APIs for research and impurities

3,3'-Bisdemethylpinoresinol is a phenylpropanoid that has been shown to have antioxidant properties. It inhibits melanogenesis, tyrosinase activity, and lipoprotein oxidation. 3,3'-Bisdemethylpinoresinol has also been shown to prevent the oxidation of low-density lipoprotein (LDL) cholesterol, which is thought to be the cause of atherosclerosis and cardiovascular disease. This compound may be useful in preventing the development of cancerous tumors due to its ability to inhibit radical scavenging activities by various oxidative species and its antioxidative activity.

1-Cyclopropyl-7-8-difluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester is a research and development impurity standard. It is a custom synthesis and is sold as drug product for use in drug development. 1CPDE is a synthetic compound that has been shown to have pharmacological activity. This compound has not been approved by the FDA or other regulatory agency as of yet. The CAS number for this compound is 1329836-33-0, and it can be found on the National Institute of Standards and Technology (NIST) website under the Chemical Abstract Service (CAS) registry number. 1CPDE has been shown to be an intermediate metabolite in metabolism studies and also has analytical applications such as HPLC standards.

3-(Benzyloxy)-5-nitrobenzoic acid is a benzimidazole derivative that is synthesized in three steps. It can be formed by reacting potassium chloride, formic acid and 3-hydroxy-5-nitrobenzoic acid. The reaction yields are dependent on the concentration of the reactants. The isomeric mixture can be separated by distillation into two fractions; one fraction contains the desired product and the other fraction contains the undesired product. This compound has been shown to have antibacterial activity against both Gram-positive and Gram-negative bacteria, as well as antifungal activity against Candida albicans. 3-(Benzyloxy)-5-nitrobenzoic acid binds to ribosomes of bacteria, inhibiting protein synthesis by preventing peptide bond formation between amino acids. This compound also reacts with sulfate ion to produce sulfate ester, which inhibits bacterial growth by disrupting membrane integrity.

Please enquire for more information about Benserazide EP Impurity B hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-Methyllidocaine iodide is a drug that is used to treat cardiac arrhythmias. It has been shown to inhibit the uptake of fatty acids into cardiac cells, which leads to an increase in diacylglycerol and a reduction in intracellular pH. This drug also has a depressant effect on heart function by inhibiting the depolarization of ventricular myocytes. N-Methyllidocaine iodide induces arrhythmia in animals and genetic ablation of the gene for fatty acid synthase enhances this effect.

Please enquire for more information about 1-(4-Methyl-2,5-dioxoimidazolidin-4-yl)urea including the price, delivery time and more detailed product information at the technical inquiry form on this page

Ai Product Descriptions 50 Creative

Entecavir (1R,3R,4S) diastereomer is a synthetic compound and is an analytical standard for HPLC. This product is an impurity of the drug Entecavir. The impurity is characterized by a retention time of 17.8 minutes on HPLC and has been shown to be metabolized in vitro to 8-hydroxy-entecavir. The purity of this product is 98% with a CAS number of 1367369-78-5.

Apitoxin is a natural toxin found in the venom of honeybees. Studies have shown that it has potential anti-cancer properties due to its ability to induce apoptosis, or programmed cell death, in human cancer cells. Additionally, apitoxin contains kinases that can inhibit tumor growth and glycerol analogs that have demonstrated anticancer activity in Chinese hamster ovary cells. Indirubin, a compound found in apitoxin, has been identified as a potent inhibitor of kinases involved in cancer cell proliferation. Apitoxin may also be useful as a urinary biomarker for detecting prostate cancer. Overall, the unique properties of apitoxin make it an intriguing candidate for further research into potential cancer treatments.

Desmethylnortriptyline is a tricyclic antidepressant drug that has been shown to have anti-inflammatory properties. It inhibits the production of inflammatory cytokines in the intestine, which may be due to its effect on the induction of apoptosis by inhibiting protein synthesis. Desmethylnortriptyline also has a beneficial effect on bowel diseases, such as colitis and ileitis. This drug inhibits the uptake of serotonin in rat brains and can lead to decreased levels of serotonin in the brain and spinal cord, which may be responsible for its clinical response. Desmethylnortriptyline is metabolized by demethylation and deamination. It undergoes oxidative deamination by cytochrome P450 enzymes found in human liver microsomes and isolated heart tissue, generating an inactive product. The drug also undergoes oxidation by uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) to form an active metabolite.

Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the production of prostaglandins, which are produced by inflammatory cells in response to tissue injury. It is used to treat pain and inflammation. Aceclofenac is absorbed quickly from the gastrointestinal tract and has a high bioavailability. The maximum plasma concentration is reached within 1 hour after oral administration. Aceclofenac has a short half-life of about 2 hours. This drug binds to fatty acids and hepatoprotective substances, such as polymers, pyruvic transaminase, acetate extract, and humans. It also inhibits the transcription of cyclooxygenase-2 (COX-2), which produces prostaglandins that are involved in various aspects of inflammation.

This product is a synthetic impurity of Allopurinol. It is a cyclization reaction product of dimethylhydrazine and allopurinol in the presence of an organic solvent such as DMF.

Captopril EP Impurity N is a synthetic impurity found in Captopril EP, which is used as a drug product for the treatment of hypertension. The impurity standard for Captopril EP Impurity N is available on request.

D-Ribose-1-D is a medicinal compound that has been shown to have anticancer properties. It is a kinase inhibitor that prevents the activation of proteins involved in cancer cell growth and division. Studies have shown that D-Ribose-1-D induces apoptosis, or programmed cell death, in leukemia cells. It also inhibits the cell cycle, preventing cancer cells from dividing and growing. D-Ribose-1-D has potential as an effective treatment for human cancers and may be useful in combination with other inhibitors to enhance its anticancer effects. This compound can be found naturally in Chinese herbs and is excreted in urine after consumption.

Lurasidone sulfoxide is a molecule that inhibits the binding of ligands to the receptors in cells. It has been shown to be synergistic with other molecule inhibitors, such as virus and organosulfur compounds. Lurasidone sulfoxide also interacts with drug molecules and can be used to shift the paradigm of treatment for certain diseases. Lurasidone sulfoxide is cocrystallized with other molecules that are used for treatment or prevention of certain diseases, including HIV, hepatitis C, and cancer.

Cinacalcet is a drug product that is used for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. It is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. Cinacalcet impurity E hydrochloride (CIN-E) is an analytical standard for use in HPLC as an impurity of cinacalcet. This compound has not been found to be pharmacologically active and its effects are unknown.

Tirofiban impurity 8 is an analytical standard for HPLC. It is a research-grade, high purity, impurity standard for the drug product. Tirofiban impurity 8 is a metabolite of tirofiban that has been shown to be pharmacologically active in animal models and in vitro. Tirofiban impurity 8 has a natural or synthetic origin and its CAS number is 2250244-25-6.

DRI-c21045 is an analog of a medicinal compound that has been shown to inhibit the activity of a specific protein kinase involved in cell cycle regulation and tumor growth. This inhibitor has been demonstrated to induce apoptosis in cancer cells, making it a promising candidate for anticancer therapy. DRI-c21045 has been tested in both Chinese and human cancer cell lines and has shown potent activity against various types of tumors. Additionally, this compound has been detected in urine samples from patients with cancer, suggesting that it may have potential as a diagnostic marker for certain types of cancer. Overall, DRI-c21045 shows great promise as a potential anticancer agent with significant therapeutic potential.

3-(3-Trifluoromethylphenyl)propionaldehyde diethylacetal is a synthetic compound that belongs to the class of drug products. It is used for research and development, as well as for developing analytical standards for HPLC. This product has been shown to be metabolized in the rat liver by hydrolysis of the acetal group and oxidation of the alcohol.

Acyclovir Impurity K is a drug product that is used as an analytical reference standard for metabolism studies. Acyclovir Impurity K is a natural product and an impurity of acyclovir, which has CAS No. 1797131-64-6. The chemical name of this drug is 3-hydroxy-2,5,6,7-tetrahydro-1H-[1]benzopyran-2,4(3H)-dione. It can be synthesized in the laboratory by custom synthesis or it can be obtained from a commercial supplier as an impurity standard. This product is used to help with drug development and research and development in the pharmaceutical industry. It can also be used as a high purity HPLC standard for pharmacopoeia testing purposes.

4-Hydroxy azithromycin is an impurity of Azithromycin that is a metabolite of the drug. 4-Hydroxy azithromycin is a synthetic product, which has been synthesized for use as an analytical standard for HPLC and LC-MS/MS. It has also been used as a pharmacopoeia standard for testing antibiotic purity and quality. Metabolism studies have shown that 4-hydroxy azithromycin is not absorbed from the gastrointestinal tract, but is found in the urine and feces.

Amoxicillin EP Impurity H is a potassium clavulanate that is found in Amoxicillin EP. It has bactericidal activity against gram-negative bacteria and can be used to treat infections caused by these bacteria. Amoxicillin EP Impurity H is resistant to many antibiotics, including penicillins, cephalosporins, erythromycin, and tetracyclines. This impurity can be detected using an elemental analysis of the sample or by liquid chromatography with a detection limit of 100 ppm.

2-Demethoxy-4-methoxy urapidil is a drug product that is used in the development of new drugs. It is a synthetic compound that is metabolized to form its natural metabolite, 2-demethoxyurapidil. This impurity standard has been shown to have anti-inflammatory effects and can be used as an API impurity for pharmacopoeia. 2DMO4MU has been shown to be useful in the study of metabolism and has been found to inhibit prostaglandin synthesis.