Sulfonamides and Derivatives
Sulphonamides are compounds that contain a sulphonamide functional group (-SO₂NH₂), where a sulphur atom is bonded to an amino group. They were among the first synthetic antibiotics used in medicine, inhibiting folic acid synthesis in bacteria, which gives them antimicrobial properties. They are mainly used to treat bacterial infections, although their use has declined due to antimicrobial resistance. In addition to their use as antibiotics, sulphonamides also have applications in the treatment of diseases such as malaria and inflammatory bowel diseases.
At CymitQuimica, we offer high-purity sulphonamides and their derivatives for research in microbiology and pharmaceutical development.
Found 2592 products of "Sulfonamides and Derivatives"
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Mesotrione
CAS:<p>Mesotrione is a selective triketone herbicide</p>Formula:C14H13NO7SPurity:99.39%Color and Shape:Light Yellow Crystalline PowderMolecular weight:339.32Quinine hydrochloride dihydrate
CAS:<p>Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.</p>Formula:C20H24N2O2·HCl·2H2OPurity:99.91%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:396.912-(4-Isobutylphenyl)propanal
CAS:<p>Stability Hygroscopic<br>Applications 2-(4-Isobutylphenyl)propanal is an impurity of the drug Ibuprofen (I140000), a selective cyclooxygenase inhibitor that also inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); (4) Chem. and Eng. News p9, July 4 (2016)<br></p>Formula:C13H18OColor and Shape:NeatMolecular weight:190.28Gliclazide
CAS:<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972), Holmes, B., et al.: Drugs, 27, 301 (1984),<br></p>Formula:C15H21N3O3SColor and Shape:NeatMolecular weight:323.414-Nitro-2-phenoxyaniline
CAS:<p>Impurity Nimesulide EP Impurity D<br>Stability Light Sensitive<br>Applications 4-Nitro-2-phenoxyaniline has been shown to have good AT1 Angiotension Receptor Antagonist activity when combined with Schiff bases.<br>References Shreenivas, M.T., et. al.: J. Pharm. Sci. Technol., 1, 88 (2009)<br></p>Formula:C12H10N2O3Color and Shape:YellowMolecular weight:230.22Glyburide-d3 (methoxy-d3)
CAS:Controlled Product<p>Applications Glyburide-d3 (methoxy-d3) (CAS# 1219803-02-7) is a useful isotopically labeled research compound.<br></p>Formula:C23D3H25ClN3O5SColor and Shape:NeatMolecular weight:497.0224-Acetaminophen Sulfate Potassium Salt
CAS:Controlled ProductFormula:C8H8NO5S·KColor and Shape:BeigeMolecular weight:269.32Iso Furosemide
CAS:<p>Impurity Furosemide EP Impurity A<br>Applications Iso Furosemide (Furosemide EP Impurity A) is a Furosemide (F865000) derivative which enhanced urinary excretion of active kallikrein.<br>References Kirk, K., et al.: J. Biol. Chem., 267, 23475 (1992), Kirk, K., et al.: Biochem. J., 311, 761 (1995), Egee, S., et al.: J. Physiol., 542, 795 ( 2002),<br></p>Formula:C12H11ClN2O5SColor and Shape:Light BrownMolecular weight:330.74Dapsone
CAS:Controlled Product<p>Applications An antibacterial used in the treatment of dermatitis herpetiformis.<br>References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Formula:C12H12N2O2SColor and Shape:NeatMolecular weight:248.30Sulfamethoxazole N4-glucoside (α/β mixture)
CAS:<p>Applications Sulfamethoxazole N4-glucoside is a metabolite of Sulfamethoxazole (S699086) which is an anti bacterial drug. Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 467 (1973), Wormser, G.P., et al.: Drugs, 24, 459 (1982), Wharton, M., et al.: Ann. Intern. Med., 105, 37 (1986),<br></p>Formula:C16H21N3O8SColor and Shape:White To Light Orange ColourMolecular weight:415.42Sulfasalazine 3-Isomer
CAS:Controlled Product<p>Impurity Sulfasalazine EP Impurity F<br>Stability Hygroscopic<br>Applications A positional isomeric impurity of Sulfasalazine (S699084). Sulfasalazine EP Impurity F<br>References Zalipsky, J.J. et al.: J. Pharmac. Sci., 67, 387 (1978);<br></p>Formula:C18H14N4O5SColor and Shape:NeatMolecular weight:398.39Aceclofenac Methyl Ester
CAS:Controlled Product<p>Impurity Aceclofenac EP Impurity D<br>Applications Aceclofenac Methyl Ester (Aceclofenac EP Impurity D) is a 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative as anti-inflammmatory and analgesic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C17H15Cl2NO4Color and Shape:Off-WhiteMolecular weight:368.21Sulfamethizole
CAS:<p>Applications Sulfamethizole is a sulfonamide based antibiotic that exhibit bactericidal activities towards gram-negative bacteria. Sulfamehizole was shown to be effective in treating gram-negative Bacillus AmpC enzyme in elderly patients with lower respiratory tract infection and as well as against microbs responsible for tuberculosis.<br>References Mondelli, M., et al.: J. Molec. Struct., 1036, 180 (2013); Leelakrishnana, S., et al.: Adv. App. Sci. Res., 3, 3502 (2012); Ghoreishi, S.M., et al.: Anal. Lett., 46, 323 (2012);<br></p>Formula:C9H10N4O2S2Color and Shape:WhiteMolecular weight:270.3313N-Nitroso Hydrochlorothiazide
CAS:Formula:C7H7ClN4O5S2Color and Shape:Off-WhiteMolecular weight:326.7372-(p-sec-Butylphenyl)propionic Acid
CAS:Controlled Product<p>Impurity Ibuprofen EP Impurity O<br>Applications 2-(p-sec-Butylphenyl)propionic Acid (Ibuprofen EP Impurity O) is an impurity of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>Formula:C13H18O2Color and Shape:NeatMolecular weight:206.28Trimethoprim-d9 (Major)
CAS:Controlled Product<p>Applications Deuterated Trimethoprim, an antibacterial.contains 90% D9, 10% D6 and no D0<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Formula:C14D9H9N4O3Color and Shape:Off-WhiteMolecular weight:299.37Glibornuride
CAS:Controlled Product<p>Applications Glibornuride has been shown to antagonize the relaxant response to the K+ channel opener cromakalim and produce airway smooth muscle relaxation. Glibornuride is associated with lactic acidosis and hypoglycemia in patients with type 2 diabetes melitus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mielsen-Kudsk, J.E., Thirstrup, S.: Pulm. Pharmacol., 6, 185 (1993); Bodmer, M., et. al.: Diabetes Care, 31, 2086 (2008)<br></p>Formula:C18H26N2O4SColor and Shape:White To Off-WhiteMolecular weight:366.485-Chloro Hydrochlorothiazide
CAS:Controlled Product<p>Impurity Hydrochlorothiazide 5-Chloro Impurity<br>Applications Hydrochlorothiazide derivative. Diuretic agent.<br>References Mayer, S.E., et al.: J. Pharmacol. Exp. Therap., 134, 18 (1961),<br></p>Formula:C7H7Cl2N3O4S2Color and Shape:Off White SolidMolecular weight:332.182,3-Dimethyl-N-phenylbenzenamine
CAS:Controlled Product<p>Applications 2,3-Dimethyl-N-phenylbenzenamine is a lipophilic compound that is a commonly used non-steroidal anti-inflammatory drug (NSAID).<br>References El Haj, B. M., et al.: Forensic Sci. Int., 105, 141 (1999); Velkov, T., et al.: Chem. Biol., 14, 453 (2007)<br></p>Formula:C14H15NColor and Shape:White To BeigeMolecular weight:197.28Saccharin N-(2-Acetic Acid Ethyl Ester)(Piroxicam Impurity E)
CAS:Controlled Product<p>Impurity Piroxicam EP Impurity E<br>Applications Piroxicam impurity E.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Formula:C11H11NO5SColor and Shape:White To Off-WhiteMolecular weight:269.27(S)-(+)-Ibuprofen-d3
CAS:Controlled Product<p>Applications A labelled nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formula:C13H15D3O2Color and Shape:NeatMolecular weight:209.3Nicosulfuron
CAS:Controlled Product<p>Stability Hygroscopic, Unstable in DMSO<br>Applications Post-emergence sulfonylurea herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gubbiga, N.G., et al.: Weed Technol., 9, 574 (1995), Ukrainczyk, L., et al.: J. Agric. Food Chem., 43, 855 (1995)<br></p>Formula:C15H18N6O6SColor and Shape:White To Off-WhiteMolecular weight:410.40meta-Glimepiride Impurity.
CAS:Controlled ProductFormula:C24H34N4O5SColor and Shape:WhiteMolecular weight:490.62Acetaminophen Glutathione-d3 Disodium Salt (~90%)
CAS:Controlled ProductFormula:C18H19D3N4Na2O8SPurity:~90%Color and Shape:Off-White To Dark BrownMolecular weight:503.45Trimethoprim Lactate Salt
CAS:Controlled Product<p>Applications Trimethoprim lactate salt is an antibacterial agent.<br>References Lees, G. et al.: Brit. J. Pharmacol., 73, 535 (1981);<br></p>Formula:C14H18N4O3·C3H6O3Color and Shape:NeatMolecular weight:290.32 + (90.08)2,4'-Diaminophenyl Sulfone
CAS:Controlled ProductFormula:C12H12N2O2SColor and Shape:NeatMolecular weight:248.30088Niflumic Acid-d5 (Major)
CAS:Controlled Product<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Formula:C13H4D5F3N2O2Color and Shape:NeatMolecular weight:287.254-Amino-4'-hydroxydiphenylsulfone
CAS:<p>Stability Hygroscopic<br>Applications 4-Amino-4'-hydroxydiphenylsulfone is a diaryl sulfone with antileprotic activity. 4-Amino-4'-hydroxydiphenylsulfone is an antibacterial agent.<br>References Colwell, W.T. et al.: J. Med. Chem., 17, 142 (1974); Agrawal, V.K. et al.: Acta Microb iol. Immunol. Hung., 50, 385 (2003);<br></p>Formula:C12H11NO3SColor and Shape:Light BrownMolecular weight:249.291-Cyclohexyl-3-(p-sulfamoylphenethyl)urea
CAS:Controlled Product<p>Impurity Glipizide EP Impurity H<br>Applications 1-Cyclohexyl-3-(p-sulfamoylphenethyl)urea (Glipizide EP Impurity H) is an impurity of Glipizide (G410225).<br>References Jurca, B. et al.: J. Therm. Anal. Calor., 62, 859 (2000);<br></p>Formula:C15H23N3O3SColor and Shape:WhiteMolecular weight:325.43N-(1-Phenylethyl) Ibuprofen Amide(Mixture of 4 Diastereomers)
CAS:Controlled Product<p>Applications Ibuprofen (I140000) impurity, an anti-inflammatory compound.<br>References Rubin, A., et al.: J. Pharm. Sci., 74, 82 (1985), Tracy, T., et al.: Drug Metab. Dispos., 20, 322 (1992),<br></p>Formula:C21H27NOColor and Shape:WhiteMolecular weight:309.45Penoxsulam
CAS:<p>Applications Penoxsulam is an acetolactate synthase inhibitor herbicide developed for controlling grasses, sedges, and broadleaf weeds in rice culture.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jabusch, T., and Tjeerdema, R.: J. Agric. Food Chem. 53, 18, 7179-183 (2005); Bamcjero, M., et al.: Sci. Total Environ. 807, 1, 160793 (2021)<br></p>Formula:C16H14F5N5O5SColor and Shape:White To Light BrownMolecular weight:483.37[4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulfonyl]carb
CAS:Controlled Product<p>Impurity Glimepiride Ethyl Ester Impurity<br>Applications Intermediate for the preparation of Glimepiride (G410150) and some substituted sulfonyl urea antidiabetics. Glimepiride Ethyl Ester Impurity<br></p>Formula:C19H25N3O6SColor and Shape:NeatMolecular weight:423.48N-Acetyl Sulfadiazine-13C6
CAS:Controlled Product<p>Applications A major metabolite of Sulfadiazine.<br>References Woolley, J., et al.: Drug Metab. Dispos., 7, 94 (1979), Nielsen, P., et al.: Biochem. Pharmacol., 35, 2509 (1986), Anari, M., et al.: Anal. Chem., 76, 823 (2004), Edlund, P., et al.: J. Pharm. Biomed. Anal., 34, 1079 (2004),<br></p>Formula:C613C6H12N4O3SColor and Shape:NeatMolecular weight:298.27Acetazolamide Disulphide Impurity
CAS:<p>Impurity Acetazolamide Disulphide Impurity<br>Applications bis(2-Acetamido-1,3,4-thiadiazol-5-yl) Disulfide is an impurity of Acetazolamide (A161500), a carbonic anhydrase inhibitor. Diuretic. (Acetazolamide Disulphide Impurity)<br>References Srinivasu, P., et. al.: J. Pharmaceut. Biomed. Anal., 52, 142 (2010); Vitale, R., et al.: J. Med. Chem., 52, 5990 (2009); Bell, H., et al.: Am. J. Physiol., 297, R370 (2009); Maresca, A., et al.: Bioorg. Med. Chem. Lett., 19, 4929 (2009); Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009)<br></p>Formula:C8H8N6O2S4Color and Shape:NeatMolecular weight:348.45Bumetanide Butyl Ester
CAS:Controlled Product<p>Applications Bumetanide Butyl Ester is an intermediate in the preparation of Bumetanide<br>References Petzinger, E., et al.: Am. J. Physiol., 265, G942 (1993);<br></p>Formula:C21H28N2O5SColor and Shape:NeatMolecular weight:420.52Acetaminophen Acetate (Acetaminophen Impurity)
CAS:<p>Impurity Paracetamol EP Impurity H/ Acetaminophen impurity H<br>Applications Acetaminophen Acetate is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C10H11NO3Color and Shape:White To Off-WhiteMolecular weight:193.20Sulfadoxine
CAS:Controlled Product<p>Applications Used as an antibacterial.<br>References Kapoor, V.K., et al.: Anal. Profiles Drug Subs., 17, 571 (1988)<br></p>Formula:C12H14N4O4SColor and Shape:WhiteMolecular weight:310.33Dapsone Hydroxylamine
CAS:<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of Dapsone.<br>References Preuss, C.V., et al.: Biochem. Pharmacol., 51, 1661 (1996), F., et al.: J. Pharmacol. Exp. Ther., 323, 771 (2007), Roychowdhury, S., et al.: Drug Metab. Disposition, 35, 676 (2007), Obach, R., et al.: Environ. Mol. Mutagen., 49, 631 (2008), Veggi, L., et al.: Life Sci., 83, 155 (2008), Khan,<br></p>Formula:C12H12N2O3SColor and Shape:Off-WhiteMolecular weight:264.30Azoxydapsone
CAS:Controlled Product<p>Applications Azoxydapsone is a primary urinary N-oxidation metabolite of Dapsone (D193250); an antibacterial used in the treatment of dermatitis herpetiformis.<br>References Israili, Z.H., et al.: J. Pharmacol. Exp. Ther., 187, 138 (1973); Cucinell, S.A., et al.: Am. J. Trop. Med. Hyg., 21, 322 (1972); Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950); Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009); Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009); Varma, M., et al.: J. Med. Chem., 52, 4844 (2009)<br></p>Formula:C24H20N4O5S2Color and Shape:NeatMolecular weight:508.57Sulfacetamide
CAS:Controlled Product<p>Applications Sulfacetamide is an antibiotic used for the treatment of skin infections and urinary tract infections. Sulfacetamide is also used to treat acne and seborrheic dermatitis. Sulfacetamide was investigated for potential anti-inflammatory properties<br>References Wittwer, M.B., et al.: J. Med. Chem., 56, 781 (2013); Wang. X., et al.: Afr. J. Micriobiol., 6, 4533 (2012); Yu, B., et al.: Euro. J. Med. Chem., 46, 5833 (2011);<br></p>Formula:C8H10N2O3SColor and Shape:Off-WhiteMolecular weight:214.24
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