Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(127 productos)
- FOXO1(3 productos)
- IAP(65 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(126 productos)
- PDK(9 productos)
- PERK(24 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(91 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5622 productos de "Apoptosis"
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Ro-3306
CAS:<p>RO-3306: ATP-competitive CDK1 inhibitor, Ki 20 nM, >15x more selective than other human kinases.</p>Fórmula:C18H13N3OS2Pureza:97.67% - 99.79%Forma y color:SolidPeso molecular:351.455,7,4'-Trimethoxyflavone
CAS:<p>5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.</p>Fórmula:C18H16O5Pureza:97.53%Forma y color:SolidPeso molecular:312.32Solasodine
CAS:<p>Solasodine, a toxic alkaloid from Solanaceae, kills HeLa cervical cancer and U937 leukemia cells.</p>Fórmula:C27H43NO2Pureza:99.64% - 99.94%Forma y color:SolidPeso molecular:413.64Tauroursodeoxycholate
CAS:<p>Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.</p>Fórmula:C26H45NO6SPureza:98.77% - 99.93%Forma y color:White SolidPeso molecular:499.7PTC-028
CAS:<p>PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected.</p>Fórmula:C19H12F5N5Pureza:97.61% - 98.12%Forma y color:SolidPeso molecular:405.32PEAQX
CAS:<p>PEAQX (NVP-AAM077) is an oral NMDA antagonist, inhibits 1A/2A receptors (IC50: 270 nM), less so 1A/2B (IC50: 29,600 nM).</p>Fórmula:C17H17BrN3O5PPureza:98% - 99.9%Forma y color:SolidPeso molecular:454.21Divalproex Sodium
CAS:Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted byFórmula:C8H16O2·C8H15O2·NaPureza:99.87%Forma y color:A White Powder With A Characteristic OdorPeso molecular:310.41Bilobalide
CAS:<p>Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.</p>Fórmula:C15H18O8Pureza:98.81% - 99.92%Forma y color:White SolidPeso molecular:326.3Tamibarotene
CAS:Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplasticFórmula:C22H25NO3Pureza:98.55% - 99.73%Forma y color:Crystalline SolidPeso molecular:351.44PCI-34051
CAS:<p>PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).</p>Fórmula:C17H16N2O3Pureza:97.219% - 98.29%Forma y color:SolidPeso molecular:296.32Ipatasertib
CAS:<p>Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.</p>Fórmula:C24H32ClN5O2Pureza:98.28% - 99.21%Forma y color:SolidPeso molecular:458Sulforaphane
CAS:<p>Sulforaphane is a natural isothiocyanate that activates Nrf2. Sulforaphane has antitumor and anti-inflammatory activities. Cost-effective and quality-assured.</p>Fórmula:C6H11NOS2Pureza:95% - 99.79%Forma y color:Light Yellow LiquidPeso molecular:177.29ZZW-115 hydrochloride
CAS:ZZW-115 hydrochloride inhibits the activity of NUPR1.Fórmula:C24H34Cl3F3N4SPureza:99.97%Forma y color:SolidPeso molecular:573.97Chromium picolinate
CAS:<p>Chromium picolinate causes DNA damage and mutation. It is an activator of p38.</p>Fórmula:C18H12CrN3O6Pureza:99.64%Forma y color:Violet-Red Crystalline PowderPeso molecular:418.30MI-136
CAS:<p>MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.</p>Fórmula:C23H21F3N6SPureza:98.63% - 99.12%Forma y color:SolidPeso molecular:470.51OSI-930
CAS:<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Fórmula:C22H16F3N3O2SPureza:99.67%Forma y color:SolidPeso molecular:443.44AGK2
CAS:<p>AGK2（IC50=3.5 μM） is an effective, and specific SIRT2 inhibitor.</p>Fórmula:C23H13Cl2N3O2Pureza:98.68% - 99.17%Forma y color:SolidPeso molecular:434.27Thalidomide-NH-PEG1-NH2 hydrochloride
CAS:<p>Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-</p>Fórmula:C17H21ClN4O5Pureza:97.13%Forma y color:SolidPeso molecular:396.83Tetrahydroxyquinone monohydrate
CAS:<p>Anticataract compound; redox-active; forms ROS via semiquinone radical cycle.</p>Fórmula:C6H6O7Forma y color:SolidPeso molecular:190.11Apocynin
CAS:<p>Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).</p>Fórmula:C9H10O3Pureza:99.71% - 99.98%Forma y color:Yellowish To Brown PowderPeso molecular:166.17RHPS4
CAS:<p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>Fórmula:C22H17F2N2·CH3O4SPureza:99.72%Forma y color:SolidPeso molecular:458.48Leachianone A
CAS:<p>Leachianone A (Isokurarinone) is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity.</p>Fórmula:C26H30O6Pureza:98.53% - 99.79%Forma y color:SolidPeso molecular:438.51SP-141
CAS:<p>SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.</p>Fórmula:C22H16N2OPureza:98.01%Forma y color:SolidPeso molecular:324.38Alda-1
CAS:<p>Alda-1 activates ALDH2*1 and ALDH2*2, permeates cells, and targets mitochondrial aldehyde dehydrogenase 2.</p>Fórmula:C15H11Cl2NO3Pureza:98.5% - 99.63%Forma y color:SolidPeso molecular:324.16Metamizole magnesium
CAS:<p>Metamizole magnesium (Metamizolemagnesiumsalt) is a pain reliever, which can antispasmodic.</p>Fórmula:C26H32MgN6O8S2Pureza:93.51%Forma y color:SolidPeso molecular:645.01ARRY 520 hydrochloride
CAS:<p>'ARRY 520 hydrochloride: a KSP inhibitor causing apoptosis and strong anti-proliferative effects.'</p>Fórmula:C20H23ClF2N4O2SPureza:98.06% - 99.62%Forma y color:SolidPeso molecular:456.94PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Fórmula:C15H11NSPureza:98.00%Forma y color:SolidPeso molecular:237.32Eltrombopag Olamine
CAS:<p>Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin</p>Fórmula:C29H36N6O6Pureza:99.59% - 99.89%Forma y color:SolidPeso molecular:564.63L-Glutamic acid monosodium salt
CAS:<p>L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.</p>Fórmula:C5H8NO4·NaPureza:99.93%Forma y color:White Solid CrystallinePeso molecular:169.11HA15
CAS:<p>HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.</p>Fórmula:C23H22N4O3S2Pureza:99.77% - 99.86%Forma y color:SolidPeso molecular:466.58Kevetrin hydrochloride
CAS:<p>Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potential</p>Fórmula:C5H10ClN3SPureza:99.32% - 99.93%Forma y color:SolidPeso molecular:179.67Scoulerine
CAS:<p>Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).</p>Fórmula:C19H21NO4Pureza:98.62%Forma y color:SolidPeso molecular:327.37Thalidomide 4-fluoride
CAS:<p>Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand.</p>Fórmula:C13H9FN2O4Pureza:99.12%Forma y color:SolidPeso molecular:276.22CA-4948
CAS:<p>CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.</p>Fórmula:C24H25N7O5Pureza:99.35% - 99.88%Forma y color:SolidPeso molecular:491.5Tenovin-6
CAS:<p>Tenovin-6 is a p53 transcriptional activity agonist.</p>Fórmula:C25H34N4O2SPureza:97.71% - >99.99%Forma y color:SolidPeso molecular:454.633-O-Acetyloleanolic acid
CAS:<p>3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells.</p>Fórmula:C32H50O4Pureza:98% - 99.57%Forma y color:SolidPeso molecular:498.74Berbamine dihydrochloride
CAS:<p>Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.</p>Fórmula:C37H42Cl2N2O6Pureza:95% - 99.99%Forma y color:SolidPeso molecular:681.65PS210
CAS:<p>PS210 selectively activates PDK1 (Kd: 3 μM), doesn't affect PDK1 downstream kinases. Prodrug PS423 inhibits PDK1-mediated S6K phosphorylation.</p>Fórmula:C19H15F3O5Pureza:99.78%Forma y color:SolidPeso molecular:380.31Alofanib
CAS:<p>Alofanib (RPT835) selectively inhibits FGFR2 in KATO III cells with IC50 <10 nM; doesn’t affect FGFR1/3 or FGF2-FGFR2 binding.</p>Fórmula:C19H15N3O6SPureza:99.53% - 99.81%Forma y color:SolidPeso molecular:413.4Cucurbitacin IIA
CAS:<p>1.</p>Fórmula:C32H50O8Pureza:98.62% - 99.87%Forma y color:SolidPeso molecular:562.73Curcumol
CAS:<p>Curcumol ((-)-Curcumol), a pure monomer isolated extracted from Rhizoma Curcumaeis, has antitumor activities.</p>Fórmula:C15H24O2Pureza:98.99% - 99.87%Forma y color:SolidPeso molecular:236.35ONO-4059 analog
CAS:<p>ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.</p>Fórmula:C25H24N6O3Pureza:99.25%Forma y color:SolidPeso molecular:456.5N-Ethylmaleimide
CAS:<p>N-Ethylmaleimide (NEM) is a reagent for alkylation of free sulfhydryl groups, a cysteine protease inhibitor. Cost-effective and quality-assured.</p>Fórmula:C6H7NO2Pureza:99.50%Forma y color:White SolidPeso molecular:125.13Thalidomide-O-COOH
CAS:<p>Thalidomide-O-COOH is a Cereblon ligand for CRBN protein recruitment and PROTAC construction with a linker.</p>Fórmula:C15H12N2O7Pureza:98% - 98.29%Forma y color:SolidPeso molecular:332.27Galgravin
CAS:<p>Galgravin combats inflammation, safeguards neurons, promotes neurite growth, and resists Abeta25-35 and MPP+ toxicity.</p>Fórmula:C22H28O5Pureza:99.75% - 99.88%Forma y color:SolidPeso molecular:372.45SC-43
CAS:<p>SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).</p>Fórmula:C21H13ClF3N3O2Pureza:98.44%Forma y color:SolidPeso molecular:431.8Sanguinarine
CAS:<p>Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.</p>Fórmula:C20H14NO4Pureza:99.04% - 99.76%Forma y color:SolidPeso molecular:332.33Clovamide
CAS:<p>Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T.</p>Fórmula:C18H17NO7Pureza:97.12% - 97.68%Forma y color:SolidPeso molecular:359.33Salermide
CAS:<p>Salermide is an inhibitor of Sirt1 and Sirt2, causing strong cancer-specific apoptotic cell death.</p>Fórmula:C26H22N2O2Pureza:97.09% - 99.55%Forma y color:SolidPeso molecular:394.47CVT-11127
CAS:<p>CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.</p>Fórmula:C25H23Cl2N5O3Pureza:98.32%Forma y color:SolidPeso molecular:512.39
