Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(127 productos)
- FOXO1(3 productos)
- IAP(65 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(126 productos)
- PDK(9 productos)
- PERK(24 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(91 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5622 productos de "Apoptosis"
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Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Fórmula:C23H22ClNO2Pureza:99.25%Forma y color:Yellowish SolidPeso molecular:379.88NSC 15364
CAS:NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.Fórmula:C13H14N4OPureza:98.67%Forma y color:SolidPeso molecular:242.28Eriocitrin
CAS:<p>Eriocitrin: an antioxidative flavonoid; reduces exercise-induced oxidative damage and lipids; fights fatty liver and inhibits carbonic anhydrase VA.</p>Fórmula:C27H32O15Pureza:98.41% - 99.11%Forma y color:SolidPeso molecular:596.53Mirodenafil dihydrochloride
CAS:<p>Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.</p>Fórmula:C26H39Cl2N5O5SPureza:99.64% - 99.78%Forma y color:SolidPeso molecular:604.59Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Fórmula:C19H23NO4Pureza:99.02% - 99.73%Forma y color:White PowderPeso molecular:329.39Tacedinaline
CAS:<p>Tacedinaline (CI994) is a selective class I HDAC inhibitor with potential antineoplastic activity.</p>Fórmula:C15H15N3O2Pureza:96.83% - 99.15%Forma y color:WhitePeso molecular:269.3W-7 hydrochloride
CAS:<p>W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride</p>Fórmula:C16H22Cl2N2O2SPureza:99.63%Forma y color:White Crystalline SolidPeso molecular:377.32Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Fórmula:C40H52O4Pureza:95.1% - 99.79%Forma y color:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Cysteamine hydrochloride
CAS:<p>Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.</p>Fórmula:C2H7NS·HClPureza:99.34% - 99.87%Forma y color:White Crystalline Powder With A Strong And Disagreeable SmellPeso molecular:113.61SCR130
CAS:<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Fórmula:C19H13Cl2N3O2SPureza:98.9%Forma y color:SolidPeso molecular:418.3Flavokawain A
CAS:NSC-37445 shows anti-tumor properties; Flavokawain A may reduce inflammation by hindering specific signaling in macrophages.Fórmula:C18H18O5Pureza:97.1% - 99.72%Forma y color:SolidPeso molecular:314.332Ganoderic acid D
CAS:<p>Ganoderic acid D, a Ganoderma component, inhibits HeLa cell growth with an IC50 of 17.3µM after 48h.</p>Fórmula:C30H42O7Pureza:98.06% - 99.98%Forma y color:SolidPeso molecular:514.65Pembrolizumab
CAS:<p>Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.</p>Pureza:95% - 99.70%Forma y color:LiquidPeso molecular:149 kDaEGFR-IN-12
CAS:<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Forma y color:SolidPeso molecular:413.4Lupiwighteone
CAS:<p>Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.</p>Fórmula:C20H18O5Pureza:98.92%Forma y color:SolidPeso molecular:338.35NQDI-1
CAS:<p>NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).</p>Fórmula:C19H13NO4Pureza:97.1% - 98.10%Forma y color:SolidPeso molecular:319.31TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Fórmula:C21H17ClN2O6Pureza:97.62% - 99.09%Forma y color:SolidPeso molecular:428.82Solamargine
CAS:Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.Fórmula:C45H73NO15Pureza:99.17% - 99.96%Forma y color:SolidPeso molecular:868.06Angiotensin II human
CAS:<p>Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.</p>Fórmula:C50H71N13O12Pureza:95% - >99.99%Forma y color:SolidPeso molecular:1046.18PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Forma y color:SolidPeso molecular:369.22Mancozeb
CAS:<p>Mancozeb is a fungicide of ethylene-bis-dithiocarbamate.</p>Fórmula:C8H12MnN4S8ZnPureza:98%Forma y color:Grayish-Yellow PowderPeso molecular:541.08Olsalazine
CAS:<p>Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.</p>Fórmula:C14H10N2O6Pureza:99.31%Forma y color:SolidPeso molecular:302.24EF24
CAS:<p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>Fórmula:C19H15F2NOPureza:99.71%Forma y color:SolidPeso molecular:311.33Deferitrin
CAS:<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Fórmula:C11H11NO4SPureza:98.71%Forma y color:SolidPeso molecular:253.27McMMAF
CAS:<p>McMMAF is a protective group-conjugated MMAF.</p>Fórmula:C49H76N6O11Pureza:99.65% - >99.99%Forma y color:SolidPeso molecular:925.16CDPPB
CAS:<p>CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).</p>Fórmula:C23H16N4OPureza:99.16%Forma y color:SolidPeso molecular:364.4CCPA
CAS:<p>CCPA (2-chloro-N(6)cyclopentyladenosine) is a potent and selective agonist of adenosine A1 receptor</p>Fórmula:C15H20ClN5O4Pureza:99.1%Forma y color:Off-White To Light Yellow SolidPeso molecular:369.8Candesartan Cilexetil
CAS:<p>Candesartan Cilexetil, an angiotensin II blocker (IC50: 0.26 nM), turns to candesartan in the body, which dilates blood vessels by hindering AT1.</p>Fórmula:C33H34N6O6Pureza:98.22% - >99.99%Forma y color:White Crystalline PowderPeso molecular:610.66Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Fórmula:C25H32N4O7SPureza:98% - 99.87%Forma y color:SolidPeso molecular:532.61Glafenine Hydrochloride
CAS:<p>Glafenine Hydrochloride is an anti-inflammatory agent.</p>Fórmula:C19H17ClN2O4·HClPureza:98.89%Forma y color:SolidPeso molecular:409.26Pevonedistat
CAS:<p>Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM).</p>Fórmula:C21H25N5O4SPureza:95% - 99.92%Forma y color:SolidPeso molecular:443.52TASIN-1 Hydrochloride
CAS:<p>TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncated</p>Fórmula:C18H29ClN2O3SPureza:99.94%Forma y color:SolidPeso molecular:388.95Paroxetine
CAS:<p>Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.</p>Fórmula:C19H20FNO3Pureza:98.89% - 99.45%Forma y color:White To Off-White PowderPeso molecular:329.37Romidepsin
CAS:Romidepsin (NSC-630176), an IV histone deacetylase inhibitor, treats refractory cutaneous/peripheral T-cell lymphomas.Fórmula:C24H36N4O6S2Pureza:99.4% - 99.94%Forma y color:SolidPeso molecular:540.7TPCK
CAS:<p>TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis</p>Fórmula:C17H18ClNO3SPureza:97.33%Forma y color:PowderPeso molecular:351.85PX-12
CAS:<p>PX-12, a Trx-1 inhibitor, promotes apoptosis, reduces HIF-1α/VEGF, and inhibits tumor growth, suggesting use in advanced cancer therapy.</p>Fórmula:C7H12N2S2Pureza:98% - 99.21%Forma y color:SolidPeso molecular:188.31Fluazinam
CAS:<p>Fluazinam: a pyridinamine fungicide, broad-spectrum, strongly inhibits S. sclerotiorum mycelial growth.</p>Fórmula:C13H4Cl2F6N4O4Pureza:98% - 99.7%Forma y color:Light Yellow CrystalsPeso molecular:465.09PCNA-I1
CAS:<p>PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.</p>Fórmula:C17H14N2O2SPureza:97.64%Forma y color:SolidPeso molecular:310.374-IBP
CAS:4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .Fórmula:C19H21IN2OPureza:98.99%Forma y color:SolidPeso molecular:420.29Lubiprostone
CAS:<p>Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.</p>Fórmula:C20H32F2O5Pureza:97.31% - 98.54%Forma y color:White Odorless Crystals Or Crystalline PowderPeso molecular:390.46RH01687
CAS:<p>RH01687 is a potent β-cell protector , exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress.</p>Fórmula:C12H9ClN6O2SPureza:97.93%Forma y color:SolidPeso molecular:336.76Clodronic acid disodium salt
CAS:<p>Clodronic acid disodium salt (Lodronate), a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.</p>Fórmula:CH4Cl2O6P0·2NaPureza:>99.99% - ≥98%Forma y color:White SolidPeso molecular:288.86Sodium benzoate
CAS:<p>Sodium benzoate (Benzoic acid sodium salt) is a D-Amino Acid Oxidase Inhibitor.Sodium Benzoate is a Food Preservative.</p>Fórmula:C7H5NaO2Pureza:99.72%Forma y color:White Solid CrystallinePeso molecular:144.10HX 531
CAS:<p>HX 531 is a RXR antagonist (IC50 of 18 nM).Cost-effective and quality-assured.</p>Fórmula:C29H29N3O4Pureza:98.59% - 99.86%Forma y color:SolidPeso molecular:483.563-hydroxy-3-phenylpentanamide
CAS:<p>Chiral 3-hydroxy-3-phenylpentanamide: neuroprotective, may treat anxiety/depression/addiction, anticancer.</p>Fórmula:C11H15NO2Pureza:98.42%Forma y color:SolidPeso molecular:193.24Ceftiofur
CAS:<p>Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive/negative, anaerobic and aerobic bacteria encountered by domestic animals.</p>Fórmula:C19H17N5O7S3Pureza:98.26%Forma y color:SolidPeso molecular:523.56Epoxiconazole
CAS:<p>Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation.</p>Fórmula:C17H13ClFN3OPureza:98.57%Forma y color:Solid PowderPeso molecular:329.76PATULIN
CAS:Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.Fórmula:C7H6O4Pureza:99.91% - 99.98%Forma y color:Compact Prisms Or Thick Plates From Ether Or Chloroform White CrystallinePeso molecular:154.12Semaglutide
CAS:Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).Fórmula:C187H291N45O59Pureza:96.92% - 99.78%Forma y color:SolidPeso molecular:41143,4 Dichloroisocoumarin
CAS:<p>3,4 Dichloroisocoumarin is a granzyme, cathepsin G, and neutrolphil elastase inhibitor</p>Fórmula:C9H4Cl2O2Pureza:97.94%Forma y color:SolidPeso molecular:215.03
