Amino Acids (AA)

<p>Applications 3-Chloro-3-methyl-1-butyne is a propargyl chloride used to alkylate methanol, ethanol, ammonia and amines to the corresponding propargylic ether and amines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hennion, G.F. et al.: J. Org. Chem., 34, 1319 (1969); Joshi, R. et al.: Tetrahedron, 49, 2353 (1993);<br></p>

<p>Applications 1-[(4R,5R)-N2-(10,12-Dimethyl-1-oxotetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 is an intermediate in the synthesis of Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall.<br>References Leonard, W. R., et al.: J. Org. Chem., 72, 2335 (2007);<br></p>

<p>Applications 2-amino-N-methylpyridine-4-carboxamide (cas# 1211295-76-9) is a useful research chemical.<br></p>

<p>Applications 2-chloro-4-methylnicotinamide (cas# 152362-01-1) is a useful research chemical.<br></p>

<p>Applications 4-Hydroxy-3-(3-methoxybenzoyl)benzoic Acid Methyl Ester is used in the synthetic preparation of 9-oxoxanthen-2-carboxylic acids.<br>References Graham, R. &amp; Lewis, J.: J. Chem. Soc. Perk. T. 1, No vol. given, 876 (1972-1999)<br></p>

<p>Applications Dalapon-methyl<br></p>

<p>Applications 2-iodo-6-methylbenzoic acid (cas# 54811-50-6) is a useful research chemical.<br></p>

<p>Applications (4-Chloro-3-methoxyphenyl)hydrazine is used as a reactant in the preparation of N-phenylpyrazolylamine and N-pyridylpyrazolylamine derivatives as insecticides, herbicides, and fungicides.<br>References Uneme, H., et al.: Jpn. Kokai Tokkyo Koho (1996), JP 08208620 A 19960813<br></p>

<p>Applications 5-(1-Methyl-1H-pyrazol-4-yl)-2-pyrimidinemethanamine is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Chloro-2-methyl-2-butanol (cas# 1985-88-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Benzyl[2-(4-methoxyphenyl)ethyl]amine Hydrochloride, is the salt form of Benzyl[2-(4-methoxyphenyl)ethyl]amine (B285040), which is synthesized in the study of heavier group 2 metals for the intermolecular hydroamination.<br>References Barrett, A., et al.: J. Am. Chem. Soc., 131, 12906 (2009)<br></p>

<p>Applications 4-Methoxyphenol-2,3,5,6-d4,OD (CAS# 126840-02-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Methylnapththalene is a carcinogenic polycyclic aromatic hydrocarbon (PAH) that can be measured using 1-hydroxypyrene in urine as a biomarker. This compound is a contaminant of emerging concern (CECs)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moen, B.E., et. al.: Occup. Environ. Med., 53, 692 (1996)<br></p>

<p>Applications Dl-tert-leucine<br></p>

<p>Applications 1-(4-Methoxyphenyl)ethanol (cas# 3319-15-1) is a useful research chemical.<br></p>

<p>Applications 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-inden-5-ol (cas# 133-21-1) is a useful research chemical.<br></p>

<p>Applications 7-Benzyloxy-4-hydroxy-6-methoxyquinoline Hydrochloride is used in the preparation of quinolines and quinazolines as inhibitors of c-Met and other tyrosine kinases and therapeutic uses against proliferative diseases.<br>References Bannen, L., et al.: PCT Int. Appl. (2005), WO 2005030140 A2 20050407.<br></p>

<p>Applications Dihydro-4-methyl-2(3H)-furanone (cas# 1679-49-8) was identified as an aroma contributing compound in a flavour profiling of Wild Harenna coffee beans.<br>References Ascrizzi, R., et al.: Eur. Food Res. Technol., 246, 643 (2020)<br></p>

<p>Applications 2-(1-Methyl-1H-pyrazol-4-yl)ethanamine (cas# 796845-58-4) is a useful research chemical in the development of DNA-compatible methodology for generating novel highly functionalized imidazoles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Geigle, S. N., et al.: Org. Lett., 21, 9001 (2019)<br></p>

<p>Applications 2-[2-(2-Aminophenoxy)ethoxy]-4-methyl-benzenamine (cas# 96331-95-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Isotope labelled 3-Methoxy-5-methylaniline (M263310) is a aniline derivative used in the preparation of sulphonamides and aryl amines as antitubercular agents.<br>References Rajvaidya, S., et al.: J. Institut. Chem., 74, 79 (2002); Haworth, R..D., et al.: J. Chem. Soc. Transact., 123, 2982 (1932);<br></p>

<p>Applications 4-Chloro-6-fluoro-2-methylquinazoline<br></p>

<p>Applications 4-Chloro-2-methoxypyridine is a reagent in the preparation of cyclopalladated ferrocenylimines as efficient catalysts for the preparation of arylboronate esters.<br>References Wang, L., et al.: Adv. Synth. Catal., 352, 2002 (2010);<br></p>

<p>Applications 1-Iodo-3,4-methylenedioxybenzene is an iodinated benzodioxole used in the preparation of various biologically active compounds such as the antiviral and antitumor agents.<br>References Ikeda, M. et al.: Chem. Pharmac. Bull., 47, 983 (1999);<br></p>

<p>Applications 4-methoxybenzene-1,2-diol (cas# 3934-97-2) is a useful research chemical.<br></p>

<p>Applications 2-Bromo-3-methoxy-6-nitropyridine (cas# 76066-07-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 8,9-Dihydro-2-methyl-9-(4-methylphenyl)-8-oxo-7H-purine-6-carboxamide-d7 is a compound useful in organic synthesis.<br></p>

<p>Applications methyl 2-hydroxy-4-methylpentanoate (cas# 40348-72-9) is a useful research chemical.<br></p>

<p>Applications 7-Bromo-2-methyl-2H-indazole-3-carbonitrile is an indazole derivative.<br></p>

<p>Applications 4-Methylcyclohexanemethanol is patented for use as an ingridient of air fresheners. It can also be used to synthesize thiazolidinedione (2,4-thiazolidinedione, T344250) derivatives as 15-PGDH inhibitors.<br>References Wu, Y., et al.: Bioorg. Med. Chem., 18, 1428 (2010);<br></p>

<p>Applications 3-(3-Ethoxy-4-methoxyphenyl)propionic-2,2,3,3-d4 Acid (CAS# 1398065-51-4) is a useful isotopically labeled research compound. This compound can be prepared as an FSH agonist that can be used to treat fertility disorders.<br>References Yu, H.et.al., U.S. Pat. Appl. Publ., (2015);<br></p>

<p>Applications Intermediate in the production of DMEQ-TAD<br></p>

<p>Applications N-Boc-(p-Aminobenzoyl)-L-glutamic Acid Dimethyl Ester-13C5 is an intermediate used in the synthesis of Folic Acid-13C5 (F680303), which is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),<br></p>

<p>Applications N-(2-Methoxyethyl)-2,6-xylidine is an intermediate used in the synthesis of Dimethachlor Ethane Sulfonic Acid Sodium Salt (D460283), which is a pesticide metabolite pollutant found in groundwater, surface water, and wastewater.<br>References Huntscha, S., et al.: J. Chromatogr. A, 1268, 74 (2012); Reemtsma, T., et al.: J. Chromatogr. A, 1271, 95 (2013);<br></p>

<p>Applications 2-methyl-2-(morpholin-4-yl)propanoic Acid hydrochloride (cas# 375397-37-8) is a useful research chemical.<br></p>

<p>Applications 2-Ethyl-5-oxo-hexanoic Acid 1-Methylethyl Ester (cas# 1346599-42-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(Methoxy-d3)-3-(2-methylpropyl)pyrazine is an intermediate used in the preparation of 2-methoxy-3-alkylpyrazines and their deuterated isotopologues.<br>References Schmarr, H. G., et al.: J. Label. Compds and Radiopharm., 54, 438 (2011); Gerritsma, D. A., et al.: J. Label. Compds. Radiopharm., 46, 243 (2003)<br></p>

<p>Applications 6-Dodecanoate-1,4-anhydro-D-glucitol-d23 is the isotopic form of 6-Dodecanoate-1,4-anhydro-D-glucitol (D494710). 6-Dodecanoate-1,4-anhydro-D-glucitol is used in the synthetic preparation of nonionic surfactant.<br>References Giacometti, J. et al.: J. Agr. Food Chem., 44, 3950 (1996)<br></p>

<p>Applications L-Leucine-3,3-d2 (CAS# 362049-59-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-methyl-3-oxo-2,3-dihydro-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid (cas# 862273-50-5) is a useful research chemical.<br></p>

<p>Applications 3-Chloro-6-fluoro-2-methoxybenzoic acid (cas# 1781848-13-2) is a useful research chemical.<br></p>

<p>Applications L-Isolecucine 7-Amido-4-methylcoumarin Trifluoroacetate Salt is an enzyme substrate. It can be used as analytical reagent use and in biological study of detection of yeasts and/or molds in a food sample using aminopeptidase substrates containing a fluorescent marker.<br>References Chen, C., et al.: PCT Int. Appl., WO 9827223 A1 19980625 (1998)<br></p>

<p>Applications N-Methylcarbonyl-2-chloroacetamidrazone (cas# 155742-64-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Chloro-6-methylisoquinoline (cas# 209286-73-7) is a useful research chemical.<br></p>

<p>Applications D-Glucosamine-2-N-sulfate sodium salt (cas# 38899-05-7) is a useful research chemical.<br></p>

<p>Applications D-Serine benzyl ester hydrochloride (cas# 151651-44-4) is a useful research chemical.<br></p>

<p>Applications 2’-C-Methyl-2’,3’,5’-tri-O-benzoylcytidine (cas# 640725-69-5) is a compound useful in organic synthesis.<br></p>

<p>Applications Fmoc-Glycinol is an Fmoc protected amino alcohol. Fmoc-Glycinol is used in the preparation of amphiphilic lactosides.<br>References Miura, Y. et al.: Carb. Res., 289, 193 (1996); Hatanaka, Y. et al.: Chem. Pharm. Bull., 44, 1111 (1996);<br></p>

<p>Applications δ-Valerolactam is a useful synthetic intermediate. It is an intermediate used to synthesize Cenicriviroc (C256550), an experimental drug candidate for the treatment of HIV infection. It is also a starting material for a new route to hexahydrojulolidines, using intramolecular 1,4-cycloaddition.<br>References Potts, K., et al. J. Org. Chem., 58, 5040 (1993); Klibanov, O., et al.: Curr. Opinion Invest. Drugs, 11, 940 (2010);<br></p>

<p>Applications N-Methylpiperidinyl-2-methyl Benzilate (cas# 94909-90-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(4-Fluorophenyl)-1-methyl-1H-benzo[d]imidazole has been used as an electrolyte additive used to enhance the performance of dye-sensitized TiO2 solar cells.<br>References Kusama, H., Arakawa, H.: J. Photochemistry Photobiology A., 162, 441 (2004)<br></p>

<p>Applications N-Methyl-d3-form-d1-amide (CAS# 110505-55-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications 5-Hydroxy-7-methoxy-2-phenyl-4H-chromen-4-one (cas# 520-28-5) is a useful research chemical.<br></p>

<p>Applications A benzothiophene having antiallergic activity.<br>References Showalter, H.D., et al.: J. Med. Chem., 31, 1527 (1988), Sugiyama, H., et al.: Chem. Pharm. Bull., 55, 613 (2007),<br></p>

<p>Applications DL-4-Hydroxyphenyl-2,6-d2-alanine-2-d1 (CAS# 73036-42-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Ethyl 4-Methyl-1-(1-phenylpropan-2-yl)-1H-pyrrole-2-carboxylate is an intermediate used in the synthesis of 4-Methyl-1-(1-phenylpropan-2-yl)-1H-pyrrole-2-carboxylic Acid (M339120), which is an impurity of the drug Amphetamine (A634248).<br></p>

<p>Applications 1-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)-2-methoxyethanone has been used as a reactant in the synthesis of metoprolol (M338790) metabolites.<br>References Shetty, H.U., Nelson, W.L.: J. Med. Chem., 31, 55 (1988)<br></p>

<p>Applications 4-Methyl-1H-imidazole-5-carboxylic Acid is used in preparation of Cyclohexyl Benzamide compounds for treatment of type II diabetes. Also, used in preparation of Triazolylphenyl substituted Amides as apoptosis signal-regulating kinase inhibitors.<br>References Hu, Z., et al.: PCT Int. Appl.,(2018); Corkey, B., et al.: U.S., (2015);<br></p>

<p>Applications 2-amino-4-fluoro-3-methylbenzoic acid (cas# 129833-28-9) is a useful research chemical.<br></p>

<p>Applications N-(2,4-Dinitro-5-fluorophenyl)-L-valinamide is used in the synthesis of chiral variants of Marfey’s reagent. It is also used in the preparation of phaeofungin from Phaeosphaeria.<br>References Bhushan, R. et al.: Acta. Chrom., 20, 329 (2008); Singh, S. et al.: J. Nat. Prod., 76, 334 (2013);<br></p>

<p>Applications 2-Methoxytoluene-alpha,alpha,alpha-d3 (CAS# 258832-47-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications (2S)-2-Hydroxy-2-methylbutanoic Acid is a useful building block for organic synthesis.<br></p>

<p>Applications Methyl 2-Amino-5-methylthiophene-3-carboxylate is used as a starting reagent in the synthesis of Thieno[2,3-b]Pyridinones and 4-Hydroxy-6-oxo-6,7-dihydro-thieno[2,3-b]pyridine derivatives, compounds that act as cytoprotectants and inhibitors of the N-Methyl-D-aspartate (NMDA) receptor.<br>References Buchstaller, H., et al.: J. Med. Chem., 49, 864 (2006); Hwang, K., et al.: Arch. Pharm. Res., 24, 270 (2001)<br></p>

<p>Applications Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus.<br>References Wang, R., et al.: J. Mol. Catal. B. Enz., 56, 131 (2009); Springhorn, C. et al.: J. Clin. Endocrinol. Metab., 97, 4640 (2012); Hashimoto, K. et al.: J. Clin. Endocrinol. Metab., 97, 3016 (2012); Avelange, M. et al.: Plant. Phys., 94, 1157 (1990); Cramer, C. et al.: J. Chem. Soc., 115, 5745 (1993);<br></p>

<p>Applications N-Boc-4-aminophenethylamine is used in the preparation of N-phenylethylindole carboxamides as SAR study of allosteric modulators of CB1 receptors.<br>References Piscitelli, F., et al.: J. Med. Chem., 55, 5627 (2012)<br></p>

<p>Applications D-4-Hydroxyphenyl-d4-alanine-2,3,3-d3 (CAS# 1426174-46-0) is a useful isotopically labeled research compound.<br></p>