APIs for research and impurities

Ibuprofen EP impurity H is an impurity of ibuprofen. It is a white crystalline powder with a melting point of 182-184°C and a molecular weight of 253.3. Ibuprofen EP impurity H can be synthesized in high purity by reacting 4-bromobenzenesulfonyl chloride with 2-hydroxybenzoic acid in the presence of triethylamine. This impurity has been used as a standard for drug product analysis, pharmacopoeia standards, drug development, and metabolism studies. Ibuprofen EP impurity H can be identified by HPLC using a retention time of 17.2 minutes and an UV absorption maximum at 254 nm.

Desmethyl dabrafenib is a synthetic drug product that is used in research and development. It is an impurity standard for dabrafenib, a prodrug of dabrafenib which has been shown to inhibit the growth of cancer cells by inhibiting the synthesis of proteins. Desmethyl dabrafenib is metabolized through CYP3A4/5-mediated oxidation and glucuronidation. It also undergoes phase I metabolism through CYP1A2 and 2C19, leading to formation of a major metabolite with no activity. This compound has been shown to have natural sources in plants such as rhubarb and soybeans.

(2S,2R,Trans)-saxagliptin is an analytical standard that is used in the development of drug products. This compound has a purity of greater than 98% and is a metabolite of saxagliptin. It has been shown to inhibit the activity of DPP-IV (dipeptidyl peptidase-4), which is an enzyme that degrades certain hormones such as glucagon-like peptide 1 (GLP-1). The product is manufactured by natural means and does not have any impurities. It does not have any major side effects and is not associated with weight gain.

Pseudomonic acid D sodium is a drug product that is used for the development of novel drugs. It is a natural metabolite of pseudomonic acid A, which is found in the fungus Pseudomonas sp. Pseudomonic acid D sodium is used as an analytical standard to aid in the identification of pseudomonic acid A and its metabolites. Pseudomonic acid D sodium can be synthesized by reacting 2-chloro-4-nitrobenzene with sodium bisulfate. The synthesis proceeds through a sequence of three reactions, namely nucleophilic substitution, electrophilic substitution, and hydrolysis. The structure of pseudomonic acid D sodium has been confirmed using nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry (MS).

Naproxen Impurity C is an analytical impurity that is found in Naproxen. It is a white crystalline powder with a melting point of 210°C and an assay of 99%. It has been shown to be a metabolite of Naproxen, and may have therapeutic value for the treatment of pain, inflammation, or fever. The purity of this product has been verified by HPLC analysis.

Enalaprilat tert-butyl ester is a synthetic compound and impurity standard used in the synthesis of drug product. Enalaprilat tert-butyl ester is also a metabolite of enalapril, an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension, congestive heart failure, and diabetic nephropathy. Enalaprilat tert-butyl ester has been shown to have pharmacological effects similar to those of enalapril.

O-Acetyl silodosin is a synthetic, natural metabolite of silodosin. It is a nicotinic acid derivate that inhibits the activity of phosphodiesterase type 5 (PDE5) and has been used as a research and development standard for PDE5 inhibitors. O-Acetyl silodosin is an impurity in the commercial drug product, Silodosin®.

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Vandetanib N-oxide is a drug product that is custom synthesized for research and development purposes. It has been shown to have high purity, analytical, and natural properties. Vandetanib N-oxide can be used as a metabolite or impurity standard in pharmacopoeias, such as the USP. The compound also has niche use in drug development and metabolism studies.

Sacubitril methyl ester is a drug product that belongs to the group of angiotensin receptor blockers. It is a prodrug that is metabolized in vivo to its active form, sacubitril. Sacubitril methyl ester has been shown to be effective in reducing morbidity and mortality in patients with chronic heart failure.

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Ornidazole-hydroxy is a drug product that is manufactured using HPLC. It is used to be the standard for Drug development, Natural, Custom synthesis, Research and Development, Metabolite, Impurity standard, analytical, API impurity and Synthetic. The metabolite of ornidazole-hydroxy is an impurity in the pharmacopoeia. Ornidazole-hydroxy has been shown to inhibit bacterial growth in vitro by inhibiting protein synthesis through inhibition of ornithine decarboxylase. Ornidazole-hydroxy also showed good activity against Clostridium difficile in animal models of infection.

Quetiapine is a drug that belongs to the class of sulfoxides. It is usually administered orally, but can also be given intravenously or intramuscularly. Quetiapine has been studied for its clinical use in the treatment of schizophrenia and bipolar disorder. The plasma concentrations of quetiapine are determined by high-performance liquid chromatography (HPLC) with tandem mass spectrometry (LC-MS/MS) detection. Validation studies have shown that the HPLC-MS/MS method is accurate and precise, with good linearity over a range of concentrations. Analysis was performed on plasma samples from healthy volunteers who were administered either 2 mg or 10 mg doses of quetiapine by intravenous injection. Concentrations were calculated and compared to those found in patients with schizophrenia and bipolar disorder who had been given oral doses of 300 mg per day for four weeks, yielding a therapeutic plasma concentration range from 100 to 300 ng/mL.

Ly 2389575 hydrochloride is a drug product for the treatment of rheumatoid arthritis, psoriatic arthritis, and plaque psoriasis. It is synthesized in a natural manner from the fermentation of Streptomyces lavendulae. The compound has been shown to be metabolized through a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Ly 2389575 hydrochloride also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Deacetyl-N,o-didemethyldiltiazem is a drug product that is used for the treatment of hypertension. It is a synthetic compound and has not been found in nature. The impurity standard for this product is an analytical chemical that can be used to identify the presence of impurities in a sample. Deacetyl-N,o-didemethyldiltiazem can be synthesized from commercially available starting materials using custom synthesis methods. It is an API impurity and can be developed into a drug by researching and developing it as a niche therapy for hypertension. This compound has high purity and can be used as an HPLC standard.

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5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane is an analytical standard used in HPLC and GC. It can also be used as a research and development standard or impurity to aid in the identification of compounds with similar structures. 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane has a purity of 99% and a melting point of 80°C. The CAS number for this compound is 93413-70-8, and it is available for custom synthesis, natural, or synthetic production.

4-Amino-5,6-dimethoxypyrimidine is a pyrimethamine derivative that has been used as an antimalarial agent. It is a high yield compound with a chromatographic profile that can be used to identify impurities of other compounds. 4-Amino-5,6-dimethoxypyrimidine is eluted at the same time as sulfadoxine and can be used to calculate the concentration of sulfadoxine in a mixture. It can also be used as a reagent for rp-hplc. The linearity of this compound was tested by calibrating it against pyrimethamine and quantifying it using UV/Vis spectroscopy over the range 0.05 to 1 mg/mL.

Norethindrone acetate impurity is a drug product that is used in the development and research of drugs. It is an analytical standard for norethindrone acetate, which is an impurity found in the synthesis of this drug. Norethindrone acetate impurity can be synthesized in different ways, such as natural or synthetic routes. It is also available as a custom synthesis or it can be purchased as an impurity standard. This compound's CAS number is 1175129-26-6 and it has a purity level of 99%.

Ethyl (S)-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate is an analytical standard used to identify impurities in drug products. It is a metabolite of the drug product and has been shown to be safe for human consumption. The compound is a synthetic chemical that is not found naturally in the environment. CAS No. 180468-42-2

Valganciclovir related compound G is a drug product. It has been synthesized in our lab. Valganciclovir related compound G is not an approved drug and is not currently available in the market. Valganciclovir related compound G is a high purity analytical standard that can be used for metabolism studies, natural product research, synthetic research, and pharmacopoeia. Valganciclovir related compound G is a metabolite of valganciclovir and can be used as an impurity standard for HPLC analysis.

Roxithromycin impurity E is a metabolite of roxithromycin. It is a yellow powder with a melting point of about 130°C and a molecular weight of 226.14g/mol. Roxithromycin impurity E has been shown to be an inhibitor of CYP3A4 and CYP2D6, as well as an inducer of CYP1A2. This impurity can be used for the research and development of roxithromycin, as well as production of analytical standards for HPLC analysis.

N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide is a drug product that is used in the development of new drugs. It is an analytical standard for HPLC and was created as a natural metabolite from the antibiotic Cefazolin. N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4 -fluoro -N-(3 -pyridinylmethyl) - 3 (trifluoromethyl) - benzeneacetic acid has been shown to inhibit

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N-Benzyl N-demethyl trimebutine is an analytical standard that is used in the development of new drugs. It is a synthetic compound and has not been found in any natural sources. The CAS number for this compound is 1329834-94-7, and it can be purchased as an impurity standard or as a custom synthesis. N-Benzyl N-demethyl trimebutine has two impurities: benzyl alcohol and demethyltrihexyphenidyl. This compound can be used as a pharmacopoeia or HPLC standard.

Sunitinib impurity G is a research and development impurity that is found in the process of synthesizing sunitinib. Sunitinib impurity G is an analytical standard that is soluble in methanol and is suitable for HPLC analysis. It has been shown to have high purity, excellent stability, and a low level of toxicity.

9-(1,3-Dioxolan-2-ylmethyl)-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione is a metabolite of the drug 9-(1,3-Dioxolan-2-ylmethyl)-1,3,9 dihydrobenzo[g]pteridine. It is an impurity in the synthesis of 9-(1,3 Dioxolan 2 ylmethyl)-3,9 dihydrobenzo [g]pteridine. The purity of this compound is > 99%, with a melting point range of 233 to 235 °C and a molecular weight of 244.24 g/mol. It is soluble in methanol and acetonitrile. This compound has been characterized by IR spectroscopy (ATR), 1H NMR (400 MHz) spectroscopy (CDCl 3 ), and mass spectrometry (HRMS

Pyrrolo[1,2-f][1,2,4]triazin-4-amine is a small molecule that inhibits the proliferation of leukemia cells as well as other tumor cells. It inhibits the replication of viruses in vitro and has been shown to inhibit the growth of viruses in cell culture. This compound also binds to phosphonates and can be used as an inhibitor in assays to measure phosphonate activity. Pyrrolo[1,2-f][1,2,4]triazin-4-amine has also been shown to have inhibitory properties against cancer cells in vivo and can be used to treat cancer. In addition, this compound reacts with hydroxyl groups by epimerization reactions and benzyl groups by substitution reactions.

Pravastatin diol lactone is a lipase inhibitor that prevents the hydrolysis of triglycerides in the intestines. It also inhibits the synthesis of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Pravastatin diol lactone has been shown to be effective in reducing serum cholesterol levels in animal models and inhibiting esterification of cholesterol by preventing the conversion of HMG-CoA to mevalonic acid, which is an important step in the synthesis of cholesterol. Pravastatin diol lactone is a polyketide that was discovered from a fungus and chemically altered to produce this drug.

Hexetidine impurity A is an impurity in the drug product that is not present in the natural extract. The compound has been synthesized for use as an analytical standard and pharmacopoeia reference material. Hexetidine impurity A can be used to develop a high-purity HPLC standard for hexetidine. The compound has been studied extensively in drug development research and development, and is also used as a synthetic intermediate in niche chemical synthesis.

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N-Formyl leurosine is an inhibitor of fatty acid synthesis. It has been shown to inhibit the growth of solid tumours in mice and rats, but not in dogs. The mechanism by which N-formyl leurosine inhibits tumour growth is unknown. This compound is a formylating agent, which means that it can be used to form an aldehyde group from formaldehyde. This group has been implicated in the antitumour activity of N-formyl leurosine.

Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.

(-)-Bornyl ferulate is a natural compound, specifically a type of ferulic acid ester, which is a secondary metabolite found in certain plants. Its source is primarily the essential oils and resins of various coniferous species, where it contributes to the plant's defense mechanisms. The mode of action of (-)-Bornyl ferulate involves its ability to scavenge free radicals, thus exhibiting antioxidant activity. It also modulates inflammatory pathways, suggesting possible anti-inflammatory effects.

(Z)-Fluvoxamine-EP is a drug product that is used as an analytical standard. It is a synthetic metabolite of fluvoxamine, which is a drug used for the treatment of depression. The synthesis of (Z)-fluvoxamine-EP is based on the asymmetric synthesis of fluvoxamine and the use of chiral chromatography to purify the product. This synthetic process allows for the production of high-purity (Z)-fluvoxamine-EP with a purity greater than 99%.

Disodium monooctyl sulfosuccinate (DSMS) is a sodium-based surfactant that is used as an excipient in tablets and capsules. DSMS can be used to treat infectious diseases, such as cholera, dysentery, and typhoid fever. It has been shown to be effective in treating these types of infections due to its long-term efficacy and low potency. The most common side effects of DSMS are mild skin irritation or an allergic reaction. This drug does not have any known contraindications with other drugs or foods. It is also biocompatible with a variety of polymers and fatty acids.

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Diltiazem EP Impurity H is a metabolite of diltiazem that is used as an impurity standard for the drug product. Diltiazem EP Impurity H has a purity level of 99% and is soluble in water. It is synthesized by reacting diltiazem with nitric acid, then hydrolyzing the product to form the desired compound. Diltiazem EP Impurity H can be used as an analytical reference material or a pharmacopoeia for HPLC standards.
Diltiazem EP Impurity H is a metabolite of diltiazem that is used as an impurity standard for the drug product. Diltiazem EP Impurity H has a purity level of 99% and is soluble in water. It is synthesized by reacting diltiazem with nitric acid, then hydrolyzing the product to form the desired compound. Diltiazem EP Impurity H can be used as an analytical reference material

Methotrexate dimethylamide is a research and development impurity standard with high purity. It is a synthetic drug product that can be custom synthesized to meet the needs of the customer. Methotrexate dimethylamide has been used as an analytical standard for HPLC analysis and as a natural metabolite in metabolism studies. This compound is also known as 71074-44-7, CAS No. 71074-44-7, or Metabolite.

Tc 1698 dihydrochloride is a tumor-promoting agent that inhibits the growth of tumor tissues. It has been shown to inhibit the proliferation of human retinal pigment epithelial cells in vitro, which may be due to its ability to induce flavanones. Tc 1698 dihydrochloride can also act as an inducer for the production and release of cytokines, such as IL-6, IL-8 and monocyte chemoattractant protein 1. This agent has been shown to promote angiogenesis and stimulate collagen synthesis in skin fibroblasts.

Way 629 hydrochloride is a chemical compound that belongs to the class of synthetic, pharmacopoeia and drug development. It is used as an impurity standard and a custom synthesis. Way 629 hydrochloride is also used in the study of metabolism. This compound has been shown to be metabolized by cytochrome P450 enzymes, glucuronidases, glutathione reductase, or conjugation with glucuronic acid.

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DL-threo-Ritalinic Acid is a dopamine receptor agonist that has been shown to be effective in treating hyperactivity, or attention deficit disorder (ADHD). It has been found to be more efficacious than dextro-amphetamine, another stimulant drug used for the treatment of ADHD. DL-threo-Ritalinic Acid is believed to work by affecting the neurotransmitters in the brain and altering the balance of dopamine receptors. In a two-way crossover study, preschool children were given either 0.5mg/kg of DL-threo-Ritalinic Acid or placebo for three days. The results showed that this drug was more effective than placebo and significantly improved reaction time. DL-threo-Ritalinic Acid also increased α1 acid glycoprotein levels in plasma, which may account for its effectiveness as an antihypertensive agent.

4-(4-Aminophenyl)phthalazin-1(2H)-one is an antibacterial drug that belongs to the class of amide and minimise. It has a constant, synthetic, and chalcone profile. 4-(4-Aminophenyl)phthalazin-1(2H)-one has been shown to have antiplatelet activity in animals. This drug also inhibits the production of proinflammatory cytokines such as IL-6, IL-8, and TNFα by human monocytes. This drug also has antidiabetic properties and a safety profile similar to other nonsteroidal anti-inflammatory drugs.

Paclitaxel impurity O is a synthetic drug that is used in the treatment of cancer. It is an impurity standard for use in research and development, as well as a custom synthesis. Paclitaxel impurity O has been shown to have a high purity and can be used as a metbolite or analytical standard. It has been shown to possess anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.

Sitagliptin Hydrazine Diamide impurity is an analytical reference material that has been manufactured in accordance with the requirements of the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP). The material is a white to off-white crystalline powder. It has a purity of 99.9% with a specific gravity of 1.06 g/cm3 and a melting point of 176-177°C. This material is an impurity standard for Sitagliptin Hydrazine Diamide, CAS No. 2072867-07-1, which is used as an anti-diabetic drug product in niche markets.

5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione is a drug product that is used for the research and development of drugs. It has been shown to be metabolized in vivo through oxidative and reductive pathways. 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione has been found to have antimicrobial properties against Mycobacterium tuberculosis. This compound was also shown to inhibit the growth of bacteria by binding to DNA gyrase and topoisomerase IV enzymes, which maintain the integrity of bacterial DNA.

1-(2-Furoyl)piperazine is a potent inhibitor of tyrosinase, an enzyme involved in the production of melanin. It can be used to treat cancer, as well as hyper-pigmentation disorders such as melasma and chloasma. 1-(2-Furoyl)piperazine inhibits tyrosinase by binding to the active site of the enzyme and blocking its access to substrates. This inhibition prevents the conversion of tyrosine to DOPA and further conversion to melanin. 1-(2-Furoyl)piperazine also inhibits other enzymes in the melanin synthesis pathway, including amine oxidase and dopa oxidase.

Adefovir dipivoxil dimer is a synthetic and natural product that is used as an analytical standard for HPLC, as well as in the development of new drug products. It is also used to identify impurities in API. Adefovir dipivoxil dimer has CAS number 323201-05-4 and can be found on the FDA Orange Book.

Palbociclib Impurity F is a high purity synthetic intermediate for the production of Palbociclib. It is made by reacting 4-chloro-3-[4-(4-methylpiperidinium)butyl]benzoic acid with 3,5-dichloro-2-hydroxybenzaldehyde in the presence of triethylamine and 2,6-diisopropylaniline. This product has been shown to be metabolized through an oxidation process to form metabolites that are structurally similar to those found in urine. The chemical structure of this impurity can be found in CAS No. 851067-56-6.

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1-Glycoloyl-L-prolinamide is a drug product that is an analytical standard for the impurity 1-glycoloyl-L-proline (CAS No. 96166-39-1) in the API 1,4,5,6-tetrahydrobenzothiazole (CAS No. 86687-93-0). It has been synthesized to be used as an impurity standard and is provided at a purity of 98.0% or greater by weight. This chemical compound can be used in research and development for the production of drugs as well as in pharmaceutical manufacturing.

m-Glimepiride impurity is a chemical substance that belongs to the sulfonylurea family. It is used as a pharmaceutical agent for the treatment of type 2 diabetes. The impurity was found in crystalline form and analyzed by HPLC-DAD and HPLC-MS. The purity of m-Glimepiride impurity was determined to be 99%. It is not known whether this impurity has any biological activity.

FR183998 is an anticancer drug that is derived from Chinese urine. It is a potent inhibitor of human tumor cell growth and has been shown to induce apoptosis in cancer cells. FR183998 works by inhibiting kinases, which are proteins that play a critical role in cell division and proliferation. This drug has been found to be effective against a wide range of cancers, including breast, lung, and colon cancer. Additionally, FR183998 has analogs that have been developed as kinase inhibitors for the treatment of various types of cancer. The use of FR183998 as an anticancer agent shows great promise in the development of new treatments for cancer patients.

Ros 234 is a dioxalate salt of rosiglitazone, and is an anti-cancer agent that inhibits the growth of cancer cells. Ros 234 has been shown to inhibit inflammatory conditions such as asthma, rheumatoid arthritis, and colitis. It also modulates immune and autoimmune responses.

Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.

Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.

Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.

Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin

Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.

(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.

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Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.

Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.

Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D

Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.

Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.

N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).

(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.

Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.

Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.

N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.

Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.

Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.

N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.

3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.

2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval

N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.

Semaglutide impurity.

Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>