Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(98 productos)
- Receptor de adiponectina(5 productos)
- CFTR(66 productos)
- Receptor CGRP(53 productos)
- Canal de calcio(525 productos)
- Canal de cloruro(51 productos)
- Receptor GABA(355 productos)
- Transportador de monoamina(26 productos)
- Transportador de monocarboxilato(18 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(9 productos)
- OAT(28 productos)
- OCT(7 productos)
- P-gp(52 productos)
- Canal de potasio(280 productos)
- Bomba de protones(40 productos)
- SGLT(31 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(94 productos)
Mostrar 13 subcategorías más
Se han encontrado 2430 productos de "Transportador de membrana / canal de iones"
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ML252
CAS:ML252 selectively inhibits KCNQ2 (IC50=69nM) and Cytochrome P450 isoforms CYP1A2, CYP2C9, CYP3A4, CYP2D6 with low nanomolar IC50s.Fórmula:C20H24N2OForma y color:SolidPeso molecular:308.42XPC-6444
CAS:XPC-6444 is a isoform-selective, and CNS-penetrant inhibitor of NaV1.6 with IC50 of41 nM for hNaV1.6,with anticonvulsant activity.Fórmula:C22H25F3N4O2S2Pureza:98%Forma y color:SolidPeso molecular:498.58(BrMT)2
CAS:(BrMT)2 is an activator of the Kv1.1 potassium ion channel.Fórmula:C20H20Br2N4S2Forma y color:SolidPeso molecular:540.34RPR-260243
CAS:RPR-260243 is a novel activator of HERG and modifies HERG currents inhibited by dofetilide (IC50 = 58 nM).Fórmula:C28H25F3N2O4Pureza:98%Forma y color:SolidPeso molecular:510.5β-CCB
CAS:benzodiazepine receptor ligandFórmula:C16H16N2O2Pureza:98%Forma y color:SolidPeso molecular:268.31UCL-1848 trifluoroacetate salt
CAS:<p>UCL-1848 trifluoroacetate salt is a selective Ca2+-activated, SK potassium channel blocker.</p>Fórmula:C32H34F6N4O4Pureza:98%Forma y color:SolidPeso molecular:652.638UBP714
CAS:UBP714, derived from UBP608, boosts NMDAR in CA1 hippocampus, promising for schizophrenia and cognitive deficits treatment.Fórmula:C11H7BrO4Pureza:98%Forma y color:SolidPeso molecular:283.07ZD-9379
CAS:ZD-9379 is a NMDA receptor antagonist.Fórmula:C19H14ClN3O4Pureza:98%Forma y color:SolidPeso molecular:383.79Ro 8-4304 hydrochloride
CAS:Ro 8-4304 hydrochloride is a NMDA receptor antagonist.Fórmula:C21H24ClFN2O3Pureza:98%Forma y color:SolidPeso molecular:406.88YM 244769 hydrochloride
CAS:inhibitor of the reverse mode of Na+/Ca2+ exchange (NCX)Fórmula:C26H23ClFN3O3Pureza:98%Forma y color:SolidPeso molecular:479.93WX-081
CAS:WX-081 is an anti-TB drug effective against DS-TB (MIC: 0.083 μg/ml) and MDR-TB strains (MIC: 0.11 μg/ml) with hERG inhibition (IC50: 1.89 μM).Fórmula:C34H33ClN2O2Forma y color:SolidPeso molecular:537.09RH 3421
CAS:RH 3421 is used as a neuroactive dihydropyrazole insecticide.Fórmula:C20H17ClF3N3O3Pureza:98%Forma y color:SolidPeso molecular:439.82Ro 25-6981 HCl
CAS:Ro 25-6981 HCl is an effective and selective NMDA glutamate receptors containing the NR2B subunit antagonist.Fórmula:C22H30ClNO2Pureza:98%Forma y color:SolidPeso molecular:375.93Biricodar dicitrate
CAS:Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be used to study prostate cancer.Fórmula:C46H57N3O21Pureza:97.78% - 99.78%Forma y color:SolidPeso molecular:987.95Sabiporide
CAS:Sabiporide is a NHE-1 inhibitor and a cardioprotective agent.Fórmula:C18H20ClF3N6O2Forma y color:SolidPeso molecular:444.84LY339434
CAS:LY339434 is a potent and selective agonist of the kainate receptor GluK1, GluR5.Fórmula:C18H19NO4Pureza:98%Forma y color:SolidPeso molecular:313.35Abeprazan
CAS:<p>Abeprazan is a potassium-competitive acid blocker targeting acid-related diseases without acid activation.</p>Fórmula:C19H17F3N2O3SPureza:98%Forma y color:SolidPeso molecular:410.41Homoquinolinic acid
CAS:NMDA receptor agonistFórmula:C8H7NO4Pureza:98%Forma y color:SolidPeso molecular:181.15CCD-3693
CAS:CCD-3693 is a gamma-aminobutyric acid (GABA) receptor agonist.Fórmula:C21H31F3O2Pureza:98%Forma y color:SolidPeso molecular:372.46GABA-AT-IN-1
CAS:GABA-AT-IN-1 (Compound 6) is an inhibitor of γ-aminobutyric acid transaminase (GABA-AT) that crosses the blood-brain barrier.Fórmula:C23H18N2O6Forma y color:SolidPeso molecular:418.4KRN4884
CAS:KRN 4884 activates KATP channels (EC50=0.55 μM) at 0.1-3 μM with 1 mM ATP.Fórmula:C15H14ClN5Pureza:98%Forma y color:SolidPeso molecular:299.76Farnesyl pyrophosphate
CAS:Farnesyl pyrophosphate: 15-C isoprenoid, TRPM2 agonist, crucial for cholesterol, ubiquinones, protein farnesylation, and GGPP synthesis.Fórmula:C15H28O7P2Forma y color:SolidPeso molecular:382.33Picoprazole
CAS:Picoprazole is a specific H+/K+-ATPase inhibitor (IC50 of 3.1±0.4 μM).Fórmula:C17H17N3O3SPureza:98%Forma y color:SolidPeso molecular:343.4Nav1.8-IN-2
CAS:Nav1.8-IN-2 (compound 35A) strongly inhibits Nav1.8 (IC50: 0.4 nM), useful for researching pain, cough, and pruritus.Fórmula:C18H13Cl2F3N2O3Forma y color:SolidPeso molecular:433.21FR-168888 mesylate
CAS:FR-168888, a new Na+/H+ exchange inhibitor, can protect the heart from arrhythmia and myocardial cell death in ischemic and reperfused situations.Fórmula:C14H18N4O5SPureza:98%Forma y color:SolidPeso molecular:354.38Istaroxime oxalate
CAS:<p>Istaroxime (PST-2744) is a positive inotrope that inhibits Na+/K+ ATPase, raising intracellular sodium and calcium levels.</p>Fórmula:C23H34N2O7Forma y color:SolidPeso molecular:450.53Terodiline hydrochloride
CAS:<p>Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),</p>Fórmula:C20H28ClNPureza:98%Forma y color:SolidPeso molecular:317.9Nav1.7-IN-6
CAS:Nav1.7-IN-6, a selective inhibitor of Nav1.7.Fórmula:C25H25ClF6N2O4SPureza:98%Forma y color:SolidPeso molecular:598.99PKF050-638
CAS:<p>PKF050-638 disrupts CRM1-NES, inhibits HIV-1 Rev export; selective with IC50=0.04 μM.</p>Fórmula:C13H13ClN4O2Pureza:98%Forma y color:SolidPeso molecular:292.72Lemildipine
CAS:Lemildipine is a new blocker of dihydropyridine calcium entry.Fórmula:C20H22Cl2N2O6Forma y color:SolidPeso molecular:457.3CGP 36216 hydrochloride
CAS:CGP 36216 hydrochloride is a potent and selective antagonist of GABAB receptors (IC50: 43 μM).Fórmula:C5H14NO2PPureza:98%Forma y color:SolidPeso molecular:151.14CP-465022 (maleate)
CAS:CP-465022 Maleate: A selective noncompetitive AMPA antagonist with IC50 of 25 nM, showing anticonvulsant effects and useful for AMPA-related studies.Fórmula:C30H28ClFN4O5Forma y color:SolidPeso molecular:579.02TC-T 6000
CAS:TC-T 6000 (hENT4-IN-1) is an ENT4 inhibitor with vasodilator activity that inhibits hENT1 and hENT2 for the study of cancer and cardiovascular damage.Fórmula:C26H48N8O2Pureza:98.14%Forma y color:SolidPeso molecular:504.71GNE-6901
CAS:GNE-6901 is a selective GluN2A PAM.Fórmula:C18H17FN2O3SForma y color:SolidPeso molecular:360.4Diproteverine
CAS:<p>Diproteverine is a calcium antagonist, it has antianginal property.</p>Fórmula:C26H35NO4Pureza:98%Forma y color:SolidPeso molecular:425.56Nav1.1 activator 1
CAS:Nav1.1 activator 1 is a highly potent activator of Nav1.1 with BBB penetration.Fórmula:C24H23F3N4OPureza:98%Forma y color:SolidPeso molecular:440.46NMDA receptor antagonist 5
CAS:<p>Compound 10e: potent, non-toxic, brain-permeable NMDA receptor antagonist; key for neurological research.</p>Fórmula:C19H16BrNO2Forma y color:SolidPeso molecular:370.24(S)-(-)-HA 966
CAS:(S)-(-)-HA 966 is a NMDA receptor antagonist.Fórmula:C4H8N2O2Pureza:98%Forma y color:SolidPeso molecular:116.12Nav1.7-IN-2
CAS:Nav1.7-IN-2 is avoltage-gated sodium channels (Nav) inhibitor in particular Nav 1.7(IC50 of 80 nM).Fórmula:C22H22FN5O2Pureza:98%Forma y color:SolidPeso molecular:407.44KRP-199
CAS:<p>KRP-199, a highly potent and selective antagonist for the AMPA receptors, exhibits good neuroprotective effects in vivo.</p>Fórmula:C22H14F3N5O7Pureza:98%Forma y color:SolidPeso molecular:517.37GABAA receptor agent 8
CAS:<p>Compound 5e, a GABAA receptor modulator, shows potent anticonvulsant effects with low neurotoxicity for epilepsy research.</p>Fórmula:C19H16N4OForma y color:SolidPeso molecular:316.36Aprindine hydrochloride
CAS:<p>Aprindine HCl, a Class 1b antiarrhythmic, treats heart arrhythmias, outperforming digoxin in delaying atrial fibrillation. It's effective orally.</p>Fórmula:C22H31ClN2Forma y color:SolidPeso molecular:358.95UBP141
CAS:UBP141 is a antagonist of N-methyl-D-aspartate (NMDA) receptor.Fórmula:C21H18N2O5Pureza:98%Forma y color:SolidPeso molecular:378.38NHE3-IN-3
CAS:<p>NHE3-IN-3 inhibits human/rat NHE3 with pIC50s 6.2/6.6; 98% oral bioavailability in rats.</p>Fórmula:C16H16Cl2N2O2SForma y color:SolidPeso molecular:371.283-Chlorodiphenylamine
CAS:3-Cl-DPA, a cardiac troponin activator, acts by a mechanism distinct from bepridil or TFP.Fórmula:C12H10ClNForma y color:SolidPeso molecular:203.67Eltanexor Z-isomer
CAS:Eltanexor Z-isomer, less active than KPT-8602, inhibits Z138, MM1S, and 3T3 cells with IC50s: 100 nM-50 μM, <100 nM, >30 μM.Fórmula:C17H10F6N6OForma y color:SolidPeso molecular:428.29KMUP-4
CAS:Kmup-4 is an enhancer of cGMP activity and an aortic smooth muscle relaxant.Fórmula:C19H23N7O4Forma y color:SolidPeso molecular:413.43H100
CAS:H100 inhibits Cl- transport, mildly affects NaK2Cl cotransporter and Band 3 anion exchanger, not KCl cotransporter.Fórmula:C18H16N2O6SPureza:98%Forma y color:SolidPeso molecular:388.4LY 233536
CAS:LY 233536 is a novel, competitive antagonist of NMDA receptor.Fórmula:C12H19N5O2Pureza:98%Forma y color:SolidPeso molecular:265.31L-701252
CAS:L-701252, a potent glycine site NMDA receptor antagonist, exhibits an inhibition concentration (IC50) of 420 nM.Fórmula:C13H10ClNO3Pureza:97.7%Forma y color:White Crystalline SolidPeso molecular:263.68
