Angiogénesis
Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.
Subcategorías de "Angiogénesis"
- BTK(154 productos)
- Bcr-Abl(111 productos)
- EGFR(591 productos)
- FAK(71 productos)
- FLT(87 productos)
- Receptor del factor de crecimiento de fibroblastos (FGFR)(173 productos)
- JAK(245 productos)
- PDGFR(126 productos)
- RAAS(89 productos)
- Src(81 productos)
- Syk(37 productos)
- Trombina(52 productos)
- VDA(2 productos)
- VEGFR(253 productos)
Mostrar 6 subcategorías más
Se han encontrado 1884 productos de "Angiogénesis"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
ONO-4059 analog
CAS:ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.Fórmula:C25H24N6O3Pureza:99.25%Forma y color:SolidPeso molecular:456.5PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Fórmula:C17H17N7Pureza:98.45% - 99.93%Forma y color:SolidPeso molecular:319.36LDN-212854
CAS:LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors.Fórmula:C25H22N6Pureza:98% - 98.71%Forma y color:SolidPeso molecular:406.48SUN11602
CAS:SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.Fórmula:C26H37N5O2Pureza:99.36%Forma y color:SolidPeso molecular:451.6Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Fórmula:C24H27FN6O4Pureza:99.82%Forma y color:SolidPeso molecular:482.51TAK-632
CAS:TAK-632 is a potent pan-Raf inhibitor.Fórmula:C27H18F4N4O3SPureza:98% - 99.5%Forma y color:SolidPeso molecular:554.52R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Fórmula:C16H13FN4O2Pureza:99.27% - 99.84%Forma y color:SolidPeso molecular:312.3CL-387785
CAS:CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.Fórmula:C18H13BrN4OPureza:99.56% - 99.62%Forma y color:SolidPeso molecular:381.23BMS-2
CAS:BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.Fórmula:C25H16F2N4O3Pureza:98.33%Forma y color:SolidPeso molecular:458.42Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Fórmula:C25H21FN6O2SPureza:96.17% - 97.49%Forma y color:SolidPeso molecular:488.54EAI045
CAS:EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Fórmula:C19H14FN3O3SPureza:98.00% - 99.12%Forma y color:SolidPeso molecular:383.4Lorlatinib
CAS:Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogeneFórmula:C21H19FN6O2Pureza:99.77% - 99.95%Forma y color:SolidPeso molecular:406.41GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Fórmula:C21H23N7O2S·HClPureza:99.87%Forma y color:SolidPeso molecular:473.98hVEGF-IN-1
CAS:hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.Fórmula:C34H43N7O2Pureza:99.76% - >99.99%Forma y color:SolidPeso molecular:581.75AD80
CAS:AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.Fórmula:C22H19F4N7OPureza:99.49% - 99.75%Forma y color:SolidPeso molecular:473.43WH-4-023
CAS:WH-4-023 (Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK.Fórmula:C32H36N6O4Pureza:98% - 99.75%Forma y color:SolidPeso molecular:568.67eCF506
CAS:eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)Fórmula:C26H38N8O3Pureza:97.85% - 98.16%Forma y color:SolidPeso molecular:510.63WZ4002
CAS:WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.Fórmula:C25H27ClN6O3Pureza:97.51%Forma y color:SolidPeso molecular:494.97Olafertinib
CAS:Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.Fórmula:C29H28F2N6O2Pureza:98.62% - 99.706%Forma y color:SolidPeso molecular:530.57XL019
CAS:XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.Fórmula:C25H28N6O2Pureza:99.19%Forma y color:SolidPeso molecular:444.53Tofacitinib
CAS:Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.Fórmula:C16H20N6OPureza:99% - >99.99%Forma y color:SolidPeso molecular:312.374-(6,7-dimethoxyquinolin-4-yl)oxyaniline
CAS:4-(6,7-dimethoxyquinolin-4-yl)oxyaniline is a quinoline used in creating drugs and pesticides.Fórmula:C17H16N2O3Pureza:99.93%Forma y color:SolidPeso molecular:296.32Ritlecitinib
CAS:Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity of JAK1/2.Cost-effective and quality-assured.Fórmula:C15H19N5OPureza:98.82% - 99.92%Forma y color:SolidPeso molecular:285.34Agerafenib
CAS:Agerafenib (CEP32496) is a highly potent inhibitor of BRAF.Fórmula:C24H22F3N5O5Pureza:95.78% - 99.23%Forma y color:SolidPeso molecular:517.46PF-6274484
CAS:PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M and WT-EGFR, respectively.Fórmula:C18H14ClFN4O2Pureza:97.71%Forma y color:SolidPeso molecular:372.78Crizotinib
CAS:Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Fórmula:C21H22Cl2FN5OPureza:99% - 99.87%Forma y color:SolidPeso molecular:450.34Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Fórmula:C23H25ClFN7OPureza:99.33% - 99.86%Forma y color:SolidPeso molecular:469.94Ibrutinib
CAS:Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.Fórmula:C25H24N6O2Pureza:98% - 99.93%Forma y color:SolidPeso molecular:440.5AZD8931 diFuMaric acid
CAS:AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).Fórmula:C31H33ClFN5O11Pureza:99.92%Forma y color:SolidPeso molecular:706.1NSC 228155
CAS:NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Fórmula:C11H6N4O4SPureza:99.84%Forma y color:SolidPeso molecular:290.25zanubrutinib
CAS:Zanubrutinib (BGB-3111) is an inhibitor of Bruton tyrosine kinase (BTK).Fórmula:C27H29N5O3Pureza:98.42% - 99.76%Forma y color:SolidPeso molecular:471.55BGG463
CAS:BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with an IC50 of 0.25 μM, 0.09 μM and 0.590 μM, respectively.Fórmula:C30H29F3N6O3Pureza:98.21% - >99.99%Forma y color:SolidPeso molecular:578.58Sapitinib
CAS:Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib orFórmula:C23H25ClFN5O3Pureza:98.89% - 99.83%Forma y color:SolidPeso molecular:473.93ZINC13466751
CAS:<p>ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 µM).</p>Fórmula:C20H21N5O2Pureza:99.8%Forma y color:SolidPeso molecular:363.41Imatinib
CAS:Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFórmula:C29H31N7OPureza:99.42% - 99.94%Forma y color:Off White PowderPeso molecular:493.6BMS-986142
CAS:BMS-986142 is a potent and highly selective reversible BTK inhibitor (IC50: 0.5 nM).Fórmula:C32H30F2N4O4Pureza:99.44% - 99.76%Forma y color:SolidPeso molecular:572.6KI8751
CAS:KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.Fórmula:C24H18F3N3O4Pureza:99.22% - 99.9%Forma y color:SolidPeso molecular:469.41TCS 359
CAS:TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM.Fórmula:C18H20N2O4SPureza:99.31%Forma y color:SolidPeso molecular:360.43Ningetinib Tosylate
CAS:Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Fórmula:C38H37FN4O8SPureza:99.93%Forma y color:SolidPeso molecular:728.79Entospletinib
CAS:Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!Fórmula:C23H21N7OPureza:98.54% - 99.74%Forma y color:SolidPeso molecular:411.46SB 525334
CAS:SB-525334 is a potent and selective inhibitor of the TGF-β1R and ALK5 (IC50: 14.3 nM).Fórmula:C21H21N5Pureza:98.39% - ≥95%Forma y color:SolidPeso molecular:343.42PD168393
CAS:PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Forma y color:SolidPeso molecular:369.22Naquotinib
CAS:Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFRFórmula:C30H42N8O3Pureza:97.49%Forma y color:SolidPeso molecular:562.71Derazantinib
CAS:Derazantinib (ARQ-087) is a potent, ATP-competitive, orally active tyrosine kinase inhibitor.Cost-effective and quality-assured.Fórmula:C29H29FN4OPureza:99.71%Forma y color:SolidPeso molecular:468.57CGI-1746
CAS:CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.Fórmula:C34H37N5O4Pureza:97.69% - 97.88%Forma y color:SolidPeso molecular:579.69KRN-633
CAS:KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.Fórmula:C20H21ClN4O4Pureza:99.53% - 99.73%Forma y color:SolidPeso molecular:416.86Quizartinib
CAS:Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.Fórmula:C29H32N6O4SPureza:98% - 99.42%Forma y color:SolidPeso molecular:560.67Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFórmula:C21H18FN5OPureza:98% - 98.24%Forma y color:SolidPeso molecular:375.4PD-166866
CAS:PD-166866 is a selective FGFR tyrosine kinase inhibitor.Fórmula:C20H24N6O3Pureza:98.29%Forma y color:SolidPeso molecular:396.44Tyrphostin AG 528
CAS:Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).Fórmula:C18H14N2O3Pureza:99.64%Forma y color:SolidPeso molecular:306.32
