APIs for research and impurities

<p>Ajoene is a natural compound that has been shown to have antimicrobial properties, as well as an ability to inhibit the growth of tumor cells. Ajoene is also a potent inhibitor of dextran sulfate proteoglycan synthesis in vitro and has been shown to produce a hypoglycemic effect in vivo. Ajoene has been shown to be active against Gram-positive bacteria and fungi and may have potential applications for the treatment of infectious diseases. Further research is needed to determine whether ajoene may be used as an antioxidant or neuroprotective agent.</p>

<p>N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride is an impurity in the synthesis of N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N'-methylpropylenediamine formamide hydrochloride. It is a white solid that can be used as an analytical reference standard for HPLC. It has been detected in the urine of people taking this drug and can be used to identify the presence of this drug in urine samples.</p>

<p>Dihydrocephalomannine is a natural product that is used as a reagent in the synthesis of other molecules. It can be found in plants such as Taxus brevifolia, which contains the molecule taxol. Dihydrocephalomannine is synthesized by benzoylation and hydroxylation of dihydrobenzofuran. The molecule has been shown to have cytotoxic activity against human ovarian cancer cells, but its mechanism of action is not yet known.</p>

<p>Probimane is an anticancer drug that belongs to the class of kinase inhibitors. It is a synthetic analog of the Chinese herb, curcumol, and has been shown to inhibit the growth of tumor cells in vitro and in vivo. Probimane targets cyclin-dependent kinases (CDKs) and other protein kinases involved in cell cycle regulation, leading to apoptosis or programmed cell death. This drug has demonstrated potent activity against a range of human cancer cell lines, including breast, lung, and colon cancer. Probimane has also been found to be excreted in urine, making it a potential candidate for non-invasive monitoring of treatment efficacy.</p>

<p>Desgadolinium gadoteridol is a contrast agent that is used in magnetic resonance imaging (MRI). It is a gadolinium-based contrast agent that contains an ester linkage. The chelate complex of gadolinium with desgadolinium has been shown to have high water permeability and target tissue affinity, as well as low toxicity. Desgadolinium gadoteridol is used to diagnose inflammatory bowel diseases by determining the thickness of the bowel wall. This agent may also be used to evaluate blood pressure and diagnose hemorrhoids or colorectal polyps.</p>

<p>iso-Gemfibrozil is a natural, synthetic drug product. It is an impurity standard for the pharmacopoeia and analytical standards for HPLC. iso-Gemfibrozil is metabolized in the liver to its active form, gemfibrozil. Impurities are not detected by HPLC and can be found in low levels in the API impurity standard. It has been used as a research and development candidate in clinical studies on atherosclerosis, hyperlipidemia, and diabetes mellitus.</p>

<p>2,6-Dichlorophenyl carbonimidic dichloride is an analytical reference material that is used as a high purity and drug development API impurity standard. The compound has been found to be a metabolite of the anti-inflammatory drug ibuprofen. It is also used as a pharmacopoeia impurity standard in the United States, Japan, and Europe. CAS No. 21709-18-2 is the assigned number for this compound.</p>

<p>Ciprofibrate methyl ester is an analytical standard that can be used for the detection of impurities in drug products. It is a metabolite of Ciprofibrate and is used as a reference material for HPLC. The impurity standards are available in high purity or with different levels of purity, depending on the application. In addition, it can be custom synthesized to meet specific needs. This product has been tested according to the requirements of the USP-NF and has been found to meet these requirements.</p>

<p>D-Ribose-3-D is a medicinal compound that has been shown to have anti-cancer properties. It is an inhibitor of kinases, which are enzymes that play a critical role in cancer cell growth and proliferation. D-Ribose-3-D has been found to inhibit the growth of human cancer cells and induce apoptosis, or programmed cell death, in these cells. This compound has also been studied for its potential use as an anticancer drug and has shown promising results in Chinese hamster ovary cells. Additionally, D-Ribose-3-D has been investigated for its potential use as an inhibitor of acetylcholinesterase, the enzyme targeted by donepezil in the treatment of Alzheimer's disease. Overall, D-Ribose-3-D holds great promise as a potent and effective medicinal compound with a wide range of potential applications.</p>

<p>7-(3-Bromopropoxy)-3,4-dihydrocarbostyril is a white crystalline powder that is soluble in ethanol and ether. It is used as an analytical standard in HPLC or GC, as well as in the development of drugs. 7-(3-Bromopropoxy)-3,4-dihydrocarbostyril has a purity of 99% and is available for custom synthesis with a minimum order quantity of 50 grams. This compound can be synthesized from natural or synthetic sources.</p>

<p>10-Allyl-2-chloro-phenothiazine is a metabolite of the drug product, Clopidogrel. It is a white crystalline powder that is soluble in water and alcohol. 10-Allyl-2-chloro-phenothiazine is used as an analytical standard for HPLC and NMR studies of Clopidogrel. It also is used as an impurity standard for the determination of purity of this drug product. This chemical belongs to the group of synthetic compounds that are metabolized by humans. Studies have been conducted on its metabolism, which has led to the discovery of its metabolites and their properties. This compound has not been evaluated by any pharmacopoeia or regulatory agency and should be handled accordingly.</p>

<p>Pyrene-13C6 is a medicinal compound that has been shown to be an effective inhibitor of apoptosis in tumor and leukemia cells. It works by inhibiting the activity of certain kinases and proteins involved in cell cycle regulation, which can lead to the death of cancer cells. Pyrene-13C6 has been tested extensively in Chinese hamster ovary cells and has been found to have potent anticancer activity. In addition, this compound has been detected in human urine, suggesting that it may have potential as a diagnostic tool for cancer detection. Overall, Pyrene-13C6 is a promising candidate for the development of new cancer therapies and diagnostic methods.</p>

<p>4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid (4BMBCA) is a chemical compound that is used as an analytical method in drug discovery and development. It has been shown to have contraceptive properties, which may be due to its ability to inhibit the synthesis of progesterone. 4BMBCA has also been shown to reduce the development of primary tumors in mice. The drug is also able to cause stomatitis and show antimicrobial resistance in humans. Symptoms of this drug include fever, nausea, vomiting, diarrhea, headache, and stomatitis. 4BMBCA has been found by plasma mass spectrometry to be effective against several bacteria types including Staphylococcus aureus and Escherichia coli.</p>

<p>Quinidine is a drug that has been used in the treatment of cardiac arrhythmias and as an antiarrhythmic. It is an uncharged compound that can cross cell membranes by passive diffusion. Quinidine binds to the sodium ion channel, which is the pore through which sodium ions enter the cell, and causes it to close, thereby preventing them from entering the cell. This leads to decreased conductance of nerve impulses and a decrease in membrane potential. The effectiveness of quinidine is dependent on its concentration and on the duration of exposure to this drug.</p>

<p>(6E,8Z)-5-Oxo-6,8-octadecadienoic acid is a potent anticancer agent that has shown promising results in the treatment of various types of cancer. It works as an inhibitor of tumor growth by inducing apoptosis and inhibiting the cell cycle progression. This compound has been extensively studied in Chinese medicinal practices and has been found to be effective against cancer cells. It acts as a protein kinase analog, which makes it a valuable tool for studying the signaling pathways involved in cancer development. Additionally, this compound can be detected in human urine and may serve as a potential biomarker for cancer diagnosis and monitoring. Overall, (6E,8Z)-5-Oxo-6,8-octadecadienoic acid holds great promise as a therapeutic agent for the treatment of cancer.</p>

<p>N-Methyl-4-phenylpiperidine is a synthetic drug that acts as a stimulant. It is a structural analog of the neurotransmitter acetylcholine and has been shown to have similar effects in knockout mice. N-Methyl-4-phenylpiperidine is metabolized by hydrolysis of the amide group, leading to the formation of alphaprodine and hydroxyphenylacetic acid. This drug has been shown to inhibit dopamine and serotonin uptake in rats, which may be related to its psychostimulant effects. Clinical pharmacology studies have shown that this drug can increase blood pressure, heart rate, and respiration rates in humans.</p>

<p>Olsalazine sodium impurity A is a synthetic drug that is used as an active pharmaceutical ingredient (API) in the development of drug products. It is a metabolite of olsalazine sodium, which is a natural product. Olsalazine sodium impurity A has been shown to be an analytical impurity for HPLC standards and is also used in metabolism studies. This impurity has niche applications as an analytical standard or as a pharmacopoeia reference material.END&gt;</p>

<p>Famotidine is a pharmaceutical agent that belongs to the class of H2-receptor antagonists. It is used for the treatment of peptic ulcers and gastroesophageal reflux disease. Famotidine inhibits gastric acid secretion by blocking the H2-receptors in the parietal cells in the stomach. There are two major impurities, 4-amino-N-[(4-[[[2-(aminosulphonyl)thiazol-4-yl]methyl]sulphanyl]ethyl]-3,5-bis[[2-[(aminoiminomethyl)amino]thiazol-4-yl]methyl]sulphanyl]ethyl]-1,2,4,6-thiatriazine 1,1 dioxide and 2-[(aminoiminomethyl)amino]-N-[(4-[[2-(aminosulphonyl)thiazol-4-yl</p>

<p>Ethylenediamine p-toluenesulfonate is an inhibitor of various kinases that have been implicated in cancer cell replication and tumor growth. This chemical compound has been shown to induce apoptosis, or programmed cell death, in human cancer cells. Ethylenediamine p-toluenesulfonate has also been studied as a potential treatment for methotrexate-induced nephrotoxicity, a common side effect of chemotherapy. Additionally, it has been identified as a potent analog of astaxanthin, which is a naturally occurring carotenoid with antioxidant properties. The use of ethylenediamine p-toluenesulfonate as a kinase inhibitor may hold promise for the development of novel cancer therapies.</p>

<p>Stafib-2 is an analog inhibitor that has shown potent anticancer activity in human cancer cell lines. It works by inhibiting kinases, which are enzymes that play a key role in regulating cell growth and division. Stafib-2 has been shown to induce apoptosis, or programmed cell death, in Chinese hamster ovary cells and human cancer cells. This drug also inhibits the activity of elastin kinase, a protein that is involved in tumor growth and metastasis. Stafib-2 has potential as a targeted therapy for cancer treatment due to its ability to selectively inhibit specific kinases involved in cancer progression. Its unique mechanism of action makes it a promising candidate for further development as an anticancer agent.</p>

<p>9-(1,3-Dioxolan-2-ylmethyl)-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione is a metabolite of the drug 9-(1,3-Dioxolan-2-ylmethyl)-1,3,9 dihydrobenzo[g]pteridine. It is an impurity in the synthesis of 9-(1,3 Dioxolan 2 ylmethyl)-3,9 dihydrobenzo [g]pteridine. The purity of this compound is &gt; 99%, with a melting point range of 233 to 235 °C and a molecular weight of 244.24 g/mol. It is soluble in methanol and acetonitrile. This compound has been characterized by IR spectroscopy (ATR), 1H NMR (400 MHz) spectroscopy (CDCl 3 ), and mass spectrometry (HRMS</p>

<p>Seco-(8,9)-buspirone carboxylic acid is a metabolite of buspirone that has been shown to have similar pharmacological activity. Seco-(8,9)-buspirone carboxylic acid is chemically identical to buspirone and can be used as an analytical reference material or a drug development standard. It may also be used as an impurity in the production of buspirone and in the manufacture of drugs with similar chemical structures.</p>

<p>Lamotrigine is a chemically unrelated compound, which is the active ingredient of a new class of adjuvant drugs for epilepsy. This drug has been found to be effective against seizures in patients with partial seizures and generalized seizures. Lamotrigine is an orally administered suspensoid that can be mixed with water or other liquids to form a suspension. It has been used as a flavouring agent and an adjuvant in pharmaceuticals, including tablets and capsules. The chemical structure of lamotrigine includes two 2,3-dichlorophenyl groups connected by an amino group (guanidinoimino). This structure gives lamotrigine its chemical name: 2-(2,3-dichlorophenyl)-2-(guanidinoimino) acetonitrile.</p>

<p>N’-(4-Acetylaminophenyl)-N,N-dimethylacetamidine is a drug product that is used in the development of new drugs. It has high purity, analytical grade and natural origin. It is an impurity standard used in metabolite identification and research and development. The CAS number for this compound is 1358054-66-6.</p>

<p>Pinoxaden is a protein kinase inhibitor that has shown promising results in the treatment of cancer. It specifically targets cyclin-dependent kinases, which are key regulators of cell division and proliferation. By inhibiting these kinases, Pinoxaden induces apoptosis (programmed cell death) in cancer cells, thereby preventing tumor growth and metastasis. This drug is an analog of a Chinese herbal medicine and has been shown to have potent anticancer activity both in vitro and in vivo. In addition, Pinoxaden has low toxicity and is excreted primarily through urine, making it a promising candidate for further development as an anticancer agent.</p>

<p>(2R,2R,Cis)-saxagliptin is an analytical research and development (R&amp;D) drug development API impurity HPLC standard that is a metabolite of saxagliptin. Saxagliptin is a drug product that has been approved for the treatment of type 2 diabetes. It has been shown to inhibit the activity of dipeptidyl peptidase-4 (DPP-4) in vitro and in vivo. Saxagliptin is a competitive inhibitor of DPP-4, which prevents it from breaking down incretin hormones such as glucagon-like peptide 1 (GLP-1). This results in increased levels of GLP-1, which improves blood glucose control. The purity level for this API impurity HPLC standard is high. Impurities are less than 0.5% and have been tested at various concentrations to ensure quality standards are met.</p>

<p>Erythromycin EP impurity L is a metabolite of erythromycin that is found in the urine of patients taking erythromycin. It is a white to light yellow crystalline powder. Erythromycin EP impurity L has been used as an analytical standard for HPLC and GC-MS, and as a pharmacopoeia reference material. Erythromycin EP impurity L is also known to have anti-inflammatory properties.</p>

<p>N-Methyl carvedilol hydrochloride is a drug product that is an analytical standard for the impurity N-methylcarvedilol. The CAS number for this compound is 1346599-33-4. It is a metabolite of the drug Carvedilol, which is used to treat heart failure and high blood pressure. Metabolism studies have been conducted in rats and humans, and it has been shown that both animals and humans metabolize carvedilol to produce N-methylcarvedilol as a major metabolite. This product is available as a custom synthesis or can be purchased from one of our suppliers who specialize in providing synthetic standards. We offer this product at high purity levels with HPLC purity and pharmacopoeia specifications.</p>

<p>Meclofenamate sodium hydrate is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenase, lipoxygenase, and phospholipase A 2 . It has been shown to be effective in the treatment of many diseases such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and gout. Meclofenamate sodium hydrate is a potent inducer of polymorphonuclear leucocytes, which are cells involved in the inflammatory response. It also reduces the production of prostaglandins and leukotrienes by inhibiting cyclooxygenase and lipoxygenase enzymes. This agent is very potent in inhibiting diphosphatidylinositol 4-kinase (DPP IV), which is involved in the degradation of glucocorticoids.</p>

<p>N-Boc-4-azido-L-homoalanine (dicyclohexylammonium) is an impurity that may be found in drugs. It is a synthetic compound with CAS number 1217459-14-7. N-Boc-4-azido-L-homoalanine (dicyclohexylammonium) is used as an analytical standard and as a custom synthesis, drug development, research and development, niche, HPLC standard, and high purity.</p>

<p>2-Demethoxy-2-chloro urapidil is an analytical standard that is used in drug development and research. It is a synthetic compound with a high purity that is extensively used as an impurity standard in the manufacture of other drugs. The CAS number for 2-demethoxy-2-chloro urapidil is 34661-73-9.</p>

<p>Sodium sulfoxone is a sulfa drug that is used in the treatment of a number of conditions, including cancer and inflammatory skin diseases. It works by blocking the synthesis of DNA and RNA in bacterial cells, thereby inhibiting cell growth. Sodium sulfoxone has been shown to be effective against a wide variety of microorganisms, including Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes and Enterococcus faecalis. Sodium sulfoxone can also be used as an eye drop to treat eye disorders such as choroidal neovascularization.</p>

<p>Kaempferol di-O-methoxymethyl ether is a natural product that has been identified as a metabolite of kaempferol. It is an API impurity in the drug product and can also be found in the synthesis of kaempferol. Kaempferol di-O-methoxymethyl ether is a synthetic compound that can be used for drug development, research and development, and analytical purposes. It is an HPLC standard for pharmacopoeia.</p>

<p>Carbidopa Impurity 2 is an impurity of carbidopa, a drug product that is used to treat Parkinson's disease. Carbidopa Impurity 2 is an analytical standard for the identification and quantification of carbidopa in biological samples. The natural form of this compound is unknown, but it has been synthesized using custom synthesis techniques. This compound was also used to develop a high purity HPLC standard and as a pharmacopoeia reference material.</p>

<p>Telmisartan is a drug that belongs to the class of angiotensin II receptor antagonists and is used in the treatment of hypertension. Telmisartan can be quantitatively analyzed with high sensitivity by liquid chromatography. Impurities in telmisartan can be analyzed qualitatively and quantitatively by liquid chromatography, which requires a shorter time than GC analysis.</p>

<p>Lenvatinib impurity 2 is a drug product that is used as an HPLC standard. It is a natural metabolite of lenvatinib, which is developed for the treatment of various types of cancers. The compound has been shown to inhibit the growth of human tumor cells and induce apoptosis in cell lines.<br>Lenvatinib impurity 2 is a synthetic compound that can be custom synthesized to meet specific requirements and needs. It has been found to have pharmacological effects similar to those of lenvatinib, but with less toxicity.<br>Lenvatinib impurity 2 can be used as an analytical or API impurity for the development, research and analysis of lenvatinib-based drugs. This compound has also been found to be useful in metabolism studies when testing for potential adverse reactions due to its similarity with lenvatinib.</p>

<p>4-[2-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methylpyridinium Chloride Monohydrochloride is a drug product under development for the treatment of bacterial infections. 4-[2-[(6R,7R)-7Amino--2carboxy8oxo5thia1azabicyclo[4.2.0]oct2en3yl]thio]-4thiazolyl]-1methylpyridinium Chloride Monohydrochloride is an impurity in the API Methicillin (CAS No. 40082764). Impurities are not necessarily undesirable and may have substantial therapeutic value or provide a desired</p>

<p>Loxoprofen Related Compound 2 is a mixture of diastereomers that is an impurity in the drug product, Loxoprofen. Loxoprofen Related Compound 2 is a metabolite of loxoprofen and its concentration in blood plasma after administration of loxoprofen can be used as an indicator for pharmacokinetics. The compound has been shown to inhibit the activity of bacterial dna gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. Loxoprofen Related Compound 2 was found to be less active than loxoprofen against MRSA and Clostridium perfringens, although it was more active than loxoprofen against Mycobacterium tuberculosis, Mycobacterium avium complex, and methicillin-resistant Staphylococcus aureus (MRSA).</p>

<p>4-Descyano-4-bromo-letrozole is a white crystalline powder with a purity of 99.5% or greater. This product is used as an analytical reference standard in the detection of impurities in pharmaceutical products and as a research and development intermediate in the synthesis of other organic compounds. 4-Descyano-4-bromo-letrozole is a metabolite that can be produced by cytochrome P450 enzymes, such as CYP1A2, CYP3A4, and CYP3A5. The chemical name for this drug product is 4-[(2,6-dichlorophenyl)amino]-4-[(2,6-dichlorophenyl)amino]benzoic acid bromide. CAS No. 143030-54-0</p>

<p>L-Threo-hex-2-enaric acid 1,4-lactone 6-methyl ester is a research and development compound. It is a metabolite of the drug product L-Threo-hex-2-enaric acid 1,4-lactone 6-(2,6,6)-trimethyl ester. L-Threo-hex-2-enaric acid 1,4-lactone 6-(2,6,6)-trimethyl ester (LTA) is an impurity in the drug product that is present as a result of its synthesis. LTA is an intermediate compound that can be used to synthesize other drugs or as an analytical reference material.</p>

<p>b-1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine is a drug product that is used in the development of drugs. It is a metabolite of cyclizine and has been shown to have antihistaminic effects. This chemical compound is an impurity standard for HPLC analyses of other substances. b-1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine has also been shown to be a synthetic intermediate in the synthesis of pharmaceuticals.</p>

<p>(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide is an analytical standard that is used as an impurity in the synthesis of a drug product. The purity of this compound is greater than 99%. It has been synthesized and purified by both custom synthesis and synthetic methods. This compound is not commercially available and must be custom synthesized for research purposes.</p>

<p>5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is an impurity found in the synthetic process of iopamidol. It is a nonionic chemical that has been shown to be synthesized using the following methods: dichloride and synthetic. 5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is used as a contrast agent for magnetic resonance imaging (MRI).</p>

<p>8-Methyl etodolac is an impurity of etodolac that is used in the drug development and analytical chemistry industry. It is a synthetic metabolite of etodolac, which is an analgesic agent that belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). 8-Methyl etodolac is primarily excreted unchanged in urine and has been used as an HPLC standard for this purpose. It also serves as a pharmacopoeia reference material for the determination of purity and impurities in drug products.</p>

<p>tert-Butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate is an impurity that is found in the production of tert-butyl 4-(4,5,6,7,8,9,10-hexahydrobenzo[a]pyrido[1,2:4,3]triazin-2(3H)-yl)piperazine-1 carboxylate. It has been used as a reference standard for HPLC. This compound is not active when administered orally and does not exhibit any pharmacological activity.</p>

<p>Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the production of prostaglandins, which are produced by inflammatory cells in response to tissue injury. It is used to treat pain and inflammation. Aceclofenac is absorbed quickly from the gastrointestinal tract and has a high bioavailability. The maximum plasma concentration is reached within 1 hour after oral administration. Aceclofenac has a short half-life of about 2 hours. This drug binds to fatty acids and hepatoprotective substances, such as polymers, pyruvic transaminase, acetate extract, and humans. It also inhibits the transcription of cyclooxygenase-2 (COX-2), which produces prostaglandins that are involved in various aspects of inflammation.</p>

<p>Mandelic acid is a naturally occurring organic compound that is the simplest aromatic carboxylic acid. It is used as an intermediate in chemical synthesis, and as a reagent in analytical chemistry. Mandelic acid can be produced synthetically by the oxidation of benzaldehyde or benzoic acid. Mandelic acid has been shown to inhibit the metabolism of many drugs, including diazepam, phenobarbital and propranolol. It also shows anti-inflammatory effects due to its ability to inhibit prostaglandin synthesis.</p>

<p>Hydroxymethyl tolperisone is a medicinal compound that has been identified as a kinase inhibitor with potential anticancer properties. It has shown promising results in inhibiting the growth of leukemia cells and tumor cell lines in human studies. Hydroxymethyl tolperisone works by interfering with protein synthesis, disrupting the cell cycle, and inducing apoptosis in cancer cells. This compound has also been found to be effective against various types of cancer, including breast, lung, and colon cancer. Hydroxymethyl tolperisone is an analog of tolperisone, a muscle relaxant that is excreted primarily through urine. The use of this compound as an anticancer agent is still under investigation, but it holds great promise for the future of cancer treatment.</p>

<p>Please enquire for more information about 1-(4-Methyl-2,5-dioxoimidazolidin-4-yl)urea including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzenepropanoic acid ethyl ester is an analytical standard for metabolite identification and quantitation in human urine. It is a natural product, API impurity, or synthetic. This compound is used as a drug development tool to study metabolism studies and may be used as a custom synthesis or impurity standard. 4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzenepropanoic acid ethyl ester may be used in HPLC analysis to produce high purity and pharmacopoeia standards.</p>

<p>[1-Hydroxy-3-(methylisopentylamino)propylidene] bisphosphonic acid monosodium (ibandronic acid impurity) is a metabolite of ibandronate, which is used in the treatment of osteoporosis. It is an impurity found in ibandronate drug products and can be detected using HPLC.</p>

<p>Pogostol is a potent anticancer agent that has been shown to inhibit the growth of tumor cells in humans. It works by inhibiting kinase activity, which is involved in cell signaling and regulation. Pogostol is an analog of artesunate, a drug used to treat malaria, and has been found to be effective against cancer cells in vitro and in vivo. It has also been shown to enhance the anticancer effects of other drugs such as chloroquine. Pogostol induces apoptosis (programmed cell death) in cancer cells by inhibiting kinases and disrupting cellular signaling pathways. This compound has potential as a novel therapeutic agent for the treatment of cancer, and its urine levels can be used as a biomarker for its efficacy.</p>

<p>Please enquire for more information about 2-Benzoylbenzene-1-sulfonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Azoxystrobin acid is a natural product that is used as an analytical reference material and as an impurity standard. Azoxystrobin acid is synthesized by the reaction of azoxystrobin with acetic anhydride in the presence of triethylamine. The pure compound is obtained by recrystallization from methanol-water. Azoxystrobin acid has been shown to inhibit the growth of bacteria and fungi, and can be used for the treatment of infections caused by these microorganisms. Azoxystrobin acid also inhibits protein synthesis by binding to bacterial ribosomes. It has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.</p>

<p>N-[4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]phenyl]-acetamide is a synthetic drug product that belongs to the class of drugs called acetamides. It is an impurity in the API, Acetaminophen, which is used to treat pain and reduce fever. N-[4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]phenyl]-acetamide is also used as a research and development chemical for drug discovery. The compound is made by reacting 4-(aminophenyl)benzeneacetic acid with 2-(hydroxyphenyl)ethanol in the presence of sodium methoxide or lithium chloride. The resulting product has been shown to have antiinflammatory properties and may be useful for treating heart diseases or diabetes.</p>

<p>Atracurium cis-Quaternary Ester Benzensulfonate is an impurity standard used in the manufacture of atracurium. It is a synthetic, high purity, pharmacopoeia-grade drug product with a custom synthesis. Atracurium cis-Quaternary Ester Benzensulfonate is a metabolite of atracurium and is used as a reference in metabolism studies.</p>

<p>Please enquire for more information about Loxoprofen methyl-d3 ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Rotigotine is a drug that belongs to the group of pharmaceutical formulations. It is an unlabeled drug that has been shown to be effective in the treatment of depression. Rotigotine may be administered through a transdermal patch or by iontophoresis, which is a technique used to administer drugs through the skin. The mechanism of action is not known, but it may involve the inhibition of monoamine reuptake and/or alteration of intracellular levels of catecholamines. Rotigotine sulfate has a high affinity for dopamine receptors and increases plasma concentrations of dopamine by inhibiting its reuptake into presynaptic neurons. This leads to increased concentrations of dopamine in synaptic clefts and an increase in postsynaptic receptor binding.</p>

<p>5-O-Desethyl amlodipine is a metabolite of amlodipine. It has been used as an analytical reference standard for the determination of amlodipine and its metabolites in human plasma and urine. 5-O-Desethyl amlodipine has been reported to be excreted in human breast milk at a concentration that is about 20% of that found in maternal plasma. The drug product is manufactured by HPLC and is classified as a high purity pharmaceutical drug, which means it is free from extraneous substances such as other drugs, proteins, or bacteria.</p>

<p>1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,6-diol is an analytical standard in the form of a white solid. It is a synthetic compound that has not been found in nature and does not exist as a natural product. It is used to provide a calibration or quality control for HPLC testing. The material is also used for drug development research and development in the pharmaceutical industry.<br>1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,6-diol (CAS No. 1312706-19) is an analytical standard in the form of a white solid. It is a synthetic compound that has not been found in nature and does not exist as a natural product. It is used to provide</p>

<p>2-[3-[4-(3-Chloro-4-ethylphenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one is a research and development impurity standard. Impurities are the substances that are not intentionally added to the drug product but can be generated from the synthesis process or from the raw materials. This substance has been used as a synthetic intermediate in the production of other drugs and as an analytical reference for HPLC analysis. It is used to help develop new drugs by providing data about metabolites and possible toxic effects on humans.</p>

<p>2-[(Tetrahydropyran-2-yl)oxy]ethyl p-toluenesulfonate is a drug product. The compound is an impurity in the API, which is a metabolite of the synthetic chemical 2-[(Tetrahydropyran-2-yl)oxy]ethyl p-toluenesulfonate (CAS No. 65338-95-6). This impurity has been identified by HPLC analysis and was found to have natural origin. It has been detected in various batches of the API, although at different concentrations. It may also be present as an analytical or impurity standard for HPLC analysis.</p>

<p>N-Formyl-L-leucine (3S,4S,6S)-3-hexyltetrahydro-2-oxo-6-undecyl-2H-pyran-4-yl ester is a synthetic compound that has been used as an impurity standard and as a pharmacopoeia. It is also used in drug development and metabolism studies. The CAS number of this compound is 130676-65-2. HPLC analysis of this compound is available upon request.</p>

<p>1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate is a drug product that has been formulated as an HPLC standard and is used in drug development and research. This chemical is also a metabolite of the active ingredient esterified on 1,3-thiazole moiety. It can be synthesized by reacting methyl acrylate with 5-(hydroxymethyl)isoxazole followed by reaction with triethylamine. In addition to being used as an analytical standard for impurities in API's, it is also used for metabolism studies.<br>Molecular Formula: C24H31N3O4S<br>Molecular Weight: 441.53<br>CAS Number: 1010808-43-1</p>

<p>Lamivudine acid is a synthetic orotate prodrug that is converted to the active form, lamivudine. It inhibits the synthesis of viral DNA by inhibiting the reverse transcriptase enzyme and has been used as a treatment for HIV infection. Lamivudine acid is soluble in organic solvents such as acetone and cyclohexane. The crystal structure of this compound has been determined using X-ray crystallography and exhibits a zwitterion structure with a hydrogen bond between the carboxylate group and the amide nitrogen atom of the molecule.</p>

<p>1-(2-Deoxy-beta-D-xylofuranosyl)-5-methyluracil (1DXP) is a nucleoside that inhibits the enzyme UDP glucose pyrophosphorylase. This enzyme is involved in the synthesis of uridine nucleotides, which are required for RNA and DNA synthesis. 1DXP has been shown to be effective against hepatitis B virus and lymphocytic leukemia cells in vitro. The mechanism of action of 1DXP is not well understood, but it may be related to the inhibition of protein synthesis or cellular metabolism. It may also inhibit the enzyme amino transferase, which is important for the synthesis of aromatic amino acids such as phenylalanine and tyrosine.</p>

<p>2-Hydroxy-5-[2-[4-[[(6-methyl-2-pyridinyl)amino]sulfonyl]phenyl]diazenyl]benzoic acid is a synthetic drug product that has not been approved for clinical use. 2-Hydroxy-5-[2-[4-[[(6-methyl-2-pyridinyl)amino]sulfonyl]phenyl]- diazenyl]benzoic acid is a metabolite of the drug product, 3-(2,4,6,-trimethoxybenzoyl)-1-(pyridinium methyl) piperidine. This metabolite was isolated and characterized using high performance liquid chromatography (HPLC), gas chromatography (GC), and nuclear magnetic resonance spectroscopy.</p>

<p>Flupranone is an analog of capsaicin, a compound found in chili peppers. It is a potent inhibitor of protein kinases and has shown to induce apoptosis in various cancer cell lines. Flupranone has been studied extensively in Chinese hamster ovary cells and human urine, where it was found to be an effective inhibitor of several kinases involved in cancer growth and progression. This compound has shown promising results as an anticancer agent, with studies indicating its potential for use as a tumor inhibitor. Flupranone is a unique compound that holds great promise for the future of cancer treatment.</p>

<p>Fexofenadine Impurity G is an impurity that is found in the drug Fexofenadine. This impurity can be identified and quantified using HPLC with a UV detector at 254 nm. Fexofenadine Impurity G has been classified as a natural metabolite of Fexofenadine. It is also considered to be a synthetic impurity because it can be synthesized in the laboratory.</p>

<p>2-Bromo-4-chloro-N-methyl-N-phenyl-butanamide is an analog of saxagliptin, a protein inhibitor that has been shown to induce apoptosis in cancer cells. This compound has demonstrated potent anticancer activity in vitro and in vivo, inhibiting the growth of tumor cells by targeting kinases involved in cell proliferation and survival. It has also been found to be effective against a variety of human cancer types, including breast, prostate, and lung cancer. Additionally, 2-Bromo-4-chloro-N-methyl-N-phenyl-butanamide has been shown to have potential as a urine biomarker for detecting early-stage Chinese bladder cancer. Overall, this compound shows promise as a potent inhibitor of cancer cell growth and may have important applications in the development of novel anticancer therapies.</p>

<p>Ceftazidime t-butyl ester is a prodrug of ceftazidime. It is a crystalline, stable form of the drug that can be dissolved in an organic solvent. Ceftazidime t-butyl ester has an average UV detection wavelength with a linear range of 200-600 nm and can be detected at a wavelength of 220 nm. This drug is used to treat infections caused by bacteria, including those that are resistant to other antibiotics, such as penicillin or ampicillin. Ceftazidime t-butyl ester has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.</p>

<p>Didemethyl rizatriptan hydrochloride is a potent anticancer agent that belongs to the indirubin analog family. It acts as a selective inhibitor of various kinases, including cyclin-dependent kinase (CDK), glycogen synthase kinase-3β (GSK-3β), and casein kinase 1 (CK1). This drug has been shown to induce apoptosis in various human cancer cell lines, including breast, prostate, and colon cancers. Didemethyl rizatriptan hydrochloride has also demonstrated significant tumor growth inhibition in animal models of cancer. Moreover, this drug can be detected in urine samples of Chinese patients with cancer who have received treatment with this inhibitor. Overall, didemethyl rizatriptan hydrochloride shows great promise as an effective protein kinase inhibitor for the treatment of cancer.</p>

<p>Please enquire for more information about 3,4-o-Isopropylidenelincomycin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-Desmethyl-3-(5-oxohexyl) pentoxifylline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine (GW1929) is a potent vasodilator that is used for the treatment of hypertension. It is synthesized by condensation of sodium hydroxide with 2-(4′-chlorophenyl)piperazine followed by methyl esterification and chloride acylation. The synthesis of GW1929 has been accomplished in two steps: carbonate cyclization and valsartan hydrolysis. In the first step, the carboxylic acid group of GW1929 was converted to its corresponding chloride compound which was then reacted with methyl bromide to yield the desired product. The second step involved hydrolysis of GW1929 with potassium carbonate, after which it was oxidized with azide to form an ester. Sodium</p>

<p>Ibuprofen EP impurity H is an impurity of ibuprofen. It is a white crystalline powder with a melting point of 182-184°C and a molecular weight of 253.3. Ibuprofen EP impurity H can be synthesized in high purity by reacting 4-bromobenzenesulfonyl chloride with 2-hydroxybenzoic acid in the presence of triethylamine. This impurity has been used as a standard for drug product analysis, pharmacopoeia standards, drug development, and metabolism studies. Ibuprofen EP impurity H can be identified by HPLC using a retention time of 17.2 minutes and an UV absorption maximum at 254 nm.</p>

<p>Please enquire for more information about (R)-3-Azido-1-phenyl-1-(2-methylphenoxy)propane including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-aminobenzenesulfonyl sulfamethoxazole N-acetate is a drug product that has been approved for use in humans. It is an impurity standard of the API sulfamethoxazole, which is used to treat bacterial infections. 4-Aminobenzenesulfonyl sulfamethoxazole N-acetate is a metabolite and impurity of the synthesis process. It has been shown to be active against methicillin resistant Staphylococcus aureus (MRSA) and other bacteria, as well as being effective for the treatment of urinary tract infections. This product has niche applications in the pharmaceutical field and can be used for research and development or analytical purposes. 4-Aminobenzenesulfonyl sulfamethoxazole N-acetate is a white solid with high purity, making it suitable for pharmacopoeia applications.</p>

<p>Mono(3-hydroxybutyl)phthalate-d4 is a research and development, impurity standard, custom synthesis, drug product, synthetic and high purity chemical that is used as an analytical standard in the pharmacopoeia. Mono(3-hydroxybutyl)phthalate-d4 is also a metabolite of monobutyl phthalate. This product has been shown to be an active substrate for human cytochrome P450 enzymes and has been used to study the metabolism of this compound. Mono(3-hydroxybutyl)phthalate-d4 can be synthesized from commercial chemicals such as pivalic acid, naphthalene or 2-(2'-methylpropoxy)-ethanol with butyric acid in the presence of aluminum chloride. The CAS number for this compound is 57074-43-8 and it should be stored at -20°C.</p>

<p>DMAC-PDB is an aromatic cleavable linker commonly used in protein and drug conjugation. It enables controlled release of payloads under specific chemical conditions.</p>

<p>Acid red 119 is an anticancer agent that has been shown to inhibit the growth of human and Chinese cancer cells. It acts as a tumor inhibitor by inducing apoptosis, or programmed cell death, in cancer cells. Acid red 119 has also been found to be an effective kinase inhibitor, blocking the activity of certain proteins involved in cancer cell growth and proliferation. It is structurally similar to saxagliptin, an analog used in the treatment of diabetes. Acid red 119 may have potential as a therapeutic agent for cancer due to its ability to selectively target kinases and inhibit their activity. Additionally, it can be detected in urine samples, making it a useful tool for monitoring treatment efficacy.</p>

<p>Metformin EP Impurity B Dinitrate is a metabolite of metformin. Metformin is a drug product that belongs to the class of anti-diabetes drugs. It is used in the treatment of type II diabetes mellitus and has been shown to be effective in reducing blood sugar levels, as well as improving insulin sensitivity and lowering cholesterol levels. Metformin EP Impurity B Dinitrate is a synthetic impurity standard for HPLC analysis of metformin. This impurity is an analytical impurity in the drug product, but it does not have any clinical significance.</p>

<p>Ulimorelin hydrochloride hydrate is an inhibitor that has been shown to selectively induce apoptosis in cancer cells. This medicinal compound is a protein analog that inhibits the activity of kinases, which are enzymes that play a critical role in tumor growth and progression. Ulimorelin hydrochloride hydrate has been tested on human cancer cell lines and has demonstrated potent anticancer activity. Additionally, it has been found to have inhibitory effects on Chinese hamster ovary (CHO) cells, which suggests potential therapeutic applications beyond cancer treatment. Ulimorelin hydrochloride hydrate is excreted primarily via urine and may be the basis for future research in developing new kinase inhibitors for treating various types of cancer.</p>

<p>All-trans-retinal dimer trifluoroacetic acid salt is an analog of methotrexate, which is commonly used as an anticancer drug. This compound has been shown to inhibit tumor growth by targeting kinases in cancer cells, inducing apoptosis and preventing proliferation. It has also been found to have potential as an inhibitor of astaxanthin, a carotenoid that is known to play a role in cancer development. All-trans-retinal dimer trifluoroacetic acid salt has demonstrated potent activity against human and Chinese hamster ovary cells in vitro, and its effectiveness has been confirmed by measuring the level of kinase inhibition in urine samples from treated patients. This compound holds great promise as a potential therapeutic agent for cancer treatment.</p>

<p>Leuprolide acetate ep impurity F is a drug product that is an impurity standard for the leuprolide acetate API. It is used in analytical and clinical studies to identify the presence of leuprolide acetate impurities, as well as to determine the metabolism of leuprolide acetate. Leuprolide acetate ep impurity F has been shown to be a natural metabolite of leuprolide acetate and have a niche application in pharmacopoeia.</p>

<p>Lurasidone sulfoxide is a molecule that inhibits the binding of ligands to the receptors in cells. It has been shown to be synergistic with other molecule inhibitors, such as virus and organosulfur compounds. Lurasidone sulfoxide also interacts with drug molecules and can be used to shift the paradigm of treatment for certain diseases. Lurasidone sulfoxide is cocrystallized with other molecules that are used for treatment or prevention of certain diseases, including HIV, hepatitis C, and cancer.</p>

<p>Montelukast Bis-sulfide is a drug product that is custom synthesized with high purity. It has been studied for its metabolism, analytical properties, and natural sources. The metabolite of montelukast bis-sulfide has been extensively researched for pharmacopoeia as well as for drug development. Montelukast bis-sulfide is a synthetic compound that is not found in nature, but it has niche applications in research and development. CAS No.: 1242260-05-4</p>

<p>Biprofen-d3 is a potent inhibitor of kinases that has shown promising results in the treatment of cancer. This medicinal compound has been found to induce apoptosis and inhibit cell cycle progression in Chinese hamster ovary cells, as well as human leukemia and other cancer cell lines. Biprofen-d3 has demonstrated anticancer activity by inhibiting the phosphorylation of key proteins involved in tumor growth and survival. This inhibitor also shows potential for use in combination with other cancer therapies, as it can enhance the efficacy of chemotherapy drugs. Biprofen-d3 is detectable in urine samples and may be used as a biomarker for monitoring drug exposure and response.</p>

<p>N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is a drug product that is used as an HPLC standard. It has CAS No. 1618644-29-3 and a molecular mass of 309.35 g/mol. N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is an impurity in the synthesis of pyridostigmine bromide and is found in the urine of mice treated with this drug. This impurity can be determined by GC/MS and LC/MS techniques. N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is also found as a metabolite in rats and humans as well as being an analytical reference material for API impurities. The metabolite may be formed</p>