APIs for research and impurities

<p>Please enquire for more information about Fenirofibrate acyl-β-D-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Methyl-3,4-dimethoxy pyridine hydrochloride is an analytical standard that is used as a reference compound in the pharmaceutical industry to identify impurities in drug products. It also has a niche use as an API impurity and HPLC standard. 2-Methyl-3,4-dimethoxy pyridine hydrochloride is used as an intermediate for the synthesis of other drugs, including benzodiazepines and beta blockers. It is also used in research and development for its high purity. This chemical is natural or synthetic in origin but can be custom synthesized to meet specific requirements. 2-Methyl-3,4-dimethoxy pyridine hydrochloride also has CAS number 1210824-88-6.</p>

<p>Cetirizine amide dihydrochloride is a drug product that has been custom synthesized for research and development. It is a high purity, analytical grade material that is natural and synthetic in origin. Cetirizine amide dihydrochloride's CAS number is 200707-85-3. The impurity standard for this material is HPLC grade. This drug product can be found on the United States Pharmacopoeia (USP) and the European Pharmacopoeia (EP). Cetirizine amide dihydrochloride has been used in metabolism studies and as a pharmacopoeia reference standard.</p>

<p>(2S,2R,Trans)-saxagliptin is an analytical standard that is used in the development of drug products. This compound has a purity of greater than 98% and is a metabolite of saxagliptin. It has been shown to inhibit the activity of DPP-IV (dipeptidyl peptidase-4), which is an enzyme that degrades certain hormones such as glucagon-like peptide 1 (GLP-1). The product is manufactured by natural means and does not have any impurities. It does not have any major side effects and is not associated with weight gain.</p>

<p>Please enquire for more information about 6-Amino-N-(2,6-dimethylphenyl)hexanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Desethylene posaconazole N,N’-diformyl is an analog of posaconazole that has been shown to have potential as an anticancer agent. It induces apoptosis in cancer cells by inhibiting various kinases, including cyclin-dependent kinases. Desethylene posaconazole N,N’-diformyl has been detected in human urine and may have potential as a diagnostic marker for cancer. This compound has also shown promising results in inhibiting the growth of human tumor cells and Chinese hamster ovary cells. As a protein kinase inhibitor, Desethylene posaconazole N,N’-diformyl has the potential to be used in the treatment of various types of cancer.</p>

<p>Please enquire for more information about (E)-2-Cyanoethyl 3-aminobut-2-enoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ly 2389575 hydrochloride is a drug product for the treatment of rheumatoid arthritis, psoriatic arthritis, and plaque psoriasis. It is synthesized in a natural manner from the fermentation of Streptomyces lavendulae. The compound has been shown to be metabolized through a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Ly 2389575 hydrochloride also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>

<p>(R)-N-Methyl-laudanosine iodide is an impurity that has been reported in the product of a custom synthesis. This impurity can be used as an analytical standard or as a reference material for HPLC analysis. It is also used to study the metabolism of drugs, including how they are processed by the body and how it may affect their pharmacological activity. (R)-N-Methyl-laudanosine iodide is synthesized synthetically and can be customized to meet your needs.</p>

<p>Hexahydrophenyl cinacalcet hydrochloride (HPC) is a synthetic compound that is used as an impurity standard in the manufacture of other drugs. It is also used in research and development for the purpose of evaluating drug products. HPC is a metabolite of cinacalcet, which is a drug for the treatment of secondary hyperparathyroidism, particularly in patients with chronic renal failure. HPC has been shown to inhibit bone resorption, which may be due to its effects on calcium metabolism. HPC has also been shown to have anti-inflammatory properties that may be due to its effects on prostaglandins synthesis.</p>

<p>Pelitinib-d6 is an anticancer drug that inhibits the activity of protein kinases, which are enzymes involved in cell cycle regulation and apoptosis. This drug has been shown to be effective against various types of cancer cells, including those found in human tumors and Chinese hamster ovary cells. Pelitinib-d6 acts as a potent inhibitor of the epidermal growth factor receptor (EGFR) and other related receptors, which play a key role in cancer cell growth and proliferation. This drug has also been found to inhibit heparin-induced platelet aggregation, making it potentially useful for preventing blood clots associated with cancer. Pelitinib-d6 is a deuterated analog of pelitinib, which means that it contains six deuterium atoms instead of hydrogen atoms. This modification can enhance the stability and pharmacokinetics of the drug, making it more effective as a medicinal agent.</p>

<p>Trandolaprilat diketopiperazine is an analog of trandolapril, a medication used to treat high blood pressure. Trandolaprilat diketopiperazine has been found to have potential anticancer properties by acting as an inhibitor of several kinases involved in cancer cell growth and apoptosis. This compound has been shown to inhibit the growth of human cancer cells in vitro and in vivo, making it a promising candidate for further research into its potential as an anticancer agent. Trandolaprilat diketopiperazine can be detected in urine after administration, indicating that it may be suitable for use as a medicinal compound. Its ability to inhibit protein kinases makes it a valuable tool for studying the role of kinases in cancer progression and identifying new targets for anticancer therapies.</p>

<p>Pseudomonic acid B is a metabolite of pseudomonic acid A and is used as an impurity standard for the pharmacopoeia. The purity of this product is high, with a minimum of 98% pseudomonic acid B. This substance has been synthesized from the natural sources pseudomonic acid A and pseudomonic acid C. Pseudomonic acid B is also a metabolite of pseudomonic acid A and has been used to study the metabolism of pseudomonic acids.</p>

<p>Valdecoxib impurity I is a synthetic compound that is used as an impurity standard for the drug product Valdecoxib. It has a CAS number of 1373038-59-5 and is used in HPLC analysis to detect the presence of metabolites. Valdecoxib impurity I has been shown to be a metabolite of Valdecoxib, but the metabolic pathway has not been elucidated.</p>

<p>Please enquire for more information about 7-Chloro-3-(piperazin-1-yl)benzol[D]isothiazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The ethylene terephthalate cyclic pentamer is a polyester that is used in the manufacture of polyester fibers and polyester films. It is extracted from the raw material, which is a mixture of dimethyl terephthalate, ethylene glycol, and 1,4-butanediol. The extruder heats the raw material to 240°C in order to convert it into its liquid form. The crystallization process takes place at room temperature and produces a white solid product called oligomer. Extraction removes impurities from the oligomer by washing it with water. Linear polyester is obtained by heating the purified oligomer at 260°C for 40 minutes, while extruded polyester undergoes a heat treatment of 230°C for 20 minutes. Extrusion produces pellets that are then processed into filaments or sheets.</p>

<p>This compound is a research and development impurity standard with a custom synthesis. It is synthesized in the lab using high purity methods to produce an API impurity for drug product. The compound is available in high purity, pharmacopoeia, and analytical grade. This compound is used as an analytical reference standard. Metabolites of this compound have been studied to determine its metabolism pathway.</p>

<p>1-Isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile is a fluorescent probe that can be used for the detection of drugs in biological samples. It has been shown to have a high fluorescence intensity and low detection sensitivity, making it suitable for use as a probe for detecting drugs with low concentrations. This probe can also be used to study drug interactions and its concentration–time curve in humans. The drug transporter P-glycoprotein (Pgp) is inhibited by verapamil, which could explain the increase in 1-isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile's detection sensitivity.</p>

<p>Please enquire for more information about Lercanidipine-D impurity 6 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Losartan related compound D is an antihypertensive agent that has been shown to reduce blood pressure in experimental animals. It is a prodrug that is hydrolyzed by esterases to losartan, its active form. Losartan related compound D has been shown to significantly improve the function of ventricular cells in rats with hypertension. The mechanism for this effect may be due to the ability of losartan related compound D to inhibit the production of inflammatory mediators and decrease the reactivity of vascular endothelial cells.<br>Losartan related compound D has not been extensively studied in humans; therefore, it is difficult to predict its effectiveness as a treatment for diseases such as heart failure or stroke.</p>

<p>Des-chloromeclozine-d9 is a research and development impurity standard. It is used as an impurity in the synthesis of meclozine, a drug product. This compound is synthesized using the organic chemistry laboratory technique called custom synthesis. The purity of this compound is high and it meets the requirements of pharmacopoeia standards for analytical use. Des-chloromeclozine-d9 has been found to be a metabolite of meclozine and may have some niche applications for metabolism studies. This synthetic compound has CAS number 16896-82-5.</p>

<p>Please enquire for more information about N-[2-[(4-Chlorophenyl)thio]phenyl]-carbamic acid phenyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Thalrugosaminine is an ethanolic extract of the bark and roots of the Indian plant Thalrugosia jatrorrhizina. It has been shown to have potent antibacterial activity against Staphylococcus aureus, and an in vitro study showed it to be effective against Mycobacterium tuberculosis. Thalrugosaminine has been used as a herbal remedy for infectious diseases such as bovine mastitis and human disorders such as thaligosis. It has also been shown to have hypotensive effects in animal studies.</p>

<p>Ethyl 6-[4-[(5-chloro-1-oxopentyl)amino]phenyl]-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is a chemical compound with various applications. It is soluble in methanol and has been found to interact with peptidoglycan, cellulose, and other substances. This compound has shown potential anticoagulation properties and has been studied for its effects on blonanserin, etoricoxib, 27-hydroxycholesterol, tenofovir, proton, famotidine, dimethyl fumarate, calpain, dimethyl sulfoxide, and reactive agents. Further research is needed to fully understand the potential applications of this compound and its interactions with different substances.</p>

<p>O-Desethyl Dapagliflozin is a white powder that is a synthetic drug product. It is an impurity standard that can be used in the synthesis of dapagliflozin. O-Desethyl Dapagliflozin is also a high purity, pharmacopoeia grade drug product. This compound has been shown to be a metabolite of dapagliflozin and has been used for metabolism studies. It has been found to have niche applications in analytical chemistry and natural products research.</p>

<p>5-Oxo pitavastatin is a research and development drug product that is synthesized by custom synthesis. It is an impurity standard that is used as a reference in the analysis of pharmaceuticals and metabolites. The purity of this compound is over 99% with no detectable heavy metals, solvents, or other impurities. This product can be found in the pharmacopoeia, which lists it as an analytical reagent. 5-Oxo pitavastatin is used to develop drugs for niche markets and can be used to study metabolism.</p>

<p>Dihydrocephalomannine is a natural product that is used as a reagent in the synthesis of other molecules. It can be found in plants such as Taxus brevifolia, which contains the molecule taxol. Dihydrocephalomannine is synthesized by benzoylation and hydroxylation of dihydrobenzofuran. The molecule has been shown to have cytotoxic activity against human ovarian cancer cells, but its mechanism of action is not yet known.</p>

<p>Alpha-amino-4-octylbenzenebutanoic acid is an impurity standard for pharmacopoeia and drug development. It is a synthetic compound that has been shown to be a metabolite of the muscle relaxant succinylcholine. Alpha-amino-4-octylbenzenebutanoic acid is a high purity, custom synthesis material and can be used as a reference or calibration standard in analytical techniques such as HPLC.</p>

<p>2,3',5,5'-Tetrachlorobiphenyl is an analog that has shown potential in the development of anticancer agents. Studies have shown that it can inhibit the growth of tumor cells and induce apoptosis in human cancer cell lines. This compound has also been found to increase testosterone levels in male rats. Additionally, 2,3',5,5'-Tetrachlorobiphenyl has been studied as a potential inhibitor of kinases involved in cancer progression. Octreotide, a synthetic octapeptide analogue of somatostatin, has been shown to enhance the antitumor effects of this compound in Chinese hamster ovary cells. This compound may have potential as a therapeutic agent for the treatment of various types of cancer.</p>

<p>(2R)-2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-isopropylpentanenitrile hydrochloride (ZD4054) is a drug that has been shown to be sensitive to the efflux pump in Escherichia coli. It is also able to inhibit multidrug resistance in nematodes and cross-resistance in humans. ZD4054 inhibits multidrug resistance by inhibiting the efflux of drugs from cells. This prevents the development of resistance to antibiotics and other drugs. The mechanism of action for this drug is unknown, but it may affect chloride channels that are found on the cell membrane. ZD4054 has also been shown to be effective against C.elegans and Drosophila melanogaster, two species commonly used for research purposes.</p>

<p>3-Ethyl-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one is a research and development impurity standard. It is used as a pharmacopoeia and drug product impurity in the manufacture of pharmaceuticals. 3-Ethyl-2-methyl-6,7,8,9-tetrahydro-4H pyrido[1,2 a]pyrimidin 4 one is used in synthetic organic chemistry for the production of drugs. This compound is also used for metabolism studies such as HPLC standards.</p>

<p>Melatonin methoxy-d3 is a synthetic melatonin metabolite that is used as an impurity standard in the manufacture of drug products. It is also used as a research and development intermediate, a custom synthesis, or a raw material in the production of other drugs. Melatonin methoxy-d3 has CAS Number 60418-64-6 and its chemical name is 3-[2-(Methoxymethyl)benzofuran-5-yl]oxyindole. Melatonin methoxy-d3 is a synthetic drug product with high purity and pharmacopoeia grade. It has been shown to be effective in metabolism studies and to have niche applications for analytical work.</p>

<p>11-Hydroxyasenapine is a drug that has been developed for the treatment of schizophrenia and Parkinson's disease. It is metabolized to 11-hydroxysenapine, which has an affinity for dopamine receptors. It is a high purity API with a purity of 98.6%. This product is available as an HPLC standard or impurity standard.</p>

<p>Diltiazem EP Impurity H is a metabolite of diltiazem that is used as an impurity standard for the drug product. Diltiazem EP Impurity H has a purity level of 99% and is soluble in water. It is synthesized by reacting diltiazem with nitric acid, then hydrolyzing the product to form the desired compound. Diltiazem EP Impurity H can be used as an analytical reference material or a pharmacopoeia for HPLC standards.<br>Diltiazem EP Impurity H is a metabolite of diltiazem that is used as an impurity standard for the drug product. Diltiazem EP Impurity H has a purity level of 99% and is soluble in water. It is synthesized by reacting diltiazem with nitric acid, then hydrolyzing the product to form the desired compound. Diltiazem EP Impurity H can be used as an analytical reference material</p>

<p>JNJ-55308942 is a human Chinese nalbuphine analog that has been found to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in cancer cell growth and survival. JNJ-55308942 induces apoptosis, or programmed cell death, in tumor cells, making it a promising candidate for the treatment of various types of cancer. This inhibitor has shown to be effective against gastrin-induced proliferation of cancer cells and can be detected in urine after administration. With its potent anticancer activity, JNJ-55308942 holds great potential as a therapeutic agent for cancer treatment.</p>

<p>Preterramide C is a drug that belongs to the class of drugs known as aminopyridines. It is a metabolite of preterramide A and has been used as an analytical reference standard for HPLC. This product is available in the form of a pure white crystalline powder with a purity greater than 98%. It has been shown to be an impurity in drug products and can be used as an impurity standard, as well as being synthesized by natural or synthetic means.</p>

<p>Please enquire for more information about Tadalafil spiro-urethane impurity (EP impurity F) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Methyl-3-[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide is a synthetic compound that has been used as an impurity standard to determine the purity of drugs. It is also used in research and development, drug product, and custom synthesis. 4-Methyl-3-[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide has a CAS number of 851137-91-2 and is on the list of pharmacopoeias. This compound is not found in nature, but it can be synthesized in the laboratory. Metabolism studies have been conducted for this drug to identify its metabolites, which can be determined through HPLC analysis.</p>

<p>Propoxyphenyl homohydroxysildenafil is a preparative mass spectrometric analysis of the metabolite of sildenafil, which is a phosphodiesterase type 5 inhibitor. It has been shown to increase the flow rate in rats with an experimental pulmonary hypertension. The product ions of propoxyphenyl homohydroxysildenafil are m/z 409.3, 417.2, and 419.2, and its pharmacological study has been conducted on tadalafil and isobutyl.</p>

<p>Please enquire for more information about Des(methylpiperazinyl) imatinib dimer piperazinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>NPS-ALX-4A is a drug, which has been shown to have cognition-enhancing effects in mice. It is a 5-HT6 receptor antagonist and can be used as an animal model for human cognitive disorders. NPS-ALX-4A was administered orally to control mice and the animals were tested for learning and memory. The study showed that NPS-ALX-4A improved spatial memory in the mouse model. This drug has not been tested on humans, but it has shown cognitive benefits in the mouse model with no significant side effects.</p>

<p>(3α)-Allopregnanolone sulfate is a medicinal compound with potential anticancer properties. It is an analog of the natural hormone allopregnanolone and has been shown to inhibit kinases involved in cancer cell proliferation and survival. This compound induces apoptosis, or programmed cell death, in cancer cells by targeting proteins that regulate cell growth and division. (3α)-Allopregnanolone sulfate has been studied as a potential inhibitor of tumor growth in human cancer cells and has shown promising results. It can be detected in urine samples and has also been used in Chinese traditional medicine for its medicinal properties.</p>

<p>Cefixime EP Impurity C disodium is an impurity in the drug Cefixime EP. It is a by-product of the synthesis process, which can be removed by a purification process. This product is an analytical standard and is used for qualitative analysis in HPLC. It is also used as a research and development standard for drug development. This product has been classified as a niche impurity since it only occurs at trace levels in the drug product, but it may have pharmacological relevance to some patients. This impurity can be synthesized from natural or synthetic sources and is available for custom synthesis to meet specific customer needs.</p>

<p>Riboflavin 3',4'-diphosphate is a crystalline powder that has an analytical purity of 99.9%. This compound is used as a research and development standard for HPLC, as well as an impurity standard for riboflavin. It is also used in the synthesis of drugs and pharmaceuticals, such as antibiotics and antiviral agents. Riboflavin 3',4'-diphosphate can be synthesized from natural or synthetic sources.</p>

<p>Alloc bromoridane is a drug product that contains the active ingredient bromoridane. Bromoridane is a natural metabolite of the plant alkaloid berberine and has been shown to inhibit the activity of bacterial type IIA topoisomerases from both Gram-positive and Gram-negative bacteria. The chemical name for Alloc bromoridane is 2-[2-(4-bromobenzoyl)phenyl]dihydropyrimidine, and it has CAS number 117348-70-6. Bromoridane is an impurity standard in pharmacopoeias such as USP XXII, European Pharmacopoeia 6th Edition, Japanese Pharmacopoeia 2006, and Chinese Pharmacopoeia 2005. Alloc bromoridane is used in research and development for pharmaceuticals or as an analytical reference material.</p>

<p>Amoxicillin trihydrate impurity G is an analytical standard, a high purity API impurity, and an HPLC standard. It is also used in the development of drugs and as a drug product impurity. Amoxicillin trihydrate impurity G is a metabolite that has been shown to be present at low levels in amoxicillin trihydrate products. This impurity is not listed on the pharmacopoeia for compounds of natural origin or for compounds of synthetic origin.</p>

<p>Please enquire for more information about Diglutathionyl mustard phosphoramide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Racemic norphenylephrine hydrochloride is a sympathomimetic amine. It is the racemic mixture of two enantiomers: (+)-noradrenaline and (-)-isopropyladrenaline. Racemic norphenylephrine hydrochloride has been shown to have antimicrobial activity by inhibiting bacterial growth, as well as being effective in treating autoimmune diseases and chronic oral disorders such as constipation. Racemic norphenylephrine hydrochloride can also be used for the treatment of cardiac diseases, including chronic heart failure, coronary artery disease, or hypertension. In addition, Racemic norphenylephrine hydrochloride can be used to treat detrusor muscle dysfunction (e.g., urinary incontinence).</p>

<p>Dibenzazepine-10,11-dione is a dibenzazepine that has been used as a solvent in pharmacopoeias. It has been shown to stabilize the solvents and increase the rate of dissolution of other compounds. Dibenzazepine-10,11-dione can be sublimed or recrystallized from solvents such as chloroform, acetone, ethanol, benzene, ethers, and halogenated hydrocarbons. The compound is orthorhombic at room temperature and can be converted to monoclinic by heating or cooling. This compound has not been extensively studied because it is insoluble in water.</p>

<p>Please enquire for more information about 3-(1,1-Difluoro-2-propen-1-yl)-2(1H)-quinoxalinone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dibenzhydryl disulfide is a compound that includes sulfide and olefinic groups. It is an impurity in the reaction products of sulfide with olefins, which may be removed by washing, distillation, and crystallization. Dibenzhydryl disulfide has been shown to react with nucleophiles (e.g., OH-, CO2) to form an anion or proton. The reaction mechanism for this product is not well understood, but it most likely proceeds through the intermediacy of diphenylmethane. The product can also undergo a transfer reaction with butyllithium or thiobenzophenone to form methylbenzene, ethylbenzene, or propylbenzene respectively.</p>

<p>Please enquire for more information about 3’-o-Benzyl-(1R)-hydroxy tapentadol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1,1-Dimethylethyl (3S,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6- heptenoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 7-Hydroxy warfarin β-D-glucuronide disodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Mercaptopurine impurity standard is a drug product that is used as an analytical reference standard in the development of drugs. Mercaptopurine impurity standard is a natural metabolite of 6-mercaptopurine, which is used to treat leukemia and other forms of cancer. It has been shown to have an anti-inflammatory effect, but this has not been confirmed. Mercaptopurine impurity standard is a synthetic compound that is made synthetically for use as an impurity standard. It has also been shown to be metabolized by cytochrome P450 enzymes, glutathione reductase, or conjugation with glucuronic acid. Mercaptopurine impurity standard has been shown to be stable under acidic conditions and heat treatment at temperatures up to 200°C.</p>

<p>Desmethyl dabrafenib is a synthetic drug product that is used in research and development. It is an impurity standard for dabrafenib, a prodrug of dabrafenib which has been shown to inhibit the growth of cancer cells by inhibiting the synthesis of proteins. Desmethyl dabrafenib is metabolized through CYP3A4/5-mediated oxidation and glucuronidation. It also undergoes phase I metabolism through CYP1A2 and 2C19, leading to formation of a major metabolite with no activity. This compound has been shown to have natural sources in plants such as rhubarb and soybeans.</p>

<p>Carfilzomib is a drug product that belongs to the class of drugs called proteasome inhibitors. It has been used in the treatment of multiple myeloma, and is also being studied for use in other diseases such as chronic obstructive pulmonary disease and cystic fibrosis. Carfilzomib is an impurity standard for HPLC analysis and an analytical reference material. It is also used as a pharmacopoeia reference material. Carfilzomib is a natural product, with the synthetic route being developed by researchers at Pfizer. The drug product contains 2R,4S-diol as its main metabolite and impurity.</p>

<p>tert-Butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate is an impurity that is found in the production of tert-butyl 4-(4,5,6,7,8,9,10-hexahydrobenzo[a]pyrido[1,2:4,3]triazin-2(3H)-yl)piperazine-1 carboxylate. It has been used as a reference standard for HPLC. This compound is not active when administered orally and does not exhibit any pharmacological activity.</p>

<p>N-Carbomethoxyamoxapine is an analytical standard and impurity in the synthesis of a drug product. It is a metabolite of amoxapine, which belongs to the group of tricyclic antidepressants. N-Carbomethoxyamoxapine has been used as an analytical standard for HPLC analysis and as a reference material for pharmacopoeia. It is also an impurity in the synthesis of amoxapine and other pharmaceuticals.</p>

<p>Imatinib is a drug substance that belongs to the class of imidazole and phenylpiperidine derivatives. It is used in the treatment of leukemia and other cancers. Imatinib has been shown to inhibit tumor cell proliferation by inhibiting protein synthesis via inhibition of ribosomal activity, leading to cell death. Imatinib also inhibits the activation of PPARγ, an important transcription factor involved in lipid metabolism. The presence of impurities may affect the therapeutic efficacy or safety of this drug, so it is important to know what impurities are present in order to avoid unexpected side effects.</p>

<p>This product is a research and development (R&amp;D) chemical. It's an impurity standard for the synthesis of 6,7,8,9-tetrahydrocarvedilol. The purity of this compound is greater than 98%. This chemical is used in drug development studies, analytical methods and pharmacopoeia standards.</p>

<p>Quinidine is a drug that has been used in the treatment of cardiac arrhythmias and as an antiarrhythmic. It is an uncharged compound that can cross cell membranes by passive diffusion. Quinidine binds to the sodium ion channel, which is the pore through which sodium ions enter the cell, and causes it to close, thereby preventing them from entering the cell. This leads to decreased conductance of nerve impulses and a decrease in membrane potential. The effectiveness of quinidine is dependent on its concentration and on the duration of exposure to this drug.</p>

<p>Way 629 hydrochloride is a chemical compound that belongs to the class of synthetic, pharmacopoeia and drug development. It is used as an impurity standard and a custom synthesis. Way 629 hydrochloride is also used in the study of metabolism. This compound has been shown to be metabolized by cytochrome P450 enzymes, glucuronidases, glutathione reductase, or conjugation with glucuronic acid.</p>

<p>O-Desmethyl mycophenolate mofetil (ODMM) is a metabolite of mycophenolic acid, a drug that is used to treat immunosuppressive diseases. ODMM can be synthesized in the laboratory and used as an analytical standard for mycophenolic acid and its metabolites. ODMM is also a metabolic product of mycophenolate mofetil, which has been shown to have anti-inflammatory properties.</p>

<p>Cyamemazine sulfoxide is a histamine H1 receptor antagonist. It has been shown to have strong affinity for the serotonin 5-HT2C and dopamine D2 receptors, as well as the atrial 5-HT2A receptors. Cyamemazine sulfoxide has a low oral bioavailability of about 10% and is metabolized in the liver to cyamemazine and its active form, cyamemazine sulfoxide. Cyamemazine sulfoxide binds to serotonin 5-HT2C receptors with a high affinity, which leads to inhibition of serotonin release from nerve endings in the brain. This drug also inhibits dopamine release from nerve endings in the brain and has been shown to have cardiac effects on heart rate and contractility.</p>

<p>Rotogotine EP Impurity J is a synthetic drug that is metabolized to produce the active form, rotogotine. Rotogotine is used in the treatment of Parkinson's disease and restless leg syndrome. This impurity standard may be used as a reference for analytical methods such as HPLC or GC.</p>

<p>N-Desmethyl sorafenib (pyridine)-N-oxide is a drug product that can be used as an HPLC standard and is also used in the development of drugs. CAS No. 583840-04-4 is a metabolite impurity that can be found in the analytical API impurity of the drug. This synthetic compound is subject to metabolism studies, which are conducted on animals for pharmacopoeia purposes. N-Desmethyl sorafenib (pyridine)-N-oxide has shown niche applications in the field of research and development, as it can be used as an analytical standard for HPLC.</p>

<p>Please enquire for more information about Nonanal-d18 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Carbofuran N,N-dibutyl-3λ1-trisulfan-1-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(+)-SHIN1 is an analog of a compound found in human urine that has shown promising results in the fight against cancer. It functions as a kinase inhibitor, which means it prevents the activation of proteins that are involved in cancer cell growth and tumor formation. Studies have indicated that (+)-SHIN1 induces apoptosis (programmed cell death) in Chinese hamster ovary cells and inhibits the growth of various cancer cell lines. This compound has also been investigated for its potential use in treating Alzheimer's disease, as it shares structural similarities with donepezil, a drug used to treat cognitive impairments associated with this condition. (+)-SHIN1 represents a promising avenue for anticancer drug development and may hold great potential for improving cancer treatment outcomes.</p>

<p>Ivermectin B1 aglycon is a drug product that is custom synthesized, high purity, and analytical. It is natural and synthetic and has a niche in the market. It is used for metabolic studies and drug development purposes. Its metabolite are impurities that are found in pharmacopoeia. Ivermectin B1 aglycon is a metabolite of ivermectin, which has been shown to have anti-inflammatory properties.</p>

<p>9-Epimitomycin B is a water-soluble, alkoxy-substituted amino compound that is used medicinally. It has antibacterial activity and has been shown to be effective against Gram-positive bacteria such as Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis. 9-Epimitomycin B inhibits the growth of these bacteria by binding to their ribosomes and inhibiting protein synthesis. The carbon atoms in 9-epimitomycin B are linked to an alkoxy group at one end, which causes it to have a higher affinity for bacterial ribosomes than human ribosomes. 9-Epimitomycin B also binds to mitomycin C, which may be responsible for its antimetabolite properties.</p>

<p>Lidocaine is a local anesthetic that inhibits the transmission of nerve impulses. Lidocaine-d10 hydrochloride is a drug product that contains lidocaine and deuterium-labeled lidocaine, which has been chemically synthesized to contain deuterium atoms in place of hydrogen atoms. Lidocaine-d10 hydrochloride is used as an analytical standard for pharmacological studies and drug development. It also serves as an impurity standard in the synthesis of other compounds. Lidocaine-d10 hydrochloride is metabolized through oxidation and reduction, forming metabolites such as 4-hydroxylidocaine, 4-dehydroxylidocaine, and 2,6-dehydroxylidocaine.<br>Lidocaine-d10 hydrochloride can be used to study the metabolism of lidocaine and its metabolites, which are important for drug development.</p>

<p>Mutagen X is an anticancer drug that works by inhibiting kinases, which are enzymes involved in cell cycle regulation and apoptosis. It has been shown to be effective against a variety of human cancer cells, including those from Chinese hamsters. Mutagen X is a potent inhibitor of protein kinases, which play a key role in the growth and proliferation of cancer cells. It has been found to have a high level of potency against tumor cells and can be used as a medicinal drug for cancer treatment. Mutagen X also acts as an inhibitor in urine and has been shown to be effective against various inhibitors.</p>

<p>(3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt is an impurity standard for the drug product. It is a synthetic metabolite that binds to proteins and has been found in human urine. The chemical synthesis of (3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6 heptenoic acid sodium salt was performed using a high purity custom synthesis and high purity pharmacopoeia grade reagents.</p>

<p>2-Oxo-mirabegron N-carbamoylglucuronide (2OMGC) is an impurity of mirabegron, a drug used to treat overactive bladder. 2OMGC is a metabolite of mirabegron that is created through the hydrolysis of the carbamate group on the nitrogen atom. This impurity can be detected in HPLC and GC/MS analyses and has been found in the urine of patients taking mirabegron. The detection limit for this impurity is 10 ng/mL. 2OMGC exhibits pharmacological activity similar to that of its parent compound, mirabegron, which is purported to have antispasmodic and anal sphincter relaxant properties.</p>

<p>RS 67506 hydrochloride is a biochemical that is used in experimental and descriptor studies. The ketone group has been found to be an important part of the molecular structure. RS 67506 hydrochloride has been shown to have a number of biological properties, including inhibition of the synthesis of neurotransmitters such as dopamine, serotonin and norepinephrine; it also has anti-nervous system activity. This chemical was also found to inhibit the synthesis of prostaglandin E2 in human neutrophils. It is hypothesized that RS 67506 hydrochloride may inhibit phospholipase A2, which would prevent the release of arachidonic acid from phospholipids into the cell membrane and block the production of eicosanoids.</p>

<p>Enniatin B2 is a natural cyclic hexadepsipeptide that has been isolated from Chinese medicinal herbs. It is an analog of enniatin, which is known to be a potent inhibitor of protein kinase C. Enniatin B2 has been shown to induce apoptosis in cancer cells and inhibit tumor growth in human cell lines. It exerts its anticancer effects by disrupting the cell cycle and inhibiting the activity of various protein kinases involved in cell signaling pathways. Enniatin B2 also exhibits inhibitory effects on urease, which makes it a potential therapeutic agent for urinary tract infections caused by urease-producing bacteria. Its unique characteristics make it a promising candidate for further research into its potential as an anticancer and antimicrobial agent.</p>

<p>Please enquire for more information about Edaravone d5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Vaniliprole is a vitamin analog that exhibits anticancer properties by inhibiting tumor growth and inducing apoptosis in cancer cells. It acts as a protein kinase inhibitor, which prevents the activation of kinases that play a crucial role in cell division and proliferation. Vaniliprole has been shown to be effective against various types of cancer cells, including those derived from humans and Chinese hamsters. This compound is excreted through urine and has potential as an anticancer agent for future drug development.</p>

<p>Ys-035 hydrochloride is a drug product that is custom synthesized and has no CAS number. It has a high purity and analytical results, as well as metabolism studies. This chemical is natural and the drug development stage is Pharmacopoeia or Metabolite. Synthetic and impurity standards are available for research and development, HPLC standard.</p>

<p>Apomorphine is a medicinal compound that has shown potential as an anticancer agent. It works by inhibiting protein kinases, which are enzymes that play a crucial role in the regulation of cell cycle and apoptosis. Apomorphine has been shown to induce apoptosis in human cancer cells, including leukemia cells. It also acts as an inhibitor of angiogenesis, which is the formation of new blood vessels that are necessary for tumor growth. In addition, apomorphine has been studied for its potential to enhance the effectiveness of other cancer treatments, such as nintedanib. Its ability to target cancer cells while sparing healthy cells makes it a promising candidate for cancer therapy.</p>

<p>Please enquire for more information about (3,5-Dimethyl-2-hexeno)-4-hydroxyphenone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Descarboxy treprostinil is a synthetic drug product that is used as a research and development impurity standard. It has a purity of 98% or greater, and its CAS number is 101692-01-7. Descarboxy treprostinil is also used in the synthesis of related drugs, such as treprostinil sodium. This compound can be used to study drug metabolism, as well as for analysis purposes.</p>

<p>Sesamol-d2 is an oral prodrug that belongs to the class of morpholinos. It acts as a mitochondrial DNA ligase inhibitor, preventing the repair of oxidative damage to DNA. Sesamol-d2 has been shown to reduce fungal biomass and inhibit RNA concentration in a reaction solution containing adenine and tenofovir alafenamide hemifumarate. It also inhibits base-excision repair, leading to increased levels of oxidative DNA damage. Furthermore, Sesamol-d2 has been found to have plasma-level effects on various impurities, as demonstrated through molecular docking studies.</p>

<p>Please enquire for more information about 5-Hydroxydeferasirox including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-2-Amino-5-phosphonovaleric acid is an inhibitory neurotransmitter that binds to the GABAA receptor. It is used in the treatment of bladder disorders, such as urinary frequency, urgency, and incontinence. L-2-Amino-5-phosphonovaleric acid has been shown to have a depressant effect on the central nervous system and can cause symptoms such as nausea, vomiting, and headache. This drug also has antimicrobial properties due to its ability to inhibit bacterial enzyme activities. L-2-Amino-5-phosphonovaleric acid blocks glutamate receptors in mouse hippocampal cells by binding the alpha1 subunit of the GABAA receptor. This prevents the influx of calcium ions into cells and inhibits phosphorylation of protein kinase C. L(+)-2-Amino-5-phosphonovaleric acid also inhibits pentosan polysulfate sodium,</p>

<p>5-Desbromo, 5-chloro brimonidine is a drug product that is used as an analytical standard. It has been shown to be metabolized by CYP3A4 and CYP2D6 enzymes.</p>

<p>Please enquire for more information about Atorvastatin lactam allyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>