APIs for research and impurities

Roxithromycin impurity E is a metabolite of roxithromycin. It is a yellow powder with a melting point of about 130°C and a molecular weight of 226.14g/mol. Roxithromycin impurity E has been shown to be an inhibitor of CYP3A4 and CYP2D6, as well as an inducer of CYP1A2. This impurity can be used for the research and development of roxithromycin, as well as production of analytical standards for HPLC analysis.

Gimatecan is a cycle-specific inhibitor that targets kinases and proteins involved in cancer cell growth. It is a medicinal compound that has been shown to be effective against various types of human cancers. Gimatecan works by inhibiting the activity of protein kinases, which are enzymes that promote cell division and proliferation. This inhibition leads to apoptosis, or programmed cell death, in tumor cells. Gimatecan has been tested extensively in Chinese hamster ovary cells and has demonstrated potent anticancer activity. The compound is excreted primarily through urine and has shown promising results as an anticancer agent in preclinical studies.

L-Isoleucine orlistat is a drug product that is an analytical standard and a natural product. It is used in research and development for the study of drug metabolism, and as an impurity standard for synthetic L-isoleucine. L-Isoleucine orlistat has CAS number 1072902-75-0 and Impurity Standard Number (ISN) 910.
L-Isoleucine orlistat is not a registered active pharmaceutical ingredient (API). It can be custom synthesized to meet the requirements of a particular application, such as high purity, pharmacopoeia grade, or USP HPLC grade.

Ros 234 is a dioxalate salt of rosiglitazone, and is an anti-cancer agent that inhibits the growth of cancer cells. Ros 234 has been shown to inhibit inflammatory conditions such as asthma, rheumatoid arthritis, and colitis. It also modulates immune and autoimmune responses.

Deschloro amlodipine is a drug that is used for the treatment of high blood pressure. It belongs to a group of drugs called calcium channel blockers. Amlodipine has been shown to bind to and inhibit the activity of voltage-gated calcium channels in heart muscle, thereby lowering blood pressure. Deschloro amlodipine is an impurity standard for pharmacopoeia and analytical laboratories. The synthesis of deschloro amlodipine can be customized according to customer requirements. This product will be shipped as soon as possible after purchase.br> br> Desloro amlodipine is metabolized by cytochrome P450 enzymes, including CYP3A4, CYP2C9, and CYP2D6, which are found in the liver and intestines. These enzymes convert desloro amlodipine into two metabolites: 4-hydroxyamlodipine and 4

Olaparib impurity 14 is a metabolite of olaparib. Olaparib is a drug used to treat cancer by inhibiting the activity of PARP1, an enzyme that repairs DNA damage. This impurity is a compound that can be synthesized in high purity and quality with a custom synthesis service. It has been shown to have niche applications in pharmacopoeia, drug development, and analytical studies.

7β,25-Dihydroxycholesterol is a steroid precursor that is synthesized in the liver and is converted to other steroid hormones. It has been shown to be important in immune function and as a regulator of cholesterol metabolism. In addition, 7β,25-Dihydroxycholesterol can bind to follicle cells and immune cells, activating signalling pathways. This compound has been shown to have an immunosuppressive effect on the humoral immune response by blocking antibody production. The receptor for 7β,25-Dihydroxycholesterol has been identified as GPER1. Knockout mice studies have shown that this receptor plays a role in regulating the number of plasma cells and oxysterols.