Endocrinología / Hormonas
Los inhibidores de endocrinología/hormonas son compuestos que bloquean la acción de las hormonas o interfieren con las vías de señalización hormonal. Estos inhibidores son esenciales para estudiar la regulación de los sistemas endocrinos y para desarrollar tratamientos para enfermedades relacionadas con las hormonas, como la diabetes, los trastornos tiroideos y los cánceres dependientes de hormonas. Al modular la actividad hormonal, estos inhibidores pueden ayudar a dilucidar las complejas interacciones dentro del sistema endocrino. En CymitQuimica, ofrecemos una amplia gama de inhibidores de endocrinología/hormonas de alta calidad para apoyar su investigación en endocrinología, farmacología y ciencias médicas.
Subcategorías de "Endocrinología / Hormonas"
- Receptor de andrógenos(229 productos)
- Anexina A(16 productos)
- Aromatasa(23 productos)
- Receptor de estrógeno / progestágeno(66 productos)
- GPR(1 productos)
- Receptor de glucocorticoides(165 productos)
- LHRH(2 productos)
- Receptor de opioides(327 productos)
- Receptor de prostaglandinas(122 productos)
- RAAS(89 productos)
- Reductasa(51 productos)
- Somatostatina(57 productos)
- Receptor de la hormona tiroidea (THR)(33 productos)
- Receptor de vasopresina(48 productos)
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Se han encontrado 3420 productos de "Endocrinología / Hormonas"
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AKR1Cs-IN-1
AKR1Cs-IN-1 (Compound 29) is an effective and broad-spectrum inhibitor of the Aldo-Keto Reductase 1C family (AKR1C1-1C4). It achieves subtype inhibition by simultaneously binding to the SP2 and SP3 pockets, thereby blocking metabolic pathways related to drug resistance. In enzyme assays, AKR1Cs-IN-1 exhibits significant inhibitory activity with IC50 values of 0.09, 0.28, 0.05, and 0.51 µM for AKR1C1, AKR1C2, AKR1C3, and AKR1C4, respectively. The compound shows excellent resensitizing effects in doxorubicin (DOX)-resistant breast cancer cell line MCF-7/ADR, effectively enhancing the cytotoxicity of DOX. AKR1Cs-IN-1 holds promise for research on breast cancer resistance.Forma y color:Odour Solid[Orn8]-Urotensin II
CAS:[Orn8]-Urotensin II is a Urotensin receptor ligand and a partial agonist at Urotensin receptors.Fórmula:C63H83N13O18S2Forma y color:SolidPeso molecular:1374.5517-Epiestriol
CAS:17-Epiestriol, metabolite of estrone, forms via 16α-hydroxy intermediate and binds ERα and ERβ with affinity less than 17β-estradiol.Fórmula:C18H24O3Pureza:99.72%Forma y color:SolidPeso molecular:288.38Emd 55068
CAS:Emd 55068 is a synthetic antagonist of renin.Fórmula:C41H65N9O6Forma y color:SolidPeso molecular:780.01(S)-CVN424
CAS:(S)-CVN424 modulates GPR6, key for neurological/psychiatric research, including Parkinson's.Fórmula:C24H29F2N5O3Forma y color:SolidPeso molecular:473.525Nocistatin
CAS:Nocistatin, a neuropeptide, blocks Nociceptin effects and inhibits 5-HT release, acting on an opioid-related receptor.Fórmula:C32H56N10O12Forma y color:SolidPeso molecular:772.85Helianorphin-19
Helianorphin-19: Potent KOR agonist (Ki=25 nM; EC50=45 nM), 200x selective over μ/δ receptors, effective in mouse pain model, non-sedative.Forma y color:LiquidTRV056
CAS:TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.Fórmula:C52H74N14O13Forma y color:SolidPeso molecular:1103.249β-Lipotropin (60-65)
CAS:β-Lipotropin (60-65) (β-LPH (60-65)), an opioid agonist, is a significant [1] opioid peptide.Fórmula:C33H47N9O8SForma y color:SolidPeso molecular:729.85DP32
CAS:DP32 is a dual-function compound incorporating an opioid receptor (MOP) agonist and a neuropeptide FF receptor (NPFFR) antagonist. It is applicable in analgesia-related research.Fórmula:C57H77N13O7Forma y color:SolidPeso molecular:1056.30[DAla2, DArg6] Dynorphin A, (1-13) (porcine)
CAS:'[DAla2, DArg6] Dynorphin A (1-13) porcine is a potent opioid peptide resistant to enzymatic degradation.'Fórmula:C76H128N24O15Forma y color:SolidPeso molecular:1617.98β-Endorphin (rat)
CAS:β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities.Fórmula:C157H254N42O44SForma y color:SolidPeso molecular:3466.07Dynorphin B (1-13) (TFA)
Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor .Fórmula:C76H116N21F3O19Forma y color:SolidPeso molecular:1684.86Kylo-0603
CAS:KYLO-0603 is an orally active and selective THR-β agonist with an EC50 of 31.07 nM. It effectively reduces serum cholesterol and low-density lipoprotein cholesterol levels. By activating THR-β receptors, KYLO-0603 enhances the expression of THR-regulated genes like iodothyronine deiodinase 1 (Dio1), malic enzyme 1 (Me1), and thyroid hormone-responsive (Thrsp) gene, while it inhibits the expression of inflammatory and fibrosis-related genes, including low-density lipoprotein receptor (LDL-R) gene. This compound is applicable for the study of metabolic associated steatohepatitis (MASH) and liver fibrosis.Fórmula:C81H134N8O28Forma y color:SolidPeso molecular:1667.97(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8)
CAS:E-2078, known chemically as (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8), is a stable analog of Dynorphin A (1–8) and functions as a kappa opioidFórmula:C50H81N15O9Forma y color:SolidPeso molecular:1036.27PRL 3195
CAS:PRL 3195: Somatostatin antagonist, Ki: 6 nM (sst5), 17 nM (sst2), 66 nM (sst3), 1 μM (sst1/4).Fórmula:C58H69ClN12O9S2Forma y color:SolidPeso molecular:1177.83ALR2-IN-6
ALR2-IN-6 (compound 9) is a potent competitive inhibitor of ALR2, with a Ki value of 0.064 μM. It is applicable in research related to neuropathy, retinopathy, and nephropathy.Fórmula:C21H19BrFN3OForma y color:SolidPeso molecular:427.06955Prepro-TRH-(160-169)
CAS:Prepro-TRH-(160-169), a pro-TRH peptide, enhances TRH-stimulated TSH secretion.Fórmula:C54H75N11O18SForma y color:SolidPeso molecular:1198.3THR-β agonist 2 diacetate
THR-β agonist 2 diacetate (Compound 3) is a potent THR-β agonist with potential applications in researching metabolic disorders such as obesity, hyperlipidemia, hypercholesterolemia, and diabetes, as well as other conditions like steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis, and other related diseases and conditions.Forma y color:Odour SolidAc-RYYRWK-NH2 TFA
CAS:Ac-RYYRWK-NH2: potent, specific NOP receptor partial agonist with 0.071 nM affinity; no affinity for μ/κ/δ-opioid receptors.Fórmula:C51H70F3N15O11Forma y color:SolidPeso molecular:1126.21
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