Sulfonamides and Derivatives
Sulphonamides are compounds that contain a sulphonamide functional group (-SO₂NH₂), where a sulphur atom is bonded to an amino group. They were among the first synthetic antibiotics used in medicine, inhibiting folic acid synthesis in bacteria, which gives them antimicrobial properties. They are mainly used to treat bacterial infections, although their use has declined due to antimicrobial resistance. In addition to their use as antibiotics, sulphonamides also have applications in the treatment of diseases such as malaria and inflammatory bowel diseases.
At CymitQuimica, we offer high-purity sulphonamides and their derivatives for research in microbiology and pharmaceutical development.
Found 2592 products of "Sulfonamides and Derivatives"
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rac Etodolac-d3
CAS:Controlled Product<p>Applications Labelled Etodolac (E933100). Anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987), Balfour, J.A, et al.: Drugs, 42, 274 (1991),<br></p>Formula:C17D3H18NO3Color and Shape:NeatMolecular weight:290.37Sulfamethoxazole-d4
CAS:Controlled Product<p>Applications The isotopically labelled antibacterial drug Sulfamethoxazole (S699086). Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 467 (1973), Wormser, G.P., et al.: Drugs, 24, 459 (1982), Wharton, M., et al.: Ann. Intern. Med., 105, 37 (1986),<br></p>Formula:C102H4H7N3O3SColor and Shape:Light YellowMolecular weight:257.30Desmethyl Piroxicam (Piroxicam Impurity B)
CAS:Controlled ProductFormula:C14H11N3O4SColor and Shape:NeatMolecular weight:317.32Sulfamethoxazole-13C6
CAS:<p>Applications Sulfamethoxazole-13C6 is the isotope labelled analog of Sulfamethoxazole (S699086). An antibacterial drug. Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 467 (1973), Wormser, G.P., et al.: Drugs, 24, 459 (1982), Wharton, M., et al.: Ann. Intern. Med., 105, 37 (1986),<br></p>Formula:C6C4H11N3O3SColor and Shape:White To Off-WhiteMolecular weight:259.23Cyclohexylamine
CAS:Controlled Product<p>Impurity Glipizide EP Impurity B<br>Applications Cyclohexylamine (Glipizide EP Impurity B) is a building block for pharmaceuticals that has been used for the preparation of paromomycin analogs to be used as aminogycoside antibiotics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosenblum, I., Rosenblum, G.: Toxicol. Appl. Pharm., 12, 260 (1968); Hanessian, S., et. al.: J. Med. Chem., 50, 2352 (2007)<br></p>Formula:C6H13NColor and Shape:NeatMolecular weight:99.17Trichlormethiazide
CAS:Controlled Product<p>Applications Trichlormethiazide, is a diuretic, having similar properties as Hydrochlorothiazide (H714560). It is used for the treatment of oedema (including that which is associated with heart failure, hepatic cirrhosis and corticosteroid therapy) and hypertension.<br>References Imamura, T., et al.: International Heart J., 54(1), 48 (2013); Takahashi, Y., et al.: Cardiovas. Diabetology, 10(1), 45 (2011);<br></p>Formula:C8H8Cl3N3O4S2Color and Shape:NeatMolecular weight:380.66N-(4-Aminobenzenesulfonyl) Sulfamethoxazole
CAS:Controlled Product<p>Impurity Salmeterol EP Impurity B<br>Applications A novel antibacterial analog of the antibacterial drug Sulfamethoxazole (S699086).<br></p>Formula:C16H16N4O5S2Color and Shape:NeatMolecular weight:408.45Acetazolamide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Carbonic anhydrase inhibitor. Diuretic.<br>References Vitale, R., et al.: J. Med. Chem., 52, 5990 (2009), Bell, H., et al.: Am. J. Physiol., 297, R370 (2009), Maresca, A., et al.: Bioorg. Med. Chem. Lett., 19, 4929 (2009), Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009),<br></p>Formula:C4H6N4O3S2Color and Shape:Off-WhiteMolecular weight:222.25Ibuprofen 1,4-Sorbitan Ester
Controlled Product<p>Applications Ibuprofen 1,4-Sorbitan Ester is an impurity of the drug Ibuprofen (I140000), a selective inhibitor of cyclooxygenase, PGH synthase-1 and PGH synthase-2.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); (4) Chem. and Eng. News p9, July 4 (2016)<br></p>Formula:C19H28O6Color and Shape:NeatMolecular weight:352.422Limaprost
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Formula:C22H36O5Color and Shape:NeatMolecular weight:380.52Glipizide-d11
CAS:Controlled Product<p>Applications Labelled Glipizide (G410225). A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ambrogi, et al.: Arzneimittel-Forsch., 21, 200 (1971), Fuccella, et al.: J. Clin. Pharmacol., 13, 68 (1973), Brogden, R.N., et al.: Drugs, 18, 329 (1979), Lebovitz, H.E., et al.: Pharmacother., 5, 63 (1985)<br></p>Formula:C21D11H16N5O4SColor and Shape:WhiteMolecular weight:456.64-Carboxy Tolbutamide
CAS:Controlled ProductFormula:C12H16N2O5SColor and Shape:NeatMolecular weight:300.33Rimsulfuron
CAS:Controlled Product<p>Applications Rimsulfuron is used as a pesticide.<br>References Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007), Wolters, A., et al.: Sci. Total Environ., 405, 269 (2008),<br></p>Formula:C14H17N5O7S2Color and Shape:WhiteMolecular weight:431.44m-Isobutyl Ibuprofen
CAS:<p>Impurity Ibuprofen EP Impurity A<br>Applications m-Isobutyl Ibuprofen (Ibuprofen EP Impurity A) is an Ibuprofen (I140000) impurity used in the study of potent noncompetitive interleukin-8 inhibitors.<br>References Moriconi, A. et al.: J. Med. Chem., 50, 3984 (2007); Allegretti, M. et al.: J. Med. Chem., 48, 4312 (2005);<br></p>Formula:C13H18O2Color and Shape:NeatMolecular weight:206.282-Naphthol
CAS:<p>Applications: Has been used as antiseptic, anthelmintic and counter-irritant in alopecia.<br>Dangerous Goods Info: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Diggle, S., et al.: Chem. Biol., 13, 701 (2006), Tashiro, Y., et al.: J. Bacteriol.,190, 3969 (2008),<br></p>Formula:C10H8OColor and Shape:NeatMolecular weight:144.174’-Hydroxy Nimesulide
CAS:Controlled Product<p>Applications The main metabolite of Nimesulide (N477500).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Facino, R.M., et al.: Drugs, 46 (Suppl1),15 (1993), Westphal, J., et al.: J. Antimicrob. Chemother., 33, 387 (1994), Castell, J., et al.: Cell Biol. Toxicol., 13, 331 (1997), Georges, H., et al.: Life Sci., 65, 151 (1999), Singla, A.K., et al.: J. Pharm. Pharmacol., 52, 467 (2000),<br></p>Formula:C13H12N2O6SColor and Shape:White To Light BrownMolecular weight:324.31Sulfathiazole-d4
CAS:Controlled ProductFormula:C92H4H5N3O2S2Color and Shape:Light YellowMolecular weight:259.344-Acetaminophen-d3 Sulfate Potassium Salt
CAS:Controlled Product<p>Applications 4-Acetaminophen-d3 Sulfate Potassium Salt is a deuterium labeled metabolite of Acetaminophen (A161220) (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961)(2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Formula:C8H5D3KNO5SColor and Shape:NeatMolecular weight:272.33
