APIs for research and impurities

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Methotrexate dimethylamide is a research and development impurity standard with high purity. It is a synthetic drug product that can be custom synthesized to meet the needs of the customer. Methotrexate dimethylamide has been used as an analytical standard for HPLC analysis and as a natural metabolite in metabolism studies. This compound is also known as 71074-44-7, CAS No. 71074-44-7, or Metabolite.

(S,S)-IsoValganciclovir hydrochloride is a drug product with a purity of 99.5% or greater that is used as a reference standard in drug development and analytical chemistry. It is metabolized to (2R,3R)-2-Amino-3-hydroxypropanoic acid by the enzyme valganciclovir hydrolase. The chemical name for (S,S)-IsoValganciclovir hydrochloride is 2-(Aminomethyl)valganciclovir. The CAS registry number for this compound is 1401562-13-7.

3'-[3-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-3,6-dihydro-5-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-3'-deoxythymidine is an analytical standard used in the R&D and drug development of 3'-azido derivatives of thymidine. It is a synthetic intermediate that has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV) replication and to inhibit intracellular HIV type 2 (HIV2) production in cultured cells. 3'-[3-(3-Azido-2,3,-dideoxy--b erythro--pentofuranosyl)-3,6--dihydro--5--methyl--2,6--dioxo--1(2H)--pyrimidinyl]-

Bendamustine isopropyl ester is a synthetic, high purity drug product. It is an impurity standard for the manufacture of Bendamustine hydrochloride, a drug product that is used in cancer chemotherapy. Bendamustine isopropyl ester has been shown to inhibit the metabolism of bendamustine hydrochloride and may be useful as a pharmacokinetic marker in clinical trials. Bendamustine isopropyl ester metabolizes into bendamustine hydroxypyridinium salt, which has been shown to have anti-inflammatory properties.

Desacetyl bisacodyl β-D-glucuronide is a drug product that is used as an impurity standard in analytical chemistry. It is a synthetic chemical that has been custom synthesized for research and development of drugs. The CAS number for this compound is 31050-47-2 and the molecular weight is 526.25 g/mol. This compound has not been approved by the FDA, but it has been shown to be pharmacologically active in animal studies. Desacetyl bisacodyl β-D-glucuronide can be ordered from our website at www.customsynthesislab.com

Torasemide EP Impurity C is a drug product that is used as an analytical standard in the metabolism studies of torasemide. Torasemide EP Impurity C belongs to the group of metabolites, and it has been shown to have pharmacopoeia standards. Torasemide EP Impurity C can be found in natural products, but also synthesized in laboratories.

N,5-Dibenzyl-5-hydroxy-indole-3-glyoxylamide is a drug product that can be used as an analytical reference standard and an impurity standard. It is used in the development of drugs, including synthetic intermediates and metabolites. N,5-Dibenzyl-5-hydroxy-indole-3-glyoxylamide is a natural metabolite. It has been shown to have antihistamine activity and to inhibit prostaglandin synthesis.

4-Methanesulfonyloxybutanol is a chemical substance with the molecular formula CH3SO2CH(CH2OH)CH2OH. It is used as an intermediate in the synthesis of 4-methanesulfonyloxybutanol, which is a potent inhibitor of busulfan-induced leukopenia and myelosuppression. This substance has been shown to be highly effective in preventing busulfan-induced side effects when administered intravenously. 4-Methanesulfonyloxybutanol is chemically synthesized by intramolecular alkylation of butanol, followed by hydrolysis. The reaction product can be detected using an ionization detector in conjunction with gas chromatography. This product is an alkylation agent that reacts with polypropylene to produce polypropylene glycols.

N-Benzyl N-demethyl trimebutine is an analytical standard that is used in the development of new drugs. It is a synthetic compound and has not been found in any natural sources. The CAS number for this compound is 1329834-94-7, and it can be purchased as an impurity standard or as a custom synthesis. N-Benzyl N-demethyl trimebutine has two impurities: benzyl alcohol and demethyltrihexyphenidyl. This compound can be used as a pharmacopoeia or HPLC standard.

1,5-Bis(4-pyridyl)pentane is a coordination polymer that can be used in the preparation of polymers. It is bifunctional and has coordination properties. This compound is made up of two pyridine rings linked to an ethyl group via a pentane chain. The cationic form of this compound is used for the preparation of some polymers. The crystal structure for 1,5-bis(4-pyridyl)pentane was determined by X-ray crystallography and found to have a layered topology with hydrogen bonding.

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Desmethyl dabrafenib is a synthetic drug product that is used in research and development. It is an impurity standard for dabrafenib, a prodrug of dabrafenib which has been shown to inhibit the growth of cancer cells by inhibiting the synthesis of proteins. Desmethyl dabrafenib is metabolized through CYP3A4/5-mediated oxidation and glucuronidation. It also undergoes phase I metabolism through CYP1A2 and 2C19, leading to formation of a major metabolite with no activity. This compound has been shown to have natural sources in plants such as rhubarb and soybeans.

Dioctyl carbonate is a pharmaceutical preparation used to treat skin conditions. It is a fatty acid ester of carbonic and carbonyl groups in which the two esters are in the same molecule. Dioctyl carbonate is a reaction product obtained by reacting an inorganic acid, such as hydrochloric acid or sulfuric acid, with an alcohol containing two hydroxyl groups and one double bond. This reaction may be facilitated by heating. The film-forming polymer may be polyvinylpyrrolidone, polyvinyl alcohol, or polyacrylic acid. Dioctyl carbonate has been shown to stimulate colony-stimulating factor production and inhibit the proliferation of human epidermal keratinocytes.

Phenothiazine S,S-dioxide is a fluorescent anion that can be used as a buffer. It has an absorption maximum at 514 nm in the visible region and a fluorescence emission maximum at 592 nm. Phenothiazine S,S-doxide blocks the emission of light from phosphor by absorbing the light and reemitting it at a longer wavelength. The luminescence intensity increases with increasing concentration of phenothiazine S,S-dioxide. This compound has been used to develop devices that detect anions in drinking water such as chloride ion. Phenothiazines are also known to have anti-inflammatory effects due to their ability to inhibit prostaglandin synthesis.

Carfilzomib is a drug product that belongs to the class of drugs called proteasome inhibitors. It has been used in the treatment of multiple myeloma, and is also being studied for use in other diseases such as chronic obstructive pulmonary disease and cystic fibrosis. Carfilzomib is an impurity standard for HPLC analysis and an analytical reference material. It is also used as a pharmacopoeia reference material. Carfilzomib is a natural product, with the synthetic route being developed by researchers at Pfizer. The drug product contains 2R,4S-diol as its main metabolite and impurity.

1-Phenyl-1,2,3,4-tetrahydro-isoquinoline is a synthetic compound which has been used as a lead compound for the development of drugs with dopamine β-hydroxylase inhibitory activity. In vitro studies have shown that 1-phenyl-1,2,3,4-tetrahydro-isoquinoline inhibits human serum dopamine β-hydroxylase and can be used to study the possible role of this enzyme in Parkinson's disease. This drug is racemized in the body and has been found to be effective against Parkinson's disease in rats. It is also an enantiomer that has industrial applications for the production of polyurethane foam insulation coatings.

o-Desphenyl sofosbuvir is a drug product that has been custom synthesized for research purposes. It is made of pure natural ingredients and does not contain any impurities. o-Desphenyl sofosbuvir is a metabolite from the synthesis of sofosbuvir, a drug used to treat hepatitis C. It can be used in pharmaceutical research and development as an analytical standard for HPLC.

Boc-3-hydroxy-1-adamantyl-glycine is a catalytic, nucleophilic, chiral amino acid that is used in the synthesis of oximes. Boc-3-hydroxy-1-adamantyl-glycine has been shown to be an effective substitute for hydroxylamine in reductive amination reactions and can be used to synthesize some pharmaceuticals, including saxagliptin. This compound is stable under standard conditions and can be easily synthesized. It is also a powerful nucleophile that reacts with electrophiles such as chloroformates and sulfonyl chlorides.

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Abt-639 hydrochloride is a drug product that is used as a research and development standard. It is a synthetic drug that has not been approved for any therapeutic use. Abt-639 hydrochloride is metabolized to yield an active metabolite, which has been identified in animal studies. The drug product contains an impurity standard of the natural metabolite, which can be used for pharmacopoeia and analytical purposes.

Ibuprofen EP impurity H is an impurity of ibuprofen. It is a white crystalline powder with a melting point of 182-184°C and a molecular weight of 253.3. Ibuprofen EP impurity H can be synthesized in high purity by reacting 4-bromobenzenesulfonyl chloride with 2-hydroxybenzoic acid in the presence of triethylamine. This impurity has been used as a standard for drug product analysis, pharmacopoeia standards, drug development, and metabolism studies. Ibuprofen EP impurity H can be identified by HPLC using a retention time of 17.2 minutes and an UV absorption maximum at 254 nm.

Disodium monooctyl sulfosuccinate (DSMS) is a sodium-based surfactant that is used as an excipient in tablets and capsules. DSMS can be used to treat infectious diseases, such as cholera, dysentery, and typhoid fever. It has been shown to be effective in treating these types of infections due to its long-term efficacy and low potency. The most common side effects of DSMS are mild skin irritation or an allergic reaction. This drug does not have any known contraindications with other drugs or foods. It is also biocompatible with a variety of polymers and fatty acids.

Deacetyl-N,o-didemethyldiltiazem is a drug product that is used for the treatment of hypertension. It is a synthetic compound and has not been found in nature. The impurity standard for this product is an analytical chemical that can be used to identify the presence of impurities in a sample. Deacetyl-N,o-didemethyldiltiazem can be synthesized from commercially available starting materials using custom synthesis methods. It is an API impurity and can be developed into a drug by researching and developing it as a niche therapy for hypertension. This compound has high purity and can be used as an HPLC standard.

Pravastatin diol lactone is a lipase inhibitor that prevents the hydrolysis of triglycerides in the intestines. It also inhibits the synthesis of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Pravastatin diol lactone has been shown to be effective in reducing serum cholesterol levels in animal models and inhibiting esterification of cholesterol by preventing the conversion of HMG-CoA to mevalonic acid, which is an important step in the synthesis of cholesterol. Pravastatin diol lactone is a polyketide that was discovered from a fungus and chemically altered to produce this drug.

Doxylamine N-oxide is a drug product that is custom synthesized to meet the specific needs of the customer. It has a purity of > 98% and is synthesized with natural starting materials. Doxylamine N-oxide inhibits bacterial growth through inhibition of protein synthesis, which may be due to its ability to inhibit methionine synthase. This drug also has been shown to be effective in the treatment of malaria, although it does not have significant anti-malarial properties. Doxylamine N-oxide has been used as a metabolite marker for other drugs and as an impurity standard for HPLC analysis.

(E,Z)-Epalrestat methyl ester is a drug product that is custom-synthesized for research and development purposes. It is a natural metabolite of (E,Z)-epalrestat acid. The chemical name for this compound is 3-[(2-chlorophenyl)methyl]-N-(1H-indol-3-ylmethylene)malonamide. The molecular weight of this compound is 284.87 g/mol and it has an empirical formula of C24H27ClN2O2. It has been found to inhibit the activity of phosphodiesterase (PDE), which plays a role in the breakdown of cyclic nucleotides such as cAMP and cGMP. This product has high purity and analytical data that can be used for metabolism studies or clinical trials.

9-(1,3-Dioxolan-2-ylmethyl)-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione is a metabolite of the drug 9-(1,3-Dioxolan-2-ylmethyl)-1,3,9 dihydrobenzo[g]pteridine. It is an impurity in the synthesis of 9-(1,3 Dioxolan 2 ylmethyl)-3,9 dihydrobenzo [g]pteridine. The purity of this compound is > 99%, with a melting point range of 233 to 235 °C and a molecular weight of 244.24 g/mol. It is soluble in methanol and acetonitrile. This compound has been characterized by IR spectroscopy (ATR), 1H NMR (400 MHz) spectroscopy (CDCl 3 ), and mass spectrometry (HRMS

Moexipril diketopiperazine is a drug product that is custom synthesized in a high purity and analytical grade. It is metabolized through metabolism studies and has been shown to have natural, synthetic, impurity and research and development standards. Moexipril diketopiperazine has CAS No. 103733-51-3. It has been shown to be a metabolite of Moexipril hydrochloride, which is an angiotensin II receptor antagonist used to treat hypertension and congestive heart failure. This product is also used as a standard for HPLC analysis.

5α,6α-Epoxycholestanol-d7 is an impurity of a cholestatic drug product. It can be used as a research and development standard or as an impurity standard in the production of drugs. 5α,6α-Epoxycholestanol-d7 has been characterized by GC/MS and HPLC techniques. This compound is also useful for pharmacopoeia purposes, drug development, and metabolic studies.

Propoxyphenyl thiosildenafil is a linker that has been synthesized from the amino acid sildenafil. The compound can be used in pharmaceutical preparations, health food, and medicinal preparations. It is also used as an additive to prepare the desired drug. This product is a resonance-type organic compound that can be detected using resonance spectroscopy or magnetic resonance spectroscopy. The compound has a molecular weight of 348.08 g/mol and a boiling point of 440°C at 760 mmHg pressure.

Terbutaline impurity b is a pharmacopoeia grade drug product that is used as an analytical standard. It is also used in the synthesis of terbutaline, which is a drug that has been approved by the FDA to treat bronchospasm, asthma and other lung disorders. Terbutaline impurity b may be found in natural sources or may be synthesized. This impurity can be custom synthesized using HPLC-grade reagents and can be obtained at high purity levels.

Diethyl methylphenylmalonate is a halogenated organic compound that can be prepared by the reaction of magnesium with diethyl malonate and methylbromide. Diethyl methylphenylmalonate is used as a ligand in coordination chemistry and as a catalyst in organic reactions. The mechanism of this chemical's action is unknown, but it has been shown to be hydrophobic and to bind to microbial cells. It also has been demonstrated to have an oxidation catalyst activity. Diethyl methylphenylmalonate can be synthesized from vitamin b12, piperazine, and solid catalyst irradiation or electrolysis.

17-o-(Acetyl-d3)-6-methylprednisolone is a drug product that belongs to the group of corticosteroids. It is used for the treatment of inflammatory conditions and autoimmune diseases. This API is used as an impurity standard in analytical methods such as HPLC, and it can be synthesized from natural sources or synthetically. 17-o-(Acetyl-d3)-6-methylprednisolone can also be used in R&D for the development of drugs targeting niche markets, such as those with high purity requirements.

Naproxen Impurity C is an analytical impurity that is found in Naproxen. It is a white crystalline powder with a melting point of 210°C and an assay of 99%. It has been shown to be a metabolite of Naproxen, and may have therapeutic value for the treatment of pain, inflammation, or fever. The purity of this product has been verified by HPLC analysis.

Meloxicam is a nonsteroidal anti-inflammatory drug that is used in the treatment of osteoarthritis and rheumatoid arthritis. It has been shown to reduce the number of exacerbations in patients with juvenile idiopathic arthritis. Meloxicam also inhibits the production of Cox-2, which is an enzyme that produces inflammation in joints. The oral route of administration allows meloxicam to be distributed through the body. This drug is not active against ankylosing spondylitis and it should not be taken by pregnant women or children under 12 years old.

(-)-Bornyl ferulate is a natural compound, specifically a type of ferulic acid ester, which is a secondary metabolite found in certain plants. Its source is primarily the essential oils and resins of various coniferous species, where it contributes to the plant's defense mechanisms. The mode of action of (-)-Bornyl ferulate involves its ability to scavenge free radicals, thus exhibiting antioxidant activity. It also modulates inflammatory pathways, suggesting possible anti-inflammatory effects.

O-Acetyl silodosin is a synthetic, natural metabolite of silodosin. It is a nicotinic acid derivate that inhibits the activity of phosphodiesterase type 5 (PDE5) and has been used as a research and development standard for PDE5 inhibitors. O-Acetyl silodosin is an impurity in the commercial drug product, Silodosin®.

3-Keto fluvastatin sodium is a high purity, analytical, API impurity, HPLC standard, Drug development, niche, drug product and Impurity standard. 3-Keto fluvastatin sodium is used in the research and development of drugs. It is also used in the analysis of pharmaceuticals and other chemicals. 3-Keto fluvastatin sodium has been shown to have pharmacological properties with respect to lowering cholesterol levels.

Leuprolide acetate ep impurity F is a drug product that is an impurity standard for the leuprolide acetate API. It is used in analytical and clinical studies to identify the presence of leuprolide acetate impurities, as well as to determine the metabolism of leuprolide acetate. Leuprolide acetate ep impurity F has been shown to be a natural metabolite of leuprolide acetate and have a niche application in pharmacopoeia.

Dispersants are substances that are used to break up and disperse particles in a liquid. The dispersant 11-[3-(dimethylamino)propyl]-6,11-dihydrodibenz[b,e]oxepin-11-ol is an active substance that is used in the production of granules, tablets or other solidified forms of medicaments. It is a substance that has a physiologically active effect on humans and animals. This product can be applied as droplets or particles.

Esomeprazole Impurity Q is a drug product. It is an impurity standard of esomeprazole, CAS No. 131428-60-1, which is used in the development of drugs and as an analytical reagent. It is synthesized from natural materials and has a purity of 99%. The metabolite can be found in animal and human metabolism studies. Esomeprazole Impurity Q is used for niche purposes such as HPLC standards, analytical reagents, or pharmacopoeia reference substances.

5-O-Desethyl amlodipine is a metabolite of amlodipine. It has been used as an analytical reference standard for the determination of amlodipine and its metabolites in human plasma and urine. 5-O-Desethyl amlodipine has been reported to be excreted in human breast milk at a concentration that is about 20% of that found in maternal plasma. The drug product is manufactured by HPLC and is classified as a high purity pharmaceutical drug, which means it is free from extraneous substances such as other drugs, proteins, or bacteria.

This is a white crystalline compound that has been shown to be effective against glutamic acid-sensitive L-amino acid decarboxylase. It is used as an intermediate in the synthesis of other pharmaceuticals.

(2S,2R,Trans)-saxagliptin is an anti-diabetic drug that belongs to the thiazolidinedione class of drugs. It is a synthetic compound that is metabolized by cytochrome P450 enzymes and excreted in urine. (2S,2R,Trans)-saxagliptin has been shown to inhibit the synthesis of glucose in liver cells and to lower blood glucose levels in diabetic animals. In addition, it has been shown to have anti-inflammatory effects by inhibiting the production of TNF-α and IL-6 cytokines.

(2S,4R)-Fosinopril sodium salt is a prodrug that is converted to the active form fosinopril in the body. It is used to treat high blood pressure and heart failure. Fosinopril inhibits angiotensin-converting enzyme (ACE) and blocks the conversion of angiotensin I to angiotensin II. This leads to an increase in the production of a vasodilator called nitric oxide, which relaxes and widens blood vessels. Fosinopril also has been shown to have adverse effects on liver function, including increased liver enzymes and liver damage, as well as drug interactions with other nonsteroidal anti-inflammatory drugs (NSAIDs).