APIs for research and impurities

11-(1-Piperazinyl)dibenzo[b,f][1,4]thiazepine hydrochloride is a drug product that is used as an impurity standard in the manufacture of 11-aminoundecanoic acid. It is also used to study the metabolism of this compound. This drug product is not intended for use in humans or animals.

2-Phenylbutyric acid is a product of the oxidation of phenylacetic acid by flavus. 2-Phenylbutyric acid is an inhibitor of contactor reactions that use α1-acid glycoprotein as a chromatographic support. It has been shown to inhibit the reaction mechanism of extractants (e.g., butamirate citrate) with enantiomeric compounds (e.g., creatine). It also inhibits subclinical mastitis in cows and fatty acid synthesis, leading to decreased cholesterol synthesis in humans.

Olsalazine sodium impurity C is a metabolite of olsalazine sodium. It is a natural product that can be custom synthesized for research and development purposes. Olsalazine sodium impurity C has been shown to have pharmacopoeia-grade purity and can be used as an analytical standard or an API impurity in drug products. The CAS number for this substance is 259151-72-9.

Terbutaline Impurity D is a synthetic drug with the CAS number 94109-61-2. This product has been developed as an impurity standard for Terbutaline, which is a drug product that has been approved by the United States Pharmacopoeia (USP). Terbutaline Impurity D can be used to study the metabolism of Terbutaline in animals. It is also used to develop new drugs by chemists and other scientists.

6-Epi pravastatin sodium salt is a synthetic compound with the same molecular formula and chemical structure as the natural product. It has been used in pharmacological studies, drug development, and research. 6-Epi pravastatin sodium salt is a metabolite of pravastatin.

2-Carboxybenzoyl amlodipine is a metabolite of the antihypertensive drug amlodipine. It is a white crystalline solid that is soluble in water. 2-Carboxybenzoyl amlodipine can be used as an impurity standard for HPLC analyses, and as an analytical standard for the determination of amlodipine in human plasma.

Tacrolimus is a macrolide that is used as an immunosuppressive drug. It has been shown to bind to the FK-binding protein, which in turn inhibits calcineurin. This prevents the release of IL-2, TNF-α and other cytokines. The immunosuppressive effects of tacrolimus have been evaluated using analytical methods such as coefficients, affinity, and monitoring techniques such as immunoassays and agglutination. These techniques are used to evaluate the plasma concentration of tacrolimus. Tacrolimus also binds to proteins in the blood samples and can be detected by turbidimetric or electrochemiluminescence immunoassay reagents.

NLRP3i is a molecule that is orally administered and has been shown to have anti-inflammatory effects in the heart. NLRP3i reduces pro-inflammatory cytokines and protects against cardiac dysfunction in mice with chronic kidney disease. It also protects against heart failure caused by ischemia reperfusion. This drug has been shown to be effective as a therapy for cancer, with some patients being resistant to chemotherapy, although it is not yet approved for this use.

Cetirizine is a drug product that is metabolized to cetirizine propanediol ester. This impurity has been identified in the drug and is not expected to cause any adverse effects in humans. Cetirizine propanediol ester can be synthesized and purified through high-purity, analytical, and natural methods. The pharmacopoeia defines cetirizine propanediol ester as a metabolite of cetirizine. It can also be used as an impurity standard for HPLC analysis.

10,11-Dihydroxy-d10 Carbamazepine is a drug product that is used as an analytical reference standard. It is natural and synthetic impurity in the API (active pharmaceutical ingredient) Carbamazepine. The CAS number for 10,11-Dihydroxy-d10 Carbamazepine is 513-81-5. This compound has been synthesized by custom synthesis and is an impurity standard for HPLC analysis of carbamazepine. 10,11-Dihydroxy-d10 Carbamazepine is also a research and development chemical for the drug development industry. It has been classified as a niche chemical due to its high purity and pharmacopoeia grade.

Lenvatinib impurity 10 is a synthetic impurity that is used as an analytical standard in HPLC. It is also a metabolite of lenvatinib and has been found to have anti-inflammatory properties. Lenvatinib impurity 10 is available in high purity and can be custom synthesized to meet the needs of your research or development.

2-Mercaptobenzimidazole is a chemical compound that can be used for the treatment of infectious diseases. It has been shown to have antioxidative properties and inhibit the growth of bacteria. 2-Mercaptobenzimidazole also has an effect on human serum, which may be due to its ability to bind with proteins in serum and form hydrogen bonds. 2-Mercaptobenzimidazole is stable at high temperatures and has been shown as an effective antimicrobial agent against gram positive and gram negative bacteria.

Tirzepatide impurity.

Dapagliflozin Impurity 4 is a research and development impurity standard for the drug Dapagliflozin. Dapagliflozin Impurity 4 is a white crystalline solid with a molecular weight of 646.5 and an empirical formula of C20H22N2O2. It is soluble in water, methanol, ethanol, and acetonitrile. The compound has a melting point of 181°C with decomposition and a boiling point of 254°C at 760 mm Hg. It is not oxidizable under aerobic conditions and does not react with acid or alkali to form any ionizable species.

Naltrexone impurity A is a synthetic, high-purity drug product that is used as an analytical reference standard in the development and manufacture of pharmaceuticals. It is also used as a pharmacopoeia reference standard and to study metabolism. Naltrexone impurity A has been shown to be a major metabolite of naltrexone and can be found in the urine at concentrations of 1-2% following oral administration. This impurity is not active when given orally, but may have activity if injected intravenously or intramuscularly.

Memantine impurity IV is a hydrolysis product of memantine. It appears as a white to off-white powder and has a molecular weight of 198.1 g/mol. Memantine impurity IV is an intermediate in the production of memantine and is therefore not used for any other purpose. The compound contains hydroxy groups, hydroxy, alcohols, and bridgehead groups which are efficient at hydrolyzing to form amino acids.

Olanzapine Ketolactam is a drug product that can be custom synthesized. It has a purity of at least 98% and is identified by its CAS number, 1017241-34-7. The metabolite of Olanzapine ketolactam is olanzapine N-oxide, which can be found in the urine of patients who have taken Olanzapine ketolactam. Metabolism studies have been conducted on this drug product to determine how it may affect the body. This drug product is also used in natural or synthetic drug development, pharmacopoeia, and analytical research.

Dicyclopropylamine is a molecule that has been clinically developed as a drug. It is an inhibitor of the enzyme tyrosinase, which is involved in the production of melanin, and has been shown to have anti-cancer properties. Dicyclopropylamine hydrochloride has been shown to be effective against aliphatic hydrocarbons such as hexane and cyclohexane, as well as aromatic compounds such as benzene and toluene. This drug can also bind to coordination complexes with high kinetic energy, which may be useful for tumor treatment. Dicyclopropylamine hydrochloride can be used for the clinical treatment of human epidermoid carcinoma.

Di-2-thienylmethanone is a pyrazole with an activation energy of about 10.5 kcal/mol. It has been found to be toxic and can cause cell lysis. This molecule has been used in the synthesis of a number of drugs, including thiopental, a barbiturate that is used as an anaesthetic. Di-2-thienylmethanone is also the precursor for the synthesis of fluoroquinolones, which are potent antibacterial agents. The Friedel-Crafts reaction is one way this molecule is synthesized, and it involves the addition of an alkyl halide to an unsaturated double bond. This reaction is named after Charles Friedel and James Crafts who first discovered it in 1877.

Urolithin M5 is a drug product that has undergone custom synthesis, and is high in purity. It has CAS No. 91485-02-8, analytical data, metabolism studies, and drug development. Urolithin M5 is natural, with a metabolite pharmacopoeia and niche. There are impurities in this substance that are of synthetic origin and have an analytical HPLC standard. This substance has been researched and developed for use as an Impurity Standard.

Terbinafine is an antifungal agent that belongs to the family of medicines. It is used to treat fungal infections of the skin, nails and scalp. Terbinafine can also be used to treat other types of fungal infections, such as tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athlete's foot) and tinea capitis (scalp ringworm). Terbinafine dimer impurity dihydrochloride is a by-product of terbinafine hydrochloride that has been shown to have industrial applications as a dispersant or lubricant in industries such as papermaking.

Esomeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease and other conditions where there is too much stomach acid. It is available as a capsule or tablet in doses of 20, 40, and 60 mg. Esomeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium adenosine triphosphate (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cells. Omeprazole is an acidic drug that blocks the H+/K+ ATPase enzyme system. The two drugs have been compared in two-way crossover studies using healthy volunteers who were given omeprazole magnesium for one week followed by esomeprazole sodium for another week. There was no difference in their effect on acid secretion or on heartburn relief. The plasma concentrations of both drugs increased with increasing dose, but there was no significant difference between them in terms of either

Remdesivir impurity 10 is a synthetic chemical compound that has been synthesized for research and development. It is an impurity standard of remdesivir, which is not present in any drug product. The purity of this product is high, and it can be used as a pharmacopoeia or drug development standard. It can also be used as an analytical standard to measure the concentration of metabolites in animal studies or metabolism studies.

Olmesartan medoxomil is a prodrug that is hydrolyzed to olmesartan, its active form. It is a member of the angiotensin II receptor antagonists and it is used for the treatment of hypertension and heart failure. Olmesartan medoxomil reduces the risk of cardiovascular events in patients with resistant hypertension or heart failure. The drug binds to the angiotensin II type 1 receptor, thereby blocking the binding of angiotensin II to this receptor. This prevents activation of downstream signaling pathways, including phospholipase C, protein kinase C, and mitogen-activated protein kinases. Olmesartan medoxomil also blocks the formation of new blood vessels and vascular remodeling in animal models.

Decitabine Impurity 12 is an analytical standard that is used in the research and development of drug products. It is a high purity, HPLC-grade impurity that complies with USP/NF requirements. Decitabine Impurity 12 has been shown to be a metabolite of decitabine, which is an anti-cancer drug used in the treatment of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This impurity has also been shown to have pharmacopoeia value as an impurity standard for drug products.

Tirzepatide Impurity

Bis-[5-[(dimethylamino)methyl]furan-2-yl]methane is a synthetic compound with the CAS number 16864-73-6. It is used in pharmacological studies and drug development. The purity of this material is greater than 99%.

Please enquire for more information about Ceftazidime impurity G including the price, delivery time and more detailed product information at the technical inquiry form on this page

Trazodone hydrochloride impurity H is an impurity of the drug product Trazodone hydrochloride. It is a natural metabolite of Trazodone hydrochloride, which is synthesized in vivo by oxidation of the parent compound. Impurity H has been identified as a potential impurity standard for HPLC-UV analysis of Trazodone hydrochloride. The purity of this compound is 98.3% and it is available on a custom synthesis basis.

α-Methyl-1,3-benzodioxole-5-propanamine (AMEB) is a chemical compound that minimizes the reaction products in industrial reactions. It has been used as an absorption agent and crosslinking agent in bioconjugate chemistry. The hydroxyl group on AMEB can be removed by hydrolysis to yield α-methyl-1,3-benzodioxole, which can then be converted to the amino acid methionine. AMEB has also been shown to have locomotor activity and to increase the synthesis of hyaluronic acid, which is important for maintaining joint health.

Olsalazine sodium impurity D is a natural substance that is present as an impurity in the drug Olsalazine sodium. It is used as an analytical standard for Olsalazine sodium and its metabolites, which are involved in drug development. The purity of this substance can be customized by our research and development team. This product has CAS number 93964-55-7 and is available at a reasonable price.

Isoribavirin is a ribonucleoside monophosphate analog that inhibits viral RNA polymerase. Isoribavirin has been shown to be active against influenza virus, herpes simplex virus, and vesicular stomatitis virus in cell culture. Isoribavirin is stable in an acetonitrile solution in the presence of phosphoric acid at pH 3-4 or in the presence of sulfate ions at pH 9-10. It can be purified by chromatography on a silica gel column using an acetonitrile/water mobile phase gradient. The impurities of isoribavirin are not detectable by liquid chromatography and have no significant effect on its sensitivity. Isoribavirin elutes from the silica gel column with the impurities.

Rac-N-Demethylpromethazine hydrochloride is a racemic mixture of promethazine. It is an analytical reference material that is offered as a high purity API impurity standard, which can be used for HPLC analysis. Rac-N-Demethylpromethazine hydrochloride is also offered as a drug development and drug product impurity standard for the manufacture of drugs. The racemic mixture of promethazine has been shown to inhibit the growth of bacteria by competitive inhibition of bacterial enzymes. Rac-N-Demethylpromethazine hydrochloride acts on bacterial DNA gyrase and topoisomerase IV, which maintain the integrity of bacterial DNA by inhibiting the production of proteins vital for cell division. Rac-N-Demethylpromethazine hydrochloride has also been shown to have antiinflammatory properties in animal studies.

N-(2-Amino-4-thiazolyl)acetyl mirabegron is a research chemical that belongs to the category of drugs. It is custom synthesized and purified through analytical methods. N-(2-Amino-4-thiazolyl)acetyl mirabegron has been studied for its metabolism in vivo, including its pharmacokinetics and pharmacodynamics. This drug product is a metabolite of mirabegron, an agent used for the treatment of overactive bladder syndrome (OAB). The metabolite is also present in urine and plasma samples.

4-(2-Methoxyethyl)phenol is a synthetic compound that is an antihypertensive agent. It is used to reduce high blood pressure, which may be due to its ability to block the action of angiotensin II, a potent vasoconstrictive hormone, by binding with its receptor. 4-(2-Methoxyethyl)phenol has been shown to be more potent than metoprolol succinate and less toxic than hydroxylated compounds such as propranolol in pharmacokinetic studies. In addition, 4-(2-Methoxyethyl)phenol has been found to have a low risk of congestive heart failure. The industrial process for this substance involves the reaction of hydrochloric acid with phenol in the presence of a catalyst such as aluminium chloride or zinc chloride.

Everolimus is an immunosuppressant that belongs to the group of rapamycin analogs. It is a synthetic drug and has been shown to be effective in preventing rejection of transplanted organs, such as kidneys, livers, and hearts. Everolimus O-ethyl impurity is a metabolite of everolimus that can be used as a standard for HPLC analysis. The CAS number for this impurity is 1704711-12-5. Everolimus O-ethyl impurity can also be used as a reference material in metabolism studies.

Trazodone is a psychotropic agent that belongs to the group of antidepressants. Trazodone hydrochloride impurity C is a metabolite of trazodone and can be used as an impurity standard for the drug product in pharmacopoeia. Trazodone hydrochloride impurity C has been found in urine, blood, and saliva after administration of trazodone. It is also found in the plasma of pregnant women who are taking trazodone to treat depression or anxiety during pregnancy.
Trazodone hydrochloride impurity C is synthesized using a custom synthesis with high purity. It has been shown to have a niche market as an analytical reference material for HPLC standards.

N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine is a synthetic, nonstandardized HPLC standard that is used in drug development and metabolism studies. It is not available as a natural product, but can be made synthetically. N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine has the CAS No. 676129-92-3 and impurity standards are available for this compound.

Remdesivir is an antiviral drug. It is an RNA-dependent RNA polymerase inhibitor that has been shown to be effective against a broad range of RNA viruses, including influenza A and B, rhinovirus, respiratory syncytial virus, and parainfluenza virus. Remdesivir impurity 7 (impurity) is a byproduct of the synthesis process of remdesivir. It is a white crystalline solid with a strong chemical odor. This impurity can be synthesized in high purity as well as in custom specifications to meet the needs of pharmaceutical companies developing new drugs.

5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole is an inhibitor of cytochrome P450 2C19. It has been shown to inhibit the activity of this enzyme in a concentration dependent manner and to enhance the activity of omeprazole by inhibiting its metabolism. 5-Methoxy-2-[(4-methoxy, 3,5 dimethylpyridiniumyl)methyl]sulfonyl]-1H benzimidazole is used as a model system for studying drug interactions due to its ability to inhibit cytochrome P450 2C19 and CYP2C19 protein expression. 5 METHOXY - 2 - [[ ( 4 - METHOXY - 3 , 5 - DIMETHYL - 2 - PYRIDINYL ) M

N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine methyl ester is a synthetic compound used as an HPLC standard. It is also used in the development of new drugs to study the metabolism of these drugs and their metabolites. N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine methyl ester can be synthesized from 2-[(2H)-tetrazol-5-yl][1,1'-biphenyl]-4-(phenylamino)propanenitrile and L -valine methyl ester. It is soluble in ethyl acetate, chloroform and methanol. N-[2'(2H)-tetrazol-[5' (phenylamino)

Naltrexone impurity E is an analytical standard that is used to calibrate high-performance liquid chromatography (HPLC) instruments. This substance is a natural metabolite of naltrexone, which is an opioid receptor antagonist, and has the chemical name of 4-hydroxy-3-methoxy-N-(5α,6β)-dimethyl-2-[(1R)-1-(3-methyloxetan-3-yl)piperidin-4-yl] benzeneacetamide. Naltrexone impurity E is a pharmacopoeia grade compound that can be used in the synthesis of drug products. Custom synthesis and natural or synthetic sources are available.

Cimetidine impurity F is a research and development, drug product, analytical, synthetic, natural, niche, HPLC standard and pharmacopoeia impurity.
CAS No. 55272-86-1

22-Oxo-vincaleukoblastine 6'-oxide is a synthetic drug with no known clinical use. It is an impurity of the vinca alkaloid drug vinblastine and may be found in small amounts in other vinca alkaloid drugs. 22-Oxo-vincaleukoblastine 6'-oxide is a metabolite of the vinca alkaloids, which are used as anticancer drugs. This substance has been shown to inhibit the metabolism of some cancer cells, leading to increased cell proliferation.

Atorvastatin impurity F is an impurity that can be found in atorvastatin. It is a white to off-white crystalline solid with a melting point of 142°C. It has a molecular weight of 273.5 and chemical formula of C14H13N3O2. This impurity can be found in atorvastatin as an API impurity, which may have an effect on the efficacy or toxicity of the drug product. Impurities are present in all pharmaceutical products and should be identified, characterized, and quantified for quality control purposes. Impurities are often unavoidable byproducts of the manufacturing process and can lead to potential safety concerns if they are not detected early on during drug development. The presence of impurities may also affect the pharmacological effects or therapeutic efficacy of the drug product.