4-Methyl-2-phenylpiperazin-1-yl)phenyl]methanol
CAS:Controlled Product<p>Applications [2-(4-Methyl-2-phenylpiperazin-1-yl)phenyl]methanol is used in the preparation of azepine.<br>References Lypacewicz, Maria K. et al., Pol.(1998);<br></p>Formula:C18H22N2OColor and Shape:White To Light BeigeMolecular weight:282.3810,11-Dihydro-11-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]dibenzo[b,f][1,4]thiazepin-11-ol
CAS:Controlled Product<p>Applications Quetol is an impurity of Quetiapine(Q509900) a dibenzothiazepine antipsychotic commonly used as monotherapy for patients with major depressive disorder and schizophrenia.<br>References Cutler, A., et al.: J. Clin. Psych., 70, 526 (2009); Kapur, S., et al.: Arch. Gen. Psych., 57, 553 (2000); Peuskens, J. & Link, C.: Acta. Psych. Scand., 96, 265 (1997)<br></p>Formula:C21H27N3O3SColor and Shape:YellowMolecular weight:401.522Tenoxicam
CAS:Controlled Product<p>Applications Nonsteroidal anti-inflamatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bird, H.A., et al.: Curr. Med. Res. Opin., 8, 9 (1982), Gonzalez, J.P., et al.: Drugs, 34, 289 (1987), Al-Obaid, A.M., et al.: Anal. Profiles Drug Subs. Excip., 22, 431 (1993),<br></p>Formula:C13H11N3O4S2Color and Shape:NeatMolecular weight:337.37Olaquindox
CAS:<p>Applications A growth stimulant.<br>References Barber, R.S., et al.: Anim. Feed Sci. Technol., 4, 117 (1979), Kwaga, J., et al.: Antimicrob. Agents Chemother., 34, 2423 (1990), Hugot, J., et al.: Lancet, 362, 2012 (2003),<br></p>Formula:C12H13N3O4Color and Shape:NeatMolecular weight:263.25Desamino Imiquimod N-Oxide
CAS:Controlled Product<p>Impurity Imiquimod USP Related Compound B<br>Applications Desamino Imiquimod N-Oxide (Imiquimod USP Related Compound B) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.<br>References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998); Gerster, J. et al.: J. Med. Chem., 48, 3481 (2005);<br></p>Formula:C14H15N3OColor and Shape:NeatMolecular weight:241.29
![cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-Tolylsulfonate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD435718.webp&w=3840&q=75)
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![(3S,3'S)-4,4'-(7-Chloropyrido[2,3-d]pyrimidine-2,4-diyl)bis(3-methylmorpholine)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF229684.webp&w=3840&q=75)
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![[2-(4-Methyl-2-phenylpiperazin-1-yl)phenyl]methanol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM563455.webp&w=3840&q=75)
![10,11-Dihydro-11-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]dibenzo[b,f][1,4]thiazepin-11-ol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FQ510033.webp&w=3840&q=75)
