APIs for research and impurities
Subcategories of "APIs for research and impurities"
- Aminoacids and derivatives(12,331 products)
- Anthraquinones and derivatives(404 products)
- Benzimidazole and Imidazole Derivatives(10,435 products)
- Benzodiazepine Derivatives(333 products)
- Carbohydrates and glycoconjugates(5,050 products)
- Esters and Derivatives(42,250 products)
- Fatty Acids and Lypidic Derivatives(32,404 products)
- Flavonoids and Polyphenols(17,080 products)
- Free Radicals and Oxidant/Reducing Agents(212 products)
- Ketones and derivatives(2,400 products)
- Natural and semi-synthetic antibiotics(6,373 products)
- Nitriles and Cyano Derivatives(3,068 products)
- Nitrosamines and Derivatives(55 products)
- Nucleosides and Nucleotides(3,470 products)
- Organic Phosphates and Phosphonates(1,199 products)
- Organic Sulphonates and Sulphates(10,430 products)
- Organometallics(4,421 products)
- Others(6,297 products)
- Peptides and Proteins(3,143 products)
- Polymers and Derivatives(100 products)
- Purines and Pyrimidine Derivatives(8,934 products)
- Quinazoline and Quinoline Derivatives(65,945 products)
- Quinones and Derivatives(24,357 products)
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)(80,718 products)
- Steroids and Derivatives(4,946 products)
- Sulfonamides and Derivatives(2,587 products)
- Terpenoids and Derivatives(3,843 products)
- Thiazolidinediones and Thiopyrans(2,753 products)
- β-Adrenergic Compounds(230 products)
Found 58070 products of "APIs for research and impurities"
4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
CAS:This is a white crystalline compound that has been shown to be effective against glutamic acid-sensitive L-amino acid decarboxylase. It is used as an intermediate in the synthesis of other pharmaceuticals.
Formula:C10H10N2O4SPurity:Min. 95%Molecular weight:254.26 g/molRef: 3D-IH21390
Discontinued productPreterramide C
CAS:Preterramide C is a drug that belongs to the class of drugs known as aminopyridines. It is a metabolite of preterramide A and has been used as an analytical reference standard for HPLC. This product is available in the form of a pure white crystalline powder with a purity greater than 98%. It has been shown to be an impurity in drug products and can be used as an impurity standard, as well as being synthesized by natural or synthetic means.
Formula:C24H23N3O7Purity:Min. 95%Molecular weight:465.50 g/molRef: 3D-GDA46977
Discontinued productAbt-639 hydrochloride
CAS:Abt-639 hydrochloride is a drug product that is used as a research and development standard. It is a synthetic drug that has not been approved for any therapeutic use. Abt-639 hydrochloride is metabolized to yield an active metabolite, which has been identified in animal studies. The drug product contains an impurity standard of the natural metabolite, which can be used for pharmacopoeia and analytical purposes.
Formula:C20H21Cl2F2N3O3SPurity:Min. 95%Molecular weight:492.4 g/molRef: 3D-KZB56031
Discontinued product(1R,2R)-1-(M-Hydroxyphenyl)-2-amino-1-propanol
CAS:Controlled ProductPlease enquire for more information about (1R,2R)-1-(M-Hydroxyphenyl)-2-amino-1-propanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C9H13NO2Purity:Min. 95%Molecular weight:167.2 g/molRef: 3D-WAA48043
Discontinued productPhenothiazine S,S-dioxide
CAS:Phenothiazine S,S-dioxide is a fluorescent anion that can be used as a buffer. It has an absorption maximum at 514 nm in the visible region and a fluorescence emission maximum at 592 nm. Phenothiazine S,S-doxide blocks the emission of light from phosphor by absorbing the light and reemitting it at a longer wavelength. The luminescence intensity increases with increasing concentration of phenothiazine S,S-dioxide. This compound has been used to develop devices that detect anions in drinking water such as chloride ion. Phenothiazines are also known to have anti-inflammatory effects due to their ability to inhibit prostaglandin synthesis.
Formula:C12H9NO2SPurity:Min. 95%Molecular weight:231.27 g/molRef: 3D-BAA20966
Discontinued productMethyl mycophenolate impurity E
CAS:Methyl mycophenolate impurity E is a reactive, propargylamine-containing, monosodium salt with immunosuppressive properties. It is used in the treatment of cancer by inhibiting the production of white blood cells, which are needed to fight infection. Methyl mycophenolate impurity E has shown antitumor activity and can be used for the treatment of some types of cancer. It is metabolized in vivo to methyl mycophenolate and inhibits protein synthesis by alkylating DNA.
Formula:C18H22O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:334.36 g/molRef: 3D-IM25526
Discontinued productBendamustine isopropyl ester
CAS:Bendamustine isopropyl ester is a synthetic, high purity drug product. It is an impurity standard for the manufacture of Bendamustine hydrochloride, a drug product that is used in cancer chemotherapy. Bendamustine isopropyl ester has been shown to inhibit the metabolism of bendamustine hydrochloride and may be useful as a pharmacokinetic marker in clinical trials. Bendamustine isopropyl ester metabolizes into bendamustine hydroxypyridinium salt, which has been shown to have anti-inflammatory properties.
Formula:C19H27Cl2N3O2Purity:Min. 95%Molecular weight:400.30 g/molRef: 3D-NCC02025
Discontinued productBenz[A]anthracene-7-chloromethane-13C
CAS:Please enquire for more information about Benz[A]anthracene-7-chloromethane-13C including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C19H13ClPurity:Min. 95%Molecular weight:277.7 g/molRef: 3D-RFC05460
Discontinued productN-Methyl metribuzin
CAS:N-Methyl metribuzin is a drug product that belongs to the class of organic compounds known as phenylureas. It is a natural substance, which can be found in plants such as dandelion and rhubarb. Metribuzin has been shown to have pharmacological effects on the human body, including antimetabolite activity, anticancer activity, and anti-inflammatory activities. Metribuzin is metabolized by cytochrome P450 enzymes to form metabolites that are excreted in urine or bile. The metabolites are also active substances and may contribute to the pharmacological effects of metribuzin. Metribuzin can be synthesized from 2-chloro-5-(trifluoromethyl)benzoyl chloride and 3-methylisoxazole.
Metribuzin is used as an analytical standard for HPLC analysis because it has a high purity level and analytical quality. It is also used inFormula:C9H16N4OSPurity:Min. 95%Color and Shape:PowderMolecular weight:228.32 g/molRef: 3D-GCA74245
Discontinued product2-(Acetylamino)-4-amino-2,4,6-trideoxy-α-D-galactopyranose
CAS:Please enquire for more information about 2-(Acetylamino)-4-amino-2,4,6-trideoxy-α-D-galactopyranose including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C8H16N2O4Purity:Min. 95%Molecular weight:204.22 g/molRef: 3D-UQC43429
Discontinued productLinezolid N-oxide
CAS:Please enquire for more information about Linezolid N-oxide including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C16H20FN3O5Purity:Min. 95%Molecular weight:353.35 g/molRef: 3D-IL184105
Discontinued product1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine
CAS:1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine is a synthetic drug product. It is used as an analytical standard to help elucidate the metabolic pathway of drugs and their metabolites. This compound has been shown to be metabolized by various enzymes including CYP450, glutathione reductase, and esterases. It can also be synthesized from 1,4-dihydropyridine and 2-furancarboxaldehyde. The physical properties of 1,4-bis[(tetrahydro-2-furanyl)carbonyl]-piperazine are: white powder; mp 178°C; IR max 1710 cm−1 (CO); UV max 221 nm (EtOH). The impurities in this product are: 1-(2H)-Quinolinone (CAS No. 2467-94-1) which may have a maximum concentration
Formula:C14H22N2O4Purity:Min. 95%Molecular weight:282.34 g/mol1,1-Dimethylethyl (3S,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6- heptenoate
CAS:Please enquire for more information about 1,1-Dimethylethyl (3S,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6- heptenoate including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C26H36FN3O6SPurity:Min. 95%Molecular weight:537.65 g/mol5-O-Desethyl amlodipine
CAS:5-O-Desethyl amlodipine is a metabolite of amlodipine. It has been used as an analytical reference standard for the determination of amlodipine and its metabolites in human plasma and urine. 5-O-Desethyl amlodipine has been reported to be excreted in human breast milk at a concentration that is about 20% of that found in maternal plasma. The drug product is manufactured by HPLC and is classified as a high purity pharmaceutical drug, which means it is free from extraneous substances such as other drugs, proteins, or bacteria.
Formula:C18H21ClN2O5Purity:Min. 95%Molecular weight:380.82 g/molRef: 3D-ID153422
Discontinued productAmoxicillin EP Impurity L
CAS:Amoxicillin EP Impurity L is an impurity standard for amoxicillin. It is a synthetic compound that is used to ensure the quality of amoxicillin drug products. Amoxicillin EP Impurity L has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. This impurity has also been shown to have anti-inflammatory properties and may be due to its inhibition of prostaglandin synthesis.
Formula:C24H29N5O7S2Purity:Min. 95%Molecular weight:563.65 g/molRef: 3D-IA180686
Discontinued productNorethindrone acetate impurity
CAS:Norethindrone acetate impurity is a drug product that is used in the development and research of drugs. It is an analytical standard for norethindrone acetate, which is an impurity found in the synthesis of this drug. Norethindrone acetate impurity can be synthesized in different ways, such as natural or synthetic routes. It is also available as a custom synthesis or it can be purchased as an impurity standard. This compound's CAS number is 1175129-26-6 and it has a purity level of 99%.
Formula:C22H28O3Purity:Min. 95%Color and Shape:PowderMolecular weight:340.46 g/molBupropion (R)-Isomer
CAS:Controlled ProductBupropion is a racemic mixture of two enantiomers. The (R)-isomer is the more active form and is used for the treatment of major depressive disorder, seasonal affective disorder, and nicotine addiction. Bupropion has been shown to inhibit monoamine oxidase type A in humans and other mammals. This inhibition may be responsible for its antidepressant effects. The drug also has an effect on the liver, which can lead to serious side effects such as seizures or death if not monitored carefully. Bupropion has a high affinity for α1-acid glycoprotein, which plays a role in drug interactions with other drugs that are metabolized by this protein.
Formula:C13H18ClNOPurity:Min. 95%Molecular weight:239.74 g/molTianeptine ethyl ester
CAS:Tianeptine is a drug product that belongs to the group of antidepressants. It is metabolized by cytochrome P450 enzymes in the liver and excreted in urine. Tianeptine ethyl ester is used as an analytical reference standard for the tianeptine content of HPLC samples. The CAS number for tianeptine ethyl ester is 66981-77-9.
Formula:C23H29ClN2O4SPurity:Min. 95%Molecular weight:465.00 g/molRef: 3D-RCA98177
Discontinued productMinocycline EP Impurity H
CAS:Please enquire for more information about Minocycline EP Impurity H including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C23H25N3O7Purity:Min. 95%Molecular weight:455.47 g/mol8-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-octen-4-ol
CAS:Please enquire for more information about 8-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-octen-4-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C14H30O2SiPurity:Min. 95%Molecular weight:258.47 g/molRef: 3D-PNA56366
Discontinued productMch-1 antagonist 1
CAS:Mch-1 antagonist 1 is a drug product that is custom synthesized and is available in high purity. This compound is analytical, and it has been shown to be metabolized in vivo. Metabolism studies have been performed using this compound for the purposes of drug development. CAS No. 1039825-68-7 is the unique identification number for this compound, and it appears on the U.S. Drug Enforcement Administration's list of controlled substances as a natural product. It can be found in the pharmacopoeia as both a synthetic and natural product, with its synthetic form being an impurity standard for HPLC analysis. Mch-1 antagonist 1 has also been studied for its potential use in niche areas such as research and development of drugs or as an analytical standard for HPLC analysis.
Formula:C25H26N4O2Purity:Min. 95%Molecular weight:414.5 g/molRef: 3D-PRB82568
Discontinued productBortezomib impurity 76
CAS:Bortezomib impurity 76 is an analytical reference material that is used in the development and production of pharmaceuticals. It is a high purity, HPLC standard for use as an impurity in the manufacture of bortezomib API. This material is a metabolite of bortezomib and it has been shown to be pharmacologically active. Bortezomib impurity 76 can also be used as an HPLC standard for drug product analysis.
Formula:C21H44BNO2Si2Purity:Min. 95%Color and Shape:PowderMolecular weight:409.56 g/molRef: 3D-IB181070
Discontinued productHaloxyfop-d4
CAS:Haloxyfop-d4 is an analog of the herbicide Haloxyfop that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a key role in cell division and growth. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. Haloxyfop-d4 has been found to be effective against a variety of human cancer cell lines, including those resistant to other anticancer drugs. In addition, it has been shown to inhibit the growth of tumors in animal models. This drug is metabolized in the liver and excreted in urine. It is not known to interact with other drugs such as rifampicin or protein kinase inhibitors.
Formula:C15H11ClF3NO4Purity:Min. 95%Molecular weight:365.72 g/molRef: 3D-CFA89334
Discontinued product(E)-2-Furaldehyde, (2,4-dinitrophenyl)hydrazone
CAS:Please enquire for more information about (E)-2-Furaldehyde, (2,4-dinitrophenyl)hydrazone including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C11H8N4O5Purity:Min. 95%Molecular weight:276.2 g/molRef: 3D-RAA41622
Discontinued product5-Desbromo, 5-chloro brimonidine
CAS:5-Desbromo, 5-chloro brimonidine is a drug product that is used as an analytical standard. It has been shown to be metabolized by CYP3A4 and CYP2D6 enzymes.
Formula:C11H10ClN5Purity:Min. 95%Molecular weight:247.68 g/molRef: 3D-RDA14746
Discontinued product5α,6α-Epoxycholestanol-d7
CAS:Controlled Product5α,6α-Epoxycholestanol-d7 is an impurity of a cholestatic drug product. It can be used as a research and development standard or as an impurity standard in the production of drugs. 5α,6α-Epoxycholestanol-d7 has been characterized by GC/MS and HPLC techniques. This compound is also useful for pharmacopoeia purposes, drug development, and metabolic studies.
Formula:C27H39O2D7Purity:Min. 95%Molecular weight:409.69 g/molRef: 3D-CFA68538
Discontinued productN-Methyl formoterol fumarate
CAS:N-Methyl formoterol fumarate is a drug product for the treatment of asthma and chronic obstructive pulmonary disease. It is a synthetic drug that has been approved by the FDA, but is also a metabolite of terbutaline. Metabolism studies have shown that N-methyl formoterol fumarate is an impurity in Terbutaline sulfate and Terbutaline hydrochloride. This drug is not active against bacteria, but may be used as an analytical standard to measure the purity of other drugs.
Formula:C44H56N4O12Purity:Min. 95%Molecular weight:832.94 g/molRef: 3D-VWC13397
Discontinued productRegadenoson Impurity 28
CAS:Regadenoson Impurity 28 is an analytical standard and research and development impurity. It is a high-purity, synthetic, drug product impurity that can be used as a reference material for HPLC. This drug impurity is also available in a custom synthesis service. Regadenoson Impurity 28 is an API impurity that can be used in the development of drugs. It has been shown to have pharmacopoeia purity standards and niche applications. Regadenoson Impurity 28 is metabolized by cytochrome P450 enzymes to form active metabolites that are not active against the beta-1 adrenergic receptor in rat heart cells, but are active against the alpha 1 adrenergic receptor in rat vascular smooth muscle cells.
Formula:C10H14N6O3Purity:Min. 95%Molecular weight:266.26 g/molCefazedone Impurity 12
CAS:Cefazedone Impurity 12 is a drug product that has been custom synthesized for research and development purposes. The impurity has been shown to have a high purity level, with a CAS number of 184696-69-3. Cefazedone Impurity 12 is an analytical standard and metabolite of Cefazedone. It is also used as a natural drug development standard, which can be used for pharmacopoeia studies or as a metabolite in niche research. This impurity can be synthesized in the laboratory and can be used as an impurity standard for HPLC.
Formula:C8H8N2O3SPurity:Min. 95%Molecular weight:212.23 g/molRef: 3D-FC180714
Discontinued productDioctyl carbonate
CAS:Dioctyl carbonate is a pharmaceutical preparation used to treat skin conditions. It is a fatty acid ester of carbonic and carbonyl groups in which the two esters are in the same molecule. Dioctyl carbonate is a reaction product obtained by reacting an inorganic acid, such as hydrochloric acid or sulfuric acid, with an alcohol containing two hydroxyl groups and one double bond. This reaction may be facilitated by heating. The film-forming polymer may be polyvinylpyrrolidone, polyvinyl alcohol, or polyacrylic acid. Dioctyl carbonate has been shown to stimulate colony-stimulating factor production and inhibit the proliferation of human epidermal keratinocytes.
Formula:C17H34O3Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:286.4 g/mol1-Phenyl-1,2,3,4-tetrahydro-isoquinoline
CAS:1-Phenyl-1,2,3,4-tetrahydro-isoquinoline is a synthetic compound which has been used as a lead compound for the development of drugs with dopamine β-hydroxylase inhibitory activity. In vitro studies have shown that 1-phenyl-1,2,3,4-tetrahydro-isoquinoline inhibits human serum dopamine β-hydroxylase and can be used to study the possible role of this enzyme in Parkinson's disease. This drug is racemized in the body and has been found to be effective against Parkinson's disease in rats. It is also an enantiomer that has industrial applications for the production of polyurethane foam insulation coatings.
Formula:C15H15NPurity:Min. 95%Color and Shape:PowderMolecular weight:209.29 g/molRef: 3D-IP14816
Discontinued product2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid
CAS:2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid (KZPBA) is a zoonotic antibiotic that has been shown to be active against agalactiae. It is a prodrug, which is metabolized to the active form, KZPBA, in humans and other mammals. The mechanism of action of KZPBA is not yet known; however, it has been hypothesized that its activity may be due to inhibition of DNA gyrase and topoisomerase IV. This drug has also been shown to have an effect on mastitis in dairy cows.Formula:C19H29O6PPurity:Min. 95%Molecular weight:384.4 g/molRef: 3D-IM27637
Discontinued product6-o-Desmethyl moxonidine
CAS:6-O-Desmethyl moxonidine is a drug product that is a metabolite of the parent compound, moxonidine. It has been shown to be an impurity in the API (active pharmaceutical ingredient) and is used as an analytical standard for HPLC. 6-O-Desmethyl moxonidine is synthetically prepared and can be found in natural sources, such as plants or animals. The metabolism studies indicate that the substance is excreted unchanged in urine following oral administration and undergoes extensive hydrolysis in liver microsomes to yield 4-hydroxy-3-(3-hydroxymethylpiperidinopropyl) piperidine, which is then oxidized to 3-(4-hydroxypiperidinopropyl)-1H-1,2,4-triazole. This product may cause skin irritation.
Formula:C8H10ClN5OPurity:Min. 95%Molecular weight:227.65 g/molRef: 3D-CPA45733
Discontinued producto-Desphenyl sofosbuvir
CAS:o-Desphenyl sofosbuvir is a drug product that has been custom synthesized for research purposes. It is made of pure natural ingredients and does not contain any impurities. o-Desphenyl sofosbuvir is a metabolite from the synthesis of sofosbuvir, a drug used to treat hepatitis C. It can be used in pharmaceutical research and development as an analytical standard for HPLC.
Formula:C16H25FN3O9PPurity:Min. 95%Molecular weight:453.36 g/molPteroic acid, min95%
CAS:Pteroic acid is a naturally occurring substance found in plants and animals. It has inhibitory activities against enzymes such as butyrate kinase, acetyl-CoA synthetase, and glutamate dehydrogenase. Pteroic acid is used to synthesize quinoxalines, which are used for the treatment of cancer. Pteroic acid also inhibits cell growth by inhibiting protein synthesis. This is done by conjugating with amino acids and inhibiting their uptake into the ribosome. The inhibition of glutamate dehydrogenase may be due to its ability to reduce levels of glutathione, which is an inhibitor of this enzyme.
Formula:C14H12N6O3Purity:Min. 95%Color and Shape:Slightly Yellow PowderMolecular weight:312.28 g/mol6-Bromo-6-dehydro-17a-acetoxy progesterone
CAS:Controlled Product6-Bromo-6-dehydro-17a-acetoxy progesterone is a drug product that can be used as an HPLC standard or as a synthetic intermediate. It is a natural metabolite of progesterone, which is also a natural hormone. 6-Bromo-6-dehydro-17a-acetoxy progesterone has been shown to have antihypertensive and vasodilatory activities, which may be due to its ability to bind to beta adrenergic receptors in the vascular system. This metabolite of progesterone has also been shown to inhibit the metabolism of testosterone by inhibiting the enzymes 17beta hydroxysteroid dehydrogenase and 5alpha reductase, which lead to an increase in testosterone levels in blood plasma.Formula:C23H29BrO4Purity:Min. 95%Molecular weight:449.38 g/mol(+/-)N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride
CAS:N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride is a synthetic drug product that has been shown to be metabolized in humans. It is an impurity standard for HPLC and analytical methods. This compound is used as a research chemical in the development of drugs, and is also used as a pharmacopoeia reference standard.Formula:C17H18F3NO·HClPurity:Min. 95%Molecular weight:345.79 g/molRef: 3D-IM58072
Discontinued productcis-Tadalafil
CAS:Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.
Formula:C22H19N3O4Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:389.4 g/molTofacitinib dihydro impurity
CAS:Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.
Formula:C16H22N6OPurity:Min. 95%Molecular weight:314.39 g/molSacubitril Impurity 2
CAS:Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.
Formula:C24H27NO4Purity:Min. 95%Molecular weight:393.48 g/mol(4-Chlorophenyl)diphenylmethanol
CAS:Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C19H15ClOPurity:Min. 95%Molecular weight:294.8 g/molRef: 3D-GAA92289
Discontinued productSimvastatin acid
CAS:Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin
Formula:C25H40O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:436.58 g/molRef: 3D-IS63828
Discontinued productIvermectin impurity I
CAS:Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.
Formula:C48H74O14Purity:Min. 95%Color and Shape:PowderMolecular weight:875.09 g/molRef: 3D-II167729
Discontinued productRocuronium Bromide EP Impurity F Bromide
CAS:Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.Formula:C34H55N2O4·BrPurity:Min. 95%Molecular weight:635.72 g/molN-Benzyl albuterol
CAS:N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.
Formula:C20H27NO3Purity:Min. 95%Molecular weight:329.4 g/molPiperacilloic acid
CAS:Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.
Formula:C23H29N5O8SPurity:(Elemental Analysis) Min. 90 Area-%Color and Shape:PowderMolecular weight:535.57 g/molEmpagliflozin S-furanose
CAS:Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.
Formula:C23H27ClO7Purity:Min. 95%Color and Shape:PowderMolecular weight:450.91 g/molRef: 3D-IE181148
Discontinued productAcarbose Impurity E
CAS:Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.
Purity:Min. 95%Desfluoro ezetimibe
CAS:Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.
Formula:C24H22FNO3Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:391.43 g/molDicyclopropylamine hydrochloride
CAS:Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D
Formula:C6H11N•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:133.62 g/molRef: 3D-FD141573
Discontinued productPramipexole EP Impurity C
CAS:Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Formula:C20H32N6S2Purity:Min. 95%N-Desacetyl thiocolchicoside
CAS:N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.
Formula:C25H31NO9SPurity:Min. 95%Molecular weight:521.58 g/molRef: 3D-CHA99181
Discontinued productRoflumilast Impurity A
CAS:Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.
Formula:C16H14Cl2N2O3Purity:Min. 95%Molecular weight:353.2 g/mol(3S,4R)-Tofacitinib
CAS:(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.
Formula:C16H20N6OPurity:Min. 95%Molecular weight:312.37 g/molOxacyclohexane open ring tacrolimus
CAS:Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C44H71NO13Purity:Min. 95%Molecular weight:822.04 g/molCiprofloxacin ep impurity C
CAS:Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.
Formula:C15H16FN3O3Purity:Min. 95%Molecular weight:305.30 g/molRef: 3D-DEA22212
Discontinued product2-(2-Amino-5-bromobenzoyl)pyridine
CAS:2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval
Formula:C12H9BrN2OPurity:Min. 95%Molecular weight:277.12 g/mol3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride
CAS:3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.
Formula:C19H25ClN2O2Purity:Min. 95%Molecular weight:348.9 g/molRef: 3D-WMD18565
Discontinued product(S)-Rabeprazole sodium
CAS:(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.
Formula:C18H21N3O3S•NaPurity:Min. 95%Molecular weight:382.43 g/molRef: 3D-IR183125
Discontinued productN-Hydroxymethyl Sumatriptan
CAS:N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).
Formula:C15H23N3O3SPurity:Min. 95%Molecular weight:325.43 g/molTerbinafine dihydrochloride
CAS:Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.
Formula:C36H40N2Purity:Min. 95%Molecular weight:500.7 g/molRef: 3D-JMB36523
Discontinued productN-Nitroso dorzolamide
N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.
Formula:C10H15N3O5S3Purity:Min. 95%Color and Shape:PowderMolecular weight:353.44 g/molLinagliptin impurity G
CAS:Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.
Formula:C25H28N8O2Purity:Min. 95%Color and Shape:PowderMolecular weight:472.54 g/molTriethylene glycol flufenamate
CAS:Etofenamate impurity
Formula:C20H22F3NO5Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:413.39 g/molRef: 3D-IT58094
Discontinued productChlorthalidone impurity E
CAS:Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>
Formula:C14H11ClN2O3SPurity:Min. 95%Molecular weight:322.77 g/molRef: 3D-IC76330
Discontinued productD-6-Cyano-6-norlysergic acid methyl ester
CAS:Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C17H15N3O2Purity:Min. 95%Molecular weight:293.32 g/molRef: 3D-FBA33404
Discontinued productGS 441524 triphosphate
CAS:Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.
Formula:C12H12N5O13P3·4NaPurity:(31P-Nmr) Min. 95 Area-%Color and Shape:White PowderMolecular weight:531.20 g/molRef: 3D-FG167050
Discontinued productAtorvastatin calcium trihydrate EP Impurity G
CAS:Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.
Formula:C34H37FN2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:572.67 g/mol
