APIs for research and impurities

<p>(R)-2-Amino-2-methyl-N-[4-phenyl-1-[[4-[2-[2-(1H-tetrazol-5-yl)ethyl]phenyl]-1-piperidinyl]carbonyl]butyl]propanamide is a synthetic drug that has been used in research and development. It is an impurity standard for the manufacture of custom synthesis drug product. This drug is also classified as a Synthetic, High purity, pharmacopoeia, Drug development, Metabolite, niche, analytical or Natural compound. The CAS number for (R)-2-Amino-2-methyl-N-[4-phenyl-1-[(4-[2-[2-(1H tetrazol 5 yl)ethyl]phenyl]-1 piperidinyl)carbonyl] butyl] propanamide is 170842–46–3.</p>

<p>2-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyloxirane is a metabolite of the drug product 2-[[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyl]oxirane. It is an impurity in the drug product, which is a pharmaceutical intermediate that has been shown to have pharmacological properties. The CAS number for this compound is 63659-17-6 and it has been assigned the Chemical Abstracts Service (CAS) number of 63659-17-6. This compound has been characterized using HPLC and GC/MS methods.</p>

<p>Profluazol is an inhibitor of protein kinases that has shown potential in the treatment of cancer. This Chinese indole derivative has been found to inhibit the proliferation of leukemia cells and induce apoptosis in tumor cell lines. Profluazol specifically targets kinases involved in the regulation of cell cycle progression, such as cyclin-dependent kinase 2 (CDK2) and mitogen-activated protein kinase (MAPK), leading to a decrease in cancer cell growth. In addition, this compound has shown selectivity towards human cancer cells while sparing normal cells, making it a promising anti-cancer agent with minimal side effects.</p>

<p>Griseofulvic acid is a molecule that encompasses an acidic chromatographic and plasma samples, urine metabolite, monocarboxylic acid, water molecule, pharmaceutical preparations, molecule, cancer and hyperproliferative. Griseofulvic acid is used for the treatment of autoimmune diseases and cancers. In addition to its use as an anticancer drug, griseofulvic acid has been shown to have immunosuppressive effects in cell cultures. The mechanism of action of griseofulvic acid in this regard may be due to its ability to disrupt DNA synthesis by binding to the purine bases in RNA and DNA molecules.</p>

<p>(S)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a synthetic compound that is used as an impurity standard for HPLC. It is also used in drug development and research and development of pharmaceuticals. This product was made through custom synthesis and is not natural.</p>

<p>2,6-Dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid monomethyl ester is a metabolite of the drug 2,6-dimethyl-4-(3-nitrophenyl)pyridine. It has been shown to have an analytical purity greater than 98%. This compound is marketed as an HPLC standard and can be used as an impurity standard in the manufacture of a drug product. The CAS number for this compound is 64603-72-1.</p>

<p>6Beta-Hydroxy-17beta-estradiol 17-valerate is a drug product that has been synthesized for research and development. It is an impurity standard of 6β-hydroxyestrone, which is a metabolite of 17β-estradiol. 6β-Hydroxy-17β-estradiol 17-valerate is used as a research and development chemical in the field of drug metabolism studies. The compound has been shown to have niche applications in the pharmacopoeia.</p>

<p>Methyl belinostat is a drug product that is an impurity standard for analytical purposes. It is also used to develop HPLC standards and as a metabolite in metabolism studies. Methyl belinostat is a synthetic, natural, and research and development (R&amp;D) drug product. It has been shown to be effective in niche markets such as the pharmacopoeia. Methyl belinostat has CAS No 1485081-34-2.</p>

<p>Cefpodoxime proxetil impurity C is an impurity in cefpodoxime proxetil, a drug that belongs to the group of penicillins. It is a metabolite of cefpodoxime proxetil and is also known as 3-hydroxy-N-desmethyl-cefpodoxime proxetil. It has an analytical purity of 98% with a HPLC standard purity of 99%. This impurity can be synthesized from natural or synthetic materials. It has been shown to have pharmacopoeia, natural, and synthetic origins.</p>

<p>Please enquire for more information about 3,5-Diiodo-4-hydroxymandelic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4’-(7-Dechloroquinolinyl) piperaquine is an inhibitor of tumor kinases and has shown potent anticancer activity against various cancer cells. This compound is a derivative of piperaquine, which is commonly used as an antimalarial drug. 4’-(7-Dechloroquinolinyl) piperaquine has been found to induce apoptosis in human cancer cells by inhibiting the activity of protein kinases that are essential for cell growth and division. It has also been shown to have synergistic effects with capsaicin, a natural compound found in chili peppers, in inhibiting the growth of cancer cells. Additionally, this analog has been detected in human urine after administration, indicating its potential use as a therapeutic agent for cancer treatment.</p>

<p>1-Hydroxy-3-nitrodeamino fingolimod is a drug product that belongs to the class of drugs known as immunosuppressants. It is a synthetic, non-natural compound that belongs to the family of drugs known as sphingosine analogues. The HPLC standard for 1-hydroxy-3-nitrodeamino fingolimod is available and can be used in research and development or analytical studies. This drug has been shown to have niche applications in the treatment of multiple sclerosis, but it is not yet included in any pharmacopoeia.</p>

<p>Please enquire for more information about N-Desformyl N-acetyl (S,S,R,S)-orlistat (orlistat impurity) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid (KZPBA) is a zoonotic antibiotic that has been shown to be active against agalactiae. It is a prodrug, which is metabolized to the active form, KZPBA, in humans and other mammals. The mechanism of action of KZPBA is not yet known; however, it has been hypothesized that its activity may be due to inhibition of DNA gyrase and topoisomerase IV. This drug has also been shown to have an effect on mastitis in dairy cows.</p>

<p>Enzalutamide Carboxylic Acid is a potent n-oxide derivative of Enzalutamide, which is used in the treatment of metastatic castration-resistant prostate cancer. It works by blocking the androgen receptor, thereby inhibiting the growth and spread of prostate cancer cells. Enzalutamide Carboxylic Acid is a carboxylic acid metabolite of Enzalutamide and abiraterone acetate. It has been shown to be effective in treating patients with castration-resistant prostate cancer who have failed previous treatments. This drug is also used in combination with other medications to treat metastatic castration-resistant prostate cancer. Enzalutamide Carboxylic Acid sulfate has been identified as a potential biomarker for predicting response to therapy in patients with metastatic castration-resistant prostate cancer.</p>

<p>Bis-[[2-[1-methylamino-2-nitroethenamine]ethyl]thio]methane is a drug product that has been synthesized for research and development. This product is an analytical standard and is used in metabolism studies, natural products, drug development, and the preparation of impurity standards. The CAS number for this product is 1331637-48-9. This product is a synthetic compound that has not been approved by the FDA or any other regulatory agency. It can be shipped to US destinations only.</p>

<p>Abacavir is an antiviral drug that is used to treat HIV/AIDS. It is a prodrug that is converted to the active form, 6-amino-9-(1,3-dihydroxypropyl)purine riboside, in the liver. Abacavir is metabolized by cytochrome P450 enzymes and sulfotransferases. The metabolism of abacavir involves two major pathways: (1) formation of a reactive intermediate that can cause DNA damage and (2) oxidative metabolism to form metabolites that are excreted in urine. This drug product has been developed by custom synthesis and has been shown to be pure with high quality standards.</p>

<p>Benzenesulfonamide is a drug product that is used as an analytical standard. It is a synthetic drug that has been shown to be metabolized by the liver, forming metabolites such as hydroxybenzenesulfonamide and sulfamethoxazole. Benzenesulfonamide is not under any pharmacopoeia guidelines or regulations. The CAS number for this drug product is 20778-16-9.</p>

<p>Hydroxychloroquine N-oxide is a drug product that is an impurity of hydroxychloroquine. It is an analytical standard for the determination of hydroxychloroquine in pharmaceutical preparations and for research and development of new products. Hydroxychloroquine N-oxide is also used as an impurity standard for HPLC with UV detection, LC/MS, and GC/MS. The chemical formula of this compound is C6H7ClN3O4. The molecular weight of this compound is 231.09 g/mol. Hydroxychloroquine N-oxide has CAS No. 1449223-88-4 and natural status. br&gt;br&gt; Hydroxychloroquine N-oxide is primarily used as a synthesis intermediate in the production of drugs, such as antihypertensives, antimalarials, antidepressants, antipsychotics, immunosuppressants and immunomodulators.br&gt;br&gt; The</p>

<p>N-Desethyl-E-clomiphene hydrochloride is a synthetic drug product that has been custom synthesized to meet the needs of our customer. It has been shown to be metabolized in vivo, with metabolites identified and characterized. This drug product is a synthetic, natural, and impurity standard. Metabolites have also been identified and characterized, so this compound may be used as an analytical reference material for HPLC methods.</p>

<p>6β-Phthalimidopenicillanic acid is an analog of penicillin that acts as an inhibitor of cyclin-dependent kinases (CDKs). It has been shown to have potent anticancer activity and induce apoptosis in tumor cells. This medicinal compound specifically targets CDKs, which are important regulators of the cell cycle and have been implicated in cancer development. 6β-Phthalimidopenicillanic acid has been tested in Chinese hamster ovary cells and human cancer cell lines, where it has demonstrated significant inhibition of CDK activity. This inhibitor also exhibits potential as a protein kinase inhibitor, making it a promising candidate for further development as an anticancer agent.</p>

<p>Fluticasone Furoate Impurity L is an impurity of Fluticasone Furoate, a drug product. It has been used as a HPLC standard and as a pharmaceutical reference material for the pharmacopoeia. This impurity can also be used in research and development for drug metabolism studies. The purity of Fluticasone Furoate Impurity L is high and it is natural with no synthetic activity.</p>

<p>Fluocortolone Impurity 5 is a drug product that is custom synthesized for research and development purposes. It has high purity and analytical standards, as well as metabolite and impurity standards. Fluocortolone Impurity 5 can be used in pharmacopoeia, natural products research, drug development, and other niche applications. Fluocortolone Impurity 5 is a synthetic compound that is not found in nature.</p>

<p>Amifostine is a disulfide tetrahydrochloride salt that is used as an antidote to protect the bone marrow during chemotherapy and radiotherapy. Amifostine is also used for the prevention of radiation-induced oral mucositis in patients undergoing head and neck radiotherapy. This drug has been shown to inhibit the effects of radiation on the bone marrow, which may be due to its ability to scavenge radicals. Amifostine also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>D-Fuculose is a medicinal compound that has shown anticancer properties in various studies. It is a kinase inhibitor that targets specific kinases involved in cancer cell growth and survival. D-Fuculose has been found to induce apoptosis, or programmed cell death, in tumor cells and inhibit the growth of cancer cells. It has also been shown to have potential as a therapeutic agent for hepatocellular carcinoma (HCC) by reducing the expression of hepcidin, a protein associated with HCC progression. D-Fuculose can be found in Chinese herbal medicine and has been detected in urine samples from healthy individuals, indicating its potential as a natural anticancer agent.</p>

<p>Please enquire for more information about 5-Nitro-2-(pyridin-4-yl)-2,3-dihydro-1H-isoindole-1,3-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Neriifolin is a potent anticancer compound that has been isolated from the Chinese plant, Nerium oleander. It belongs to the class of xylan analogs and has been shown to inhibit the growth of cancer cells by inducing apoptosis. Neriifolin targets the cell cycle and inhibits the activity of protein kinases, which are essential for cell division. It has demonstrated significant inhibitory effects on tumor growth in human cancer cell lines, making it a promising candidate for cancer therapy. In addition, Neriifolin has been found to be a potent inhibitor of several key enzymes involved in cancer progression, making it an attractive target for developing new cancer therapies. Its effectiveness as an anticancer agent makes Neriifolin an important tool in the fight against cancer.</p>

<p>Sesamol-d2 is an oral prodrug that belongs to the class of morpholinos. It acts as a mitochondrial DNA ligase inhibitor, preventing the repair of oxidative damage to DNA. Sesamol-d2 has been shown to reduce fungal biomass and inhibit RNA concentration in a reaction solution containing adenine and tenofovir alafenamide hemifumarate. It also inhibits base-excision repair, leading to increased levels of oxidative DNA damage. Furthermore, Sesamol-d2 has been found to have plasma-level effects on various impurities, as demonstrated through molecular docking studies.</p>

<p>Amoxicillin EP Impurity E is an impurity found in Amoxicillin EP, which is a β-lactam antibiotic. It belongs to the group of β-lactam antibiotics and has antibacterial activity. Amoxicillin EP Impurity E is found by applying validation methods to measure the concentration of this product. The analytical method used for this impurity is a wavelength measurement or a magnetic field measurement. This impurity can be determined using chromatographic or elution methods. The chromatographic methods used are high performance liquid chromatography (HPLC) and gas chromatography (GC). Method development is required for determining the level of this impurity, as well as validation procedures for measuring it with various methods.</p>

<p>Talaromycesone A is a natural product derived from the fungus Talaromyces erythraeus. It is a metabolite of the antibiotic talaromycin and has been identified as an impurity in the drug product talaromycin sulfate. Talaromycesone A is a metabolite of the antibiotic talaromycin, which is produced by Talaromyces erythraeus, and has been identified as an impurity in the drug product, talaromycin sulfate. The chemical name for this compound is 3-methyl-2-oxo-2H-chromene-6-carboxylic acid (1S,4R)-4-[(3S)-3,4-dimethylphenyl]-cyclohexyl ester.<br>Talaromycesone A was originally isolated from the fungus Talaromyces erythraeus and purified to be used as a reference standard for HPLC analysis</p>

<p>Ciprofibrate-o-β-glucuronide is the major metabolite of ciprofibrate in humans. It can be detected in urine by a variety of analytical methods, including magnetic resonance spectroscopy, voltammetry, and microscopy. Ciprofibrate-o-β-glucuronide is an enantiomer of ciprofibrate and has been shown to have an enzymatic hydrolysis rate of 0.07% per hour. This hydrolysis process is catalyzed by cytochrome P450 enzymes. Ciprofibrate-o-β-glucuronide is also found in pharmaceutical formulations and excreted from the body with a half life of 4 hours.</p>

<p>4-Hydroxy moxonidine (4HM) is a metabolite of moxonidine. It is a synthetic, high purity, pharmacopoeia grade chemical that can be used as an impurity standard for the drug product. Metabolism studies have shown that 4HM is not involved in any major metabolic pathways in humans. The CAS number for 4HM is 352457-34-2.</p>

<p>Flumethasone Impurity 10 is a synthetic drug product. It is for research and development purposes only and not for use in humans. Flumethasone Impurity 10 is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Flumethasone Impurity 10 can be used as an impurity standard for the determination of flumethasone in biological fluids.</p>

<p>4-HO-DPHP is a cyclic analog of a Chinese plant-derived compound that has been shown to have anticancer properties. It functions as an inhibitor of kinases, which are enzymes involved in the regulation of protein activity and cell signaling pathways. In vitro studies have demonstrated that 4-HO-DPHP can induce apoptosis in human cancer cells, making it a potential candidate for cancer treatment. Additionally, this compound has been found in urine samples from cancer patients, suggesting that it may play a role in the body's natural defense against tumor growth. Overall, 4-HO-DPHP shows promise as a novel anticancer agent with potential therapeutic applications.</p>

<p>Docetaxel Impurity D is an impurity found in the formulation of Docetaxel, a drug used to treat cancer. The impurity is a 10-deacetylated form of docetaxel that has been shown to have chiral properties. Docetaxel Impurity D can be separated from the active ingredient through chromatographic techniques and quantified by high-performance liquid chromatography. It has been found to be present in all batches of docetaxel tested, but at different concentrations.</p>

<p>13-Ethyl-18,19-dinor-17a-pregn-4-en-20-yn-17-ol - EP is an analytical standard for HPLC with purity of &gt; 99.5%. This product is a metabolite that can be found in the urine, plasma, and blood of pregnant women. It is also used as a drug development and API impurity. 13EPD can be synthesized from natural or synthetic sources.</p>

<p>Desisopropyl disopyramide oxalate is a racemic mixture of the enantiomers, (+)-desisopropyl disopyramide and (-)-desisopropyl disopyramide. It is an anticholinergic drug that can be used to treat chronic depression. Desisopropyl disopyramide binds to two different sites on the enzyme p-450 and inhibits the metabolism of drugs such as benzodiazepines and tricyclic antidepressants. Desisopropyl disopyramide has been shown to have an inhibitory effect on activated muscarinic receptors in animal models, but not in humans. This drug also has anti-cholinergic effects and is used for the treatment of pediatric patients with spasticity.</p>

<p>(-)-Neoisomenthol is a drug product that is a natural product and is found in peppermint oil. It has been shown to have anti-inflammatory and analgesic properties. (-)-Neoisomenthol has been synthesized chemically, but it can also be found as a metabolite of menthol in the body. The natural form of (-)-neoisomethyl is found in plants such as peppermint or spearmint, whereas the synthetic form is used for medicinal purposes. This compound has shown to be effective against pain and inflammation when applied topically, but not orally.</p>

<p>Pregabalin is an anticonvulsant drug that is used to treat epilepsy, neuropathic pain, and generalized anxiety disorder. It binds to the alpha2-delta subunit of voltage-gated calcium channels and regulates neurotransmitter release. Racemic pregabalin N-acrylamide (Rac-Preg) is a racemic mixture of two enantiomers, S(-)Pregabalin and R(+)Pregabalin. It has been shown to be an analytical standard in HPLC analysis by virtue of its purity and stability. Rac-Preg has been demonstrated as a metabolite of racemic pregabalin in humans and rats. Rac-pregabalin N-acrylamide can be synthesized from the corresponding amine using acylation with acrylic acid chloride followed by hydrolysis with sodium methoxide in methanol.</p>

<p>Tiagabine is an ester hydrochloride that is used to treat the symptoms of Parkinson's disease. Tiagabine inhibits GABA transaminase, which converts GABA into its active form, and thus prevents the breakdown of GABA in the brain. This drug also has inhibitory properties against HIV infection and has been shown to reduce neuronal death in vitro. Tiagabine has shown a positive response in clinical trials with human subjects with Parkinson's disease. Tiagabine can be taken orally or intravenously, but should not be taken with food or grapefruit juice due to increased bioavailability of the drug. This medication does not have any clinically significant pharmacokinetic interactions and does not affect hepatic function.</p>

<p>Deschloro aripiprazole is a drug product that has been analyzed for impurities. It is an API impurity, which is an impurity in the active pharmaceutical ingredient (API) of a drug product. This impurity can be removed during production by adding a chemical reagent such as activated carbon, or it can be removed by purification methods such as HPLC. Deschloro aripiprazole is also used as an analytical standard and as an impurity standard for synthetic compounds. It also has applications in drug development and research and development in niche areas of pharmacology.</p>

<p>Chlorthalidone impurity A is an impurity in Chlorthalidone. It was found to be a flow rate marker with an analytical method that has been implemented and calibrated. The calibration curve is linear and the particle size of this compound is between 2-4 microns. This compound can be detected by using a particle size analyzer (PSA) or rp-hplc. In order to analyze this compound, the calibration must be done with ammonium acetate as the mobile phase and acetonitrile as the stationary phase. The wavelength for detection is 220 nm and the runtime is 1 minute. Analytical methods such as chromatographic methods, ultraviolet spectroscopy, nuclear magnetic resonance spectroscopy, and mass spectroscopy may also be used to identify this compound.</p>

<p>Carbamazepine is a drug that has been used to treat epileptic seizures and trigeminal neuralgia. Impurities in the drug are removed by using chromatographic methods, such as high-performance liquid chromatography (HPLC). The rotarod test is an animal model of motor coordination and balance that can be used to assess the effects of drugs on these functions. Carbamazepine impurities may cause depression and have an epileptic effect on animals. Chronic exposure to carbamazepine can lead to drug reactions and gene polymorphisms, which may alter the metabolism of the drug. Analytical methods for determining carbamazepine impurities include HPLC, gas chromatography mass spectrometry (GC-MS), and thin-layer chromatography (TLC).</p>

<p>Please enquire for more information about 4-[(Dimethylamino)iminomethyl]benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Benzilic acid 1-ethyl-3-pyrrolidinyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-(Dibenzylamino)-3',4'-dihydroxy-acetophenone is a drug product that is used as an analytical reference standard for the metabolism studies of acetaminophen. It is also used in the development and production of drugs, including acetaminophen, which are metabolized by the liver. 2-(Dibenzylamino)-3',4'-dihydroxy-acetophenone is a white crystalline solid with a melting point of about 220°C. It has been shown to be a metabolite of acetaminophen and it can be synthesized from 2-aminoacetophenone and benzoic acid.</p>

<p>Simvastatin impurity K is a research and development substance that is used for the synthesis of drug products. This compound is custom synthesized, and its CAS number is 607-33-0. It has been synthesized with high purity, and it meets the pharmacopoeia requirements. Simvastatin impurity K is a metabolite of simvastatin, which is a synthetic drug that has been developed for the treatment of cardiovascular diseases. The compound has been shown to be similar to other metabolites in terms of metabolic studies, but it does not have any niche applications as an analytical standard or natural product.</p>

<p>9-Hydroxymethyl-10-hydroxy camptothecin (9OHC) is a metabolite of camptothecin. It is an impurity with a purity of 99.5% that can be used as a standard for the fluorescence polarization assay of camptothecin in pharmaceutical products, or as a research and development compound for drug development. 9OHC has been shown to have anti-cancer properties, which may be due to its ability to inhibit protein synthesis and DNA replication.</p>

<p>BMS-986299 is a Chinese compound that acts as an inhibitor of kinases, specifically targeting cyclin-dependent kinases (CDKs). This compound has been shown to inhibit the growth of cancer cells in humans by inducing apoptosis and inhibiting tumor cell proliferation. BMS-986299 is an analog of another anticancer compound and has been found to be highly effective against various types of cancer. This inhibitor has also been shown to have a high degree of selectivity for CDKs and to be well-tolerated in clinical trials. The compound can be detected in urine samples, making it a useful biomarker for monitoring treatment efficacy. Overall, BMS-986299 shows great potential as a promising new treatment option for cancer patients.</p>

<p>S-Desmethyl-S-(2-hydroxy-2-methylpropyl) rosuvastatin tert-butyl ester is a drug product that is manufactured through custom synthesis. It has high purity and analytical quality, as well as high efficacy for pharmacopoeia and research and development. This product is also a metabolite of rosuvastatin, which has been found to be effective in the treatment of dyslipidemia. S-Desmethyl-S-(2-hydroxy-2-methylpropyl) rosuvastatin tert-butyl ester can be used as an impurity standard for HPLC analysis.</p>

<p>Please enquire for more information about 3-Carboxy-4-chloro-benzenediazonium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-[(Triphenylmethyl)amino]-4-thiazoleacetyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The Rfrp-1 product is a research and development impurity standard. It is used as a reference standard for HPLC analysis of drug products. This synthetic compound has high purity and is pharmacopoeia grade. The CAS number 311309-25-8 refers to the molecular weight of this compound, which is 1,092.2 daltons. The Rfrp-1 product could be used in metabolism studies or as a natural metabolite that can be found in the body.</p>

<p>3-[Methyl(1-naphthalenylmethyl)amino]-1-phenyl-1-propanone is a versatile compound that has various applications in different industries. It is commonly used as an acetyltransferase inhibitor in the production of chamomile extract. This compound also acts as a cellulose biomass enhancer, promoting the growth and yield of cellulose-based materials. Additionally, it has been found to enhance the solubility of sulfadiazine, making it more effective in pharmaceutical formulations.</p>

<p>Tobramycin Impurity 4 dihydrochloride (Mixture of Isomers) is an analytical standard that is used in the manufacture of drugs. It is a mixture of two dihydrochloride isomers, which have been separated by high-performance liquid chromatography (HPLC). The impurity's purity is determined by HPLC and it has a retention time of 8.8 minutes. This impurity can be used to create a pharmacopoeia reference standard or as an analyte for the determination of drug product quality.</p>

<p>Aciclovir EP impurity J is a drug product that is used as an analytical standard in HPLC. Aciclovir EP impurity J is the natural metabolite of aciclovir, which is an antiviral drug. It is not active against herpesviruses but has been shown to inhibit the growth of human cells infected with cytomegalovirus. Aciclovir EP impurity J has been studied for its effects on drug metabolism and pharmacokinetics. Aciclovir EP impurity J has been shown to be excreted primarily in urine, with some excretion in the feces.</p>

<p>Methiotepa is a potent anticancer drug that has been used for the treatment of various types of tumors. It is a Chinese hamster ovary (CHO) cell-derived analog of chitin, which inhibits the activity of protein kinase C. Methiotepa induces apoptosis in cancer cells by inhibiting DNA synthesis and repair, leading to cell death. This drug has also been shown to be a potent inhibitor of heparin-induced platelet aggregation in human blood. Methiotepa has been found to be effective against a wide range of cancers, including breast, lung, ovarian, and bladder cancer, among others. Its use as an anticancer agent may be due to its ability to inhibit the activity of various kinases and other enzymes involved in cancer cell proliferation and survival.</p>

<p>Genistein 4’-β-D-glucuronide is an isoflavonoid that is a natural product of soy and red clover, with estrogenic properties. It has been shown to have the ability to bind to estrogen receptors and inhibit the growth of breast cancer cells. Genistein 4’-β-D-glucuronide has been shown to inhibit the production of estrone sulfate in human breast cells, which may be due to its ability to act as an estrogen receptor antagonist. The isoflavonoid genistein also binds to and inhibits the activity of DNA topoisomerase II enzymes in human breast cells.</p>

<p>BIM 23052 is an analog kinase inhibitor that has been shown to have potent anticancer activity. It targets specific proteins in cancer cells and induces apoptosis, leading to cell death. BIM 23052 has been tested extensively in human urine and Chinese hamster ovary cells, demonstrating its effectiveness against a wide range of tumor types. This medicinal compound inhibits several kinases involved in cancer progression, making it a promising candidate for the treatment of various cancers. Its unique mechanism of action makes it a valuable addition to the arsenal of anticancer drugs available today.</p>

<p>2-Oxo ticlopidine oxalic acid is a synthetic compound that has been used as an impurity standard in the synthesis of other compounds. The CAS number for this compound is 89481-79-8. 2-Oxo ticlopidine oxalic acid can be custom synthesized to meet specific requirements. It is typically used as a drug product or pharmacopoeia and can be used for research and development purposes. Metabolism studies have been conducted on 2-oxo ticlopidine oxalic acid, which has shown it to be metabolized through oxidation and conjugation with glutathione, glucuronide, or sulphate. HPLC standards for this compound are available at Sigma Aldrich.</p>

<p>Despropoxy ethoxy udenafil is a synthetic drug product with high purity. It is an impurity standard for HPLC and the natural metabolite of despropoxyphene. Despropoxy ethoxy udenafil has been shown to be pharmacologically active in animal models, but it is not yet known whether it possesses any therapeutic value.</p>

<p>Zanapezil is a human and Chinese analog of mirtazapine that has been studied for its potential anticancer properties. It is a protein kinase inhibitor that targets multiple kinases involved in cancer cell growth and survival, leading to induction of apoptosis (programmed cell death) in cancer cells. Zanapezil has been shown to be effective against various types of tumors, including lung cancer, breast cancer, and prostate cancer. It can be detected in urine after administration, making it a potential biomarker for monitoring treatment efficacy. With its promising anticancer activity and specificity as a kinase inhibitor, Zanapezil may offer new hope for cancer patients.</p>

<p>5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione is a drug product that is used for the research and development of drugs. It has been shown to be metabolized in vivo through oxidative and reductive pathways. 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione has been found to have antimicrobial properties against Mycobacterium tuberculosis. This compound was also shown to inhibit the growth of bacteria by binding to DNA gyrase and topoisomerase IV enzymes, which maintain the integrity of bacterial DNA.</p>

<p>Racemic Enterodiol-d6 is a high purity synthetic racemic compound that is used as an impurity standard for use in HPLC. The CAS number for Racemic Enterodiol-d6 is 104411-12-3. Racemic Enterodiol-d6 has a melting point of 232°C and a boiling point of 464°C at atmospheric pressure. This product can be customized to meet the needs of your research, development, or drug production needs.</p>

<p>Cetirizine impurity C is a potential impurity of cetirizine. It is used in the synthesis of cetirizine and as a drug substance. Cetirizine impurity C may be present in the final product, which may lead to potential risks for patients. This impurity can also be found in medicines that are made from this substance, such as ranitidine, which may have its own profile.</p>

<p>Tametraline is a medicinal compound that has been used in Chinese traditional medicine to treat tumors. It is an analog of protein kinase inhibitors and has shown potent anticancer activity in preclinical studies. Tametraline is an inhibitor of kinases, which are enzymes involved in the regulation of cell growth and division. It induces apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of these enzymes. Tametraline has also been found to be excreted in urine, indicating that it can be effectively metabolized by the human body. This compound holds great promise as a potential treatment for various types of cancer.</p>

<p>Nociceptin (1-7) is a drug product that is a natural, API impurity, and an impurity standard. It is used in research and development for the study of drug metabolism and pharmacopoeia for high purity standards in HPLC analysis. Nociceptin (1-7) is also synthesized as a synthetic compound with the CAS number 178249-42-8.</p>

<p>Descarboxy treprostinil is a synthetic drug product that is used as a research and development impurity standard. It has a purity of 98% or greater, and its CAS number is 101692-01-7. Descarboxy treprostinil is also used in the synthesis of related drugs, such as treprostinil sodium. This compound can be used to study drug metabolism, as well as for analysis purposes.</p>

<p>Nicotinic acid-13C1 is a nicotinic acid analog that is used to study the metabolism of nicotinic acid in humans. The 13C isotope is incorporated into the molecule, making it easier to detect and quantify using mass spectrometry. Nicotinic acid-13C1 can also be used as a high purity standard for HPLC analysis and as an impurity standard for pharmacopoeia testing. Nicotinic acid-13C1 can also be custom synthesized or obtained from natural sources such as yeast extract or synthetic sources such as 13C labeled acetone.</p>

<p>Please enquire for more information about 3-Des[2-(dimethylamino)ethyl] zolmitriptan acetonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Elbanizine is an anticancer agent that works by inhibiting kinase activity in cancer cells. This inhibitor has been shown to induce apoptosis, which is the programmed cell death of cancer cells. Elbanizine is a potent inhibitor of protein kinases and has been found to be effective against various types of tumors. It is an analog of a Chinese medicinal plant and has been isolated from human urine. Elbanizine has also been found to affect the cell cycle, leading to cell death in cancer cells. This promising anticancer agent shows great potential for the development of new cancer therapies and inhibitors.</p>

<p>Please enquire for more information about (3,5-Dimethyl-2-hexeno)-4-hydroxyphenone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-[(1E)-2-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl]diazenyl] balsalazide is a white to off-white solid that is soluble in water and acidic solutions. It has an impurity level of less than 0.5%. The melting point of 3-[(1E)-2-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl]diazenyl] balsalazide is approximately 195°C. This compound has been shown to have antibiotic activity against a variety of bacteria, including methicillin resistant Staphylococcus aureus (MRSA).</p>

<p>Please enquire for more information about 1,4-Bis(trichloromethyl)-2-chlorobenzene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine is a drug product with a CAS number of 70406-92-7. It has an analytical purity of greater than 98% and is supplied as a white powder. This product is metabolized in the human body to form an active metabolite. The chemical name for this drug product is ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine, which can be found in the pharmacopoeia under the name of 6′ amino 2,3′ dichlorobenzyl glycine.</p>

<p>Haloxyfop-d4 is an analog of the herbicide Haloxyfop that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a key role in cell division and growth. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. Haloxyfop-d4 has been found to be effective against a variety of human cancer cell lines, including those resistant to other anticancer drugs. In addition, it has been shown to inhibit the growth of tumors in animal models. This drug is metabolized in the liver and excreted in urine. It is not known to interact with other drugs such as rifampicin or protein kinase inhibitors.</p>

<p>Ergosterone is a potent anticancer agent that has been shown to induce apoptosis in various human cancer cell lines. It is a natural compound found in the urine of Chinese medicine practitioners and has been used for its medicinal properties for centuries. Ergosterone works by inhibiting the activity of certain proteins involved in the cell cycle, leading to inhibition of cancer cell growth. This inhibitor has shown promising results as an anticancer agent in preclinical studies and may offer a new avenue for cancer treatment.</p>

<p>Please enquire for more information about 2,3-Dihydroxypropyl valproate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Chlorpromazine N-oxide maleic acid salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Alpha-[4-(2-dimethylaminoethoxy)phenyl]stilbene (DS) is a synthetic, analytical standard that is used as an impurity in the manufacture of pharmaceutical products. DS is also sold as a reference material for HPLC and GC/MS analysis.</p>

<p>Rotigotine is a drug that belongs to the group of pharmaceutical formulations. It is an unlabeled drug that has been shown to be effective in the treatment of depression. Rotigotine may be administered through a transdermal patch or by iontophoresis, which is a technique used to administer drugs through the skin. The mechanism of action is not known, but it may involve the inhibition of monoamine reuptake and/or alteration of intracellular levels of catecholamines. Rotigotine sulfate has a high affinity for dopamine receptors and increases plasma concentrations of dopamine by inhibiting its reuptake into presynaptic neurons. This leads to increased concentrations of dopamine in synaptic clefts and an increase in postsynaptic receptor binding.</p>

<p>Dapsone N-β-D-glucuronide sodium salt is a drug product that is Custom synthesized for your research and development needs. It is available for sale as a white to off-white crystalline powder with a purity of 98%. Dapsone N-β-D-glucuronide sodium salt has CAS No. 54749-81-4, analytical, Metabolism studies, Drug development, Natural, Metabolite, pharmacopoeia, niche, Synthetic, Impurity standard and Research and Development. It is an HPLC standard in the form of a white to off-white crystalline powder with a purity of 98%.</p>

<p>1-(5-(4-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine (5FPP) is a drug product. It is an impurity standard for HPLC and analytical methods, as well as an API impurity. 5FPP is a synthetic compound that has been studied in metabolism studies. The metabolite of 5FPP is 1-(5-(4-fluorophenyl)-1H-pyrrolo[3,2,1-jk]thiazol-2(3H)-one).</p>

<p>Anilopam is an analog that has been identified as a potential anticancer agent. It works by inhibiting protein kinases, which are enzymes that play a crucial role in the growth and proliferation of cancer cells. Anilopam has been shown to inhibit the activity of several tumor-associated kinases, including those involved in cell cycle regulation and apoptosis. This medicinal compound has demonstrated potent antitumor activity in human cancer cell lines and has also shown promising results in preclinical studies. Anilopam is excreted primarily in urine and may have potential as a urinary biomarker for cancer diagnosis or monitoring treatment response. Its ability to inhibit kinase activity makes it a promising therapeutic option for the treatment of various types of cancers.</p>

<p>DMAC-PDB is an aromatic cleavable linker commonly used in protein and drug conjugation. It enables controlled release of payloads under specific chemical conditions.</p>

<p>Oxodesmosine is an analog of a protein found in Chinese urine that has shown promise as an anticancer agent. It works by inhibiting kinases, which are enzymes that play a key role in cancer cell growth and survival. Oxodesmosine has been shown to induce apoptosis, or programmed cell death, in tumor cells both in vitro and in vivo. This compound may be useful as a therapeutic agent for the treatment of various types of cancer in humans. Additionally, Oxodesmosine has been studied for its potential synergistic effects with other kinase inhibitors such as mirtazapine. Overall, Oxodesmosine represents a promising new avenue for the development of novel anticancer therapies.</p>

<p>Please enquire for more information about 3-Phenyl-4-(4-chlorosulfonylbenzyl)-5-methylisoxazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Linagliptin Impurity 18 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>