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APIs for research and impurities

APIs for research and impurities

Active Pharmaceutical Ingredients (APIs) are the substances in drugs responsible for their therapeutic effects. In this section, you will find a wide variety of APIs intended for research use. These compounds are essential for the development, testing, and validation of new pharmaceutical formulations. CymitQuimica offers high-quality APIs to support research in drug discovery and development.

Subcategories of "APIs for research and impurities"

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Found 58049 products of "APIs for research and impurities"

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  • (2S,2R,Trans)-saxagliptin

    CAS:

    (2S,2R,Trans)-saxagliptin is an anti-diabetic drug that belongs to the thiazolidinedione class of drugs. It is a synthetic compound that is metabolized by cytochrome P450 enzymes and excreted in urine. (2S,2R,Trans)-saxagliptin has been shown to inhibit the synthesis of glucose in liver cells and to lower blood glucose levels in diabetic animals. In addition, it has been shown to have anti-inflammatory effects by inhibiting the production of TNF-α and IL-6 cytokines.

    Formula:C18H25N3O2
    Purity:Min. 95%
    Molecular weight:315.40 g/mol

    Ref: 3D-PMC26598

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  • N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride

    CAS:

    N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride is an impurity in the synthesis of N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N'-methylpropylenediamine formamide hydrochloride. It is a white solid that can be used as an analytical reference standard for HPLC. It has been detected in the urine of people taking this drug and can be used to identify the presence of this drug in urine samples.

    Formula:C14H17N5O2·HCl
    Purity:Min. 95%
    Molecular weight:323.78 g/mol

    Ref: 3D-IA156915

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  • Methyl mycophenolate impurity E

    CAS:

    Methyl mycophenolate impurity E is a reactive, propargylamine-containing, monosodium salt with immunosuppressive properties. It is used in the treatment of cancer by inhibiting the production of white blood cells, which are needed to fight infection. Methyl mycophenolate impurity E has shown antitumor activity and can be used for the treatment of some types of cancer. It is metabolized in vivo to methyl mycophenolate and inhibits protein synthesis by alkylating DNA.

    Formula:C18H22O6
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:334.36 g/mol

    Ref: 3D-IM25526

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  • Deschloro amlodipine

    CAS:

    Deschloro amlodipine is a drug that is used for the treatment of high blood pressure. It belongs to a group of drugs called calcium channel blockers. Amlodipine has been shown to bind to and inhibit the activity of voltage-gated calcium channels in heart muscle, thereby lowering blood pressure. Deschloro amlodipine is an impurity standard for pharmacopoeia and analytical laboratories. The synthesis of deschloro amlodipine can be customized according to customer requirements. This product will be shipped as soon as possible after purchase.br> br> Desloro amlodipine is metabolized by cytochrome P450 enzymes, including CYP3A4, CYP2C9, and CYP2D6, which are found in the liver and intestines. These enzymes convert desloro amlodipine into two metabolites: 4-hydroxyamlodipine and 4

    Formula:C20H26N2O5
    Purity:Min. 95%
    Molecular weight:374.43 g/mol

    Ref: 3D-NDA15052

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  • rac-Pregabalin N-acrylamide

    CAS:

    Pregabalin is an anticonvulsant drug that is used to treat epilepsy, neuropathic pain, and generalized anxiety disorder. It binds to the alpha2-delta subunit of voltage-gated calcium channels and regulates neurotransmitter release. Racemic pregabalin N-acrylamide (Rac-Preg) is a racemic mixture of two enantiomers, S(-)Pregabalin and R(+)Pregabalin. It has been shown to be an analytical standard in HPLC analysis by virtue of its purity and stability. Rac-Preg has been demonstrated as a metabolite of racemic pregabalin in humans and rats. Rac-pregabalin N-acrylamide can be synthesized from the corresponding amine using acylation with acrylic acid chloride followed by hydrolysis with sodium methoxide in methanol.

    Formula:C11H19NO3
    Purity:Min. 95%
    Molecular weight:213.27 g/mol

    Ref: 3D-VJC84428

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  • Salbutamol Impurity D

    CAS:

    Salbutamol Impurity D is a chiral, metal chelator impurity of the drug substance Salbutamol. It is a prodrug that is hydrolyzed to its active form, salbutamol sulfate, in vivo. Salbutamol Impurity D binds to chloride ions and has been shown to be an interferent for many analytical methods. The reversed-phase chromatography retention time for Salbutamol Impurity D is about 10 minutes shorter than for Salbutamol sulfate.

    Formula:C13H19NO3
    Purity:Min. 95%
    Molecular weight:237.29 g/mol

    Ref: 3D-FS170974

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  • N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide

    CAS:

    N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide is a drug product that is used in the development of new drugs. It is an analytical standard for HPLC and was created as a natural metabolite from the antibiotic Cefazolin. N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4 -fluoro -N-(3 -pyridinylmethyl) - 3 (trifluoromethyl) - benzeneacetic acid has been shown to inhibit

    Formula:C32H27F4N5O3
    Purity:Min. 95%
    Molecular weight:605.6 g/mol

    Ref: 3D-YTA72268

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  • (9Z)-Roxithromycin

    CAS:

    Roxithromycin is a macrolide antibiotic that inhibits protein synthesis in bacteria. It binds to the 50S ribosomal subunit, thereby inhibiting bacterial growth. Roxithromycin has been used to diagnose intestinal and esophageal diseases, inflammatory diseases, and cancer. There are some cardiac effects associated with Roxithromycin that may be related to its ability to inhibit serotonin reuptake. This drug also has anti-inflammatory properties and has been shown to be effective against influenza virus infections as well as other infectious diseases such as tuberculosis and HIV/AIDS.

    Formula:C41H76N2O15
    Purity:Min. 95%
    Molecular weight:837.05 g/mol

    Ref: 3D-IR106421

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  • 1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid

    CAS:

    1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid (1bRT) is an amide that inhibits the growth of viruses by inhibiting the viral enzyme thiosemicarbazide. It has been shown to be active against specific viruses such as HIV and retroviruses. 1bRT is used to treat lung diseases caused by viruses, including bronchiolitis, pneumonia, and pulmonary fibrosis. It also has antibacterial properties. Studies have shown that 1bRT reduces the number of bacteria in body fluids and helps to prevent respiratory infections and other bacterial infections in people with weakened immune systems due to AIDS or cancer treatment.

    Formula:C8H11N3O5
    Purity:Min. 95%
    Molecular weight:229.19 g/mol

    Ref: 3D-IR138822

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  • RS 67506 hydrochloride

    CAS:

    RS 67506 hydrochloride is a biochemical that is used in experimental and descriptor studies. The ketone group has been found to be an important part of the molecular structure. RS 67506 hydrochloride has been shown to have a number of biological properties, including inhibition of the synthesis of neurotransmitters such as dopamine, serotonin and norepinephrine; it also has anti-nervous system activity. This chemical was also found to inhibit the synthesis of prostaglandin E2 in human neutrophils. It is hypothesized that RS 67506 hydrochloride may inhibit phospholipase A2, which would prevent the release of arachidonic acid from phospholipids into the cell membrane and block the production of eicosanoids.

    Formula:C18H29Cl2N3O4S
    Purity:Min. 95%
    Molecular weight:454.4 g/mol

    Ref: 3D-TGA98661

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  • 6-Bromo-6-dehydro-17a-acetoxy progesterone

    Controlled Product
    CAS:
    6-Bromo-6-dehydro-17a-acetoxy progesterone is a drug product that can be used as an HPLC standard or as a synthetic intermediate. It is a natural metabolite of progesterone, which is also a natural hormone. 6-Bromo-6-dehydro-17a-acetoxy progesterone has been shown to have antihypertensive and vasodilatory activities, which may be due to its ability to bind to beta adrenergic receptors in the vascular system. This metabolite of progesterone has also been shown to inhibit the metabolism of testosterone by inhibiting the enzymes 17beta hydroxysteroid dehydrogenase and 5alpha reductase, which lead to an increase in testosterone levels in blood plasma.
    Formula:C23H29BrO4
    Purity:Min. 95%
    Molecular weight:449.38 g/mol

    Ref: 3D-IB19164

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  • Ly 2389575 hydrochloride

    CAS:

    Ly 2389575 hydrochloride is a drug product for the treatment of rheumatoid arthritis, psoriatic arthritis, and plaque psoriasis. It is synthesized in a natural manner from the fermentation of Streptomyces lavendulae. The compound has been shown to be metabolized through a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Ly 2389575 hydrochloride also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

    Formula:C15H16BrCl3N4
    Purity:Min. 95%
    Molecular weight:438.6 g/mol

    Ref: 3D-KKB10409

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  • Tolterodine S-enantiomer

    CAS:

    Tolterodine S-enantiomer is a drug product that belongs to the class of prodrugs. It is metabolized in vivo to the active form, tolterodine. Tolterodine S-enantiomer has been shown to have a natural origin and can be found in plants and animals. Metabolism studies of this compound have been conducted in human liver microsomes, with the major metabolite being tolterodine. Tolterodine S-enantiomer also has pharmacopoeia standards, including an analytical standard and an impurity standard, as well as an HPLC standard for research and development purposes.

    Formula:C22H31NO·C4H6O6
    Purity:Min. 95%
    Molecular weight:475.57 g/mol

    Ref: 3D-YJB55103

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  • (S)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid

    CAS:

    (S)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a synthetic compound that is used as an impurity standard for HPLC. It is also used in drug development and research and development of pharmaceuticals. This product was made through custom synthesis and is not natural.

    Formula:C9H12N2O4S
    Purity:Min. 95%
    Molecular weight:244.27 g/mol

    Ref: 3D-IO145580

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  • Tetracosanoic-d47 acid

    Controlled Product
    CAS:

    Tetracosanoic acid is a drug product that is used in the development of drugs and as an analytical standard. Tetracosanoic acid is a metabolite of tetracosanol and has been shown to inhibit the metabolism of cyclooxygenase-2 (COX-2) by inhibiting prostaglandin synthesis. Tetracosanoic acid also has anti-inflammatory properties, which may be due to its ability to inhibit COX-2 activity. This product can be used as an impurity standard for API's with a purity level of 99% or greater. Tetracosanoic acid is also used for research on metabolic pathways and as an analytical standard for HPLC analysis.

    Formula:C24HD47O2
    Purity:Min. 95%
    Molecular weight:415.93 g/mol

    Ref: 3D-TCA06000

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  • Pirtenidine

    CAS:

    Pirtenidine is a potent and selective kinase inhibitor that has been shown to inhibit the activity of cyclin-dependent kinases. It has demonstrated promising results in preclinical studies as an anticancer agent, inducing apoptosis in cancer cells. Pirtenidine is an analog of protein kinase inhibitors, which have been used to treat various types of tumors. It has been found to be effective against human cancer cell lines and has shown significant tumor growth inhibition in animal models. Pirtenidine has also been reported to be a potent urine inhibitor of Chinese hamster ovary cells, making it a promising candidate for the treatment of urinary tract cancers.

    Formula:C21H38N2
    Purity:Min. 95%
    Molecular weight:318.5 g/mol

    Ref: 3D-DEA92327

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  • 4-Desmethyl 5-methyl vortioxetine hydrochloride

    CAS:

    Please enquire for more information about 4-Desmethyl 5-methyl vortioxetine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C18H23ClN2S
    Purity:Min. 95%
    Molecular weight:334.9 g/mol

    Ref: 3D-MKD72214

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  • Alfuzosin hydrochloride EP Impurity F hydrochloride

    CAS:

    Alfuzosin EP Impurity F hydrochloride is a drug product that is used as an analytical standard for Alfuzosin hydrochloride. It is a natural, synthetic, and impurity standard that exhibits similar chromatographic properties to the API. The CAS number of this impurity is 19216-68-3. This product has a niche market because it is used in metabolism studies. It also exhibits high purity and pharmacopoeia grade quality.

    Formula:C12H16N4O2•HCl
    Purity:Min. 95%
    Molecular weight:284.74 g/mol

    Ref: 3D-IA182629

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  • 2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene

    CAS:

    2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene is an impurity found in sulfasalazine. It is a metabolite that is formed by the P450 system in the liver. The metabolic process of 2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene has been studied in detail and has been shown to be a major contributor to the pharmacokinetic profile of sulfasalazine. This substance also exhibits antimicrobial activity and inhibits the growth of bacteria, fungi, and viruses.

    Formula:C17H14N4O3S
    Purity:Min. 95%
    Molecular weight:354.38 g/mol

    Ref: 3D-IP27340

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  • Trazodone Hydrochloride BP Impurity A

    CAS:
    Trazodone Hydrochloride BP Impurity A is an unproven impurity of Trazodone. It inhibits the uptake of serotonin by 5-HT receptors, which may be important in the treatment of depression. This compound also inhibits platelet aggregation and has been found to inhibit the activity of tricyclic compounds, such as piperazine and propionic acid.
    Formula:C19H22CIN5O2
    Purity:Min. 95%
    Molecular weight:491.33 g/mol

    Ref: 3D-IT171024

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