APIs for research and impurities

<p>Pantoprazole is a proton pump inhibitor. It is used in the treatment of gastroesophageal reflux disease and other conditions involving excessive stomach acid production. The chemical name for Pantoprazole impurity is (E)-1-(4-chlorophenyl)ethyl-3-[(pyrrolidin-2-yl)oxy]propanediol. This substance is an enantiomer of pantoprazole, which has been determined to be inactive. Pantoprazole impurity can be identified by its melting point, crystallizing habit, and optical rotation. Active carbon filtration can be used to remove this substance from the final product.</p>

<p>Methyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide (MTBC) is a drug target that is a carboxylate. MTBC has been shown to have potent inhibition activity against benzothiazine oxidases. MTBC can be used as an inhibitor of enzymes involved in the biosynthesis of benzothiazines and may be useful for the treatment of diseases such as Parkinson's disease and schizophrenia. The inhibition potential of MTBC has been unraveled through its interaction with peroxidases and other oxidases. In vitro studies have shown that MTBC can inhibit the oxidation of low molecular weight compounds by acting as a scavenger for hydrogen peroxide. This drug also exhibits unsymmetrical dehydration to produce methyl 4-(hydroxyamino)-2H-1,2-benzothiazine 1,1-dioxoate (MTBA), which is an</p>

<p>Please enquire for more information about Pregabalin inhouse impurity (RS-mme) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol (1SA2AP) is a glycerophospholipid that is the major phosphatidylinositol in platelets. 1SA2AP is hydrolyzed by phospholipase A2 into arachidonic acid and 1,2-diacylglycerol. The selectivity of 1SA2AP for ionization mass spectrometry has been demonstrated using ethanolamine and choline as standards. In this study, a kinetic method was used to determine the sensitivity and selectivity of electrospray ionization mass spectrometry for 1SA2AP. Analytical results were obtained from data collected from the analysis of two samples containing different concentrations of 1SA2AP.</p>

<p>Please enquire for more information about 1-(2-Pyridinyl)cyclobutylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>HMR 1826 is an analog of a medicinal compound that has been shown to have potent anticancer activity. It is a protein kinase inhibitor that induces apoptosis in cancer cells, particularly those of Chinese origin. HMR 1826 has been shown to be effective against a variety of tumors, and it works by inhibiting kinases involved in cell growth and division. In addition, HMR 1826 has been found to be present in human urine, which suggests that it may have potential as a diagnostic tool for cancer. The development of HMR 1826 and other kinase inhibitors represents an exciting new approach to the treatment of cancer, and ongoing research continues to investigate their potential therapeutic applications.</p>

<p>Dexamethasone EP Impurity K is an analytical standard for impurities in the drug product Dexamethasone EP. It is a synthetic methanolic solution of dexamethasone and a metabolite, which is chemically identical to the natural form. The purity of this impurity standard is 99.9%. This synthetic impurity is used for HPLC analysis as a pharmacopoeia-grade reference material.</p>

<p>5-(Aminosulfonyl)-2-methoxy-benzoic acid methyl ester is a synthetic compound that is used for pharmaceutical preparations. It is typically prepared by the reaction of ethylene and chloroacetic acid in the presence of an organic solvent. The reaction time can be adjusted to produce the desired amount of 5-(aminosulfonyl)-2-methoxy-benzoic acid methyl ester. This synthetic compound has been shown to have a high yield, with minimal contaminating impurities. It has also been shown to be effective in both pharmaceutical dosage and calibration.</p>

<p>m-Glimepiride impurity is a chemical substance that belongs to the sulfonylurea family. It is used as a pharmaceutical agent for the treatment of type 2 diabetes. The impurity was found in crystalline form and analyzed by HPLC-DAD and HPLC-MS. The purity of m-Glimepiride impurity was determined to be 99%. It is not known whether this impurity has any biological activity.</p>

<p>5Alpha-Androstan-3alpha,11beta-diol-17-one 3-glucosiduronate is a metabolite of testosterone. It is used as an analytical reference for the determination of testosterone in biological matrices. 5Alpha-Androstan-3alpha,11beta-diol-17-one 3-glucosiduronate is also a component of the United States Pharmacopeia (USP) reference standard for testosterone. This product has been synthesized by our R&amp;D department and can be custom manufactured to your specifications.</p>

<p>8-[2-(Diphenylmethoxy)-N-methylethylamino]-1,3-dimethylxanthine is a drug product that is used as an HPLC standard and as a metabolite in drug development. It is a natural product that has been found to be a potent inhibitor of phosphodiesterase (PDE) type IV. 8-[2-(Diphenylmethoxy)-N-methylethylamino]-1,3-dimethylxanthine can be synthesized from the corresponding phenol derivative through oxidation with potassium permanganate followed by treatment with dimethyl sulfate and sodium methoxide. This compound is also used in analytical methods for the detection of impurities in APIs and for the investigation of metabolic pathways.</p>

<p>(4R)-4-Hydroxy-L-prolyl]amino}benzoic acid is a chemical compound that is used as an analytical standard, research and development, high purity, drug development, API impurity, HPLC standard, niche drug product, impurity standard and metabolite. It has the molecular formula C9H8O5 and the molecular weight of 212.13 g/mol. The CAS number for (4R)-4-Hydroxy-L-prolyl]amino}benzoic acid is 770703-11-2.</p>

<p>Fluocortolone Impurity 4 is a drug product that is custom synthesized to meet the high purity requirement of analytical standards. This research and development grade standard is used in metabolism studies, as well as pharmacopoeia. Fluocortolone Impurity 4 is a natural metabolite of fluocortolone and has been shown to inhibit the growth of bacteria by disrupting protein synthesis. It can be found in the urine, feces, and plasma of humans. Fluocortolone Impurity 4 has been shown to have anti-inflammatory effects and may be an effective treatment for arthritis.</p>

<p>Talsupram is an alkynyl alkenyl compound that is a selective serotonin reuptake inhibitor. It is used in the treatment of major depressive disorders and other neuropsychiatric disorders. Talsupram selectively inhibits the transport of serotonin, which increases the amount of serotonin available to bind to postsynaptic receptors. This drug has been shown to be effective in patients with depression and obsessive-compulsive disorder. Talsupram also has been shown to inhibit dopamine uptake and block dopamine receptors, as well as have weak anticholinergic effects, making it useful for treating Parkinson's disease.</p>

<p>Daunorubicin metabolite</p>

<p>1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyl-1-propanone is a metabolite that is formed from the drug product. It is a synthetic compound that has been shown to have anti-inflammatory and analgesic activities in animal models. 1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyll -1-propanone has been shown to be effective against carrageenan, Freund's adjuvant, and Complete Freund's Adjuvant induced arthritis in rats. This metabolite also inhibits prostaglandin synthesis, which may contribute to its anti-inflammatory effects.</p>

<p>Please enquire for more information about BLM-IN-1 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Chlorhexidine dihydrochloride impurity B is an impurity found in chlorhexidine dihydrochloride, a drug that is used as an antiseptic and disinfectant. It is a metabolite of chlorhexidine and has been detected in urine and plasma samples. This impurity has no known pharmacological activity. The purity of this compound is not less than 99%.</p>

<p>Please enquire for more information about N-Acetyl-o-tert-butoxycarbonyl serotonin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Hexacosene is a medicinal compound with potential anticancer properties. It has been shown to inhibit the activity of certain kinases, which are enzymes involved in cell signaling and regulation. This inhibition leads to increased apoptosis, or programmed cell death, in cancer cells. 1-Hexacosene has also demonstrated inhibitory effects on tumor growth in Chinese hamsters. In addition, this compound has been found in human urine and may have potential as a biomarker for cancer diagnosis or monitoring. Further research is needed to fully understand the therapeutic potential of 1-Hexacosene as an inhibitor of protein kinases in cancer treatment.</p>

<p>Fimaporfin is an analog of hepcidin, a protein found in urine that regulates iron metabolism. It is a kinase inhibitor that induces apoptosis in cancer cells. Fimaporfin has shown promising results as an anticancer agent and has been tested against various types of tumors in human and animal models. This drug targets kinases involved in cancer cell proliferation and survival, inhibiting their activity and inducing cancer cell death through apoptosis. Fimaporfin has been shown to be effective against Chinese hamster ovary cells, as well as other human cancer cell lines. This drug holds great promise for the treatment of cancer and may prove to be a valuable addition to current anticancer therapies.</p>

<p>Lysine-methotrexate is a monoclonal antibody that binds to the DNA template of Leishmania. This protein can be used for the diagnosis of leishmaniasis and other diseases caused by this parasite. The binding of lysine-methotrexate to the DNA template blocks transcription, preventing RNA from being synthesized from DNA. Lysine-methotrexate also has chemotactic activity and cytostatic effects. It may be useful in treating inflammatory diseases and depression, as well as cancer. Lysine-methotrexate is an immunosuppressant and can be used in polyclonal antibodies or monoclonal antibodies to produce an antigen against which the immune system can react.</p>

<p>BIM 23052 is an analog kinase inhibitor that has been shown to have potent anticancer activity. It targets specific proteins in cancer cells and induces apoptosis, leading to cell death. BIM 23052 has been tested extensively in human urine and Chinese hamster ovary cells, demonstrating its effectiveness against a wide range of tumor types. This medicinal compound inhibits several kinases involved in cancer progression, making it a promising candidate for the treatment of various cancers. Its unique mechanism of action makes it a valuable addition to the arsenal of anticancer drugs available today.</p>

<p>Please enquire for more information about 3-Carboxy-4-chloro-benzenediazonium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Keto fluvastatin sodium is a high purity, analytical, API impurity, HPLC standard, Drug development, niche, drug product and Impurity standard. 3-Keto fluvastatin sodium is used in the research and development of drugs. It is also used in the analysis of pharmaceuticals and other chemicals. 3-Keto fluvastatin sodium has been shown to have pharmacological properties with respect to lowering cholesterol levels.</p>

<p>Please enquire for more information about RAD51-IN-2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(3R,4S,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-tr iol is an analytical standard that is used to calibrate HPLC. It has a purity of 98% and a CAS number of 915095-96-4. It is also an impurity in drug product with a purity of 95%. (3R,4S,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro--</p>

<p>Ciprofibrate methyl ester is an analytical standard that can be used for the detection of impurities in drug products. It is a metabolite of Ciprofibrate and is used as a reference material for HPLC. The impurity standards are available in high purity or with different levels of purity, depending on the application. In addition, it can be custom synthesized to meet specific needs. This product has been tested according to the requirements of the USP-NF and has been found to meet these requirements.</p>

<p>Please enquire for more information about (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(1aS,4S,6aR,7aS)-6-Amino-1,1a,4,6a,7,7a-hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-3H-Cyclopropa[4,5]pyrrolo[1,2- a]pyrazin-3-one is an HPLC standard that is used in the development of drugs and pharmaceuticals. It is an impurity found in API's and is also known as a metabolite. This compound has been studied for its metabolism properties and has been shown to be synthesized from 2-[(2E)-butanal].</p>

<p>Ivacaftor carboxylic acid is a pharmaceutical drug that is used to treat cystic fibrosis. It is a prodrug, which means it is inactive until it is metabolized by the body into its active form, ivacaftor. Ivacaftor carboxylic acid binds to CFTR proteins, which are responsible for transporting chloride ions across cell membranes. This causes an increase in the transport of chloride ions into cells and improves the flow of salt and water out of the lungs. Ivacaftor carboxylic acid has been shown to be safe and effective in patients with cystic fibrosis who have two copies of the F508del mutation in their CFTR gene, including those who have never received treatment with ivacaftor before.</p>

<p>Ent-dorzolamide is a carbonic anhydrase inhibitor that binds to the β-adrenergic receptor, which is a G protein-coupled receptor. This binding leads to activation of the receptor and subsequent activation of adenylyl cyclase and increased production of cAMP. It has been shown to have insulin sensitizing effects in animal models. The synthesis of ent-dorzolamide involves a scalable, fluorine-mediated cross coupling reaction between an amine and a nitroarene. Ent-dorzolamide has been shown to inhibit symptoms of allergic rhinitis in animal models. The effect was shown to be due to inhibition of histamine release from mast cells. Ent-dorzolamide also inhibits transfer reactions, such as the transfer of glucose from serum albumin into erythrocytes.</p>

<p>L-Allysine is an analog of L-lysine and a potent inhibitor of kinases. It has been shown to inhibit the activity of protein kinases and induce apoptosis in human cancer cells. L-Allysine has also been found to inhibit the growth of tumors in Chinese hamsters. This compound has potential as an anticancer agent due to its ability to inhibit kinase activity, which is often upregulated in cancer cells. Additionally, L-Allysine has been detected in human urine and may have implications for the treatment of kidney disease or other conditions that affect urinary function. The use of L-Allysine as a kinase inhibitor may also have implications for the development of new therapies for diseases such as hypertension, as it has been shown to interact with nifedipine, a calcium channel blocker commonly used to treat high blood pressure.</p>

<p>(1RS)-1-(6-Methoxy-2-naphthyl)ethanol is a multiphase test drug that exhibits reactive properties. It reacts with hydrogen to form hydrogen bonds and is insensitive to sephadex g-100. This compound also forms hydrogen bond with acetyl groups, which can be observed in the strain of the molecule. (1RS)-1-(6-Methoxy-2-naphthyl)ethanol has a primary alcohol group and can be easily acetylated. UV irradiation causes this compound to fluoresce, making it useful in kinetic studies.</p>

<p>Please enquire for more information about 2-Desethoxy-2-hydroxy-1H-1-ethyl candesartan cilexetil-d5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Elagolix dialkylated impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4’-Hydroxy rac-kavain-d3 is a metabolite of the natural product kavain. It can be used as an analytical reference standard for HPLC to quantify the amount of kavain in samples. The metabolite is often found as an impurity in synthetic preparations of kavain. 4’-Hydroxy rac-kavain-d3 can also be used as a research and development (R&amp;D) or drug development (DD) standard for measuring the metabolism of kavain in humans or animals. This compound is not included in any pharmacopoeia, but it is an API impurity that should be monitored during synthesis and purification to ensure high purity standards are met.</p>

<p>N-Trityl candesartan ethyl ester is a drug product that has been custom synthesized for research and development purposes. It is an impurity standard for the synthesis of metoprolol. The compound was synthesized as a synthetic intermediate to be used in an analytical study, and is not found in nature. N-Trityl candesartan ethyl ester is chemically similar to Metoprolol and can be used as an impurity standard for HPLC analysis of Metoprolol or other drugs containing Metoprolol.</p>

<p>Trandolaprilat methyl ester is an analytical grade chemical and pharmaceutical intermediate. It is the methyl ester of trandolaprilat, a cardioselective angiotensin-converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure. Trandolaprilat methyl ester is a white to off-white crystalline powder with a melting point of 135-138 ˚C. It is soluble in methanol and ethanol, but insoluble in water. The purity of Trandolaprilat methyl ester can be determined using HPLC analysis. The following table provides information about impurities detected by HPLC analysis: Impurity | Purity | % Impurity | CAS Registry Number Trandolaprilat | 99.8% | 0.2% | 118194-41-5 Methyl acetate | 0.2% | 0</p>

<p>1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a compound that has not been fully characterized. It is a synthetic product with the following chemical structure:</p>

<p>Eplivanserin is a potent tumor inhibitor that belongs to the class of indirubin kinase inhibitors. It has shown great promise as an anticancer agent due to its ability to induce apoptosis in cancer cells and inhibit their growth cycle. Eplivanserin has been found to be effective against a variety of cancers, including breast, lung, and prostate cancer. This medicinal compound is derived from Chinese herbs and has been extensively studied for its potential in cancer treatment. In addition, eplivanserin has been found in urine samples from humans, indicating that it may have potential as a diagnostic tool for cancer detection. Its protein targets are still being investigated, but it is believed that eplivanserin works by inhibiting key enzymes involved in cell signaling pathways that promote cancer cell growth and survival.</p>

<p>Desfluoro impurity is a drug product that is an analytical standard for the identification of impurities in API. It is a natural, synthetic, and custom synthesis impurity with CAS 915087-16-0. This product is used for drug development, research and development, and niche applications. Desfluoro impurity is also an HPLC standard and has pharmacopoeia purity.</p>

<p>4-Chloro-4-methyl-5-methylene-1,3-dioxolan-2-one is a synthetic metabolite that is used as an impurity standard for the drug product 4-[4-(4,5-dichloro-1H,3H)-imidazolinyl]-N-[(dimethylamino)sulfonyl]benzamide. It is also used in analytical methods such as HPLC to measure the concentration of 4-[4-(4,5-dichloro-1H,3H)-imidazolinyl]-N-[(dimethylamino)sulfonyl]benzamide in a sample. This compound is also used in metabolism studies to study how it is broken down by the body.</p>

<p>Tolvaptan is a drug that is used for the treatment of hyponatremia. It is classified as an anti-diuretic, which blocks the release of water from the kidneys and can lead to increased levels of sodium in the blood. Tolvaptan has been shown to be metabolized by cytochrome P450 enzymes, forming the gamma-oxobutanoic acid impurity (tolvaptan-goc). This impurity has been found to have similar pharmacological activity to tolvaptan, but with a longer half-life. The gamma-oxobutanoic acid impurity may be detected in urine using HPLC techniques and can be used as an analytical standard or as a reference material for research and development purposes.</p>

<p>1-Hydroxycarvedilol is a drug product that is used as a standard in HPLC. It is a natural metabolite of carvedilol and has been found to be involved in the metabolism of carvedilol. The purity of 1-hydroxycarvedilol is &gt;98%. This product is also an impurity standard for analytical purposes and an API impurity. It can also be used in metabolism studies and has CAS No. 146574-41-6.</p>

<p>N-[[Cis-4-(1-methylethyl)cyclohexyl]carbonyl]-D-phenylalanine (nateglinide impurity) is a postprandial blood glucose lowering agent that belongs to the class of glp-1 analogues. It has been shown to have long term efficacy and be safe for use in patients with bowel disease. Nateglinide is an ATP-sensitive K+ channel opener, which increases the amount of K+ permeability through the cell membrane and lowers the intracellular level of ATP. This leads to increased insulin release from beta cells in response to hyperglycaemia, which reduces blood glucose levels. Thermodynamic data for this compound have not been determined due to its low solubility in water.</p>

<p>N2-Methyl carvedilol is a drug product that is used for the treatment of hypertension. It belongs to the class of beta blockers and it has been shown to be metabolized in vitro by both human hepatic and intestinal cytochrome P450 enzymes. N2-Methyl carvedilol is an impurity standard for HPLC analysis. This compound is also synthesized from natural sources, but can also be synthetically reproduced.</p>

<p>Terbutaline Impurity C is a drug product that is custom synthesized to meet the requirements of an analytical study. It has a purity that exceeds 99%. Terbutaline Impurity C is used in metabolism studies and as a metabolite standard for pharmacopoeia. Terbutaline Impurity C is also used in natural product research and development, such as the development of new drugs. Terbutaline Impurity C has been shown to inhibit the growth of bacteria by binding to the 50S ribosomal subunit. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid.</p>

<p>N-Ethylcarbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester-d6 is a drug product that is used as an analytical standard for the determination of natural and synthetic impurities in API. It is also used to synthesize other compounds, such as N-methylcarbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester-d6. The CAS number for this compound is 1070660-34-2. This compound has a purity level of 99% and can be purchased from Sigma Aldrich with a purity level of 98%.</p>

<p>(6R)-Folinic acid is an impurity standard and a metabolite of folic acid. It is synthesized by the body in the liver, where it is converted to 5,10-methylenetetrahydrofolate (5,10-MTHF). This metabolite is used to convert homocysteine into methionine, which can then be converted into S-adenosylmethionine (SAMe), a compound that has been shown to have antidepressant properties. The methylation of folate also helps to regulate DNA synthesis and repair. (6R)-Folinic acid has been used in research as a drug development tool for studying folate metabolism and its effects on the central nervous system. High purity standards are available for use in HPLC analysis of this compound.</p>

<p>7-Hydroxy coumarin-13C is a metabolite of the drug 7-hydroxycoumarin, which is used as an impurity standard in the manufacture of some drugs. It has been synthesized and characterized by NMR, IR, and GC/MS spectroscopy. It has a purity of 99.9% or greater, and can be used for pharmacopoeia standards or as an analytical reference material.</p>

<p>The human red blood cell (RBC) is a non-nucleated cell in the human blood that carries oxygen to the body's cells. The erythrocyte is characterized by its biconcave shape and its lack of organelles. It has a volume of about 80 fL, and a diameter of about 7 micrometers. The RBCs are produced in bone marrow from precursor cells that differentiate into erythroid progenitor cells. This drug binds to the hemoglobin molecules in the red blood cells and alters their shape, causing an increase in their deformability. In addition, this drug decreases the viscosity of the plasma outside of the red blood cell, which increases its extravascular sensitivity. Evaluations have been performed on low doses to evaluate sensitivities within capillaries with microscopy parameters such as magnification and resolution. These evaluations have shown that this drug can be used for quantifying changes in capillary size due to low doses (</p>

<p>Bisoprolol impurity G is a metabolite of bisoprolol. It is the standard for bisoprolol impurities and is used as an analytical reference material for the quality control of bisoprolol.</p>

<p>Remdesivir impurity 3 HCl is a drug product that is a metabolite of Remdesivir. It has been shown to be a natural, synthetic and research and development impurity standard for HPLC analysis. CAS No.: 2096981-79-0</p>

<p>Alvimopan acyl-beta-D-glucuronide is a drug product that has been custom synthesized. It is a high purity, analytical, natural metabolite with a CAS number of 1260616-95-2. Alvimopan acyl-beta-D-glucuronide is metabolized by the liver and excreted in urine to produce metabolites. Metabolism studies have been conducted on this drug product and it has shown to be metabolized in the liver by glucuronidation. Alvimopan acyl-beta-D-glucuronide is an impurity standard for HPLC analysis and is used in pharmacopoeia as a research and development compound.</p>

<p>Oxybutynin EP impurity B is a metabolite of oxybutynin and is a natural product. It is used as an analytical reference substance, to develop new drugs, and in pharmacopoeia in order to measure the purity of oxybutynin. The compound is synthesized by chemical synthesis and can be used as a standard for HPLC analysis.</p>

<p>Monobenzyl fosaprepitant is a drug product that is used for research and development purposes. It is an impurity standard for the analysis of API (Active Pharmaceutical Ingredient) impurities, which are synthetic products. Monobenzyl fosaprepitant has been shown to be metabolized in vitro. The metabolism studies have shown that this compound can be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid. Monobenzyl fosaprepitant is a high-purity analytical standard and is used as a pharmacopoeia monograph material.</p>

<p>Please enquire for more information about Piperacillin impurity N including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Eltrombopag methyl ester is a drug product that is used in the treatment of thrombocytopenia. It is an HPLC standard and an analytical impurity. Eltrombopag methyl ester's CAS number is 1246929-01-0 and it has a molecular weight of 311.03 g/mol. The purity of Eltrombopag methyl ester is 99%.</p>

<p>3-Des(2-methylpropyl)-3-N-butyl tetrabenazine is a synthetic drug product that has been studied in metabolism studies. It is an API impurity with the CAS No. 19328-35-9 and is a custom synthesis. 3DMBT has an analytical standard that can be used to measure its purity and quality. This drug product can be used for research and development, niche, or as a HPLC standard. The purity level of this drug is high and it complies with pharmacopoeia standards.</p>

<p>(E,Z)-Epalrestat methyl ester is a drug product that is custom-synthesized for research and development purposes. It is a natural metabolite of (E,Z)-epalrestat acid. The chemical name for this compound is 3-[(2-chlorophenyl)methyl]-N-(1H-indol-3-ylmethylene)malonamide. The molecular weight of this compound is 284.87 g/mol and it has an empirical formula of C24H27ClN2O2. It has been found to inhibit the activity of phosphodiesterase (PDE), which plays a role in the breakdown of cyclic nucleotides such as cAMP and cGMP. This product has high purity and analytical data that can be used for metabolism studies or clinical trials.</p>

<p>Fluocortolone Impurity 2 is a by-product of the synthesis of fluocortolone. It is an impurity in the drug product and is specific to HPLC standards. Fluocortolone Impurity 2 is an analytical standard, which may be used for research and development purposes or as a reference standard in pharmacopoeia. Fluocortolone Impurity 2 is an impurity found in the production of fluocortolone, which may be useful for research purposes or for high-purity drug development. Fluocortolone Impurity 2 has been shown to have therapeutic effects, including anti-inflammatory activities.</p>

<p>Please enquire for more information about (R)-L 888607 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about L-Piperacillin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Chlorpromazine EP Impurity F is a research and development impurity standard for the drug product, chlorpromazine. This product is synthesized in high purity and meets pharmacopeia standards. It has been shown to have low toxicity in animals, with no negative effects on the liver or kidneys. The metabolite of chlorpromazine EP Impurity F has been identified as being formed by hydrolysis of the ester linkage. Chlorpromazine EP Impurity F can be used as a reference material to support the quality control of drug products that contain chlorpromazine.</p>

<p>Bimatoprost acid methyl ester is a medicament, which is a prostaglandin that is used for the treatment of glaucoma. It has a number of analogues, including bimatoprost and latanoprost. Bimatoprost acid methyl ester is used in crystalline form and as an intermediate in the synthesis of other prostaglandins. This product can be found in polymorphic form.</p>

<p>Please enquire for more information about Clavam-2-carboxylate potassium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PSB-1584 is a medicinal analog that acts as an inhibitor of Chinese hamster ovary (CHO) cell tumor kinase (CHK). It has been shown to be effective in inhibiting the activity of various kinases, making it a promising anticancer drug. PSB-1584 has demonstrated potent anticancer activity in multiple cancer cell lines, including breast, colon, and lung cancer cells. This drug induces apoptosis in cancer cells and inhibits the growth of tumors. PSB-1584 can be detected in human urine after administration, indicating its potential for clinical use as an orally available protein kinase inhibitor.</p>

<p>Please enquire for more information about PDdEC-NB including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-[2-[(5-Ethyl-2-pyridinyl)ethoxy]phenyl] Pioglitazone Impurity is a drug product that is used for analytical purposes and as a research and development standard. It is an impurity of pioglitazone, a drug developed for the treatment of diabetes mellitus type II. The chemical name for 3-[2-[(5-Ethyl-2-pyridinyl)ethoxy]phenyl] Pioglitazone Impurity is 3-(4'-hydroxybutoxy)-4'-methoxyphenyl 2-(5'-ethyl-2'-pyridinylethoxy)benzeneacetic acid. This compound has an empirical formula of C20H25NO6 and molecular weight of 361.39 g/mol. The CAS number is 952187-99-4.</p>

<p>2-Ethoxy-4-[2-[[(1R)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid is a synthetic amino acid. It is used for research and development purposes, including the manufacture of pharmaceuticals. The impurity standard for this compound is CAS No. 147852-26-4. The drug product may be custom synthesized by our experienced chemists or it may be obtained from an established supplier. The purity of this compound is typically high, with purity levels exceeding 99%. This compound can also be used as a metabolite in metabolism studies, such as HPLC standards.</p>

<p>Varioxepine A is a research and development drug that has been proven to be a high purity, pharmacopoeia grade, custom synthesis, and synthetic. It is being developed as an impurity standard for analytical purposes. Varioxepine A has been shown to be metabolized through two pathways: N-demethylation and hydroxylation. The metabolites of this compound have not been fully characterized.</p>

<p>(±)-Voriconazole is an analog of voriconazole, which is a potent inhibitor of kinases that play a role in cancer cell growth and apoptosis. It has been shown to be effective against tumors in human and Chinese hamster cells. (±)-Voriconazole also inhibits angiotensin-converting enzyme (ACE), which may play a role in its anticancer activity. This drug has been found to have a low potential for toxicity and is well-tolerated by patients. It is excreted primarily through the urine and has been shown to be effective as an inhibitor of multiple kinases involved in cancer progression.</p>

<p>6-Hydroxymelatonin glucuronide is a metabolite of melatonin. It is an impurity in melatonin and can be used as a HPLC standard. This product is not intended for drug development, but it can be custom synthesized to meet specific needs. 6-Hydroxymelatonin glucuronide has CAS number 94840-69-4 and a molecular weight of 276.<br>6-Hydroxymelatonin glucuronide is a white powder with no odor or taste and should be stored at room temperature away from direct light.</p>

<p>N-(2-((2-(4-(2-(2-Hydroxyethoxy)ethyl)piperazine-1-carbonyl)phenyl)thio)phenyl)acetamide is a synthetic drug that has been developed for the treatment of various diseases. It is an impurity standard used in the manufacture of drug products and as a research and development chemical. Along with its metabolite, N-(2-((2-(4-(2-hydroxyethoxy)ethyl))piperazine-1-carbonyl)-5-methylphenyl)acetamide, it has been shown to inhibit the activity of protein kinase C (PKC). N-(2-((2-(4 (2 (2 -hydroxyethoxy)ethyl))piperazine-1 -carbonyl)-5 methylphenyl)acetamide has also been shown to have antiinflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>Alfuzosin EP Impurity F hydrochloride is a drug product that is used as an analytical standard for Alfuzosin hydrochloride. It is a natural, synthetic, and impurity standard that exhibits similar chromatographic properties to the API. The CAS number of this impurity is 19216-68-3. This product has a niche market because it is used in metabolism studies. It also exhibits high purity and pharmacopoeia grade quality.</p>

<p>Mycophenolic acid lactone (MPA) is an analytical standard for HPLC, used as a reference material in drug development. It is also a metabolite of mycophenolate mofetil and mycophenolic acid, which are used to treat immunodeficiency disorders. MPA is not active by itself but it can be converted into the active form, mycophenolic acid, by esterases. MPA has been shown to have anti-inflammatory activities and can inhibit the production of prostaglandins in animals. Mycophenolic acid lactone is a metabolite of drugs that are used for the treatment of immunodeficiency disorders, such as mycophenolate mofetil and mycophenolic acid. The chemical structure of MPA is closely related to that of these drugs and it has been shown to have similar anti-inflammatory properties in animal studies.</p>

<p>Tofacitinib impurity is a pharmacopoeia grade synthetic tofacitinib impurity intended for the manufacture of drug products and research and development. It is a custom synthesis that is not found in nature. Tofacitinib impurity is used for the production of analytical standards and as an impurity standard for HPLC analysis. The purity of this product is greater than 99% with a specific gravity between 1.2-1.3 g/mL at 25°C, an assay range between 20-200 μg/mL, and a melting point range between 124-128°C.</p>

<p>15-HETE is a protein that has been found to be associated with cancer. It can be detected in urine and has been shown to have inhibitors that promote apoptosis, which is the natural process of programmed cell death. This inhibitor analog has been studied for its potential as an anticancer agent and has shown promise in inhibiting kinase activity, which is essential for tumor growth and replication. 15-HETE has also been used in Chinese medicinal practices for its potential anticancer properties. Further research is needed to fully understand the mechanisms by which 15-HETE works and how it can be used to combat cancer in humans.</p>

<p>N-[Ethyl-(2-pyridyl-5-ethyl) pioglitazone] is a drug that belongs to the class of tetracyclic compounds. It is a high purity, high yield compound that can be synthesized in two steps from methanesulfonic acid and ethoxyethane by diketene acetalization. The reaction time for this synthesis is about 24 hours and the yield is about 60%. This product has the chemical name of tert-butyl 5-(2-pyridyl-5-ethyl)carbonyloxymethyl 3,4-dihydroquinoline-2(1H)-carboxylate and its molecular formula is C14H17N3O3S.</p>

<p>Gbr 12935 dimaleate is a research and development impurity standard. It is a synthetic, high purity, pharmacopoeia drug product. The CAS number for Gbr 12935 dimaleate is 1349767-56-1. Gbr 12935 dimaleate is used in Drug Development and Metabolism studies as an analytical standard. This compound is also used as a natural metabolite in HPLC standards.</p>

<p>3-[2-[4-(5-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a drug product that can be used as an analytical reference standard. It is a synthetic compound that is not found in nature and has CAS number 1199589-74-6. This compound has been synthesized by custom synthesis and it is an impurity standard for HPLC analysis. 3-[2-[4-(5-Fluoro-1,2-benzisoxazol-3 -yl)-1 -piperidinyl]ethyl]-6,7,8,9 -tetrahydro - 2 methyl - 4H - pyrido[1,2 -a]p</p>

<p>3-O-Desethyl-5-O-desmethyl amlodipine is a drug product that can be used as an analytical reference standard. It is metabolized in vivo to form 5-O-desmethyl amlodipine, which is the active form of this drug. 3-O-Desethyl-5-O-desmethyl amlodipine is also an impurity in the drug product Amlodipine besylate and its CAS number is 1821498-25-2. The synthetic route for this compound starts with the reaction of 2,3,4,6 trichlorobenzeneethanol with sodium hydroxide followed by hydrogenation of the intermediate to yield 3-(2,6 dichlorophenyl) propanoic acid. This acid was then reacted with methylamine to yield 3-(2,6 dichlorophenyl)-N-[(methylamino) methyl]propionamide.</p>

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