APIs for research and impurities
Active Pharmaceutical Ingredients (APIs) are the substances in drugs responsible for their therapeutic effects. In this section, you will find a wide variety of APIs intended for research use. These compounds are essential for the development, testing, and validation of new pharmaceutical formulations. CymitQuimica offers high-quality APIs to support research in drug discovery and development.
Subcategories of "APIs for research and impurities"
- Aminoacids and derivatives(12,440 products)
- Anthraquinones and derivatives(407 products)
- Benzimidazole and Imidazole Derivatives(10,464 products)
- Benzodiazepine Derivatives(335 products)
- Carbohydrates and glycoconjugates(5,388 products)
- Esters and Derivatives(42,306 products)
- Fatty Acids and Lypidic Derivatives(32,486 products)
- Flavonoids and Polyphenols(17,100 products)
- Free Radicals and Oxidant/Reducing Agents(214 products)
- Ketones and derivatives(2,692 products)
- Natural and semi-synthetic antibiotics(6,409 products)
- Nitriles and Cyano Derivatives(3,070 products)
- Nitrosamines and Derivatives(55 products)
- Nucleosides and Nucleotides(3,492 products)
- Organic Phosphates and Phosphonates(1,203 products)
- Organic Sulphonates and Sulphates(10,451 products)
- Organometallics(4,425 products)
- Others(6,340 products)
- Peptides and Proteins(3,164 products)
- Polymers and Derivatives(100 products)
- Purines and Pyrimidine Derivatives(8,974 products)
- Quinazoline and Quinoline Derivatives(66,217 products)
- Quinones and Derivatives(24,378 products)
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)(92,938 products)
- Steroids and Derivatives(4,987 products)
- Sulfonamides and Derivatives(2,607 products)
- Terpenoids and Derivatives(3,860 products)
- Thiazolidinediones and Thiopyrans(2,755 products)
- β-Adrenergic Compounds(231 products)
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Found 66870 products of "APIs for research and impurities"
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Decitabine impurity 13
CAS:Decitabine is a drug product that is being developed for the treatment of cancer. It has been shown to inhibit the proliferation of human tumor cells in vitro and to induce apoptosis in prostate cancer cells. Decitabine is metabolized to an active form, dideoxycitidine (DDC), which binds to DNA and inhibits the enzyme DNA polymerase alpha, leading to inhibition of DNA synthesis. Impurity 13 is a by-product of the synthesis process and can be used as an analytical standard. It can also be used as a research and development impurity standard or as a pharmacopoeia impurity standard.Formula:C4H6N6O2Purity:Min. 95%Molecular weight:170.13 g/molGliclazide impurity F
CAS:Gliclazide is a sulfonylurea drug that is used to treat type 2 diabetes. The impurity F, which is an impurity standard, can be synthesized by reacting 1-chloro-2,6-difluoroaniline with sodium methoxide in methanol. It is also an API impurity found in the synthesis of gliclazide and can be custom synthesized for research and development purposes. Gliclazide impurity F has a CAS number of 1076198-18-9 and the molecular formula C8H4ClF3NOS. This product has a purity of >99% and is classified as synthetic. It has been shown to have pharmacopoeia activity and can also be used for niche applications such as drug development.Formula:C15H21N3O3SPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:323.41 g/mol2-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene
CAS:2-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene is a synthetic compound that has been used as an impurity standard for the drug product and API. It has also been used for the pharmacopoeia, research and development, and analytical purposes. This compound is a metabolite of erythromycin.Formula:C18H19NOSPurity:Min. 95%Color and Shape:White To Pink Or Yellow SolidMolecular weight:297.42 g/molN-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]
CAS:Poloxamer 407 is a synthetic, non-biodegradable polymer that is used as a surfactant in pharmaceutical preparations. It is typically used to solubilize poorly water-soluble drugs. Poloxamer 407 has been shown to inhibit angiotensin II type 1 receptor blockers and hydrochloric acid, which are involved in the production of stomach acid and regulate blood pressure. The chloride ions present in this polymer are also responsible for its antibacterial properties. It has been shown to be effective against bacteria such as Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus. This polymer can also be used as an active targeting agent for drug delivery systems by attaching it to other molecules with specific biological activities. Poloxamer 407 is soluble in organic solvents that are commonly found in the environment such as halides (e.g., chloride). This polymer also hydrolyzes under basic conditions into potassium ionFormula:C31H35N5O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:525.64 g/mol2-[[3-(Trifluoromethyl)phenyl]amino] benzoic acid 2-hydroxyethyl ester
CAS:2-[[3-(Trifluoromethyl)phenyl]amino] benzoic acid 2-hydroxyethyl ester is a metabolite of the drug desloratadine. It is used as an impurity standard in HPLC and as a metabolite to study metabolism.
Formula:C16H14F3NO3Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:325.28 g/mol1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3] oxazine-3-butanoic acid sodium
CAS:Fluoxetine is a selective serotonin reuptake inhibitor that is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa, panic disorder, premenstrual dysphoric disorder (PMDD), and social anxiety disorder. It is also used as an appetite suppressant in some countries. Fluoxetine inhibits the neuronal uptake of serotonin by blocking the presynaptic transporter protein. The most common adverse effects are nausea, diarrhea, drowsiness, dry mouth, blurred vision and sexual dysfunction.Formula:C33H35FN2O7•NaPurity:Min. 95%Color and Shape:PowderMolecular weight:613.63 g/mol3-[Methyl(phenylmethyl)amino]-1-phenyl-1-propanone hydrochloride
CAS:Nisoxetine is a norepinephrine (NE) reuptake inhibitor that is used as an antidepressant. It has been shown to be a potent and selective NE reuptake inhibitor with a high affinity towards the NE transporter in rat brain synaptosomes, with potency several times higher than that of tricyclic antidepressants. Nisoxetine's major advantage over other antidepressants is its high efficiency, which makes it suitable for large-scale production. The synthesis of nisoxetine involves two steps: 1) reaction of 3-[methyl(phenylmethyl)amino]-1-phenyl-1-propanone hydrochloride with toluene to form the corresponding methyl ester and 2) hydrogenation of the methyl ester to form nisoxetine. This synthesis is efficient, stable, and chiral due to the use of bimetallic catalysts.Formula:C17H19NO•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:289.8 g/mol5-Aminolevulinic acid hexyl ester hydrochloride
CAS:5-Aminolevulinic acid hexyl ester hydrochloride is a cytotoxic drug that inhibits the growth of cancer cells. It is used to diagnose and treat certain cancers, including squamous cell carcinoma, skin cancer, and some types of lung cancer. 5-Aminolevulinic acid hexyl ester hydrochloride can be used in conjunction with fluorescein angiography to detect blood vessels in the skin or other tissues. This drug has also been shown to have anti-inflammatory properties that may be useful for the treatment of autoimmune diseases.Formula:C11H22NO3ClPurity:Min. 95%Color and Shape:White PowderMolecular weight:251.75 g/mol4-(2,3,4-Trimethoxybenzyl)piperazine-1-carbaldehyde hydrochloride
CAS:4-(2,3,4-Trimethoxybenzyl)piperazine-1-carbaldehyde hydrochloride is a custom synthesis that is used as a drug product, impurity standard and metabolic studies. The compound has been shown to be metabolized via oxidation by cytochrome P450 enzymes. It also binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Formula:C15H22N2O4·HClPurity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:330.81 g/molN-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide sodium salt
CAS:2-Nitroacetamide sodium salt is an impurity of the drug N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide, a synthetic chemotherapeutic agent for the treatment of cancers. This compound has been shown to have metabolism studies and natural properties. It has a CAS number of 112251-56-6 and is found in the pharmacopoeia. 2-Nitroacetamide sodium salt is a custom synthesis that can be used as a reference standard for HPLC analysis. It can also be used as a drug product or metabolite in drug development.
Formula:C12H18N3O4SNaPurity:Min. 95%Color and Shape:PowderMolecular weight:323.34 g/molTyrosol glucuronide
CAS:Tyrosol is a phenolic compound found in olive oil and other plant sources. It has been shown to have antioxidant, anti-inflammatory, and anti-cancer activities. Tyrosol glucuronide is the main form of tyrosol found in urine samples. The absorption process of tyrosols is due to their uptake by the liver cells, where they are converted into fatty acids and then conjugated with glucuronic acid. Tyrosols are also metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Studies have shown that tyrosols can help lower blood pressure and improve insulin resistance in women.Formula:C14H18O8Purity:Min. 95%Color and Shape:PowderMolecular weight:314.29 g/molBis[N-[2-[[[5-[(dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-N'-methyl-2,2-diamino-1-nitroethenyl]methane
CAS:Impurity arising druring the synthesis of ranitidineFormula:C27H44N8O6S2Purity:Min. 95%Color and Shape:Orange PowderMolecular weight:640.82 g/molOlsalazine sodium impurity C
CAS:Olsalazine sodium impurity C is a metabolite of olsalazine sodium. It is a natural product that can be custom synthesized for research and development purposes. Olsalazine sodium impurity C has been shown to have pharmacopoeia-grade purity and can be used as an analytical standard or an API impurity in drug products. The CAS number for this substance is 259151-72-9.
Formula:C13H10N2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:258.23 g/molN-Acetyldesloratadine
CAS:N-Acetyldesloratadine is a second generation antihistamine that has high affinity for histamine H1 receptors. It is an orally active drug that is used to treat allergic rhinitis, chronic idiopathic urticaria, and pruritus. N-Acetyldesloratadine has been shown to inhibit platelet aggregation in vitro and in vivo. This activity may be due to the drug's ability to bind with high affinity to histamine receptor sites on the membranes of platelets, thereby inhibiting the binding of adenosine diphosphate (ADP) to its receptor site. N-Acetyldesloratadine also inhibits the release of serotonin from mast cells and basophils in vitro.Formula:C21H21ClN2OPurity:Min. 95%Molecular weight:352.9 g/mol2-EPIIvermectin B1a
2-EPIivermectin B1a is a drug product that is used as an analytical standard for the detection of impurities in API and in the synthesis of Metabolite. It is also used as a natural product for drug development. 2-EPIivermectin B1a is not intended for use as an active pharmaceutical ingredient. This product has been shown to have pharmacopoeia purity, which means it meets the specifications set by the following organizations: USP, EP, JP, BP, and CP.Purity:Min. 95%5-Methoxy-2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole
CAS:5-Methoxy-2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H benzimidazole is a synthetic drug product. It has been used as a positive control in metabolism studies and as an impurity standard. 5-Methoxy 2-[(4-chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfinyl]-5 methoxy 1H benzimidazole is also a metabolite of the active pharmaceutical ingredient (API) which is used to develop drugs. This chemical is synthesized by custom synthesis and can be obtained at high purity levels. The metabolite of this compound is 5 methoxy 2-[(4 chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfonyl]-5 methoxy 1H benzimidazole.
Formula:C16H16ClN3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:349.84 g/molOxytocin
CAS:Natriuretic hormone; induces uterine contraction and lactation
Formula:C43H66N12O12S2Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:1,007.19 g/molFluticasone furoate impurity F
Fluticasone furoate impurity F is a synthetic, high-purity, pharmacopoeia grade drug product. It has been developed for research and development purposes only. Impurity standard: Fluticasone furoate impurity F is a metabolite of fluticasone furoate. Synthetic: Fluticasone furoate impurity F is a synthetic compound that has been custom synthesized to meet your requirements. Drug Development: Fluticasone furoate impurity F has been developed as a drug product to be used in the development of new drugs. Metabolism Studies: Fluticasone furoate impurity F can be used in metabolism studies and analytical determinations.END>>Purity:Min. 95%N-Despropyl ropinirole hydrochloride
CAS:N-Despropyl ropinirole hydrochloride is a synthetic drug product that is used as a research and development impurity standard. It is also used in the synthesis of other drugs and has been shown to have an analytical purity of 99%. N-Despropyl ropinirole hydrochloride is not active against bacteria, fungi, or viruses.Formula:C13H19ClN2OPurity:Min. 95%Color and Shape:PowderMolecular weight:254.75 g/mol
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![5-Methoxy-2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIM57916.webp&w=3840&q=75)
