Monosaccharides

<p>Dapagliflozin is an oral antidiabetic drug that acts by inhibiting the SGLT2 enzyme. The SGLT2 enzyme is responsible for reabsorbing glucose from the kidney, so by inhibiting this enzyme, glucose will be excreted in the urine and blood glucose levels will decrease. Dapagliflozin also has a low bioavailability in vivo, which can be improved by administration with food. This drug has been shown to have a longer elimination half-life than canagliflozin and empagliflozin. Dapagliflozin has been shown to have a higher potency than metformin hydrochloride in vitro.</p>

<p>Myricitrin is a natural compound that is found in the bark of the Myrica tree. It has been shown to have antioxidant effects and pro-apoptotic activities. Myricitrin has been shown to induce apoptosis in HL-60 cells through activation of the caspase-3 pathway, which includes cleavage of poly (ADP-ribose) polymerase and activation of caspases. In addition, myricitrin induces apoptosis by binding to DNA and inhibiting transcription. The physiological effects of myricetin are similar to those of myricitrin due to their structural similarity. However, there is no data available on the anti-inflammatory properties or hypoglycemic effect of myricetin.</p>

<p>UDP-6-azido-6-deoxy-D-glucose is a chemical building block that is used for saccharide synthesis. The azide group can be reduced to give the amine which has been used to make a fluorescent tag for 5-(hydroxymethyl)cytosine in DNA. UDP-6-azido-6-deoxy-D-glucose has also been used to synthesise siderophore conjugates which can be used to deliver functional reagents across bacterial cell membranes.</p>

<p>Ethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-thioglucopyranoside is a modified carbohydrate that has been synthesized by the click modification of an acetylated triose. This chemical was synthesized by reacting ethyl 2-(2'-deoxy-(1-&gt;4)-beta--D--glucopyranoside) with trimethylsilylacetamide and copper(I) chloride in dry tetrahydrofuran. This product has high purity and is used as a research tool for glycobiology.</p>

<p>Diethoxy phosphonyl 4,7,8,9-tetra-O-acetyl-N-acetyl-D-neuraminic acid methyl ester is a glycosylation agent that is used in the synthesis of complex carbohydrates. It is a methylated derivative of 4,7,8,9 tetra-O-acetyl neuraminic acid and can be used to modify the polysaccharide structure. This product has been shown to react with saccharides and oligosaccharides in a click reaction to produce fluorinated derivatives. Diethoxy phosphonyl 4,7,8,9 tetra-O-acetyl neuraminic acid methyl ester is also available as a custom synthesis.</p>

<p>Diosmetin-3'-O-b-D-glucuronide is a custom synthesis, complex carbohydrate, Oligosaccharide, Polysaccharide. It has been modified by Methylation and Glycosylation. This compound is a sugar (CAS No. 152503-50-9) that is a carbohydrate with a high purity and fluoroination. The modification of this compound includes Click chemistry.</p>

<p>Methyl 4,6-O-benzylidene-a-D-galactopyranoside is a high purity, custom synthesis, sugar modified product. It has a CAS No. 72904-85-9, and can be synthesized by the click modification of methyl 1,4-O-diacetyl D-mannopyranoside. The fluorination of the glucose moiety in this molecule is accomplished using NCS/BF3 complex in acetonitrile. Glycosylation is achieved using NEM/HBTU and DCC in DMF. The saccharide is then modified with methyl 4,6-O-benzylidene alditol acetate to yield Methyl 4,6-O-benzylidene a D galactopyranoside. This product can also be synthesized by the glycosylation of methyl 2,5 dihydroxyacetophenone with methyl</p>

<p>2,4,7,8-Tetra-O-acetyl-9-azido-9-deoxy-N-acetylneuraminic acid methyl ester is a high purity synthetic compound that has been modified for use in Click chemistry. It is a monosaccharide with an acetyl group on the 2' position and an azido group on the 9' position of the sugar. This compound is used in fluoroination reactions to modify sugars and oligosaccharides. It can also be used in glycosylation reactions to attach monosaccharides and saccharides to proteins or other molecules.</p>

<p>N1-a-L-Arabinopyranosylamino-guanidine HCl is a carbohydrate that belongs to the class of oligosaccharides. It is a synthetic compound, which is custom synthesized for use in research. This product has been shown to be high purity and is methylated, glycosylated, and click modified. The CAS number 109853-78-3 refers to the chemical name of this product. The molecular weight of N1-a-L-Arabinopyranosylamino-guanidine HCl is 597.14 g/mol with an empirical formula C8H23N2O6.</p>

<p>Intermediate for β-glucosides; potential PET surface modification reagent</p>

<p>Propyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a synthetic monosaccharide that has been fluorinated and methylated. It is a custom synthesis and can be modified to suit your needs. This compound has been glycosylated and click modified. The purity of this product is high and it's molecular weight is 798 Da.</p>

<p>D-Glucosamine 6-phosphate is a non-essential amino acid that belongs to the group of nucleotide sugar phosphates. It is a metabolite of the sugar D-glucose and it plays an important role in the energy metabolism of bacteria, plants, and animals. It has been shown to have anti-cancer effects on prostate cancer cells. D-Glucosamine 6-phosphate inhibits methyltransferase activity by binding to the enzyme's active site. This inhibition prevents DNA synthesis, leading to cell death. The structural analysis has been done using NMR spectroscopy on d-arabinose as a model substrate.</p>

<p>A gallotannin found in plants, with various biological activities. Its anti-cancer effect has been demonstrated in several cancer cell lines, mediated by inhibition of DNA replication, proliferation and angiogenesis. Elicits anti-inflammatory, antioxidative and anti-diabetic effects. Recently, it has been identified as an inhibitor of c-Myc in hepatocellular carcinoma and multiple myeloma cells.</p>

<p>D-Threitol is a carbohydrate that has been shown to have anti-microbial activity against a number of microbes, including E. coli, Klebsiella pneumoniae, Bacillus subtilis, and Staphylococcus aureus. It may also be useful in the treatment of microbial infections in the respiratory tract. D-Threitol is an analogue of threitol with an acyl chain at the 4 position instead of the 5 position. The allyl carbonate moiety can be cleaved by acid to form an acid complex, which is more stable than D-threitol. D-Threitol binds to antibody response sites on cells, thereby preventing cells from responding to pathogens or other foreign bodies by initiating appropriate immune responses. This binding also prevents bacteria from attaching themselves to cell walls.</p>

<p>D-Mannose-6-phosphate sodium salt (DMSP) is a phosphorylated sugar that is produced by the enzyme expressed in the yeast, Saccharomyces cerevisiae. DMSP has been shown to be involved in the synthesis of phosphatidylcholine and other lipids. Its solubilization and adsorption properties have been studied using dibutyryl camp, which is a lipid found in milk fat. The amino acid analysis of DMSP revealed that it contains both D-mannose residues and 6-phosphate groups. The 6-phosphate group is found only on one side of the molecule, which may contribute to its asymmetry.</p>

<p>Phenyl 2,3,4-tri-O-benzyl-b-L-thiofucopyranose is a synthetic monosaccharide that is modified with fluorine. It is also known as 3,4,6-tri-O-benzyl-2,3,4,6-tetra-O-(trifluoromethyl) fucopyranose. This compound is a complex carbohydrate that belongs to the group of glycoconjugates and polysaccharides. Phenyl 2,3,4-tri-O-benzyl-b-L-thiofucopyranose has been shown to be useful in glycosylation reactions as well as in click chemistry reactions. This compound can be used for the synthesis of oligosaccharides and polysaccharides with custom modifications. Phenyl 2,3,4 tri O benzyl b L thiof</p>

<p>Petunidin 3-glucoside chloride is a natural compound found in the human serum and in kidney beans. It is structurally similar to chlorogenic acid, a major phenolic acid in coffee. Petunidin 3-glucoside chloride is extracted using hydrochloric acid and then purified by a surface methodology. The main degradation products of this compound are protocatechuic acid, fluorescence detector, procyanidin B4, and malonic acid. This compound can be used as an antioxidant or chemoattractant protein. It has been shown to have high levels of anthocyanins and trifluoroacetic acid (TFA) when exposed to sunlight.</p>

<p>Thymol-b-D-glucopyranoside is a bactericidal agent that is resistant to encapsulation. It has been shown to be effective against animals and typhimurium in an incubated population and endogenous deaminase inhibitor strategy. The porcine activated food chemistry and abattoir experiments show that thymol-b-D-glucopyranoside has the potential to reduce populations of bacteria in the gastrointestinal tract by inhibiting protein synthesis.</p>

<p>1,3:2,4-Bis(O-benzylidene)-D-sorbitol is a hydrogenated derivative of sorbitol. It is used in fatty acid devices and as a surfactant in hydrogenation reactions. 1,3:2,4-Bis(O-benzylidene)-D-sorbitol is an acidic compound that has a low molecular mass and is soluble in water. It reacts with magnesium oxide to form the corresponding magnesium salt. This derivative is also used in silicone residue removal and as an activated organic base.</p>

<p>2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl-Fmoc serine is a protein that belongs to the group of bifunctional glycosides. It is used in recombinant virus production as a component of the viral coat protein (VP). 2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl-Fmoc serine binds to tyrosine kinase receptors and inhibits their activity. This inhibition prevents cell adhesion and migration and can cause tumor regression in some cancers. 2,3,4,6-Tetra-O-acetyl-b-D--glucopyranosyl--Fmoc serine also has antiviral activity due to its ability to inhibit the replication of viruses containing RNA genomes.</p>