APIs for research and impurities
Active Pharmaceutical Ingredients (APIs) are the substances in drugs responsible for their therapeutic effects. In this section, you will find a wide variety of APIs intended for research use. These compounds are essential for the development, testing, and validation of new pharmaceutical formulations. CymitQuimica offers high-quality APIs to support research in drug discovery and development.
Subcategories of "APIs for research and impurities"
- Aminoacids and derivatives(12,316 products)
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- Natural and semi-synthetic antibiotics(6,307 products)
- Nitriles and Cyano Derivatives(3,068 products)
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- Nucleosides and Nucleotides(3,409 products)
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- β-Adrenergic Compounds(227 products)
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Found 58881 products of "APIs for research and impurities"
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2-Amino-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-4(5H)-thiazolone
CAS:2-Amino-5-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]-4(5H)-thiazolone is a structural analog of nitrite. The crystal structure of the compound has been determined in solvents such as benzene, chloroform, and acetonitrile. It is soluble in alkali and hydrochloric acid, but not in water. 2-Amino-5-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]-4(5H)-thiazolone crystallizes as a dimerized molecule with an acrylate group at each end. It can be prepared by reacting thiourea with copper (II) chloride. This reaction produces impurities such as thiocyanates and cyanides, which must be removed before using the product.Formula:C19H21N3O2SPurity:Min. 95%Molecular weight:355.46 g/molDesmethyl dehydro lercanidipine
CAS:Desmethyl dehydro lercanidipine is a metabolite of lercanidipine, an antihypertensive agent. Lercanidipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into cardiac muscle cells and vascular smooth muscle cells. The desmethyl form of lercanidipine has been shown to have anti-inflammatory effects in rats with experimental arthritis. It has also been shown to inhibit the production of inflammatory cytokines in lipopolysaccharide-stimulated human peripheral blood mononuclear cells.
Formula:C35H37N3O6Purity:Min. 95%Molecular weight:595.70 g/mol4',4'''-[(4'-Methyl-2'-propyl[2,6'-bi-1H-benzimidazole]-1,1'-diyl)bis(methylene)]bis[1,1'-biphenyl]-2-carboxylic acid
CAS:4',4'''-[(4'-Methyl-2'-propyl[2,6'-bi-1H-benzimidazole]-1,1'-diyl)bis(methylene)]bis[1,1'-biphenyl]-2-carboxylic acid is an analytical reagent that is used in research and development as a drug product impurity standard. This compound has been shown to be metabolized by cytochrome P450 1A1 and 2C8 to form 4-hydroxybenzoic acid and 4,4''-[(4'-methyl-2' propyl-[2,6']bi-1H-benzimidazol-1,1' diyl)bis(methylene)]bis[3-(4-hydroxyphenyl)-propionic acid], respectively. 4',4''-[(4'-Methyl-2' propyl-[2,6']bi-1Formula:C46H38N4O4Purity:Min. 95%Molecular weight:710.82 g/molDescyclopropyl lenvatinib
CAS:Descyclopropyl lenvatinib is a synthetic drug candidate that is being developed for the treatment of cancer. It is a metabolite of lenvatinib and has shown to have similar pharmacological activity, including inhibition of protein synthesis. Descyclopropyl lenvatinib also has been shown to inhibit the metabolism of other drugs, such as irinotecan, which may be due to its ability to inhibit cytochrome P450 enzymes.
Formula:C18H15ClN4O4Purity:Min. 95%Molecular weight:386.80 g/mol2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
CAS:2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole is a synthetic, impurity standard that is used in the synthesis of drug products. It has been shown to inhibit the metabolism of drugs and may be used as a marker for drug metabolism. This compound may also be used as a marker in analytical studies to assess the purity of a drug product. 2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole has not been evaluated for safety or efficacy.Formula:C15H15N3O2SPurity:Min. 95%Molecular weight:301.36 g/molAzithromycin impurity J
CAS:Azithromycin impurity J, also known as Azithromycin P-Toluenesulfonate, is an impurity of the drug azithromycin. It is an antibiotic that has been shown to be effective in the treatment of protozoal infections, cancer and parasites. Azithromycin impurity J has been shown to bind to DNA gyrase and topoisomerase IV enzymes, which are necessary for bacterial replication. Azithromycin impurity J is a protozoan inhibitor that acts by blocking the synthesis of RNA and DNA. This impurity binds to DNA gyrase and topoisomerase IV enzymes, which are necessary for bacterial replication. Azithromycin impurity J is a protozoan inhibitor that acts by blocking the synthesis of RNA and DNA.Formula:C30H58N2O9Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:590.79 g/mol(1R,1’R, 2’S)-2-Desmethyl cisatracurium besylate
CAS:Please enquire for more information about (1R,1’R, 2’S)-2-Desmethyl cisatracurium besylate including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C52H70N2O12Purity:Min. 95%Molecular weight:915.1 g/molBosentan impurity C
CAS:Bosentan impurity C is a stable crystalline compound that is soluble in organic solvents. It has been identified as an impurity of the drug bosentan, and has been found to be present in the drug at concentrations of up to 0.2%. Bosentan impurity C can be prepared by crystallization from an alkaline solution and can also be obtained as a salt form. The salt form is a dimer that consists of two bosentan molecules linked together by one oxygen atom. Bosentan impurity C is stable under normal conditions and does not undergo any changes when exposed to light or heat. This compound has shown no significant adverse effects on humans who have taken it, with no adverse effects on the kidney, liver, or lungs reported.Formula:C52H52N10O10S2Purity:Min. 95%Molecular weight:1,041.16 g/mol5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide
CAS:5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a drug product that was synthesized for research purposes. It is an analytical standard for HPLC and has not been approved for clinical use. 5-[(Hydroxylacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a compound with natural origin and has been classified as an API impurity. This synthetic drug product is custom synthesized to meet the requirements of pharmacopoeia standards.Formula:C16H20I3N3O8Purity:Min. 95%Molecular weight:763.06 g/molLoratadine epoxide
CAS:Loratadine is an antihistamine drug and its metabolite, loratadine epoxide, can be detected in the blood and urine of patients. Loratadine epoxide can be isolated from high-performance liquid chromatography (HPLC) with a spectrometer. The experimental method for the isolation of loratadine epoxide is to add diazomethane to a solution of loratadine in benzene. This experiment yielded a n-oxide that reacts with oxygen to form an aliphatic compound with a shift on the mass spectrum. This n-oxide has been found as an analyte in urine samples.Formula:C22H23ClN2O3Purity:Min. 95%Molecular weight:398.9 g/molAnastrozole dimer impurity - 65%
CAS:Anastrozole is an aromatase inhibitor used in the treatment of breast cancer. It is a synthetic drug and impurity standard for HPLC analysis, pharmacopoeia monograph, and synthetic drug development. This product is a mixture of two stereoisomers - the active form, 4-hydroxyanastrozole (4HA), and the inactive form, 4-oxo-anastrozole (4OA). The purity of this product is >99% with a melting point of 130°C.Formula:C30H31N9Purity:Min. 95%Molecular weight:517.63 g/mol4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide
CAS:4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide is a custom synthesis drug product. It is used as an analytical standard and has been shown to be metabolized in vitro. The main metabolites are 4'-hydroxymethyl-[1,1'-biphenyl]-2-carboxamide and 4'-carboxy-[1,1'-biphenyl]-2-carboxamide. The drug product is also a natural product and can be found in the human body.Formula:C14H12BrNOPurity:Min. 95%Molecular weight:290.16 g/molEnrofloxacin impurity C
CAS:Enrofloxacin impurity C is an impurity of enrofloxacin, a drug product. It is a metabolite of enrofloxacin, which has been studied for its effects on the metabolism and pharmacokinetics of this drug. Enrofloxacin impurity C specifically inhibits the activity of CYP3A4 and CYP2C8 in vitro. Enrofloxacin impurity C also has been shown to have niche applications in analytical chemistry as an impurity standard for HPLC analyses.
Formula:C19H23N3O3Purity:Min. 95%Color and Shape:PowderMolecular weight:341.4 g/molUlifloxacin acyl-β-D-glucuronide
CAS:Ulifloxacin acyl-β-D-glucuronide is an inhibitor of protein kinases that has been shown to induce apoptosis in cancer cells. This compound is a metabolite of ulifloxacin, a fluoroquinolone antibiotic used to treat urinary tract infections. Ulifloxacin acyl-β-D-glucuronide has potent anticancer activity and has been shown to inhibit the growth of tumor cells in vitro. This compound is an analog of other kinase inhibitors and has been extensively studied in Chinese hamster ovary (CHO) cells, where it was found to be effective against various types of cancer. Ulifloxacin acyl-β-D-glucuronide also possesses toxin-binding properties and may have potential as an anti-toxin agent.
Formula:C22H24FN3O9SPurity:Min. 95%Molecular weight:525.5 g/molVitamin B6 impurity 3
CAS:Vitamin B6 impurity 3 is a high purity synthetic compound with the CAS number 1385767-86-1. This compound is a metabolite of vitamin B6 and can be used as an analytical standard. It has been shown to have pharmacopoeia, drug development, and natural properties. Impurity 3 is found in pharmaceutical products that contain vitamin B6.Formula:C12H17NO3Purity:Min. 95%Molecular weight:223.27 g/molProbimane
CAS:Probimane is an anticancer drug that belongs to the class of kinase inhibitors. It is a synthetic analog of the Chinese herb, curcumol, and has been shown to inhibit the growth of tumor cells in vitro and in vivo. Probimane targets cyclin-dependent kinases (CDKs) and other protein kinases involved in cell cycle regulation, leading to apoptosis or programmed cell death. This drug has demonstrated potent activity against a range of human cancer cell lines, including breast, lung, and colon cancer. Probimane has also been found to be excreted in urine, making it a potential candidate for non-invasive monitoring of treatment efficacy.Formula:C21H34N6O6Purity:Min. 95%Molecular weight:466.5 g/mol3-Hydroxy darifenacin
CAS:Controlled Product3-Hydroxy darifenacin is a synthetic drug that is a prodrug of darifenacin. It has a niche application in the treatment of overactive bladder. This compound has been shown to be metabolized by CYP3A4 and CYP2D6. 3-Hydroxy darifenacin is an impurity standard for the HPLC assay of darifenacin and its metabolites.Formula:C28H30N2O3Purity:Min. 95%Molecular weight:442.5 g/molDidemethyl rizatriptan hydrochloride
CAS:Didemethyl rizatriptan hydrochloride is a potent anticancer agent that belongs to the indirubin analog family. It acts as a selective inhibitor of various kinases, including cyclin-dependent kinase (CDK), glycogen synthase kinase-3β (GSK-3β), and casein kinase 1 (CK1). This drug has been shown to induce apoptosis in various human cancer cell lines, including breast, prostate, and colon cancers. Didemethyl rizatriptan hydrochloride has also demonstrated significant tumor growth inhibition in animal models of cancer. Moreover, this drug can be detected in urine samples of Chinese patients with cancer who have received treatment with this inhibitor. Overall, didemethyl rizatriptan hydrochloride shows great promise as an effective protein kinase inhibitor for the treatment of cancer.Formula:C13H16ClN5Purity:Min. 95%Molecular weight:277.75 g/mol1,4-Bis(trichloromethyl)-2-chlorobenzene
CAS:Please enquire for more information about 1,4-Bis(trichloromethyl)-2-chlorobenzene including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C8H3Cl7Purity:Min. 95%Molecular weight:347.3 g/molZanapezil
CAS:Zanapezil is a human and Chinese analog of mirtazapine that has been studied for its potential anticancer properties. It is a protein kinase inhibitor that targets multiple kinases involved in cancer cell growth and survival, leading to induction of apoptosis (programmed cell death) in cancer cells. Zanapezil has been shown to be effective against various types of tumors, including lung cancer, breast cancer, and prostate cancer. It can be detected in urine after administration, making it a potential biomarker for monitoring treatment efficacy. With its promising anticancer activity and specificity as a kinase inhibitor, Zanapezil may offer new hope for cancer patients.Formula:C25H32N2OPurity:Min. 95%Molecular weight:376.5 g/mol
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