Monosaccharides

Synthetic carbohydrate building block

Benzyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-phthalamido-a-D-glucopyranoside is a sugar that is used as a building block for the synthesis of glycosaminoglycans. This sugar can be fluorinated, glycosylated, or methylated and is a synthetically modified oligosaccharide with an average molecular weight of about 880 Da. The monomer unit consists of two glucose residues linked by an α(1→4) glycosidic bond. It has been shown to have antihypertensive properties in vitro and in vivo.

1,2-O-Isopropylidene-3-deoxy-3-fluoro-a-D-glucofuranose is a synthetic sugar that is used in the preparation of glycoproteins. It is an oligosaccharide and a monosaccharide, which means it consists of many saccharides linked together. It has a molecular weight of 568.8 g/mol and belongs to the class of carbohydrates. 1,2-O-Isopropylidene-3-deoxy-3-fluoro-a -D -glucofuranose can be synthesized from 3,4,5,6 tetraacetyl glucose by a click modification reaction with N-(9H-[1,2]dithiolanyl)sulfenamide and then fluorination with N-[(9H-[1,2]dithiolanyl)sulfonyl]triflu

Allyl 2-acetamido-2-deoxy-a-D-glucopyranoside is a synthetic oligosaccharide that has the ability to bind to the O antigen of bacterial cells. It is used in vaccines as an adjuvant and has been shown to increase antibody production and provide protection against Shigella, a bacterial infection. This compound also shows chemoenzymatic activity, which allows for regiospecifically catalytic conversion of glycosides. Allyl 2-acetamido-2-deoxy-a-D-glucopyranoside binds to specific microbial enzymes that contain an acceptor site, with its catalytic function being activated by these enzymes.

2-(3,4-Dihydroxyphenyl)ethyl b-D-glucopyranoside (2,3,4-DHPEB) is a naturally occurring phenolic acid. It has been shown to have antidepressant activity in mice and rats. 2,3,4-DHPEB inhibits the growth of Streptococcus faecalis by inhibiting fatty acid biosynthesis. This compound also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. 2,3,4-DHPEB is a ligand for PPAR receptors and activates their transcriptional activity in cells. It has been shown to have chemopreventive effects against colon cancer cell lines and is able to induce apoptosis in tumor cells.

4-Methoxyphenyl 2-deoxy-4,6-O-(4-methoxybenzylidene)-2-phthalimido-b-D-glucopyranoside is a complex carbohydrate that has been modified with methylation and glycosylation. This product can be used for custom synthesis and is a high purity product. It is soluble in water. The CAS number for this compound is 57810-97-0. The molecular weight of this product is 576. The chemical formula for this compound is C24H28N2O8F3O7, which corresponds to an empirical formula of C24H28N2O8F3O7.

Arabinonic acid potassium salt is a fluorinated monosaccharide that is used as a building block for the synthesis of oligosaccharides and polysaccharides. Arabinonic acid potassium salt is chemically synthesized by the glycosylation of 2-deoxy-D-ribose with arabinonitrile followed by hydrolysis to form arabinonic acid. This chemical can also be modified with methyl groups, nitro groups, or other functional groups. It has CAS number 36232-89-0 and molecular weight of 176.17 g/mol. Arabinonic acid potassium salt is a high purity product with 98% minimum purity and no detectable impurities.

1,2,3,4-Tetra-O-pivaloyl-6-O-(tert-butyldiphenylsilyl)-b-D-galactopyranose is a high purity custom synthesis of a sugar. It is a fluorinated tetra saccharide with an unusual 1,2,3,4 linkage that has been modified with methyl groups at the 2 and 6 positions. The modification of this compound with silylation has made it resistant to enzymatic degradation. This compound has shown anti-inflammatory activities in animal models and can be used as an adjuvant therapy for inflammatory bowel disease.

Methyl 6-amino-6-deoxy-a-D-glucopyranoside is a saccharide with a molecular weight of 362.4 g/mol. This carbohydrate is fluorinated and modified with an amine group on the C1 position, which makes it a complex carbohydrate. It can be custom synthesized to order and has high purity. CAS No. 5155-47-5

Donor for Koenigs-Knorr type galactosylation and other anomeric substitutions

4-Methoxyphenyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-b-D-glucopyranoside is a complex carbohydrate that has been modified with methylation and glycosylation. It has been synthesized using the following reactants: 4-(methoxy)phenol, benzaldehyde, and 2,3,4,6,-tetraacetylpiperidine. This product has a CAS number of 129575–88–8 and is available for custom synthesis in quantities from 1 gram to 50 kilograms. This product is used as a custom synthesis for oligosaccharides or polysaccharides.

Low-calorie sweetener; additive in detergents, cosmetics, and pharmaceuticals

Resource for the synthesis of Clofarabine and other bioactive arabinosides

1,2,3,4-Tetra-O-benzyl-a-D-mannopyranoside is an active drug that belongs to the group of thyromimetics. It is a prodrug that is hydrolyzed in vivo to 1,2,3,4-tetra-O-acetyl-a-D-mannopyranose. This drug has been shown to be effective in treating nervous system diseases such as sclerosis and endogenous disease. The acetylation of the benzyl group on this molecule prevents it from being metabolized by enzymes that are found in the liver. The unmodified form of this drug is rapidly absorbed into the blood and reaches high concentrations quickly.

Methyl a-D-xylopyranoside is an iron chelator that can be used as a mycobacterial drug candidate. It binds to both ferric and ferrous iron, and has been shown to inhibit the uptake of ferric iron by Mycobacterium tuberculosis. It also inhibits the synthesis of siderophores, which are molecules produced by bacteria in order to acquire iron from their environment. Methyl a-D-xylopyranoside does not bind to the alpha-d-glucopyranoside moiety typically found in iron complexes. This is due to its hydroxamate group, which causes it to have an increased affinity for Fe3+. This compound is active against gram negative bacteria such as E. coli and Salmonella enterica serovar Typhimurium, but not against gram positive organisms such as Staphylococcus aureus or Streptococcus pneumoniae.

1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-D-glucopyranose is a small molecule that binds to the D1 protein of the glycolytic enzyme phosphofructokinase and inhibits enzymatic activity. This inhibitor is used in diagnostic procedures to identify mutations in the gene encoding for this protein, which is associated with familial and sporadic aneurysms. The inhibitor is also used to study the pathogenic mechanism of aneurysms. 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy--D--glucopyranose has been shown to inhibit cell nuclei polymerase in vitro and prevents cell division in vivo.

2,3,4,6-Tetra-O-acetyl-b-D-thiogalactopyranose is a synthetic sugar that is prepared by the fluorination of D-galactopyranose and subsequent acetylation. This compound can be used for glycosylation reactions and as a substrate for click chemistry. It is an oligosaccharide with four monosaccharides in its backbone. The CAS number of 2,3,4,6-Tetra-O-acetyl-b-D-thiogalactopyranose is 50615-66-2.