Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(98 productos)
- Receptor de adiponectina(5 productos)
- CFTR(66 productos)
- Receptor CGRP(54 productos)
- Canal de calcio(528 productos)
- Canal de cloruro(52 productos)
- Receptor GABA(360 productos)
- Transportador de monoamina(28 productos)
- Transportador de monocarboxilato(18 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(9 productos)
- OAT(31 productos)
- OCT(7 productos)
- P-gp(54 productos)
- Canal de potasio(280 productos)
- Bomba de protones(42 productos)
- SGLT(31 productos)
- Canal de sodio(206 productos)
- Canal TRP / TRPV(94 productos)
Mostrar 13 subcategorías más
Se han encontrado 2460 productos de "Transportador de membrana / canal de iones"
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JNJ-17203212
CAS:JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).Fórmula:C17H15F6N5OPureza:99.18%Forma y color:SolidPeso molecular:419.32TCN 201
CAS:TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit.Fórmula:C21H17ClFN3O4SPureza:98.5%Forma y color:SolidPeso molecular:461.89Felbamate
CAS:Felbamate (W-554) is an Anti-epileptic Agent.Fórmula:C11H14N2O4Pureza:99% - >99.99%Forma y color:White Powder SolidPeso molecular:238.24Amifampridine phosphate
CAS:Amifampridine treats rare muscle diseases like LEMS and congenital myasthenias, targeting specific enzyme defects.Fórmula:C5H10N3O4PForma y color:SolidPeso molecular:207.12GMQ hydrochloride
CAS:<p>GMQ hydrochloride, a potent ASIC modulator, activates ASIC3 at neutral pH and inhibits acid-induced peak current.</p>Fórmula:C10H12ClN5Pureza:99.64%Forma y color:SolidPeso molecular:237.69AUT1
CAS:AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).Fórmula:C18H19N3O4Pureza:99.8% - 99.95%Forma y color:SolidPeso molecular:341.36Nicainoprol
CAS:<p>Nicainoprol (RU-42924) is a fast-sodium-channel blocking drug. Nicainoprol is a potent antiarrhythmic agent.</p>Fórmula:C21H27N3O3Pureza:99.54%Forma y color:SolidPeso molecular:369.46Levcromakalim
CAS:Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.Fórmula:C16H18N2O3Pureza:99.74%Forma y color:SolidPeso molecular:286.33Gabazine free base
CAS:Gabazine free base is a specific antagonist of the GABA receptor. It does not affect GABA-transaminase or glutamate-decarboxylase activities.Fórmula:C15H17N3O3Forma y color:SolidPeso molecular:287.31(E)-3,4,5-Trimethoxycinnamic acid
CAS:<p>(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.</p>Fórmula:C12H14O5Pureza:99.83%Forma y color:SolidPeso molecular:238.24Methyl homoveratrate
CAS:Methyl homoveratrate, a McN5691 (RWJ-26240) metabolite detected in vivo in plasma, urine, and fecal extracts, functions as a voltage-sensitive calcium channelFórmula:C11H14O4Pureza:99.48%Forma y color:SolidPeso molecular:210.23Piperazine citrate
CAS:<p>Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring.</p>Fórmula:C24H46N6O14Pureza:99.8%Forma y color:Crystals IndicationPeso molecular:642.65O4I1
CAS:<p>O4I1 is an effective Oct3/4 inducer.</p>Fórmula:C16H15NO2Pureza:96.25% - 99.47%Forma y color:SolidPeso molecular:253.39-Phenanthrol
CAS:<p>9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.</p>Fórmula:C14H10OPureza:98.48%Forma y color:SolidPeso molecular:194.23Glibenclamide potassium
CAS:<p>Glibenclamide potassium, a more soluble form of Glibenclamide, exists as anhydrous and hydrate salts.</p>Fórmula:C23H27ClKN3O5SForma y color:SolidPeso molecular:532.09Neramexane HCl
CAS:PAC is a cyclic amine used as a chiral auxiliary in various asymmetric syntheses.Fórmula:C11H24ClNPureza:95.00%Forma y color:SolidPeso molecular:205.768Tricaine methanesulfonate
CAS:<p>Tricaine methanesulfonate (TMS/MS-222) is an anesthetic used in hatcheries and studies to immobilize fish for marking, transport, and invasive procedures.</p>Fórmula:C10H15NO5SPureza:99.259% - 99.86%Forma y color:White PowderPeso molecular:261.30TRPM4-IN-1
CAS:TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.Fórmula:C15H11Cl2NO4Pureza:97.22%Forma y color:SolidPeso molecular:340.16Caroverine hydrochloride
CAS:Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.Fórmula:C22H28ClN3O2Pureza:98.37% - 98.75%Forma y color:SolidPeso molecular:401.9SSD114 HCl
CAS:<p>SSD114 is a novel GABAB receptor positive allosteric modulator.</p>Fórmula:C18H21ClF3N3OPureza:99.03% - 99.95%Forma y color:SolidPeso molecular:387.83Icenticaftor
CAS:Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.Fórmula:C12H13F6N3O3Pureza:99.76%Forma y color:SolidPeso molecular:361.24VU0071063
CAS:VU0071063 is a Kir6.2/SUR1 activator.Fórmula:C18H22N4O2Pureza:99.33%Forma y color:SolidPeso molecular:326.39BzATP triethylammonium salt
CAS:BzATP triethylammonium salt is a P2X7 receptor agonist.Fórmula:C30H39N6O15P3Pureza:95% - 99.57%Forma y color:SolidPeso molecular:816.59Temgicoluril
CAS:<p>Temgicoluril (mebikar) acts on GABA Receptor.</p>Fórmula:C8H14N4O2Pureza:99.8%Forma y color:SolidPeso molecular:198.22MK6-83
CAS:MK6-83 is the transient receptor potential channel ML3 agonist.Fórmula:C16H20N2O2S2Pureza:99.5%Forma y color:SolidPeso molecular:336.47Pico145
CAS:<p>Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.</p>Fórmula:C23H20ClF3N4O5Pureza:99.06%Forma y color:SolidPeso molecular:524.88Tariquidar dihydrochloride
CAS:Tariquidar dihydrochloride, also known as XR9576 dihydrochloride, is a potent, specific P-glycoprotein (P-gp) inhibitor exhibiting high affinity (Kd = 5.1 nM).Fórmula:C38H40Cl2N4O6Forma y color:SolidPeso molecular:719.65GSK369796 Dihydrochloride
CAS:GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.Fórmula:C20H24Cl3N3OPureza:>99.99%Forma y color:SolidPeso molecular:428.78GSK2193874
CAS:GSK2193874 was identified as a selective, orally active TRPV4 blocker.Fórmula:C37H38BrF3N4OPureza:99.99% - ≥95%Forma y color:SolidPeso molecular:691.62Dofetilide
CAS:Dofetilide (UK 68789), a class III antiarrhythmic sulfonamide, blocks Ikr cardiac channels, prolongs action potential, and treats atrial fibrillation/flutter.Fórmula:C19H27N3O5S2Pureza:97.85% - 99.06%Forma y color:Off-White Or Yellowish Crystalline PowderPeso molecular:441.56Chembridge-5861528
CAS:Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM.Fórmula:C19H23N5O3Pureza:99.97%Forma y color:SolidPeso molecular:369.42AZD7507
CAS:AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.Fórmula:C23H27FN6O3Pureza:99.55% - 99.78%Forma y color:SolidPeso molecular:454.5RN-1747
CAS:<p>RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist (IC50: 4 μM).</p>Fórmula:C17H18ClN3O4SPureza:99.29%Forma y color:SolidPeso molecular:395.86HC067047 Hydrochloride(883031-03-6 free base)
CAS:HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 nM, 133 nM, and 17 nM.Fórmula:C26H29ClF3N3O2Pureza:99.95%Forma y color:SolidPeso molecular:507.98DL-Willardiine
CAS:DL-Willardiine (2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid) is an unnatural amino acid, a derivative of glutamate.Fórmula:C7H9N3O4Pureza:99.83%Forma y color:SolidPeso molecular:199.16ICA-105574
CAS:ICA-105574 activates hERG, enhancing peak current and shortening action potential, while modulating activation kinetics.Fórmula:C19H14N2O4Pureza:98.89%Forma y color:SolidPeso molecular:334.33A2793
CAS:<p>A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.</p>Fórmula:C13H12ClNO3Pureza:98.54%Forma y color:SolidPeso molecular:265.69Dotinurad
CAS:Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).Fórmula:C14H9Cl2NO4SPureza:97.43% - 98.04%Forma y color:SolidPeso molecular:358.2Vanillyl butyl ether
CAS:Vanillyl butyl ether (Butyl vanillyl ether) (VBE)is a capsaicin analogue,induce sensory irritation in humans,Vanillyl butyl ether is an alkoxy-substitutedFórmula:C12H18O3Pureza:99.57%Forma y color:Yellowish Liquid LiquidPeso molecular:210.27Tiagabine hydrochloride hydrate
CAS:<p>Tiagabine HCl hydrate, IC50: 67-446 nM, selectively inhibits GABA uptake, acts as an anticonvulsant.</p>Fórmula:C20H28ClNO3S2Forma y color:SolidPeso molecular:430.02BTS
CAS:BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .Fórmula:C14H15NO2SPureza:99.45%Forma y color:White Crystalline SolidPeso molecular:261.34S107
CAS:<p>S107 stabilizes RyR2 by improving calstabin2 binding to mutant/PKA-phosphorylated channels.</p>Fórmula:C11H15NOSPureza:99.90%Forma y color:SolidPeso molecular:209.31AM92016
CAS:AM92016 is a specific blocker of the time dependent delayed rectifier potassium current. AM92016 does not show any β-adrenoceptor blocking activity.Fórmula:C26H30Cl2N2O6SForma y color:SolidPeso molecular:569.49Quadrol
CAS:<p>Quadrol (EDTP) is an immunostimulant, accelerated wound healing.</p>Fórmula:C14H32N2O4Pureza:99.91% - 99.92%Forma y color:Viscous Liquid Liquid ViscousPeso molecular:292.41Parimifasor
CAS:Parimifasor (LYC30937) is an immunomodulator, with anti-inflammatory activity.Fórmula:C18H11Cl2F4N5OPureza:96.77% - 98.97%Forma y color:SolidPeso molecular:460.21YHO-13351
CAS:YHO-13351 is an ABCG2 inhibitor that induces sensitization of cancer stem cells/initiating-like side population cells to irinotecan.Fórmula:C27H37N3O7S2Pureza:97.88%Forma y color:SolidPeso molecular:579.73Cis-ACBD
CAS:Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) is a potent and selective N-methyl-D-aspartate receptor agonist.Fórmula:C6H9NO4Pureza:99.77%Forma y color:SolidPeso molecular:159.14rac-BHFF
CAS:<p>rac-BHFF, a GABA B receptor modulator, boosts GABA potency >15x, efficacy >149%, has anxiolytic effects, and is orally active.</p>Fórmula:C17H21F3O3Pureza:99.69% - >99.99%Forma y color:SolidPeso molecular:330.34Guan-fu base A hydrochloride(1394-48-5 free base)
CAS:<p>Guanfu base A HCl, an antiarrhythmic from Aconitum coreanum, inhibits CYP2D6 in humans, monkeys, and dogs.</p>Fórmula:C24H32NO6ClPureza:99.9%Forma y color:SolidPeso molecular:465.97VU590 HCl
CAS:VU590 is a small molecule inhibitor of KCNJ1 (IC50 = 294 nM).Fórmula:C24H34Cl2N4O7Forma y color:SolidPeso molecular:561.457
