Amino Acids (AA)

<p>Applications N-Benzyloxycarbonyl L-Threonine Amide O-Methanesulfonate (cas# 80082-51-5) is a compound useful in organic synthesis.<br></p>

<p>Applications Pipecolic acid is involved in synaptic transmission in the central nervous system.<br>References Nomura Y., et al.: Neurochem. Res., 6, 391 (1981),<br></p>

<p>Applications Sinorphan is an inhibitor of angiotensin-converting enzyme and neutral endopeptidase.<br>References Sulpizio, A.C., et al.: J. Pharmacol. Exp. Therap., 209, 1141 (2004); Takeda, Y., et al.: J. Hyper., 18, 927 (2000); Monteil, T., et al.: Syn. Comm., 31, 211 (2001);<br></p>

<p>Applications N-Methylformanilide is an aromatic reagent used in the synthesis of dye-sensitized solar cells. Also used in the synthesis of potent tyrosinase inhibitors.<br>References Meyer, T et al.: J. Org. Chem., 77, 3704 (2012); Nihei, K. et al.: Bioorg. Med. Chem. Lett., 14, 681 (2004);<br></p>

<p>Applications L-Glutamic acid dibenzyl ester 4-toluenesulfonate<br></p>

<p>Applications 2-(6-methoxynaphthalen-2-yl)propanenitrile (cas# 86603-94-3) is a useful research chemical.<br></p>

<p>Applications N-Methyl-p-toluenesulfonamide is an intermediate used in the synthesis of vicinal haloamino ketone derivative.<br>References Sun, H., et al.: Chem. Biol. Drug Design, 75, 269 (2010)<br></p>

<p>Applications D-Tyrosine, the stereoisomer to L-Tyrosine (T899975), is an amino acid used in various organic syntheses for antibiotics. It is used in the synthesis of (-)-anisomycin, as well as BATSI (boronic acid transition state inhibitors) which act on β-lactamases. It has also been studied as an inhibitor of microbial growth on surfaces, reducing microbial attachment to hydrophillic glass and hydrophobic polypropylene surfaces.<br>References Li, Ji. et al.: Chin. Chem. Lett., 23, 647 (2012); Xu, H. et al.: Water Res., 45, 5796 (2011); Ke, W. et al.: Antimicrob. Agents Chemother., 55, 174 (2011);<br></p>

<p>Applications L-Hydroxyprolylglycine_x000D__x000D (cas# 7672-35-7) is a useful research chemical.<br></p>

<p>Stability Air Sensitive, Moisture Sensitive<br>Applications (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate hydrate (cas# 41468-25-1) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications β-Methylamino-L-alanine Hydrochloride is a useful intermediate in the synthesis of β-N-methylamino-L-alanine and other amino acid derivatives.<br>References Arevalo-Garcia, E. B., et al.: Tetrahedron Lett., 55, 2335 (2014); Sagiyan, A. S., et al.: Hayastani Kimiakan Handes, 61, 424 (2008); Sagiyan, A. S., et al.: Russ. Chem. Bull., 46, 483 (1997)<br></p>

<p>Applications N-Methyl-N-nitroso-1-hexadecanamine is a compound found in a wide range of cosmetic products and cleaning emulsions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kamp, E.. et al.: Food. Chem. Toxicol., 29, 203 (1991); Lalljie, S. P. D., et al.: Adv. Mass. Spec., 14, 33790 (1998); Abidi, S.L., et al.: J. Chroma., 324, 209 (1985);<br></p>

<p>Applications 2-Methoxyphenylsulfate is used in the analysis of alkylsulfatases and their kinetics.<br>References Bateman, T. et al.: Biochem. J., 236, 401 (1986);<br></p>

<p>Applications 6-Methyl-1,4-naphthoquinone (cas# 605-93-6) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Methyl-N-nitroso-1-octadecylamine was found to present in various hair-care products when investigated through thermal energy analyzer.<br>References Morrison, J.B., et al.: Food. Chem. Toxicol., 21, 69 (1983); Rainey, W.T., et al.: Biomed. Mass. Spec., 5, 395 (1978);<br></p>

<p>Stability Moisture Sensitive<br>Applications 3-Glycidoxypropyltrimethoxysilane (cas# 2530-83-8) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications (S)-(+)-2-Methylbutyric Acid is a chiral starting reagent used in various synthetic preparations.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Neves, F., et al.: Beilstein. J. Org. Chem., 7, 1504 (2011); King, A.M., et al.: J. Medn. Chem., 54, 6432 (2011); Ferrarni, A., et al.: Chirality., 26, 9 (2011);<br></p>

<p>Applications L-Valine (1-13c, 99%) (cas# 81201-85-6) is a useful research chemical.<br></p>

<p>Applications 4-Methoxyresorcinol (cas# 6100-60-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Hydroxy-3-methylpyridine, is an building block used in the chemical synthesis of various pharmaceutical and biologically active compounds. It is an intermediate for the synthesis of second generation agonist of the orphan G-protein coupled receptor GPR119, for the treatment of diabetes.<br>References Graeme, S., et al.: Bioorg. Med. Chem. Lett., 22, 1750 (2012);<br></p>

<p>Stability Hygroscopic<br>Applications endo-9-Methyl-9-azabicyclo[3.3.1]nonan-3-amine Acetate is an impurity of Granisetron HCl (G780000), a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy<br>References Kilpatrick, G.J., et al.: Nature, 330, 746 (1987), Durig, T., et al.: J. Pharm. Sci., 86, 1092 (1997), Yuasa, H., et al.: Chem. Pharm. Bull., 44, 1361 (1996),<br></p>

<p>Stability Hygroscopic<br>Applications 3-Methyl-2-oxovaleric acid calcium salt (cas# 66872-75-1) is a useful research chemical.<br></p>

<p>Applications 3-Mercapto-3-methylbutyl formate is one of the major odor-active thiol in pan-roasted white sesame seeds.<br>References Czerny, M., et al.: J .Agric. Food Chem., 47, 695 (1999), Steinhaus, M., et al.: Eur. Food Res. Technol., 226, 45 (2007), Tamura, H., et al.: Agric. Food Chem., 2010, 58, 7368 (2010),<br></p>

<p>Applications 3-Chloromethyl-5-methylpyridine is an intermediate in the synthesis of Rupatadine (R701650).<br>References Merlos, M., et al.: Pharmacol. Exp. Therap., 280, 114 (1997), Bell, I., et al.: J. Med. Chem., 41, 2146 (1998),<br></p>

<p>Applications 5-Methyl-5-phenylhydantoin is a reactant for synthesis of beta-amino alcohols as inhibitors of anti-tubercular target N-acetyltransferase, chlorohydantoins and specific MMP inhibitors.<br>References Fullam, E., et al.: Bioorg. Med. Chem. Lett., 21, 1185 (2011); Whitehead, D., et al.: Tetrahedron Lett., 50, 3 (2009); Chollet, A., et al.: Bioorg. Med. Chem., 10, 531 (2002)<br></p>

<p>Applications VINYLTRIS(2-METHOXYETHOXY)SILANE (cas# 1067-53-4) is a useful research chemical.<br></p>

<p>Applications 4′-Methylpropiophenone is a chemical reagent used in electrocarboxylation reactions.<br>References Zhang, K. et al.: Chin. J. Chem., 28, 509 (2010); Zhao, S. et al.: Tetra. Lett., 52, 2702 (2011);<br></p>

<p>Applications 7-Chloro-8-methylquinoline (cas# 78941-93-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Bromo-6-methyl-3H-1,3-benzodiazole<br></p>

<p>Applications 1,2:4,5-bis-O-(1-Methylethylidene)-β-D-Fructopyranose is a reagent in the synthesis of antibacterial/antifungal monosaccaride esters. Also used in the synthesis of antihyperlipidemic novel compounds involving glycosyl fructose derivatives.<br>References Shen, Y. et al.: Molecules, 17, 8661 (2012); Tiwari, P. et al.: Bioorg. Med. Chem. Lett., 16, 6028 (2006);<br></p>

<p>Stability Air Sensitive<br>Applications A metabolite of Methyl Isocyanate.<br>References Slatter, J. G., et al.: Chem. Res. Toxicol., 4, 157 (1991),<br></p>

<p>Applications Ethylenediaminetetraacetic Acid-d16 (CAS# 203805-96-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications L-Aspartic Acid is a non-essential amino acid found in food sources. L-Aspartic Acid is one of the 20 proteinogenic amino acids; the building blocks of proteins. Its conjugate base L-aspartate is an excitatory neurotransmitter in the central nervous system.<br>References Ager, D.J. et al.: J. Mol. Catal. Enzym., 11, 199 (2001); Velisek, J. et al.: Cze. J. Food. Sci., 24, 1 (2006); Nagahama, M. et al.: Cell Tiss. Res., 318, 483 (2004);<br></p>

<p>Applications L-Lysine-3,3,4,4,5,5,6,6-d8 Dihydrochloride, is the labelled L-Lysine, a naturally occurring amino acid which is used in the labelling of human bone marrow mesenchymal stem cells for analysis.<br>References Rocha, B. et al.: J. Prot. Res., 11, 5350 (2012); Kumar, D. et al.: Polym. J., 45, 160 (2013);<br></p>

<p>Applications 8-Chloro-4-hydroxy-2-methylquinoline (cas# 5236-87-3) is a useful research chemical.<br></p>

<p>Impurity Verapamil EP Impurity K<br>Applications (Verapamil EP Impurity K)<br></p>

<p>Applications A protected glutamic acid for use in peptide synthesis.<br>References Takahashi, M., et al.: J. Exp. Biol., 200, 401 (1997), Michaelis, E., et al.: Prog. Neurobiol., 54, 369 (1998), Koch, H., et al.: Mol. Pharmacol., 55, 1044 (1999), O'Kane, R., et al.: J. Biol. Chem., 274, 31891 (1999),<br></p>

<p>Applications An antibody agent.<br>References Rowell, F. J., et al.: Immunochemistry, 13, 891 (1976),<br></p>

<p>Applications Protected 1,2-Phenyldiamine, an intermediate in the synthesis of histone deacetylase agents and antitumor agents.<br>References Andrews, D., et al.: Bioorg. Med. Chem. Lett., 18, 2580 (2008), Mahboobi, S., et al.: J. Med. Chem., 52, 2265 (2009),<br></p>

<p>Applications N-Acetyl-L-phenylalanine is an protected analogue of L-Phenylalanine (P319415), an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of Aspartame.<br>References Sriram, S., et al.: J. Med. Chem., 56, 2540 (2013); Parker, B.M., et al.: J. Biotech., 155, 396 (2011);<br></p>

<p>Applications Labelled Tiopronin. It is used as antidote against heavy metal poisoning; hepatoprotectant; mucolytic.<br>References Capasso, F., et al.: Agents Actions, 11, 741 (1981), Amor, B., et al.: Arthritis Rheum., 25, 698 (1982), Ichida, F., et al.: J. Int. Med. Res., 10, 325 (1982),<br></p>

<p>Applications L-Alanine-d7 (CAS# 74280-71-0) is a useful isotopically labeled research compound.<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-chloro-5-fluoro-2-methoxypyrimidine (cas# 1801-06-5) is a useful research chemical.<br></p>

<p>Applications 2-Methylresorcinol (cas# 608-25-3) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Hydroxyprolines are valuable chiral building blocks for organic synthesis of pharmaceuticals. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.<br>References Lawrence, C., et al.: Biochem. J., 313, 185 (1996), Mori, H., et al.: J. Bacteriol., 179, 5677 (1997), Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (2001),<br></p>