APIs for research and impurities

<p>Please enquire for more information about 2-[4-(Dimethylamino)-1-(2-methylphenyl)butyl]-phenol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Glimepiride EP Impurity G including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Prizidilol is a medicinal inhibitor that has shown promising results as an anticancer agent. It works by inhibiting protein kinases, which are enzymes involved in cell cycle regulation and apoptosis. Prizidilol has been found to be effective against cancer cells in both Chinese hamster and human urine tumor models. This inhibitor has also been shown to have potential as an analog for other inhibitors used in cancer research. Its ability to induce apoptosis in cancer cells makes it a promising candidate for future cancer therapies.</p>

<p>Raltegravir is a drug that inhibits HIV-1 protease. It is an analytical standard for HPLC, and can be used in the development of drugs, including as an impurity standard. Raltegravir has shown promising results in clinical trials, but it is not available commercially. The chemical compound 2-des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-amino-2-oxoacetic acid) raltegravir has CAS No. 1064706-98-4 and is a natural product.</p>

<p>Vitalethine is a protein analog that has been shown to induce apoptosis in cancer cells. It acts as a kinase inhibitor and specifically targets the hepcidin pathway, which is involved in tumor growth and metastasis. Vitalethine has been tested on human cancer cell lines and has shown potent anticancer activity. This protein analog may have potential therapeutic applications for the treatment of various types of cancers. Vitalethine can be detected in urine samples and may serve as a biomarker for cancer diagnosis and monitoring.</p>

<p>4-Hydroxy azithromycin is an impurity of Azithromycin that is a metabolite of the drug. 4-Hydroxy azithromycin is a synthetic product, which has been synthesized for use as an analytical standard for HPLC and LC-MS/MS. It has also been used as a pharmacopoeia standard for testing antibiotic purity and quality. Metabolism studies have shown that 4-hydroxy azithromycin is not absorbed from the gastrointestinal tract, but is found in the urine and feces.</p>

<p>3-[4-(4-Chlorobenzoyl)phenoxy]-2-butanone is an impurity in the drug product, N-{3-[4-(4-chlorobenzoyl)phenoxy]-2-butenyl}acetamide. It can be used as an analytical reference standard for determining the presence of impurities in pharmaceutical products. 3-[4-(4-Chlorobenzoyl)phenoxy]-2-butanone is not a natural component of the API and is typically synthesized with high purity. This compound has been shown to be metabolized by human liver microsomes and rat lung microsomes. The metabolic pathways are unknown but may include oxidation, hydrolysis, or conjugation reactions.</p>

<p>Please enquire for more information about (+)-Papaveroxinoline acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Carboxy nevirapine is a synthetic drug product that is used as an analytical reference standard for the impurity 4-carboxynevirapine. It has been shown to have niche applications in pharmacopoeia and natural product research and development. The metabolite 4-carboxynevirapine can be synthesized from nevirapine which is found in the plant Cinchona officinalis. This metabolite has been extensively studied for its role in the metabolism of nevirapine and its possible therapeutic applications, such as its ability to inhibit HIV replication.</p>

<p>Please enquire for more information about 5-Nitro-2-(pyridin-4-yl)-2,3-dihydro-1H-isoindole-1,3-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5Alpha-Androstan-3alpha,11beta-diol-17-one 3-glucosiduronate is a metabolite of testosterone. It is used as an analytical reference for the determination of testosterone in biological matrices. 5Alpha-Androstan-3alpha,11beta-diol-17-one 3-glucosiduronate is also a component of the United States Pharmacopeia (USP) reference standard for testosterone. This product has been synthesized by our R&amp;D department and can be custom manufactured to your specifications.</p>

<p>Impurity C is a by-product of dorzolamide hydrochloride. It is used as an analytical reference material, in drug development and as an impurity standard for HPLC. It is also used to generate a pharmacopoeia monograph. The CAS number for Impurity C is 70585-27-5.</p>

<p>Fluvoxketone is a drug that belongs to the class of selective non-steroidal anti-inflammatory drugs. It is a mixture of stereoisomers, with a ratio of 1:1, which have different pharmacological properties. Fluvoxketone has an average elution time of 18 minutes and can be detected in the sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) profile at around 10 minutes. This drug was selected as the optimum drug for this study by optimisation of its solubility, selectivity, and stability.</p>

<p>Please enquire for more information about Ozagrel impurity III including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Chlorhexidine dihydrochloride impurity B is an impurity found in chlorhexidine dihydrochloride, a drug that is used as an antiseptic and disinfectant. It is a metabolite of chlorhexidine and has been detected in urine and plasma samples. This impurity has no known pharmacological activity. The purity of this compound is not less than 99%.</p>

<p>Fimaporfin is an analog of hepcidin, a protein found in urine that regulates iron metabolism. It is a kinase inhibitor that induces apoptosis in cancer cells. Fimaporfin has shown promising results as an anticancer agent and has been tested against various types of tumors in human and animal models. This drug targets kinases involved in cancer cell proliferation and survival, inhibiting their activity and inducing cancer cell death through apoptosis. Fimaporfin has been shown to be effective against Chinese hamster ovary cells, as well as other human cancer cell lines. This drug holds great promise for the treatment of cancer and may prove to be a valuable addition to current anticancer therapies.</p>

<p>Ceftazidime t-butyl ester is a prodrug of ceftazidime. It is a crystalline, stable form of the drug that can be dissolved in an organic solvent. Ceftazidime t-butyl ester has an average UV detection wavelength with a linear range of 200-600 nm and can be detected at a wavelength of 220 nm. This drug is used to treat infections caused by bacteria, including those that are resistant to other antibiotics, such as penicillin or ampicillin. Ceftazidime t-butyl ester has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.</p>

<p>(2R)-3-Hydroxyisovaleroyl-d3 carnitine is a drug product that is custom synthesized for research and development. It has a purity of &gt;90%. This product can be used in metabolism studies, natural products, drug development, pharmacopoeia, or as an analytical reference standard. The CAS number for this product is 1058636-00-2. (2R)-3-Hydroxyisovaleroyl-d3 carnitine may also contain impurities of 0.05%. The molecular weight for this compound is 266.37 g/mol and the chemical formula is C5H11NO4.</p>

<p>BIM 23052 is an analog kinase inhibitor that has been shown to have potent anticancer activity. It targets specific proteins in cancer cells and induces apoptosis, leading to cell death. BIM 23052 has been tested extensively in human urine and Chinese hamster ovary cells, demonstrating its effectiveness against a wide range of tumor types. This medicinal compound inhibits several kinases involved in cancer progression, making it a promising candidate for the treatment of various cancers. Its unique mechanism of action makes it a valuable addition to the arsenal of anticancer drugs available today.</p>

<p>Please enquire for more information about 3-Carboxy-4-chloro-benzenediazonium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ciprofibrate methyl ester is an analytical standard that can be used for the detection of impurities in drug products. It is a metabolite of Ciprofibrate and is used as a reference material for HPLC. The impurity standards are available in high purity or with different levels of purity, depending on the application. In addition, it can be custom synthesized to meet specific needs. This product has been tested according to the requirements of the USP-NF and has been found to meet these requirements.</p>

<p>Ivacaftor carboxylic acid is a pharmaceutical drug that is used to treat cystic fibrosis. It is a prodrug, which means it is inactive until it is metabolized by the body into its active form, ivacaftor. Ivacaftor carboxylic acid binds to CFTR proteins, which are responsible for transporting chloride ions across cell membranes. This causes an increase in the transport of chloride ions into cells and improves the flow of salt and water out of the lungs. Ivacaftor carboxylic acid has been shown to be safe and effective in patients with cystic fibrosis who have two copies of the F508del mutation in their CFTR gene, including those who have never received treatment with ivacaftor before.</p>

<p>2-Hydroxy-5-methylphenylbenzenepropanol is an aliphatic phenol that is used as a treatment for benzene poisoning. It is also used as a precursor to other compounds, such as the chlorides and alkylates of 2-hydroxy-5-methylphenylbenzenepropanol. This compound can be synthesized by reacting ethyl benzoylacetate with diisopropylamine in the presence of oxygen and chlorine gas. It is often immobilized using nutrients, l-tartaric acid, or cinnamic acid.</p>

<p>Cinacalcet impurity B is an amine that is a by-product of the manufacturing process for cinacalcet. This compound has been found to be active as a calcium sensitizer in vitro. The ionic form of this compound has been shown to bind to graphitic carbon and produce reproducible chromatographic peaks, which are characterized by their retention time and ionic strength. Cinacalcet impurity B has also been shown to have chiral properties, with the enantiomeric form being more active than the positional isomer. The affinity of this compound for chiral molecules may be due to its ability to act as a chiral selector.</p>

<p>Please enquire for more information about Simvastatin EP Impurity K including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Aztreonam Impurity B (AZTB) is a synthetic, non-natural impurity that has been identified in Aztreonam. The CAS number for AZTB is 102586-36-7. Aztreonam Impurity B TFA salt is an analytical standard with a purity of 99.9%. This product may be used as a drug product, research and development, or in the synthesis of other drugs. HPLC analysis of AZTB reveals an Rf value of 0.3 when eluted from a C18 column with water/acetonitrile gradient at 1 mL/minutes.</p>

<p>Topiramate impurity C is an analytical reference standard, which is primarily sourced from the chemical synthesis of topiramate-related compounds. With its ability to mimic the structural nuances of impurities found within topiramate formulations, it plays a crucial role in the quality control and validation processes within pharmaceutical development.Being essentially a byproduct or variant of the desired active pharmaceutical ingredient (API), Topiramate impurity C is employed in analytical methodologies to ensure the purity and efficacy of topiramate throughout its manufacturing and storage. Its mode of action involves acting as a comparator or calibrant in quantifying and identifying impurity profiles, thereby facilitating the optimization of synthesis pathways and purification methods.The uses and applications of Topiramate impurity C are integral to the comprehensive quality assurance frameworks in place within pharmaceutical laboratories. It ensures regulatory compliance by adhering to guidelines concerning permissible impurity thresholds, ultimately safeguarding patient safety and therapeutic efficacy. Through high-precision techniques like high-performance liquid chromatography (HPLC) and mass spectrometry, scientists can determine the stability, potency, and purity of pharmaceutical products with accuracy and reliability.</p>

<p>4-Chloro-4-methyl-5-methylene-1,3-dioxolan-2-one is a synthetic metabolite that is used as an impurity standard for the drug product 4-[4-(4,5-dichloro-1H,3H)-imidazolinyl]-N-[(dimethylamino)sulfonyl]benzamide. It is also used in analytical methods such as HPLC to measure the concentration of 4-[4-(4,5-dichloro-1H,3H)-imidazolinyl]-N-[(dimethylamino)sulfonyl]benzamide in a sample. This compound is also used in metabolism studies to study how it is broken down by the body.</p>

<p>Tolvaptan is a drug that is used for the treatment of hyponatremia. It is classified as an anti-diuretic, which blocks the release of water from the kidneys and can lead to increased levels of sodium in the blood. Tolvaptan has been shown to be metabolized by cytochrome P450 enzymes, forming the gamma-oxobutanoic acid impurity (tolvaptan-goc). This impurity has been found to have similar pharmacological activity to tolvaptan, but with a longer half-life. The gamma-oxobutanoic acid impurity may be detected in urine using HPLC techniques and can be used as an analytical standard or as a reference material for research and development purposes.</p>

<p>3,4-Dihydro naratriptan is a medicinal compound that is used as an anti-migraine drug. It is a hydrogenated form of the parent molecule naratriptan and has been shown to have a reaction time of about 30 minutes when catalyzed by palladium. The impurity, 3,4-dihydro naratriptan sulfonamide, has been found to be less potent than the target compound and can be eliminated from the synthesis by using catalytic hydrogenation. 3,4-Dihydro naratriptan sulfonamide can also be reduced by catalytic hydrogenation to yield 3,4-dihydro naratriptan.</p>

<p>N-[[Cis-4-(1-methylethyl)cyclohexyl]carbonyl]-D-phenylalanine (nateglinide impurity) is a postprandial blood glucose lowering agent that belongs to the class of glp-1 analogues. It has been shown to have long term efficacy and be safe for use in patients with bowel disease. Nateglinide is an ATP-sensitive K+ channel opener, which increases the amount of K+ permeability through the cell membrane and lowers the intracellular level of ATP. This leads to increased insulin release from beta cells in response to hyperglycaemia, which reduces blood glucose levels. Thermodynamic data for this compound have not been determined due to its low solubility in water.</p>

<p>N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is a drug product that is used as an HPLC standard. It has CAS No. 1618644-29-3 and a molecular mass of 309.35 g/mol. N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is an impurity in the synthesis of pyridostigmine bromide and is found in the urine of mice treated with this drug. This impurity can be determined by GC/MS and LC/MS techniques. N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is also found as a metabolite in rats and humans as well as being an analytical reference material for API impurities. The metabolite may be formed</p>

<p>Terbuchlor is a potent inhibitor of kinases, which are proteins that play a crucial role in cell signaling pathways. It is an analog of medicinal inhibitors used to treat tumors and cancer cells. Terbuchlor has been shown to induce apoptosis, or programmed cell death, in human cancer cells. In Chinese hamster ovary (CHO) cells, Terbuchlor has been found to inhibit the activity of several kinases involved in cellular proliferation and survival. This drug has potential as an anticancer agent due to its ability to target specific kinases involved in tumor growth and progression. Terbuchlor has also been detected in urine samples from patients receiving this medication, indicating its suitability for clinical use.</p>

<p>(6R)-Folinic acid is an impurity standard and a metabolite of folic acid. It is synthesized by the body in the liver, where it is converted to 5,10-methylenetetrahydrofolate (5,10-MTHF). This metabolite is used to convert homocysteine into methionine, which can then be converted into S-adenosylmethionine (SAMe), a compound that has been shown to have antidepressant properties. The methylation of folate also helps to regulate DNA synthesis and repair. (6R)-Folinic acid has been used in research as a drug development tool for studying folate metabolism and its effects on the central nervous system. High purity standards are available for use in HPLC analysis of this compound.</p>

<p>Sinalexin is an anticancer drug that targets human protein kinases. It is an analog of saxagliptin and has been shown to inhibit the growth of tumor cells in vitro. Sinalexin works by inhibiting the activity of protein kinases, which are enzymes that play a critical role in cell division and proliferation. In addition to its anticancer properties, Sinalexin has also been shown to induce apoptosis in cancer cells. This drug is excreted primarily in urine and has potential as a novel class of kinase inhibitors for the treatment of various types of cancer.</p>

<p>7-Hydroxy coumarin-13C is a metabolite of the drug 7-hydroxycoumarin, which is used as an impurity standard in the manufacture of some drugs. It has been synthesized and characterized by NMR, IR, and GC/MS spectroscopy. It has a purity of 99.9% or greater, and can be used for pharmacopoeia standards or as an analytical reference material.</p>

<p>Please enquire for more information about 6β-Hydroxy 21-acetyloxy budesonide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3,4-Dimethoxyphenyl isopropyl ketone (DMPK) is a calcium antagonist that has been shown to be hypotensive in rats. It is also used as a pharmacological agent to study muscle physiology and biotransformations. DMPK has been shown to have microbial uptake and chronotropic properties, which may explain its use in the treatment of bacterial infections. DMPK binds to sulfoxides and chiral compounds, blocking their activity by inhibiting the enzyme systems involved in oxidation reactions. The drug is an analog of benzyl alcohol, with which it shares similar pharmacological profile.</p>

<p>Defluoropitavastatin calcium salt is a synthetic, high purity, pharmacopoeia drug product. It is a metabolite of pitavastatin and has been shown to have similar pharmacological activity. Defluoropitavastatin calcium salt has a niche in the analytical industry due to its high purity and stability. It has been used as an impurity standard for HPLC analysis. Defluoropitavastatin calcium salt is not found in nature and can be synthesized with the help of our Custom Synthesis service.</p>

<p>2-Propylimidazole-4,5-dicarboxylic acid is an organic compound with the chemical formula CH2=C(CH3)CO2H. It is a colorless solid that has been found to have inhibitory activity against locomotor activity in mice. 2-Propylimidazole-4,5-dicarboxylic acid has also been shown to have anticancer properties. The fluorescence properties of this compound are due to the presence of two quinoid moieties, which can be excited by light at 350 nm and emit light at 500 nm. This compound also shows supramolecular interactions with other compounds, such as diethyl ester and n-dimethyl formamide. 2-Propylimidazole-4,5-dicarboxylic acid crystallizes in a monoclinic space group P21/c with four molecules per unit cell and a molecular weight</p>

<p>Fluocortolone Impurity 2 is a by-product of the synthesis of fluocortolone. It is an impurity in the drug product and is specific to HPLC standards. Fluocortolone Impurity 2 is an analytical standard, which may be used for research and development purposes or as a reference standard in pharmacopoeia. Fluocortolone Impurity 2 is an impurity found in the production of fluocortolone, which may be useful for research purposes or for high-purity drug development. Fluocortolone Impurity 2 has been shown to have therapeutic effects, including anti-inflammatory activities.</p>

<p>Please enquire for more information about (R)-L 888607 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about L-Piperacillin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Chlorpromazine EP Impurity F is a research and development impurity standard for the drug product, chlorpromazine. This product is synthesized in high purity and meets pharmacopeia standards. It has been shown to have low toxicity in animals, with no negative effects on the liver or kidneys. The metabolite of chlorpromazine EP Impurity F has been identified as being formed by hydrolysis of the ester linkage. Chlorpromazine EP Impurity F can be used as a reference material to support the quality control of drug products that contain chlorpromazine.</p>

<p>Please enquire for more information about 4-Ethyl-5-fluoropyrimidine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Benidipine 5-(1-benzylpiperidin-3-yl) is a potent calcium channel blocker that is used to treat hypertension. It contains mannitol and acts as a kinase inhibitor, which has been shown to have anticancer properties. Benidipine inhibits the growth of cancer cells by inducing apoptosis and suppressing protein synthesis. This drug has been studied extensively in Chinese medicinal research for its tumor-inhibiting effects, and it has demonstrated promising results in human urine samples. Benidipine is an analog of other medicinal inhibitors and has shown efficacy against various types of cancer cells.</p>

<p>3-[2-[(5-Ethyl-2-pyridinyl)ethoxy]phenyl] Pioglitazone Impurity is a drug product that is used for analytical purposes and as a research and development standard. It is an impurity of pioglitazone, a drug developed for the treatment of diabetes mellitus type II. The chemical name for 3-[2-[(5-Ethyl-2-pyridinyl)ethoxy]phenyl] Pioglitazone Impurity is 3-(4'-hydroxybutoxy)-4'-methoxyphenyl 2-(5'-ethyl-2'-pyridinylethoxy)benzeneacetic acid. This compound has an empirical formula of C20H25NO6 and molecular weight of 361.39 g/mol. The CAS number is 952187-99-4.</p>

<p>2-Ethoxy-4-[2-[[(1R)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid is a synthetic amino acid. It is used for research and development purposes, including the manufacture of pharmaceuticals. The impurity standard for this compound is CAS No. 147852-26-4. The drug product may be custom synthesized by our experienced chemists or it may be obtained from an established supplier. The purity of this compound is typically high, with purity levels exceeding 99%. This compound can also be used as a metabolite in metabolism studies, such as HPLC standards.</p>

<p>6-Hydroxymelatonin glucuronide is a metabolite of melatonin. It is an impurity in melatonin and can be used as a HPLC standard. This product is not intended for drug development, but it can be custom synthesized to meet specific needs. 6-Hydroxymelatonin glucuronide has CAS number 94840-69-4 and a molecular weight of 276.<br>6-Hydroxymelatonin glucuronide is a white powder with no odor or taste and should be stored at room temperature away from direct light.</p>

<p>Please enquire for more information about Decyclohexanol-ethoxycarbonyl-o-desmethyl venlafaxine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,4-Diamino-7-pteridinemethanol (2,4-DPPM) is a drug product and an impurity found in the synthesis of 2,4-diamino-7-(2H)-pteridinone. 2,4-DPPM is a synthetic product that can be used as an analytical standard for the determination of aminopyrine in pharmaceuticals and other organic compounds. This compound has been used in pharmacological studies to investigate its effects on various enzymes associated with metabolism. It has also been used as an impurity standard for HPLC analysis of aminopyrine.</p>

<p>Alfuzosin EP Impurity F hydrochloride is a drug product that is used as an analytical standard for Alfuzosin hydrochloride. It is a natural, synthetic, and impurity standard that exhibits similar chromatographic properties to the API. The CAS number of this impurity is 19216-68-3. This product has a niche market because it is used in metabolism studies. It also exhibits high purity and pharmacopoeia grade quality.</p>

<p>R-Amisulpride is an antipsychotic drug that has been shown to be effective in the treatment of schizophrenia. It is used as a long-term treatment for depression and other neurodegenerative diseases. R-Amisulpride also binds to gamma-aminobutyric acid (GABA) receptors, which are located on the outer surface of cells in the brain. This binding reduces the activity of these cells and leads to an increase in neurotransmitter release from presynaptic neurons, resulting in a sedative effect. R-Amisulpride is soluble in water and alcohol, but insoluble in ether or chloroform. It is metabolized by conjugation with glucuronic acid and sulphate, which results in its elimination from the body through urine.<br>R-Amisulpride can be found as white crystals or crystalline powder with a slightly bitter taste and odor. The drug is only available for oral administration at this time</p>

<p>15-HETE is a protein that has been found to be associated with cancer. It can be detected in urine and has been shown to have inhibitors that promote apoptosis, which is the natural process of programmed cell death. This inhibitor analog has been studied for its potential as an anticancer agent and has shown promise in inhibiting kinase activity, which is essential for tumor growth and replication. 15-HETE has also been used in Chinese medicinal practices for its potential anticancer properties. Further research is needed to fully understand the mechanisms by which 15-HETE works and how it can be used to combat cancer in humans.</p>

<p>N,N-dimethyl-2-[(3-methylphenyl)phenylmethoxy]ethanamine is a metabolite of amphetamine. It is a synthetic drug that is used in the research and development of drugs. Its chemical name is 2-[(3-methylphenyl)phenylmethoxy]N,N-dimethyl ethanamine. It is also known as 3,4-dihydroxyphenethylamine and N,N-dimethylamphetamine. This compound has been found to be an impurity standard in amphetamine products. The CAS number for this compound is 21945-86-8.</p>

<p>3alpha-Hydroxy pravastatin sodium salt is a white to off-white crystalline powder. It is used as an analytical standard for 3alpha-hydroxypravastatin and its metabolites. The CAS number is 81093-43-8, and the molecular weight of this compound is 467.6 g/mol. This product can be custom synthesized to meet your needs.</p>

<p>Gbr 12935 dimaleate is a research and development impurity standard. It is a synthetic, high purity, pharmacopoeia drug product. The CAS number for Gbr 12935 dimaleate is 1349767-56-1. Gbr 12935 dimaleate is used in Drug Development and Metabolism studies as an analytical standard. This compound is also used as a natural metabolite in HPLC standards.</p>

<p>3-[2-[4-(5-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a drug product that can be used as an analytical reference standard. It is a synthetic compound that is not found in nature and has CAS number 1199589-74-6. This compound has been synthesized by custom synthesis and it is an impurity standard for HPLC analysis. 3-[2-[4-(5-Fluoro-1,2-benzisoxazol-3 -yl)-1 -piperidinyl]ethyl]-6,7,8,9 -tetrahydro - 2 methyl - 4H - pyrido[1,2 -a]p</p>

<p>N-Methyl-4-phenylpiperidine is a synthetic drug that acts as a stimulant. It is a structural analog of the neurotransmitter acetylcholine and has been shown to have similar effects in knockout mice. N-Methyl-4-phenylpiperidine is metabolized by hydrolysis of the amide group, leading to the formation of alphaprodine and hydroxyphenylacetic acid. This drug has been shown to inhibit dopamine and serotonin uptake in rats, which may be related to its psychostimulant effects. Clinical pharmacology studies have shown that this drug can increase blood pressure, heart rate, and respiration rates in humans.</p>

<p>Please enquire for more information about Anhydrovinblastine N’B-oxide sulfate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl N-[(7R)-6,7-dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]carb amate is a synthetic compound. It is an impurity in the drug product Brivaracetam (CAS No. 1083065-09-1). This impurity was observed to be present in Brivaracetam at a concentration of 0.0008%. The drug product was manufactured by Drug development and Natural, Research and Development. The impurities were detected using HPLC standard and the analytical method. Impurity standards are available for the synthesis of this compound.</p>

<p>5-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one is a synthetic compound that has been used as an impurity standard. This substance is also found in the drug product Loxapine (Loxitane) and is metabolized to the active ingredient loxapine. 5-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one has not been shown to have any therapeutic effects.</p>

<p>Emtricitabine impurity 9 is an analytical standard that is used to calibrate HPLC instruments. It is a natural product, which is synthesized and purified. Emtricitabine impurity 9 can be custom-synthesized and is used in drug development research. This chemical compound has a purity of &gt;98% and a CAS number of 20752-33-4. The API impurity is the active pharmaceutical ingredient in the drug product, emtricitabine.</p>

<p>Leuprolide acetate ep impurity F is a drug product that is an impurity standard for the leuprolide acetate API. It is used in analytical and clinical studies to identify the presence of leuprolide acetate impurities, as well as to determine the metabolism of leuprolide acetate. Leuprolide acetate ep impurity F has been shown to be a natural metabolite of leuprolide acetate and have a niche application in pharmacopoeia.</p>

<p>aH 11110 Hydrochloride is an analytical standard for HPLC. It is a white powder that can be used to make up a solution of known concentration for use in HPLC analysis. It has been shown to have no pharmacological activity, and is not considered to be toxic. The impurity profile of aH 11110 Hydrochloride is similar to the corresponding impurity profile of the drug product, which is consistent with the chemical structure.</p>

<p>Please enquire for more information about Levothyroxine EP impurity B including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-O-methyl ivermectin is a drug product that is an analytical standard for the impurity 7-O-methyl ivermectin B1a. Impurity 7-O-methyl ivermectin B1a is a natural API that is found in the synthesis of Ivermectin. It has a CAS number of 90589-08-4 and is produced through custom synthesis. This impurity can be used as an analytical standard for HPLC methods, such as high purity and pharmacopoeia grade. 7-O-methyl ivermectin B1a has shown to have little or no activity against bacteria, fungi, or parasites.</p>

<p>Metabolite of benserazide</p>

<p>Regorafenib metabolite M5 is a drug product that is custom synthesized by our company and has high purity. It can be used in metabolism studies, drug development, and pharmacopoeia due to its natural origin. It is also a synthetic compound that can be used as an impurity standard or research and development standard in HPLC.</p>

<p>1,3-Bis-O-(tert-butyldimethylsilyl)-calcipotriene is a synthetic silyl ether of calcipotriene. It is used for the synthesis of drugs and as an impurity standard for HPLC analysis. 1,3-Bis-O-(tert-butyldimethylsilyl)-calcipotriene has been studied in metabolism studies and found to be natural, but it is not an API because it does not have a biological activity. It is also used in the development process of drugs and has been shown to be pharmacopoeia grade with a purity of at least 98%.</p>

<p>Desmethoxyamino hydroxy gemifloxacin is a drug product that belongs to the class of fluoroquinolones. It is a synthetic compound with a molecular weight of 551.4 g/mol and an empirical formula of C21H25FN3O2. Desmethoxyamino hydroxy gemifloxacin has been shown to inhibit bacterial DNA gyrase and topoisomerase IV in vitro, which are enzymes that maintain the integrity of bacterial DNA. The compound binds to 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. This drug product is metabolized into gemifloxacin, desmethoxyamino acid, and desmethylgemifloxacin. These metabolites have not been shown to be active against bacterial DNA gyrase or topoisomerase IV in vitro, but may be active against other targets in</p>

<p>Hydrocortisone impurity G is a hydrocortisone derivative that has been shown to be an inhibitor of the estradiol dehydrogenase, which is responsible for converting estradiol to estrone. It also inhibits the conversion of cortisol to cortisone and can thus be used as a model system in order to study the effects of corticosteroids on oxidation reactions. Hydrocortisone impurity G is present in animal products, such as meat, milk, and eggs, at concentrations of up to 2.5%. This impurity can also be found in vegetable oils and fats at concentrations of up to 1%. The presence of this compound has been confirmed by gas chromatography-mass spectrometry (GC-MS). Hydrocortisone impurity G is not known to have any adverse effects on humans.</p>

<p>Iferanserin is a medicinal analog that has shown promising anticancer activity. It is an inhibitor of kinase, a protein that plays a crucial role in cancer cell growth and tumor formation. Iferanserin induces apoptosis, or programmed cell death, in cancer cells by disrupting the cell cycle. This drug has been studied extensively in Chinese patients with various types of cancer and has shown significant antitumor effects. Iferanserin acts as a potent inhibitor of protein kinases, which are enzymes that regulate cellular processes such as gene expression, cell division, and differentiation. It is excreted primarily in urine and may have potential as a novel therapy for cancer treatment.</p>

<p>4-Desmethyl-4-ethylimidazolyl nilotinib is a synthetic drug product that is custom-synthesized for research and development purposes. This compound is a metabolite of nilotinib, an inhibitor of the tyrosine kinase ABL1 and BCR-ABL1. 4-Desmethyl-4-ethylimidazolyl nilotinib has been shown to be a substrate for CYP2C8, CYP2C9, CYP3A4, and CYP3A5. It has also been found to be an impurity in API standards of nilotinib.</p>

<p>Endo-cis-lurasidone hydrochloride is a synthetic, high purity, analytical standard material. It is an impurity in the drug product, Lurasidone hydrochloride. The chemical name for Endo-cis-lurasidone hydrochloride is 3-[4-(2,6-dioxopiperidin-3-yl)phenoxy]propanoic acid, 1-[(1R)-1-(2,3-dihydroxypropyl)piperidin-3-yl] ester. The CAS number for Endo-cis-lurasidone hydrochloride is 1318074-20-2.</p>

<p>Propoxyphenyl homohydroxysildenafil is a preparative mass spectrometric analysis of the metabolite of sildenafil, which is a phosphodiesterase type 5 inhibitor. It has been shown to increase the flow rate in rats with an experimental pulmonary hypertension. The product ions of propoxyphenyl homohydroxysildenafil are m/z 409.3, 417.2, and 419.2, and its pharmacological study has been conducted on tadalafil and isobutyl.</p>

<p>Please enquire for more information about Des(methylpiperazinyl) imatinib dimer piperazinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>NPS-ALX-4A is a drug, which has been shown to have cognition-enhancing effects in mice. It is a 5-HT6 receptor antagonist and can be used as an animal model for human cognitive disorders. NPS-ALX-4A was administered orally to control mice and the animals were tested for learning and memory. The study showed that NPS-ALX-4A improved spatial memory in the mouse model. This drug has not been tested on humans, but it has shown cognitive benefits in the mouse model with no significant side effects.</p>

<p>(3α)-Allopregnanolone sulfate is a medicinal compound with potential anticancer properties. It is an analog of the natural hormone allopregnanolone and has been shown to inhibit kinases involved in cancer cell proliferation and survival. This compound induces apoptosis, or programmed cell death, in cancer cells by targeting proteins that regulate cell growth and division. (3α)-Allopregnanolone sulfate has been studied as a potential inhibitor of tumor growth in human cancer cells and has shown promising results. It can be detected in urine samples and has also been used in Chinese traditional medicine for its medicinal properties.</p>

<p>Cefixime EP Impurity C disodium is an impurity in the drug Cefixime EP. It is a by-product of the synthesis process, which can be removed by a purification process. This product is an analytical standard and is used for qualitative analysis in HPLC. It is also used as a research and development standard for drug development. This product has been classified as a niche impurity since it only occurs at trace levels in the drug product, but it may have pharmacological relevance to some patients. This impurity can be synthesized from natural or synthetic sources and is available for custom synthesis to meet specific customer needs.</p>

<p>aR-C 66096 Tetrasodium is a drug product that has been developed for use in analytical, research and development, and other applications. The active ingredient of aR-C 66096 Tetrasodium is Metabolism studies (145782-74-7). It is a natural API impurity with CAS No. 145782-74-7. The impurity standard of this compound is Synthetic (145782-74-7). This product has been custom synthesized to meet the requirements of an Impurity Standard (145782-74-7). aR-C 66096 Tetrasodium is manufactured in the United States and meets all USP/EP specifications. aR-C 66096 Tetrasodium was developed to be used as an HPLC standard for pharmacopoeia testing.</p>

<p>Valdecoxib 3'-sulfonamide is a synthetic, non-naturally occurring drug product that has been custom synthesized for the purposes of research and development. It is not a natural API nor is it an impurity standard. This compound has been developed as a new lead compound for pharmacological studies and drug development, with an emphasis on high purity standards. The CAS number for this compound is 1373038-56-2.</p>

<p>tert-Butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate is an impurity that is found in the production of tert-butyl 4-(4,5,6,7,8,9,10-hexahydrobenzo[a]pyrido[1,2:4,3]triazin-2(3H)-yl)piperazine-1 carboxylate. It has been used as a reference standard for HPLC. This compound is not active when administered orally and does not exhibit any pharmacological activity.</p>

<p>O-Desmethyl mycophenolate mofetil (ODMM) is a metabolite of mycophenolic acid, a drug that is used to treat immunosuppressive diseases. ODMM can be synthesized in the laboratory and used as an analytical standard for mycophenolic acid and its metabolites. ODMM is also a metabolic product of mycophenolate mofetil, which has been shown to have anti-inflammatory properties.</p>

<p>Cyamemazine sulfoxide is a histamine H1 receptor antagonist. It has been shown to have strong affinity for the serotonin 5-HT2C and dopamine D2 receptors, as well as the atrial 5-HT2A receptors. Cyamemazine sulfoxide has a low oral bioavailability of about 10% and is metabolized in the liver to cyamemazine and its active form, cyamemazine sulfoxide. Cyamemazine sulfoxide binds to serotonin 5-HT2C receptors with a high affinity, which leads to inhibition of serotonin release from nerve endings in the brain. This drug also inhibits dopamine release from nerve endings in the brain and has been shown to have cardiac effects on heart rate and contractility.</p>

<p>9-Epimitomycin B is a water-soluble, alkoxy-substituted amino compound that is used medicinally. It has antibacterial activity and has been shown to be effective against Gram-positive bacteria such as Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis. 9-Epimitomycin B inhibits the growth of these bacteria by binding to their ribosomes and inhibiting protein synthesis. The carbon atoms in 9-epimitomycin B are linked to an alkoxy group at one end, which causes it to have a higher affinity for bacterial ribosomes than human ribosomes. 9-Epimitomycin B also binds to mitomycin C, which may be responsible for its antimetabolite properties.</p>

<p>Lidocaine is a local anesthetic that inhibits the transmission of nerve impulses. Lidocaine-d10 hydrochloride is a drug product that contains lidocaine and deuterium-labeled lidocaine, which has been chemically synthesized to contain deuterium atoms in place of hydrogen atoms. Lidocaine-d10 hydrochloride is used as an analytical standard for pharmacological studies and drug development. It also serves as an impurity standard in the synthesis of other compounds. Lidocaine-d10 hydrochloride is metabolized through oxidation and reduction, forming metabolites such as 4-hydroxylidocaine, 4-dehydroxylidocaine, and 2,6-dehydroxylidocaine.<br>Lidocaine-d10 hydrochloride can be used to study the metabolism of lidocaine and its metabolites, which are important for drug development.</p>