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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

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  • Imatinib Impurity E

    CAS:
    <p>Imatinib Impurity E, a derivative of orally taken Imatinib, inhibits tyrosine kinases BCR/ABL, PDGFR, c-kit, and SARS/MERS-CoV.</p>
    Fórmula:C52H48N12O2
    Forma y color:Solid
    Peso molecular:873.02
  • FITC-GW3965

    CAS:
    <p>FITC-GW3965: Fluorescent LXRβ agonist; FITC replaces trifluoromethyl in GW3965; used to probe LXRβ function.</p>
    Fórmula:C59H56N4O9S
    Forma y color:Solid
    Peso molecular:997.16
  • NU227326

    CAS:
    <p>NU227326 is a PROTAC degrader of indoleamine 2,3-dioxygenase 1 (IDO1) with a DC50 value of 4.5 nM. It effectively degrades IDO1 in U87 and GBM43 cells, with DC50 values of 7.1 nM and 11.8 nM, respectively. NU227326 exhibits favorable pharmacokinetic properties, with a plasma half-life of 5.7 hours and a brain tissue half-life of 11.8 hours. (Pink: ligand for target protein IDO1 ligand-1; Black: linker; Blue: ligand for E3 ligase Cereblon).</p>
    Fórmula:C53H61FN8O7
    Forma y color:Solid
    Peso molecular:941.099
  • Sofosbuvir impurity C

    CAS:
    <p>Sofosbuvir impurity C, a less active byproduct, inhibits HCV RNA replication and exhibits strong anti-HCV effects.</p>
    Fórmula:C22H29FN3O9P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:529.45
  • 1α, 25-Dihydroxy VD2-D6

    CAS:
    <p>1alpha, 25-Dihydroxy VD2-D6 is a deuterated form of vitamin D.</p>
    Fórmula:C28H44O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:434.68
  • Picornain 3C

    CAS:
    <p>Picornain 3C, a protease in picornaviruses, cleaves Gln-Gly bonds in poliovirus polyproteins and similar sites in others.</p>
    Forma y color:Solid
  • GF 109

    CAS:
    GF 109 is an inhibitor of ACE.
    Fórmula:C53H74N14O13
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1115.24
  • BChE-IN-36


    <p>hBChE-IN-4 (compound 40) serves as an effective activator for hCA and an inhibitor for BChE. It demonstrates affinity for various hCA subtypes with affinity constants (KA) of 266 nM for hCA I, 76.9 nM for hCA II, 918 nM for hCA IV, 893 nM for hCA VB, and 98.0 nM for hCA VII. Inhibition concentrations (IC50) for eeAChE and eqBChE are recorded at 72.1 nM and 4.2 nM, respectively. hBChE-IN-4 is non-cytotoxic and has demonstrated potential cognitive enhancement effects. It holds potential for research in neurodegenerative and other neuropsychiatric disorders.</p>
    Forma y color:Odour Solid
  • (±)10(11)-EpDPA

    CAS:
    <p>Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers.</p>
    Fórmula:C22H32O3
    Forma y color:Solid
    Peso molecular:344.495
  • Netupitant metabolite Netupitant N-oxide

    CAS:
    <p>Netupitant N-oxide is a highly selective antagonist of NK1 receptor, is Netupitant metabolite.</p>
    Fórmula:C30H32F6N4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:594.59
  • Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate

    CAS:
    <p>Preterramide C is a fungal metabolite that has been found inA.</p>
    Fórmula:C24H23N3O7
    Forma y color:Solid
    Peso molecular:465.46
  • Salinosporamide C

    CAS:
    <p>Salinosporamide C is a decarboxylated pyrrole analogue isolated from the marine Actinomycete Salinispora tropica.</p>
    Fórmula:C14H18ClNO3
    Forma y color:Solid
    Peso molecular:283.75
  • α-Amylase/α-Glucosidase-IN-12


    <p>α-Amylase/α-Glucosidase-IN-12 (compound 10k) is a dual inhibitor targeting α-glucosidase and α-amylase, with IC50 values of 34.52 nM and 24.62 nM, respectively. This inhibitor is designed based on [triazolo[4,3-b][1,2,4]triazine and holds potential for diabetes research.</p>
    Fórmula:C19H13F3N6OS
    Peso molecular:430.08236
  • (S)-ICMT-IN-3


    <p>'(S)-ICMT-IN-3 (compound ent 1-27) is an ICMT inhibitor with an IC50 value of 0.23 μM [1].'</p>
    Forma y color:Odour Solid
  • ML171

    CAS:
    <p>Compound PDK0326, with CAS No. 6631-94-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0326 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Fórmula:C14H11NOS
    Forma y color:Mustard-Colored Powder
    Peso molecular:241.3
  • Diaphorase

    CAS:
    <p>Diaphorase from anaerobic sludge catalyzes RDX biotransformation via denitrification.</p>
    Forma y color:Solid
  • H-Ile-Pro-Pro-OH hydrochloride

    CAS:
    <p>H-Ile-Pro-Pro-OH HCl, milk peptide, blocks ACE with 5 μM IC50. Antihypertensive.</p>
    Fórmula:C16H28ClN3O4
    Forma y color:Solid
    Peso molecular:361.86
  • 2-Methoxy-4-propylphenol

    CAS:
    <p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>
    Fórmula:C10H14O2
    Forma y color:Solid
    Peso molecular:166.22
  • 5β-Androstan-3β-ol-17-one

    CAS:
    <p>5β-Androstan-3β-ol-17-one (3β-Etiocholanolone; 5β-Epiandrosterone), a 5β-reduced steroid and a significant metabolic derivative of dehydroepiandrosterone (DHEA</p>
    Fórmula:C19H30O2
    Forma y color:Solid
    Peso molecular:290.44
  • Seocalcitol

    CAS:
    <p>Seocalcitol is an analog of vitamin D, binds vitamin D receptor protein from human osteosarcoma MG-63 cells(Kd : 0.27 nM).</p>
    Fórmula:C30H46O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:454.68
  • Lacto-N-biose I

    CAS:
    <p>Galβ1-3GlcNAc, a natural metabolite, is a substrate for H. pylori's α1,2-fucosyltransferase.</p>
    Fórmula:C14H25NO11
    Forma y color:Solid
    Peso molecular:383.35
  • 10-Formyldihydrofolate

    CAS:
    <p>10-Formyldihydrofolate is a Methotrexate metabolite. It inhibits thymidylate synthetase and glycinamide ribotide transformylase.</p>
    Fórmula:C20H21N7O7
    Forma y color:Solid
    Peso molecular:471.43
  • Streptolysin O

    CAS:
    <p>Streptolysin O: lyses cells, cardiotoxic, used for cell permeabilization, has active and inactive states.</p>
    Pureza:98%
    Forma y color:Solid
  • 7-Hydroxymethotrexate

    CAS:
    <p>7-Hydroxymethotrexate, major Methotrexate metabolite, inhibits dihydrofolate reductase and DNA synthesis by blocking folic acid conversion.</p>
    Fórmula:C20H22N8O6
    Pureza:99.72%
    Forma y color:Solid
    Peso molecular:470.44
  • (1S)-Calcitriol

    CAS:
    <p>(1S)-Calcitriol, a natural 1α,25(OH)2D3 metabolite, regulates VDR actions like keratinocyte growth inhibition.</p>
    Fórmula:C27H44O3
    Forma y color:Solid
    Peso molecular:416.646
  • FCPR03

    CAS:
    FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively.
    Fórmula:C15H19F2NO3
    Pureza:99.94%
    Forma y color:Solid
    Peso molecular:299.31
  • Ribulose, L-

    CAS:
    <p>Ribulose: key in pentose metabolism, aids L-ribose isomerase study, yeast engineering, and chiral compound research.</p>
    Fórmula:C5H10O5
    Forma y color:Solid
    Peso molecular:150.13
  • 2,8-Dihydroxyadenine

    CAS:
    <p>2,8-Dihydroxyadenine causes urinary crystals, kidney stones, and helps diagnose APRT deficiency.</p>
    Fórmula:C5H5N5O2
    Forma y color:Solid
    Peso molecular:167.128
  • γ-Glu-Gly TFA


    <p>γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite with a structure resembling GABA (γ-aminobutyric acid).</p>
    Forma y color:Liquid
  • Trimipramine N-oxide

    CAS:
    <p>Trimipramine N-oxide, a trimipramine metabolite, inhibits hNAT, hSERT, hDAT, and hOCT1/2 with IC50s 11.7-27.4 nM; for depression/anxiety research.</p>
    Fórmula:C20H26N2O
    Forma y color:Solid
    Peso molecular:310.43
  • CMI977

    CAS:
    <p>CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).</p>
    Fórmula:C16H19FN2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:322.33
  • Tetomilast

    CAS:
    <p>Tetomilast (OPC-6535) is a phosphodiesterase-4 (PDE4) inhibitor, potentially effective in treating inflammatory bowel disease (IBD) and chronic obstructive</p>
    Fórmula:C19H18N2O4S
    Forma y color:Solid
    Peso molecular:370.42
  • ZINC77292789

    CAS:
    <p>ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which</p>
    Fórmula:C33H38N2O13
    Pureza:99.24%
    Forma y color:Solid
    Peso molecular:670.66
  • trans-2-Hexadecenoyl-L-carnitine

    CAS:
    <p>trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite in urine[1].</p>
    Fórmula:C23H43NO4
    Forma y color:Solid
    Peso molecular:397.59
  • Hydroxycotinine

    CAS:
    <p>Hydroxycotinine is the main nicotine metabolite detected in smokers' urine.</p>
    Fórmula:C10H12N2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:192.218
  • L-Lactic acid-13C3

    CAS:
    <p>L-Lactic acid-13C3 is a stable isotope labeled L-Lactic acid analog. L-Lactic acid-13C3 can be used for lactate metabolism research.</p>
    Fórmula:C3H6O3
    Forma y color:Solid
    Peso molecular:93.055
  • IPI-9119

    CAS:
    <p>IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).</p>
    Fórmula:C24H19F2N5O5
    Pureza:99.81%
    Forma y color:Solid
    Peso molecular:495.43
  • Amidepsine A

    CAS:
    <p>Amidepsine A is a natural product for research related to life sciences. The catalog number is T22187 and the CAS number is 169181-28-6.</p>
    Forma y color:Solid
    Peso molecular:567.541
  • DOSPA (hydrochlorid)

    CAS:
    <p>DOSPA hydrochloride is a cationic lipid utilized in the formation of lipid nanoparticles.</p>
    Fórmula:C54H115Cl5N6O3
    Forma y color:Solid
    Peso molecular:1073.79
  • Abiraterone N-oxide

    CAS:
    <p>Abiraterone N-oxide is a metabolite of Abiraterone . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1] .</p>
    Fórmula:C24H31NO2
    Forma y color:Solid
    Peso molecular:365.51
  • Leuhistin

    CAS:
    Leuhistin is an aminopeptidases N inhibitor isolated from Bacillus laterosporus BMI156-14F1.
    Fórmula:C11H19N3O3
    Pureza:98%
    Forma y color:White To Off-White Solid
    Peso molecular:241.29
  • NCGC00092410

    CAS:
    <p>NCGC00092410 (ML008) is a glucocerebrosidase (GC) inhibitor with IC50 value of 31 nM.</p>
    Fórmula:C21H27N3O2
    Pureza:98.68%
    Forma y color:Solid
    Peso molecular:353.46
  • 3-HIB

    CAS:
    <p>3-HIB is a paracrine regulator of transendothelial fatty acid transport.</p>
    Fórmula:C4H7NaO3
    Forma y color:Solid
    Peso molecular:126.09
  • IDO1/TDO-IN-7


    <p>IDO1/TDO-IN-7 (Compound 43b), an isochinoline derivative, functions as a potent dual inhibitor of IDO1/TDO with IC50 values of 0.31 μM and 0.08 μM, respectively. Demonstrating favorable pharmacokinetics and strong antitumor efficacy in the B16-F10 tumor model, this compound also exhibits low toxicity.</p>
    Forma y color:Odour Solid
  • WH-15

    CAS:
    <p>WH-15: fluorogenic reporter for PLC-γ1, PLC-δ1, PLC-β2 with Km values of 49; 30, 86.1 µM. Cleaves to fluorescent 6-aminoquinoline for live cell imaging.</p>
    Fórmula:C31H43N2O18P3
    Forma y color:Solid
    Peso molecular:824.6
  • Anti-osteoporosis agent-10


    <p>Anti-osteoporosis agent-10 is an inhibitor of osteoporosis that suppresses the formation of osteoclasts with an IC50 of 0.042 μM. It also exhibits antagonistic activity towards PPARγ, with an EC50 value of 0.75 μM.</p>
    Forma y color:Odour Solid
  • AP-III-a4 hydrochloride

    CAS:
    <p>AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.</p>
    Fórmula:C31H44ClFN8O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:631.18
  • 3-Oxo-7-hydroxychol-4-enoic acid

    CAS:
    <p>3-Oxo-7-hydroxychol-4-enoic acid, a body metabolite, may signal bad liver disease prognosis.</p>
    Fórmula:C24H36O4
    Forma y color:Solid
    Peso molecular:388.54
  • PROTAC MAGL degrader-1


    <p>PROTACMAGLdegrader-1 is an orally active PROTAC agent that simultaneously targets both monoacylglycerol lipase (MAGL) and the E3 ubiquitin ligase MDM2. It functions by degrading MAGL and inhibiting the interaction between MDM2 and p53. Additionally, PROTACMAGLdegrader-1 has partial blood-brain barrier (BBB) penetration and can induce apoptosis in glioblastoma stem cells (GSC).</p>
    Forma y color:Odour Solid
  • Mersalyl

    CAS:
    Mersalyl is an organic mercurial diuretic.
    Fórmula:C13H16HgNNaO6
    Forma y color:Solid
    Peso molecular:505.854
  • SR-29065


    <p>SR-29065 is a selective agonist of REV-ERBα, utilized in the research of autoimmune disorders [1].</p>
    Forma y color:Odour Solid
  • LTA4H-IN-4


    <p>LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.</p>
  • Poly(4-vinylphenol)

    CAS:
    <p>Poly(4-vinylphenol) is an endogenous metabolite.</p>
    Fórmula:C10H17NO
    Pureza:98%
    Forma y color:Solid
    Peso molecular:167.252
  • Arofylline

    CAS:
    <p>Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.</p>
    Fórmula:C14H13ClN4O2
    Pureza:98.19%
    Forma y color:Solid
    Peso molecular:304.73
  • Micafungin metabolite M1

    CAS:
    <p>Micafungin metabolite M1 is an active metabolite of Micafungin, generated through metabolism by arylsulfatase, and exhibits antifungal activity. It can be utilized in research on deep fungal infections caused by Candida species (Candidiasis) and Aspergillus species (Aspergillosis).</p>
    Fórmula:C56H71N9O20
    Forma y color:Solid
    Peso molecular:1190.21
  • Cystocholic acid

    CAS:
    <p>Cystocholic acid is a metabolite of bile acids, possessing antimicrobial potential.</p>
    Fórmula:C27H45NO7
    Forma y color:Solid
    Peso molecular:495.65
  • Methylcardol triene

    CAS:
    <p>Methylcardol triene, a phenolic compound present in cashew nut shell liquid, demonstrates α-glucosidase inhibition (IC50= 39.6 µM) and exhibits schistosomicidal properties by eliminating 100% of adult S. mansoni worms within 24 hours at 100 and 200 µM concentrations. Moreover, it serves as a precursor for synthesizing mono- and bis-benzoxazines.</p>
    Fórmula:C22H32O2
    Forma y color:Solid
    Peso molecular:328.496
  • Lurasidone Metabolite 14283 hydrochloride

    CAS:
    Lurasidone Metabolite 14283 hydrochloride is a major active metabolite of Lurasidone.
    Fórmula:C28H37ClN4O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:545.14
  • Canine Factor Xa


    <p>CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.</p>
    Forma y color:Odour Solid
  • Dihydrozeatin riboside

    CAS:
    <p>Dihydrozeatin riboside is a cytokinin that can be isolated from Phaseolus vulgaris L.</p>
    Fórmula:C15H23N5O5
    Forma y color:Solid
    Peso molecular:353.37
  • Pepticinnamin E

    CAS:
    <p>Pepticinnamin E is a naturally occurring bisubstrate farnesyltransferase inhibitor.</p>
    Fórmula:C49H54ClN5O10
    Pureza:98%
    Forma y color:Solid
    Peso molecular:908.43
  • Carbonic anhydrase inhibitor 30


    <p>Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].</p>
    Fórmula:C23H22FN3O5S
    Forma y color:Solid
    Peso molecular:471.12642
  • (±)16-HDHA

    CAS:
    <p>(±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.</p>
    Fórmula:C22H32O3
    Forma y color:Solid
    Peso molecular:344.495
  • C14-490

    CAS:
    <p>C14-490 is an ionizable cationic lipid (pKa= 5.94) utilized in the synthesis of lipid nanoparticles (LNPs). These LNPs serve as a platform for subsequent gene editing studies in hematopoietic stem cells (HSCs) in utero. C14-490 LNPs encapsulate SpCas9 mRNA and TTR sgRNA, employing an optimized B5 formulation parameter, and are further enhanced by the surface attachment of CD45 antibody F(ab’)2 fragments to create Systemically Targeted Editing Mechanism LNPs (STEM LNPs).</p>
    Fórmula:C86H177N5O7
    Forma y color:Solid
    Peso molecular:1393.35
  • 1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

    CAS:
    <p>An endogenous blood metabolite, 1-heptadecanoyl-glycerophosphocholine, researches pregnancy/sepsis.</p>
    Fórmula:C25H52NO7P
    Forma y color:Solid
    Peso molecular:509.66
  • Dansylphenylalanine

    CAS:
    <p>Dansylphenylalanine is a typical fluorescent analyte.</p>
    Fórmula:C21H22N2O4S
    Forma y color:Solid
    Peso molecular:398.48
  • 10-FTHF

    CAS:
    <p>10-FTHF is a donor of formyl groups in anabolism used as a substrate in formyltransferase reactions, which is important in purine biosynthesis.</p>
    Fórmula:C20H23N7O7
    Forma y color:Solid
    Peso molecular:473.44
  • Galactosylhydroxylysine

    CAS:
    <p>Galactosylhydroxylysine, a bone collagen breakdown product, is released during bone resorption and excreted in urine.</p>
    Fórmula:C12H24N2O8
    Forma y color:Solid
    Peso molecular:324.33
  • N-Formyl-2-aminophenol

    CAS:
    <p>N-Formyl-2-aminophenol (N-(2-hydroxyphenyl)methanamide) is a bacterial secondary metabolite found in P. chrysogenum and exhibits antioxidant properties.</p>
    Fórmula:C7H7NO2
    Forma y color:Solid
    Peso molecular:137.136
  • Rat Factor Xa


    <p>RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.</p>
    Forma y color:Odour Solid
  • ACSS2-IN-2

    CAS:
    <p>MTB-9655 inhibits ACSS2 with 3.8 nM IC50, useful in research of viral, metabolic, neuropsychiatric diseases, inflammation, and cancer.</p>
    Fórmula:C21H19F2N3O4
    Pureza:99.5%
    Forma y color:Soild
    Peso molecular:415.39
  • MK-8262

    CAS:
    <p>MK-8262: oral CETP inhibitor, potent (IC50 = 53 nM, log D = 5.3), may impact HDL/LDL and CHD research.</p>
    Fórmula:C35H25F9N2O5
    Forma y color:Solid
    Peso molecular:724.58
  • ROR1 ligand-1


    <p>ROR1ligand-1 (9-1) serves as the ligand for PROTAC ROR1 degrader-1. By linking with ligands of either the VHL type or CRBN, the first selective and efficient ROR1 PROTAC molecule was designed and synthesized.</p>
    Fórmula:C23H30BrN7
    Forma y color:Solid
    Peso molecular:484.44
  • N-Acetylhexosamine kinase (NahK)

    CAS:
    <p>NahK phosphorylates GlcNAc/GalNAc at C1 using ATP to form GlcNAc-1P/GalNAc-1P.</p>
    Forma y color:Solid
  • Laprafylline

    CAS:
    <p>Laprafylline: Xanthine derivative, blocks bronchoconstriction &amp; tumor growth, competes with serotonin, resists histamine at high levels.</p>
    Fórmula:C29H36N6O2
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:500.64
  • Caffeoylcalleryanin

    CAS:
    <p>Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.</p>
    Fórmula:C22H24O11
    Forma y color:Solid
    Peso molecular:464.4
  • DSPE-PEG-Maleimide (MW 3400) ammonium


    <p>DSPE-PEG-Maleimide (MW 3400) ammonium combines DSPE phospholipids with maleimide for the preparation of nanostructured lipid carriers. It is applicable in drug delivery research.</p>
    Forma y color:Odour Solid
  • Crotonyl-CoA tetrasodium


    <p>Crotonyl-CoA tetrasodium is the tetrasodium salt form of Crotonyl-CoA. It serves as an intermediate in butyrate fermentation and in the metabolism of lysine and tryptophan. This compound plays a crucial role in the metabolism of fatty acids and amino acids.</p>
    Fórmula:C25H36N7Na4O17P3S
    Forma y color:Solid
    Peso molecular:923.54
  • 6-hydroxy Chlorzoxazone

    CAS:
    <p>6-hydroxy Chlorzoxazone, a chlorzoxazone metabolite, is formed in the liver via CYP2E1.</p>
    Fórmula:C7H4ClNO3
    Forma y color:White To Pink
    Peso molecular:185.56
  • L-Glutamic acid ammonium

    CAS:
    <p>L-Glutamic acid ammonium is an excitatory neurotransmitter.</p>
    Fórmula:C5H12N2O4
    Forma y color:Solid
    Peso molecular:164.16
  • LVGRQLEEFL (mouse) (TFA)


    <p>G* peptide, also known as LVGRQLEEFL (mouse) TFA, is a segment corresponding to amino acids 113 to 122 ([113,122] apoJ) of apolipoprotein J.</p>
    Forma y color:Odour Solid
  • Lumisterol

    CAS:
    <p>Lumisterol, a steroid, is anti-UVB and inhibits cell growth; it's a (9β,10α)-stereoisomer of Ergosterol.</p>
    Fórmula:C28H44O
    Forma y color:Solid
    Peso molecular:396.659
  • Hydroxy bosentan

    CAS:
    <p>Hydroxy bosentan (Ro 48-5033), a Bosentan metabolite, is liver-processed with 10-20% of its activity.</p>
    Fórmula:C27H29N5O7S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:567.61
  • Rubrofusarin 6-O-β-D-glucopyranoside

    CAS:
    <p>Rubrofusarin 6-O-β-D-glucopyranoside, a glycosidic derivative of Rubrofusarin, functions as an inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50</p>
    Fórmula:C21H22O10
    Forma y color:Solid
    Peso molecular:434.39
  • Aldosterone-d8

    CAS:
    <p>Aldosterone D8, a deuterium-labeled variant of Aldosterone produced in the adrenal zona glomerulosa, regulates blood pressure.</p>
    Fórmula:C21H28O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:368.49
  • (S)-Higenamine hydrobromide

    CAS:
    <p>(S)-Higenamine hydrobromide, S-enantiomer for benzylisoquinoline synthesis, results from dopamine and 4-HPAA condensation by NCS.</p>
    Fórmula:C16H18BrNO3
    Forma y color:Solid
    Peso molecular:352.22
  • Tauro-α-muricholic Acid (sodium salt)

    CAS:
    <p>Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary</p>
    Fórmula:C26H44NNaO7S
    Forma y color:Solid
    Peso molecular:537.69
  • 16α-Hydroxydehydroepiandrosterone-d5


    <p>16α-Hydroxydehydroepiandrosterone-d5 (16α-Hydroxy-DHEA-d5) is the deuterated form of 16α-Hydroxydehydroepiandrosterone.</p>
    Fórmula:C19H23D5O3
    Forma y color:Solid
    Peso molecular:309.45
  • hCA/VEGFR-2-IN-2


    <p>Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and</p>
    Fórmula:C23H26N6O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:498.55
  • Isbufylline

    CAS:
    <p>Isbufylline can exert significant anti-inflammatory actions, in addition to its bronchodilator activity.</p>
    Fórmula:C11H16N4O2
    Pureza:90% - 97.59%
    Forma y color:Solid
    Peso molecular:236.27
  • hCYP3A4-IN-1


    <p>hCYP3A4-IN-1 (compound C6) is a potent, orally active inhibitor of hCYP3A4, exhibiting IC50 values of 43.93 nM in human liver microsomes (HLMs) and 153.00 nM in</p>
    Forma y color:Odour Solid
  • hCAIX/XII-IN-14


    <p>hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.</p>
    Fórmula:C16H14F3N3O4S
    Forma y color:Solid
    Peso molecular:401.36
  • MJ33-OH lithium

    CAS:
    <p>MJ33-OH lithium is a metabolite of MJ33.</p>
    Fórmula:C22H43F3LiO7P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:514.48
  • VM4-037

    CAS:
    <p>VM4-037 is a PET imaging agent used for carbonic anhydrase IX.</p>
    Fórmula:C26H29FN6O7S2
    Forma y color:Solid
    Peso molecular:620.67
  • Tuftsin diacetate

    CAS:
    <p>Tuftsin diacetate, Thr-Lys-Pro-Arg, activates macrophages/microglia; it's in immunoglobulin G's Fc and boosts immunity.</p>
    Fórmula:C25H48N8O10
    Pureza:98%
    Forma y color:Solid
    Peso molecular:620.7
  • Theodrenaline hydrochloride

    CAS:
    <p>Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.</p>
    Fórmula:C17H22ClN5O5
    Pureza:98% - 98.18%
    Forma y color:Soild
    Peso molecular:411.84
  • Galactonic acid

    CAS:
    <p>Galactonic acid, derived from galactose metabolism, is converted from galactonolactone.</p>
    Fórmula:C6H12O7
    Forma y color:Solid
    Peso molecular:196.16
  • α-Glucosidase-IN-84


    <p>α-Glucosidase-IN-84 (Compound 7j) is a competitive inhibitor of α-glucosidase, exhibiting an IC50 of 50 μM and a Ki of 32 μM. It shows potential for application in metabolic disease research, particularly in studies related to type 2 diabetes.</p>
    Fórmula:C25H29N7O3S
    Forma y color:Solid
    Peso molecular:507.608
  • PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)

    CAS:
    <p>PIP3, a minor yet critical phospholipid for cell signaling, resists PLC cleavage and anchors PH domain proteins, affecting cytoskeletal and membrane dynamics.</p>
    Fórmula:C21H45NO22P4
    Forma y color:Solid
    Peso molecular:787.471
  • Oleic Acid-2,6-diisopropylanilide

    CAS:
    <p>Oleic acid-2,6-diisopropylanilide: ACAT inhibitor, IC50 7 nM; lowers LDL &amp; raises HDL in high-fat fed rabbits/rats at 0.05%.</p>
    Fórmula:C30H51NO
    Forma y color:Solid
    Peso molecular:441.744