Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Found 79171 products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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Solifenacin EP Impurity F (Succinate Salt)
CAS:Formula:C23H26N2O2C4H6O4Molecular weight:362.47 : 118.09(3R,4E,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[N-methyl(N-methylsulfonyl)amino]-pyrimidin-5-yl]-3-hydroxy-4,6-heptadienoic Acid Calcium Salt
Formula:(C22H25FN3O5S)CaMolecular weight:2(563.5) : 40.084-amino-N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)benzenesulfonamide
CAS:Formula:C10H10N4O4SMolecular weight:282.27Glyoxal-bis-2,4-DNPH
CAS:Controlled ProductFormula:C14H10N8O8Color and Shape:Dark OrangeMolecular weight:418.283-Hydroxy-1-methylpyridinium Iodide
CAS:Controlled ProductFormula:C6H8NO·IColor and Shape:NeatMolecular weight:237.044,5,6,7-Tetrahydro-5-(triphenylmethyl)thieno[3,2-c]pyridine
CAS:Controlled Product<p>Applications 4,5,6,7-Tetrahydro-5-(triphenylmethyl)thieno[3,2-c]pyridine (cas# 109904-25-8) is a compound useful in organic synthesis.<br></p>Formula:C26H23NSColor and Shape:NeatMolecular weight:381.533-Hydroxypyridine
CAS:Controlled ProductFormula:C5H5NOColor and Shape:White To Light BeigeMolecular weight:95.102-(2-Aminoethylamino)ethanol
CAS:Controlled Product<p>Applications 2-(2-Aminoethylamino)ethanol is a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Its used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013);<br></p>Formula:C4H12N2OColor and Shape:NeatMolecular weight:104.15097-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide
CAS:Controlled Product<p>Applications 7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.<br>References Rodgers, T. et al.: J. Med. Chem., 20, 591 (1977); Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);<br></p>Formula:C19H22BrNO4S2Color and Shape:NeatMolecular weight:472.42Methyl Acetoacetate
CAS:Controlled Product<p>Applications 3-Oxobutanoic Acid Methyl Ester is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.<br>References Ranu, B. et al.: J. Org. Chem. 65, 6270 (2000); Lu, J. et al.: Tetrahedron Lett., 41, 9075 (2000); Lu, J. et al.: Synlett., 1, 63 (2000);<br></p>Formula:C5H8O3Color and Shape:NeatMolecular weight:116.125-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pentanoic Acid
CAS:<p>Applications Apixaban Open chain Acid Is an open ring impurity of Apixaban (A726700). Apixaben is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Formula:C25H27N5O5Color and Shape:Light YellowMolecular weight:477.51Dichloronitromethane
CAS:Formula:CHCl2NO2Color and Shape:Colourless to Pale Yellow OilMolecular weight:129.93Trandolaprilat Monohydrate
CAS:<p>Applications A metabolite of Trandolapril, an antihypertensive.<br>References Blankley, C.J., et al.: J. Med. Chem., 30, 992 (1987)<br></p>Formula:C22H30N2O5·H2OColor and Shape:Off White PowderMolecular weight:420.50FK-506-13C,D2 (Major) (Tacrolimus) (>85%)
CAS:Controlled ProductFormula:CC43D2H67NO12Purity:>85%Color and Shape:NeatMolecular weight:807.02A77 1726 (E/Z) Mixture
CAS:Controlled Product<p>Impurity Leflunomide USP Related Compound B<br>Applications rac A77 1726 is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. The second Phase III study evaluating the efficacy of Genzyme’s teriflunomide therapy against relapsing forms of multiple sclerosis found the once-daily oral drug to be no less effective than injectable interferon beta 1a (Rebif®). Leflunomide USP Related Compound B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)<br></p>Formula:C12H9F3N2O2Color and Shape:NeatMolecular weight:270.21Rivaroxaban
CAS:<p>Applications A novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C19H18ClN3O5SColor and Shape:White To BeigeMolecular weight:435.88Tacrolimus Hydrate
CAS:<p>Applications Tacrolimus Hydrate is a disease-modifying antirheumatic drugs (DMARDs)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ogasawara, M., et al.: Mod. Rheumatol., 22, 831-836 (2012)<br></p>Formula:C44H69NO12·H2OColor and Shape:NeatMolecular weight:822.03Macitentan
CAS:Controlled Product<p>Applications Macitentan, is an orally active endothelin receptor antagonist used for pulmonary arterial hypertension.<br>References Emoto, N. Ensho to Men'eki, 20, 487 (2012);<br></p>Formula:C19H20Br2N6O4SColor and Shape:White To Off-WhiteMolecular weight:588.27Ramipril-d3
CAS:Controlled Product<p>Applications A labelled antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite.<br>References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984), Ruggenenti, P., et al.: Lancet, 352, (1998), Bosch, J., et al.: Br. Med. J., 324, 1 (2002),<br></p>Formula:C23H29D3N2O5Color and Shape:NeatMolecular weight:416.51Trandolapril
CAS:Controlled Product<p>Applications An antihypertensive. Angiotensin converting enzyme (ACE) inhibitor.<br>References Brown, N.L., et al.: Eur. J. Pharmacol., 148, 79 (1988), Kober, L., et al.: N. Engl. J. Med., 333, 1670 (1995), Malik, R.A., et al.: Lancet, 352, 1978 (1998)<br></p>Formula:C24H34N2O5Color and Shape:NeatMolecular weight:430.54Edoxaban-d6
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Edoxaban-d6 is the isotope labelled analog of Edoxaban (E555520); an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Formula:C24H24D6ClN7O4SColor and Shape:Light Beige To Light BrownMolecular weight:554.094-(3-Aminophenyl)-3-morpholinone
CAS:Controlled Product<p>Applications 4-(3-Aminophenyl)-3-morpholinone is an intermediate during the preparation of imidazothiazoles as protein kinase inhibitors for treating cancers.<br>References Bamaung, N., et al.: PCT Int. Appl. (2009), WO 2009070516 A1 20090604.<br></p>Formula:C10H12N2O2Color and Shape:NeatMolecular weight:192.214Bimatoprost
CAS:<p>Stability Light Sensitive<br>Applications Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α.<br>References Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001), Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003), Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),<br></p>Formula:C25H37NO4Color and Shape:WhiteMolecular weight:415.57Repaglinide-ethyl-d5
CAS:Controlled Product<p>Applications Deuterated Repaglinide, a non-sulfonylurea oral hypoglycemic agent which is used as an antidiabetic.<br>References Wolffenbuttel, B.H.R., et al.: Eur. J. Clin. Pharmacol., 45, 113 (1993), Ampudia-Blasco, F.J., et al.: Diabetologia, 37, 703 (1994),<br></p>Formula:C272H5H31N2O4Color and Shape:White SolidMolecular weight:457.62Ethyl 2-Chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate
CAS:Controlled Product<p>Applications Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (cas# 27143-07-3) is a useful research chemical.<br></p>Formula:C11H13N2O3ClColor and Shape:NeatMolecular weight:256.68Diclofenac Epolamine
CAS:<p>Stability Hygroscopic<br>Applications Diclofenac Epolamine is a diclofenac salt with greater water solubility and better cutaneous absorption properties than other commonly used forms of the drug. Diclofenac, a non-steroidal anti-inflammatory drugs (NSAIDs), is the mainstay of analgesic and anti-inflammatory treatment in dentistry.<br>References Serafini, G., et al.: Clin. Drug Invest., 32, 41 (2012); Fini, A., et al.: Eur. J. Pharm. Biopharm., 38, 66 (1992)<br></p>Formula:C14H11Cl2NO2·C6H13NOColor and Shape:NeatMolecular weight:411.32Iomeprol-d3
CAS:Controlled Product<p>Applications Diagnostic aid (radiopaque medium).<br>References Gallotti, A., et al.: Eur. J. Radiol., 18, Suppl 1 S1(1994), Morisetti, A., et al.: Eur. J. Radiol., 18, Suppl 1 S21(1994).<br></p>Formula:C17H19D3I3N3O8Color and Shape:Off-WhiteMolecular weight:780.10Argatroban monohydrate
CAS:Controlled ProductFormula:C23H36N6O5S·H2OColor and Shape:NeatMolecular weight:526.65Probenecid-d14
CAS:Controlled Product<p>Applications Uricosuric.<br>References McKinney, S.E., et al.: J. Pharmacol. Exp. Ther., 102, 208 (1951), Israili, Z.H., et al.: J. Med. Chem., 15, 709 (1972), Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 10, 639 (1981), Cunningham, R.F., et al.: Clin. Pharmacokinet., 6, 135 (1981),<br></p>Formula:C13D14H5NO4SColor and Shape:NeatMolecular weight:299.45Latanoprost
CAS:<p>Applications Prostaglandin analog, used to treat glaucoma and other degenerative diseases of the eye.<br>References Rhee, D.J., et al.: Clinic. Ophthalmol., 2, 313 (2008), Hernandez, M., et al.: Exp. Eye Res., 86, 798 (2008), Nagata, T., et al.: J. Pharmacol. Sci., 106, 423 (2008), Ikeda, Y., et al.: J. Ocular Pharmacol. Ther., 24, 230 (2008),<br></p>Formula:C26H40O5Color and Shape:Light YellowMolecular weight:432.59Dofetilide N-Oxide
CAS:Controlled ProductFormula:C19H27N3O6S2Color and Shape:NeatMolecular weight:457.56Ivermectin
CAS:Controlled Product<p>Applications Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Anthelmintic (Onchocerca).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);<br></p>Formula:C48H74O14·C47H72O14Color and Shape:White To Off-WhiteMolecular weight:1736.16Repaglinide Acyl-β-D-glucuronide
CAS:<p>Applications A metabolite of Repaglinide (M7).<br></p>Formula:C33H44N2O10Color and Shape:NeatMolecular weight:628.71
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