
Steroids and Derivatives
Found 4966 products of "Steroids and Derivatives"
3Beta-Hydroxydesogestrel
CAS:Controlled ProductStability Light Sensitive
Applications 3β-Hydroxydesogestrel is a metabolite of Desogestrel (D296875), a progestogen with low androgenic potency.
References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)Formula:C22H30O2Color and Shape:WhiteMolecular weight:326.477b-Fulvestrant
CAS:Controlled ProductImpurity Fulvestrant EP Impurity A
Applications Fulvestrant (F862500) impurity A. The S-isomer of Fulvestrant.
References Sharman, G.J., et al.: Mag. Resonance Chem., 39, 549 (2001),Formula:C32H47F5O3SColor and Shape:Light Brown SolidMolecular weight:606.77Didemethyl Mifepristone
CAS:Controlled ProductApplications A metabolite of Mifepristone.
References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),Formula:C27H31NO2Color and Shape:NeatMolecular weight:401.54Spironolactone-d7 (Major)
CAS:Controlled ProductApplications It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome. A representative lot was 19% d3; 47% d6; 12% d7; 7% d8; 3% d9; 3% d10 and 8% d11.
References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975),Formula:C24H25D7O4SColor and Shape:NeatMolecular weight:423.62Norethindrone Acetate
CAS:Applications Progesteron. Norethindrone and acetate in combination with estrogen as contraceptive (oral). It is reasonably anticipated to be a human carcinogen.
References Schroff, A. P., et al.: Anal. Profiles Drug Subs., 4, 268 (1975), Singh, H., et al.: Am. J. Obstet. Gynecol., 135, 409 (1979), Toews, M., et al.: Curr. Ther. Res, 41, 509 (1987),Formula:C22H28O3Color and Shape:White To Off-WhiteMolecular weight:340.464-Hydroxy Atorvastatin Hemicalcium Salt
CAS:Applications 4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References Smith, S. et al.: Am. J. Cardiol., 80, 10H (1997); Jacobsen, W. et al.: Drug Metab. Dispos., 28, 1369 (2000); Istvan, E. et al.: Science, 292, 1160 (2001); Tabernero, L. et al.: J. Biol. Chem., 278, 19933 (2003); Bratton, L. et al.: Bioorg. Med. Chem., 15, 5576 (2007);Formula:C66H68CaF2N4O12Purity:>90%Color and Shape:NeatMolecular weight:1187.3417-Epiestriol-d5
CAS:Controlled ProductApplications A labelled metabolite of Estradiol (E888000).
References Marrian, B., et al.: Biochem. J., 59, 136 (1955), Dietel, M., et al.: Cancer Res., 50, 6100 (1990), Schumacher, G., et al.: Clin. Cancer Res., 5, 493 (1999), Robert, J., et al.: J. Med. Chem., 46, 4805 (2003),Formula:C18H19D5O3Color and Shape:NeatMolecular weight:293.41Pregna-4,9(11)-diene-3,20-dione (90%)
CAS:Controlled ProductApplications Pregna-4,9(11)-diene-3,20-dione is a Progesterone (P755900) impurity, a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.
References Thomas, P. et al.: Endocrinol., 148, 705 (2007); Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),Formula:C21H28O2Purity:90%Color and Shape:NeatMolecular weight:312.45Ciclesonide-d7
CAS:Controlled ProductApplications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.
References ukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).Formula:C32H37D7O7Color and Shape:NeatMolecular weight:547.73Cyproterone
CAS:Controlled ProductImpurity Cyproterone Acetate EP Impurity F
Applications Cyproterone (Cyproterone Acetate EP Impurity F) is an antiandrogen, suppresses Testosterone and its metabolites. Derivatives of Cyproterone are administered to patients suffering from hypersexuality and to help facilitate the sexual transformation of male-to-female transsexuals.
References Gracia, T., et al.: Toxicol. App. Pharmacol., 225, 142 (2007), Ahlin, G., et al.: J. Med. Chem., 51, 5932 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2010),Formula:C22H27ClO3Color and Shape:Off White SolidMolecular weight:374.9Testosterone-d3 β-D-Glucuronide Monosodium Salt
CAS:Controlled ProductApplications Labelled Metabolite of Testosterone (T155000).
References Shibata, N., et al.: Biochem. J., 368, 783 (2002), Sonneveld, E., et al.: Toxicol. Sci., 83, 136 (2005), Schulze, J., et al.: J. Clin. Endocrinol. Metab., 93, 2500 (2008), Sten, T., et al.: DrugFormula:C25H32D3NaO8Color and Shape:Off-WhiteMolecular weight:489.55Betamethasone 17-Propionate-d5
CAS:Controlled ProductFormula:C25H28D5FO6Color and Shape:NeatMolecular weight:453.56Estrone 3-O-Sulfamate
CAS:Controlled ProductApplications A potent inhibitor of estrone sulfatase. Inhibits estrone sulfatase >99% at 0.1uM in intact MCF-7 cells, IC50=65pM.
References Woo, L.W., et al.: J. Med. Chem., 41, 1068 (1998)Formula:C18H23NO4SColor and Shape:NeatMolecular weight:349.44Digoxigenin Bisdigitoxoside
CAS:Controlled ProductStability Hygroscopic
Applications A metabolite of Digoxin (Dx) (D446575).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),Formula:C35H54O11Color and Shape:Off White SolidMolecular weight:650.8Tixocortol (>90%)
CAS:Controlled ProductStability Hygroscopic
Applications Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling.
References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),Formula:C21H30O4SPurity:>90%Color and Shape:NeatMolecular weight:378.5317-Desacetyl Norgestimate-d6 (Major)
CAS:Controlled ProductApplications A labelled metabolite of Norgestimate.
References Phillips, A., et al.: Steroids, 55, 373 (1990)Formula:C21D6H23NO2Color and Shape:NeatMolecular weight:333.516a,17-[(1RS)-Butylidenebis(oxy)]-11b-hydroxy-17-(hydroxymethyl)-D-homoandrosta-1,4-diene-3,17a-dione (Mixture of Diastereomers)
CAS:Controlled ProductImpurity Budesonide EP Impurity C, Budesonide Impurity C,
Applications 16α,17-[(1RS)-butylidenebis(oxy)]-11β-hydroxy-17-(hydroxymethyl)-D-homoandrosta-1,4-diene-3,17a-dione (Budesonide EP Impurity C) is an impurity of Budesonide (B689490), an antiinflammatory agent.
References Ferraboschi, P. et al.: J. Pharm. Biomed. Anal., 47, 636 (2008);Formula:C25H34O6Color and Shape:WhiteMolecular weight:430.53Desonide 21-Acetate
CAS:Controlled ProductStability Hygroscopic
Applications Desonide 21-Acetate is a reactant in the synthesis of 7α-halogenocorticosteroids with anti-inflammatory activity.
References De, K., et. al.: J. Indian Chem. Soc., 79, 513 (2002)Formula:C26H34O7Color and Shape:NeatMolecular weight:458.542-Hydroxy Atorvastatin Calcium Salt
CAS:Controlled ProductApplications di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)Formula:C66H68CaF2N4O12Color and Shape:White To YellowMolecular weight:1187.3521-Dehydrocorticosterone (mixture of the aldehyde and the hydrated form)
CAS:Formula:C21H28O4Color and Shape:NeatMolecular weight:344.44Promestriene
CAS:Controlled ProductApplications A synthetic diethyl-ether of Estradiol with no distal hormonal effects, in patients undergoing surgical correction for stress urinary incontinence (SUI).
References Kelleher, C., et al.: Br. J. Obstet. Gynaecol., 104, 1374 (1997), Deffieux, X., et al.: J. Gynecol. Obstet. Biol. Reprod., 35, 678 (2006),Formula:C22H32O2Color and Shape:NeatMolecular weight:328.49Ciclesonide 22S-Epimer
CAS:Controlled ProductFormula:C32H44O7Color and Shape:NeatMolecular weight:540.688Estrone b-D-Glucuronide Sodium Salt (>97% by HPLC)
CAS:Controlled ProductApplications A metabolite of 17β -Estradiol (E888000).
References Cekan, S., et al.: J. Steroid Biochem., 27, 95 (1989), Martin, R., et al.: Clin. Chem., 46, 100 (2000), Blackwell, L., et al.: Steroids, 68, 465 (2003)Formula:C24H29O8·NaPurity:>97% by HPLCColor and Shape:White To Light BrownMolecular weight:468.475,6-trans Travoprost
CAS:Applications An 5,6-trans isomeric impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600).
Formula:C26H35F3O6Color and Shape:NeatMolecular weight:500.55Protodioscin
CAS:Applications Protodioscin is a steroidal saponin compound found in a number of plant species. It is known to be the active component of the herbal aphrodisiac plant Tribulus terrestris. It has also shown to produce significant increases in the levels of the hormonal levels in animal studies.
References Gauthaman, K., et al.: Inter. J. Phytother. Phytopharm., 15, 44 (2008); Ganzera, M., et al.: J. Pharmac. Sci., 90(11), 1752 (2001);Formula:C51H84O22Color and Shape:Off-White To Light BeigeMolecular weight:1049.2Ref: 10-F979169
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquire11Beta,21-dihydroxypregna-1,4,16-triene-3,20-dione
CAS:Applications 11β,21-dihydroxypregna-1,4,16-triene-3,20-dione is a derivative of Prednisolone (P703740) and an intermediate in the synthesis of isoxazolinopregnadienes which exhibit anti-inflammatory activity.
References Khalil, M.A., et al.: Med. Chem. Res., 6, 52 (1996); Kwon, T., et al.: J. Med. Chem., 38, 1048 (1995)Formula:C21H26O4Color and Shape:NeatMolecular weight:342.43Dexamethasone 21-Phosphate Dimer Sodium Salt
CAS:Controlled ProductStability Hygroscopic
Applications Dexamethasone 21-Phosphate Dimer is a derivative of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.
References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)Formula:C44H56F2NaO12PColor and Shape:White SolidMolecular weight:868.8717-Epiestriol
CAS:Controlled ProductImpurity Estriol EP Impurity E
Applications 17-Epiestriol (Estriol EP Impurity E) is a metabolite of Estradiol.
References Marrian, B., et al.: Biochem. J., 59, 136 (1955), Dietel, M., et al.: Cancer Res., 50, 6100 (1990), Schumacher, G., et al.: Clin. Cancer Res., 5, 493 (1999), Robert, J., et al.: J. Med. Chem., 46, 4805 (2003),Formula:C18H24O3Color and Shape:White To Light RedMolecular weight:288.38Andarine
CAS:Controlled ProductApplications It is a potent and tissue-selective androgen receptor modulator (SARM) used as antiosteoporotic agent.
References Samnegard, E., et al.: Bone, 28, 414 (2001), Hanada, K., et al.: Biol. Pharm. Bull., 26, 1563 (2003), Kearbey, J., et al.: Xenobiotica, 34, 273 (2004), Kearbey, J., et al.: Xenobiotica, 34, 273 (2004), Kearbey, J., et al.: Pharm. Res., 24, 328 (2007),Formula:C19H18F3N3O6Color and Shape:Light YellowMolecular weight:441.36Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate
CAS:Controlled ProductImpurity Dutateride EP Impurity C
Applications Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate (Dutateride EP Impurity C) is a compound synthesized in the production of azasteroids. Used in the inhibition of 5α-reductase and of androgen receptor binding, both major effecters in the male hormonal system.
References Ramusson, G. et al.: J. Med. Chem., 29, 2298 (1986);Formula:C21H31NO3Color and Shape:White To Off-WhiteMolecular weight:345.48Digoxin
CAS:Controlled ProductApplications Cardiotonic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Aronson, J.K., et al.: Clin. Pharmacokinet, 5,137 (1980), Foss, P.R.B., Anal. Profiles Drug Subs., 9, 207 (1980),Formula:C41H64O14Color and Shape:WhiteMolecular weight:780.94Androst-4-ene-3,6,17-trione
CAS:Controlled ProductApplications An aromatase inhibitor.
References Aello, A., et al.: J. Nat. Prod., 54, 281 (1991), Salaja, B.A., et al.: Steroids, 59, 330 (1994), Hunter, A.C., et al.: J. Steroid Biochem. Mol. Biol., 87, 301 (2003),Formula:C19H24O3Color and Shape:NeatMolecular weight:300.3915-Keto Latanoprost
CAS:Applications 15-Keto Latanoprost is a metabolite of Latanoprost (L177280).
References Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998), Watson, P., et al.: Drugs Today, 35, 449 (1999),Formula:C23H30O5Color and Shape:NeatMolecular weight:386.4817,21-Dihydroxy-16a-methylpregna-1,4,9(11)-triene-3,20-dione 21-Acetate
CAS:Controlled ProductApplications 17,21-Dihydroxy-16α-methylpregna-1,4,9(11)-triene-3,20-dione 21-Acetate is an intermediate in the synthesis of Mometasone Furoate (M490000), a tropical corticosteroid used as an anti-inflammatory agent.
References Spangler, M., et al.: Chromatograph., 54, 329 (2001); Reeves, E.K., et al.: Bioorg. Med. Chem., 21, 2241 (2013);Formula:C24H30O5Color and Shape:White To Light YellowMolecular weight:398.4921-Deoxy Cortisone
CAS:Controlled ProductApplications A Cortisone derivative, a glucocorticoid.
References Mickelson, K., et al.: Biochemistry, 20, 6211 (1981), Westphal, U., et al.: J. Steroid Biochem., 19, 1 (1983),Formula:C21H28O4Color and Shape:NeatMolecular weight:344.446β-Hydroxy Norethindrone Acetate
CAS:Controlled ProductImpurity Norethindrone Acetate EP Impurity F
Applications 6β-Hydroxy Norethindrone Acetate (Norethindrone Acetate EP Impurity F) is an oxidative product of the drug Norethindrone (N676000). Norethindrone impurity.
References Reif, V., et al.: Pharmaceutical Res., 4, 54 (1987), Rao, P., et al.: Steroids, 59, 621 (1994),Formula:C22H28O4Color and Shape:Off-WhiteMolecular weight:356.46Estrone
CAS:Controlled ProductImpurity Estradiol EP Impurity A/ Ethinylestradiol EP Impurity C
Applications Estrone is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.Formula:C18H22O2Color and Shape:White To Off-WhiteMolecular weight:270.37Norgestrel-d6 (Major)
CAS:Controlled ProductApplications Labelled Norgestrel. It is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.
References Sopirak, A.M., et al.: Anal. Profiles Drug Subs., 4, 294 (1975), Dunson, T.R., et al.: Contraception, 48, 109 (1993),Formula:C21H22D6O2Color and Shape:White To Light YellowMolecular weight:318.49Estriol Methyl Ether
CAS:Impurity Estriol EP Impurity C
Applications Estriol Methyl Ether (Estriol EP Impurity C) is a metabolite (1,2) of Estriol (E888960), which is a produced naturally and also a metabolite of Estradiol (E888000). Estriol is a GPR3 antagonist in estrogen receptor-negative breast cancer cells displaying anti-proliferative effects (3).
References 1. Marrian, G. et al.: Biochem. J. 1929;23(5):1090-8.2. Rogerson, B. et al.: Arch. Biochem. Biophys. 1986 Oct;250(1):70-85.3. Lappano, R. et al.: Mol Cell Endocrinol. 2010 May 14;320(1-2):162-70.Formula:C19H26O3Color and Shape:NeatMolecular weight:302.41Isofenphos-oxon
CAS:Controlled ProductApplications Calcipotriol Monohydrate is a synthetic derivative of calcitriol, which is a biologically active form of Vitamin D3 (1). Calcipotriol Monohydrate can be used to treat psoriasis (2).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Kim, D. H., et al.: Ann Dermatol. 24, 341 (2012) (2) Queille-Roussel, C., et al.: Clin Drug Investig (2016)Formula:C27H40O3·H2OColor and Shape:NeatMolecular weight:430.624-Hydroxy Estradiol 1-N7-Guanine
CAS:Controlled ProductApplications 4-Hydroxy Estradiol 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.
References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),Formula:C23H27N5O4Color and Shape:NeatMolecular weight:437.49E,E-Dienestrol-d6
Controlled ProductFormula:C18H12D6O2Color and Shape:Light Beige To BrownMolecular weight:272.3716Alpha-Methyl-11-oxo Prednisolone
CAS:Controlled ProductApplications A 16α-substituted Prednisolone as potent topical antiinflammatory agent.
References Lutsky, B.N., et al.: Arzneim.-Forsch., 29, 1662 (1979),Formula:C22H28O5Color and Shape:White SolidMolecular weight:372.45Desonide-13C3
CAS:Controlled ProductApplications Anti-inflammatory.
References Phillips, et al.: Toxicol. Appl. Pharmacol., 20, 522 (1971), Sanen, F.J., et al.: Int. J. Clin. Pharmacol. Biopharm., 12, 174 (1975), Tarayre, J.P., et al.: Pharmacol., 19, 323 (1979).Formula:C2113C3H32O6Color and Shape:NeatMolecular weight:419.494-Hydroxyestradiol 4-O-β-D-Glucuronide Sodium Salt
CAS:Controlled ProductStability Hygroscopic
Applications 4-Hydroxyestradiol 4-O-β-D-Glucuronide Sodium Salt, is a glucuronide derivative of 4-Hydroxy-17β-estradiol (H941895); a metabolite of Estradiol (E888000) which is the major estrogen secreted by the premenopausal ovary.
References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985); Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991); Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998); Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000); Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986); Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987)Formula:C24H32O9•xNaColor and Shape:NeatMolecular weight:464.51

