Amino Acids (AA)

<p>Applications 1,3,5-Trimethoxy-2-methylbenzene AldrichCPR (cas# 14107-97-2) is a useful research chemical.<br></p>

<p>Applications 4-Methylmorpholine is used in the synthesis of novel and selective TYK2 inhibitors, used in the treatment of inflammatory diseases. Also used in the preparation of cathespin K inhibitors which are highly selective.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liang, J. et al.: Eur. J. Med. Chem., 67, 175 (2013); Yuan, X. et al.: Org. Biomol. Chem., 11, 5847 (2013);<br></p>

<p>Applications 4-Bromo-6-methyl-3H-1,3-benzodiazole<br></p>

<p>Applications 2-Hydroxy-5-methylpyridine (cas# 1003-68-5) is a useful compound for organic synthesis. In particular it has been used for the diastereoselective preparation of cyclobutane-fused pyridinyl sulfonyl fluorides.<br>References Liu, J., et al.: Org. Biomol. Chem., 18, 4019 (2020)<br></p>

<p>Applications β-Alanine-13C3,15N is the isotope labeled analogue of β-Alanine (A637320), which is a naturally occurring beta amino acid. β-Alanine is formed in vivo by the degradation of Dihydro Uracil (D449990) and Carnosine. β-Alanine is also the rate-limiting precursor of Carnosine, as a result supplementation with β-Alanine increases the concentration of Carnosine in muscles.<br>References Derave, W. et al.: J. Appl. Physiol., 103, 1736 (2007); Xia, J.-F. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 977, 1930 (2009); Artioli, G.G. et al.: Med. Sci. Sports Exer.,42, 1162 (2010);<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-chloro-5-fluoro-2-methoxypyrimidine (cas# 1801-06-5) is a useful research chemical.<br></p>

<p>Applications (E)-Ethyl 4-Bromo-3-methyl-2-butenoate (cas# 51318-62-8) is a compound useful in organic synthesis.<br></p>

<p>Applications A synthetic intermediate.<br>References Blakemore, R., et al.: Eur. J. Med. Chem., 22, 91 (1987),<br></p>

<p>Applications Methyl 4-Methyl-3-hydroxybenzoate is used in the preparation of potent antimalarial agents. Also used in the preparation of aromatic inhibtors of anthranilate synthase.<br>References Fattorusso, C. et al.: J. Med. Chem., 51, 1333 (2008); Payne, R. et al.: Org. biomol. Chem., 3, 3629 (2005);<br></p>

<p>Applications 2,6-Di-(tert-butyl-d9)-4-methylphenol-3,5-d2,OD (CAS# 64502-99-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Methoxyphenol-3,4,5,6-d4 (CAS# 7329-52-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Acetyl-S-(3-hydroxypropyl)-L-cysteine Dicyclohexylamine Salt (unlabelled) (CAS# 14369-42-7) is a useful research compound.<br></p>

<p>Applications 5,6-Dihydro-5-methyluridine (cas# 23067-10-9) is a useful research chemical.<br></p>

<p>Applications Tetrahydro-5-methyl-2-furanol is an intermediate in synthesizing 2,3-Dihydro-2-methylfuran (D447355), which is a general reagent used in next generation of biofuels. Dihydrofuranyl derivative.<br>References Simmie, J. et al.: J. Phys Chem., 116, 4528 (2012);<br></p>

<p>Applications Intermediate in transsulfuration whereby the mammal transfers the sulfur of methionine via homocysteine to cysteine.<br>References Prochazka, Z., et al.: Collection Czechoslov. Chem. Commun., 45, 1982 (1980), Yorek, M.A. &amp; Spector, A.A.: Prog. Clin. Biol. Res., 179, 361 (1985)<br></p>

<p>Applications 5-Methyl-5-phenylhydantoin is a reactant for synthesis of beta-amino alcohols as inhibitors of anti-tubercular target N-acetyltransferase, chlorohydantoins and specific MMP inhibitors.<br>References Fullam, E., et al.: Bioorg. Med. Chem. Lett., 21, 1185 (2011); Whitehead, D., et al.: Tetrahedron Lett., 50, 3 (2009); Chollet, A., et al.: Bioorg. Med. Chem., 10, 531 (2002)<br></p>

<p>Applications 1,2:4,5-bis-O-(1-Methylethylidene)-β-D-Fructopyranose is a reagent in the synthesis of antibacterial/antifungal monosaccaride esters. Also used in the synthesis of antihyperlipidemic novel compounds involving glycosyl fructose derivatives.<br>References Shen, Y. et al.: Molecules, 17, 8661 (2012); Tiwari, P. et al.: Bioorg. Med. Chem. Lett., 16, 6028 (2006);<br></p>

<p>M03060 - H-Leu-OH</p>

<p>Applications N,N'-Di-4-pyridinyl-methanediamine is used to prepare bis(heteroaryl)-imidazolidinediones with oxalyl chloride.<br>References Ghandi, M., et al.: Synth. Comm., 37, 637 (2007)<br></p>

<p>Stability Hygroscopic<br>Applications 2S,2’S,5S)-5-Hydroxy Lysinonorleucine is one of the stereoisomers of 5-Hydroxylysinonorleucine, reduced collagen cross links.<br>References Astbury, C., et al.: Br. J. Rheumatol., 33, 11 (1994), Watts, N., et al.: Clin. Chem., 45, 1359 (1999), Banse, X., et al.: Bone, 31, 70 (2002),<br></p>

<p>Applications Labeled Sucrose (S697000). Yuanzhen sugar is a polysaccharide polymer, containing a certain amount of fructooligosaccharides.<br>References Watanabe, T., et al.: Biosci. Biotech. Biochem., 72, 3167 (2008), You, Y., et al.: J. Agric. Food Chem., 57, 709 (2009),<br></p>

<p>Stability Hygroscopic<br>Applications 1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester is a possible metabolite of the di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH) monoester (MINCH).<br>References Koch, H., et al.: Arch. Toxicol., 87, 799 (2013)<br></p>

<p>Applications N-Methyl-p-tyramineúHCl (cas# 370-98-9) is a useful research chemical.<br></p>

<p>Applications 3,5-Dihydroxy-4-methoxybenzoic Acid is a useful building block in organic synthesis.<br>References Ghosh, Koushik, et al.: Angewandte Chemie, I.E., 55(27), 7821-7825 (2016);Vergne, Fabrice, et al.: Bioorg. &amp; Medi. Chem. Let., 14(18), 4607-4613 (2004)<br></p>

<p>Stability Hygroscopic<br>Applications A metabolite of 1-methyl-2-thioimidazole (methimazole). It inhibits bone resorption.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Paterson, J.R., et al.: Biochem. Biophys. Res. Comm., 116, 449 (1983), Taurog, A., et al.: Endocrinology, 124, 30 (1989).<br></p>

<p>Applications Fructose-histidine is an amadori compound formed in food.<br>References Wang, J., et al.: J. Mass Spec., 43, 262 (2008); Hashiba, H.: J. Agri. Food Chem., 24, 70 (1976)<br></p>

<p>Impurity Fluorouracil EP Impurity D<br>Applications 5-Methoxyuracil (Fluorouracil EP Impurity D) is methoxylated uracil, a component of nucleid acid. 5-Methoxyuracil is used in the preparation of nucleosides.<br>References Vorbrueggen, H. et al.: Chem. Ber., 114, 1279 (1981); Novacek, A. et al.: Coll. Czech. Chem. Comm., 32, 1045 (1967);<br></p>