Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(271 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(98 productos)
- Lípido(58 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(165 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8628 productos de "Metabolismo"
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Ninerafaxstat trihydrochloride
CAS:<p>Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation.</p>Fórmula:C22H32Cl3N3O5Pureza:99.71%Forma y color:SoildPeso molecular:524.87γ-Globulins from human blood
CAS:<p>γ-Globulins, a protein fraction found in human blood, comprise a class of proteins with potent antibody activity that safeguards against bacterial and viral</p>Forma y color:SolidFXIIa-IN-4
<p>FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.</p>Fórmula:C11H9FN4O3Peso molecular:264.065872-NP-AMOZ
CAS:<p>2-NP-AMOZ, a 2-nitrophenyl AMOZ, detects protein-bound AMOZ, a Furaltadone metabolite.</p>Fórmula:C15H18N4O5Forma y color:SolidPeso molecular:334.33LTA4H-IN-4
<p>LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.</p>Fmoc-Cys-Asp10 TFA
Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker involved in synthesizing releasable oligopeptide linkers. These releasable linkers are used to deliver drugs to fracture-targeting oligopeptides, thereby reducing the healing time of fractured femurs.Fórmula:C60H68F3N11O36SPeso molecular:1607.35012ACAT-IN-2
CAS:<p>ACAT-IN-2, from EP1236468A1 (ex. 187), inhibits ACAT and blocks NF-κB transcription.</p>Fórmula:C29H44N2O4SForma y color:SolidPeso molecular:516.74GP4G
CAS:<p>GP4G, from Artemia salina cysts, regulates epithelial cells & hair growth.</p>Fórmula:C20H28N10O21P4Forma y color:SolidPeso molecular:868.39Cytochrome P450 reductase
CAS:<p>Cytochrome P450 reductase, a NADPH-cytochrome reductase, facilitates an optimal conformation of aromatase for substrate binding [1].</p>Forma y color:Solid9AzNue5Ac
CAS:<p>9AzNue5Ac is a Neu5Ac analog that is metabolized in vivo in living cells and in mice.9AzNue5Ac binds to sialoglycans.</p>Fórmula:C11H18N4O8Pureza:≥98%Forma y color:SolidPeso molecular:334.28MTHFD2-IN-3
<p>MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activity</p>Fórmula:C22H19NO7SForma y color:SolidPeso molecular:441.456β-hydroxy Eplerenone
CAS:<p>6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone .1 It is formed from eplerenone by the cytochrome P450 (CYP</p>Fórmula:C24H30O7Forma y color:SolidPeso molecular:430.497DSPE-PEG2000-YIGSR
<p>DSPE-PEG2000-YIGSR is a PEG compound composed of DSPE and the biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin-binding protein (LBP), enhancing the adhesion and proliferation of various cell types, including endothelial cells, fibroblasts, and smooth muscle cells. DSPE-PEG2000-YIGSR is applicable in drug delivery.</p>Forma y color:Odour SolidLodenafil carbonate
CAS:<p>Lodenafil carbonate is a prodrug, orally used as a PDE5 inhibitor for ED treatment.</p>Fórmula:C47H62N12O11S2Forma y color:SolidPeso molecular:1035.21Rennin
CAS:<p>Rennin or Chymosin, a stomach enzyme in some animals, curdles milk by cleaving K-casein; key in cheese making.</p>Forma y color:SolidATX inhibitor 7
CAS:<p>ATX inhibitor 7 is a autotaxin inhibitor and shows good oral exposure.</p>Fórmula:C21H22F3N7O2Forma y color:SolidPeso molecular:461.449Adefovir diphosphate 2TEA
<p>Adefovir diphosphate 2TEA,a metabolite of Adefovir, an oral reverse transcriptase inhibitor with antiviral activity against herpes, hepatitis B, and HIV.</p>Fórmula:C20H43N7O7P2Pureza:98.33%Forma y color:SolidPeso molecular:555.55Sofosbuvir impurity C
CAS:<p>Sofosbuvir impurity C, a less active byproduct, inhibits HCV RNA replication and exhibits strong anti-HCV effects.</p>Fórmula:C22H29FN3O9PPureza:98%Forma y color:SolidPeso molecular:529.45DSPE-PEG5000-VIP
<p>DSPE-PEG5000-PP1 is a PEG compound composed of DSPE and the cell-penetrating peptide (TAT) peptide. DSPE-PEG2000-TAT is applicable for drug delivery.</p>Forma y color:Odour SolidCarbazeran citrate
CAS:aldehyde oxidase (AO) substrateFórmula:C24H32N4O11Pureza:98%Forma y color:SolidPeso molecular:552.53SDUY817
<p>SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.</p>Fórmula:C18H16IN3O3Forma y color:SolidPeso molecular:449.241α, 25-Dihydroxy VD2-D6
CAS:<p>1alpha, 25-Dihydroxy VD2-D6 is a deuterated form of vitamin D.</p>Fórmula:C28H44O3Pureza:98%Forma y color:SolidPeso molecular:434.68BDM_92499
<p>BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.</p>Forma y color:Odour SolidLantanose A
CAS:Lantanose A is a bioactive chemical from Lantana cumara roots.Fórmula:C30H52O26Pureza:98%Forma y color:SolidPeso molecular:828.722,5-Anhydro-D-glucitol-1,6-diphosphate
CAS:<p>2,5-Anhydro-D-glucitol-1,6-diphosphate mildly stimulates yeast Pyruvate Kinase; it's an analogue of a potent activator.</p>Fórmula:C6H14O11P2Forma y color:SolidPeso molecular:324.12Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate
CAS:<p>Preterramide C is a fungal metabolite that has been found inA.</p>Fórmula:C24H23N3O7Forma y color:SolidPeso molecular:465.46Coenzyme Q6
CAS:<p>Coenzyme Q6, also Ubiquinone 30, is a benzoquinone lipid aiding respiration and acting as an antioxidant.</p>Fórmula:C39H58O4Forma y color:SolidPeso molecular:590.88SHP2 protein degrader-2
CAS:SHP2 protein degrader-2 (SHP2-D26), a PROTAC degrader targeting the SHP2 protein, effectively diminishes its expression levels across various cancer cell typesFórmula:C56H79ClN12O6S2Forma y color:SolidPeso molecular:1115.89ZINC77292789
CAS:ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer whichFórmula:C33H38N2O13Pureza:99.24%Forma y color:SolidPeso molecular:670.66α-Glucosidase-IN-84
<p>α-Glucosidase-IN-84 (Compound 7j) is a competitive inhibitor of α-glucosidase, exhibiting an IC50 of 50 μM and a Ki of 32 μM. It shows potential for application in metabolic disease research, particularly in studies related to type 2 diabetes.</p>Fórmula:C25H29N7O3SForma y color:SolidPeso molecular:507.608DSPE-PEG5000-R8
<p>DSPE-PEG5000-R8 is a PEG compound composed of DSPE and the cell-penetrating peptide (R8). It is utilized for drug delivery applications.</p>Forma y color:Odour Solidα-D-Glucose-1-phosphate disodium hydrate
CAS:<p>α-D-Glucose-1-phosphate disodium hydrate serves multiple roles in medical and biochemical applications, including as a precursor in the synthesis of glucuronic</p>Fórmula:C6H15Na2O11PForma y color:SolidPeso molecular:340.13Resveratrol-3-O-sulfate sodium
CAS:<p>Resveratrol-3-O-sulfate reduces IL-1α/β, IL-6, TNF-α in LPS-stimulated U-937 cells, inhibits Caco-2 cell growth, induces apoptosis, and binds mitoNEET.</p>Fórmula:C14H11NaO6SForma y color:SolidPeso molecular:330.2910 FTHF disodium
CAS:<p>10 FTHF disodium (10-Formyltetrahydrofolic acid disodium) is a form of tetrahydrofolate that is involved in the synthesis of purine compounds.</p>Fórmula:C20H21N7Na2O7Forma y color:SolidPeso molecular:517.4Rostratin C
CAS:<p>Rostratin C, a cytotoxic disulfide, exhibits in vitro cytotoxicity against human colon carcinoma (HCT-116), demonstrating an IC50 value of 0.76 μg/mL.</p>Fórmula:C20H24N2O8S2Forma y color:SolidPeso molecular:484.54Galactosylhydroxylysine
CAS:<p>Galactosylhydroxylysine, a bone collagen breakdown product, is released during bone resorption and excreted in urine.</p>Fórmula:C12H24N2O8Forma y color:SolidPeso molecular:324.33Phytin
CAS:<p>Phytin has a wide range of applications in life science related research.</p>Fórmula:C6H6CaMgO24P6Forma y color:White PowderPeso molecular:712.32HIV-IN-9
<p>HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.</p>Forma y color:Odour SolidLurasidone Metabolite 14283 hydrochloride
CAS:Lurasidone Metabolite 14283 hydrochloride is a major active metabolite of Lurasidone.Fórmula:C28H37ClN4O3SPureza:98%Forma y color:SolidPeso molecular:545.143-HIB
CAS:<p>3-HIB is a paracrine regulator of transendothelial fatty acid transport.</p>Fórmula:C4H7NaO3Forma y color:SolidPeso molecular:126.09Monoglyceride lipase
CAS:<p>Monoglyceridelipase is a crucial enzyme involved in lipid metabolism, catalyzing the hydrolysis of monoglycerides (especially 2-AG, or 2-arachidonoylglycerol) into glycerol and free fatty acids. By regulating the levels of 2-AG, this enzyme impacts neural signaling, pain perception, inflammatory responses, and metabolic processes.</p>Forma y color:SolidHydroxy bosentan
CAS:<p>Hydroxy bosentan (Ro 48-5033), a Bosentan metabolite, is liver-processed with 10-20% of its activity.</p>Fórmula:C27H29N5O7SPureza:98%Forma y color:SolidPeso molecular:567.61[(3R)-3-Hydroxydodecanoyl]-L-carnitine
CAS:<p>[(3R)-3-Hydroxydodecanoyl]-L-carnitine is an endogenous metabolite[1].</p>Fórmula:C19H37NO5Forma y color:SolidPeso molecular:359.50Tuftsin diacetate
CAS:<p>Tuftsin diacetate, Thr-Lys-Pro-Arg, activates macrophages/microglia; it's in immunoglobulin G's Fc and boosts immunity.</p>Fórmula:C25H48N8O10Pureza:98%Forma y color:SolidPeso molecular:620.7PP5-IN-2
<p>PP5-IN-2, a selective and orally active inhibitor of protein phosphatase 5 (PP5), exhibits an IC 50 of 0.9 μM. This compound activates p53 and leads to the downregulation of cyclin D1 and MGMT, thereby inducing cell cycle arrest and reversing Temozolomide (TMZ) resistance in the U87 MG cell line. Additionally, PP5-IN-2 has demonstrated effective inhibition of tumor growth in the xenograft mouse model.</p>Fórmula:C16H15NO4Forma y color:SolidPeso molecular:285.291-Methylhistamine
CAS:<p>2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine is a histamine metabolite.</p>Fórmula:C6H11N3Pureza:98%Forma y color:SolidPeso molecular:125.1716Penicillinase
CAS:<p>Penicillinase is a β-lactamase and secretory enzyme capable of degrading and inactivating penicillin and similar compounds.</p>Forma y color:SolidN-Nitrosoglyphosate sodium
CAS:<p>N-Nitrosoglyphosate sodium, a nitrosamine degradation product and synthetic impurity of glyphosate herbicide [1], is a chemical compound resulting from the</p>Fórmula:C3H6N2NaO6PForma y color:SolidPeso molecular:220.05Ophiobolin A
CAS:<p>Ophiobolin A: Fungal metabolite, phytotoxin, inhibits calmodulin-activated phosphodiesterase (IC50: 9μM), with antimicrobial and anticancer properties.</p>Fórmula:C25H36O4Pureza:98%Forma y color:SolidPeso molecular:400.559C-Type Natriuretic Peptide (1-53), Porcine, Rat,mouse
CAS:<p>C-Type Natriuretic Peptide (1-53), from porcine, rat, and mouse sources, serves as an activator of particulate guanylate cyclase B (pGC-B), prominently found in endothelial cells, kidneys, and the heart. This peptide efficiently mediates a potent anti-fibrotic effect in human cardiac and renal fibroblasts through the production of the second messenger cGMP.</p>Forma y color:SolidCZP-IN-1
CZP-IN-1 (compound SH-1) is an inhibitor targeting the pathogen Trypanosoma cruzi protease (CZP) without affecting cathepsin L (IC50=28 nM). This compound is applicable in Chagas disease research.Fórmula:C20H26N4O4SForma y color:SolidPeso molecular:418.51DSPE-PEG2000-APRPG
<p>DSPE-PEG2000-APRPG is a PEG compound composed of DSPE and the APRPG peptide. It is utilized in drug delivery applications.</p>Forma y color:Odour Solidα-Glucosidase-IN-73
<p>α-Glucosidase-IN-73 (compound 16b), an α-Glucosidase inhibitor, exhibits an IC 50 value of 0.158 μM and possesses the ability to activate PPAR γ. This compound is applicable in studies focusing on anti-diabetic and anti-inflammatory treatments.</p>Fórmula:C24H21N3O2SForma y color:SolidPeso molecular:415.51DSPE-PEG1000-pPB
<p>DSPE-PEG1000-pPB is a PEG compound consisting of DSPE and a cyclic oligopeptide (pPB). The pPB component exhibits a strong binding affinity to PDGFRβ, which is overexpressed in activated hepatic stellate cells (HSC). DSPE-PEG1000-pPB is applicable for drug delivery.</p>Forma y color:Odour SolidCoprosterol
CAS:<p>Coprosterol is a stanol formed from the biohydrogenation of cholesterol as a biomarker for the presence of human faecal matter in the environment.</p>Fórmula:C27H48OForma y color:SolidPeso molecular:388.673-Nitro-L-tyrosine ethyl ester hydrochloride
<p>3-Nitro-L-tyrosine ethyl ester hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T124433.</p>Fórmula:C11H15ClN2O5Forma y color:SolidPeso molecular:290.7Endoglycoceramidase II (EGCase II)
CAS:<p>EGCase II is an enzyme breaking down the glycan-ceramide bond in glycosphingolipids.</p>Forma y color:SolidMorin 3-O-β-D-glucopyranoside
CAS:<p>Morin 3-O-β-D-glucopyranoside, a natural flavonoid, exhibits antifungal, anticancer, and antioxidant properties.</p>Fórmula:C21H20O12Forma y color:SolidPeso molecular:464.384-Ethylbenzonitrile
CAS:<p>4-Ethylbenzonitrile is a micromolar level inhibitor of Cytochrome P450 2A6 with an IC50 value of 7.4 渭M.</p>Fórmula:C9H9NForma y color:SolidPeso molecular:131.17Desbutyl Lumefantrine
CAS:<p>Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity.</p>Fórmula:C26H24Cl3NOPureza:98%Forma y color:SolidPeso molecular:472.833-O-Dihydro-p-coumaroyltohogenol
<p>3-O-Dihydro-p-coumaroyltohogenol functions as a PTP1B inhibitor (IC50 = 6.27 μM), exhibiting anti-diabetic and anti-obesity activities.</p>Fórmula:C39H60O5Forma y color:SolidPeso molecular:608.89CAXII-IN-2
<p>CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.</p>Fórmula:C16H13FNO4PForma y color:SolidPeso molecular:333.05662ADP-specific glucokinase
CAS:<p>ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.</p>Forma y color:SolidCE(20:5(5Z,8Z,11Z,14Z,17Z)
CAS:CE(20:5(5Z,8Z,11Z,14Z,17Z) is an endogenous metabolite.Fórmula:C47H74O2Pureza:98%Forma y color:SolidPeso molecular:671.09XW-032
<p>XW-032 is an apo-IDO1 inhibitor with an IC50 of 21 nM. In the CT26 syngeneic mouse model, XW-032 demonstrates significant in vivo antitumor efficacy with a TGI of 63%, showing potential for cancer research applications.</p>Forma y color:Odour Solidm-Tyramine
CAS:<p>m-Tyramine has effects on the adrenergic and dopaminergic receptor.m-Tyramine is an endogenous trace amine neuromodulator.</p>Fórmula:C8H11NOPureza:98%Forma y color:SolidPeso molecular:137.18IONIS PTP1BRx
CAS:<p>IONIS PTP1BRx (ISIS 404173) acts as an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). This compound exhibits anti-diabetic properties, making it suitable for research into insulin resistance related to obesity and type 2 diabetes.</p>Forma y color:Solidm-PEG8-DSPE
<p>m-PEG8-DSPE is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>Fórmula:C59H116NO17PPureza:98%Forma y color:SolidPeso molecular:1142.52(S)-Salsolidine
CAS:<p>(S)-Salsolidine is a MAO inhibitor with Ki 63μM; its R enantiomer is more effective, Ki 26μM.</p>Fórmula:C12H17NO2Forma y color:SolidPeso molecular:207.27Antibacterial agent 237
<p>Anti bacterial agent 237 (compound Ru-8) acts as a potent antibacterial agent against Staphylococcus aureus, exhibiting minimum inhibitory concentrations (MICs) ranging from 0.78 to 1.56 μg/mL. It works by disrupting bacterial cell membranes, altering their permeability, and inducing the production of reactive oxygen species, which leads to bacterial cell death without promoting resistance. Additionally, Anti bacterial agent 237 demonstrates low hemolytic toxicity towards rabbit erythrocytes and Raw 264.7 cells. It has shown significant antibacterial activity in models of skin wound infections in mice and larval infections by the greater wax moth, effectively combating Staphylococcus aureus infections.</p>Fórmula:C65H69Cl3N10RuS2Forma y color:SolidPeso molecular:1261.87Trimetazidine-N-oxide
CAS:<p>Trimetazidine-N-oxide, main active metabolite of Trimetazidine, blocks 3-ketoyl CoA thiolase (IC50: 75nM) and has multiple protective properties.</p>Fórmula:C14H22N2O4Pureza:98%Forma y color:SolidPeso molecular:282.34CAY10434
CAS:<p>CAY10434, a potent CYP4A hydroxylase inhibitor, has an IC50 of 8.8 nM and boosts angiotensin II contraction, Emax 6764 mg.</p>Fórmula:C17H25N3OPureza:99.85%Forma y color:SolidPeso molecular:287.4NAD Synthetase
CAS:NAD Synthetase is responsible for the final step in the synthesis of Nicotinamide Adenine Dinucleotide (NAD). The enzyme sourced from Escherichia coli exhibits Km values of 200 μM for NAD, 11 μM for ATP, and 0.65 μM for ammonia. Conversely, NAD Synthetase derived from yeast demonstrates Km values of 170 μM for NAD, 190 μM for ATP, and 64 μM for ammonia. This enzyme is applicable in enzymatic assays for ATP, ammonia, urea, or creatinine and can also be used in enzymatic recycling methods. Additionally, NAD Synthetase holds potential for research into metabolic diseases, cancer, aging, and neurodegenerative disorders.Forma y color:SolidCarbonic anhydrase inhibitor 29
<p>Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.</p>Forma y color:Odour SolidLysophosphatidylethanolamines (egg)
CAS:<p>Lysophosphatidylethanolamines (egg) are the partial hydrolysis products of phosphatidylethanolamine.</p>Forma y color:SolidRORγt inhibitor 1
CAS:<p>RORγt inhibitor 1 is a RORγt allosteric inhibitor with an IC 50 value of 1 nM.</p>Fórmula:C23H21ClFN3O4Forma y color:SolidPeso molecular:457.89Alterporriol B
CAS:<p>Alterporriol B is a biochemical.</p>Fórmula:C32H26O13Forma y color:SolidPeso molecular:618.547ATP dipotassium
CAS:<p>ATP dipotassium is key for energy storage, metabolism, cellular processes, and as a signaling molecule for immunity and inflammation.</p>Fórmula:C10H14K2N5O13P3Forma y color:SolidPeso molecular:583.36Seocalcitol
CAS:<p>Seocalcitol is an analog of vitamin D, binds vitamin D receptor protein from human osteosarcoma MG-63 cells(Kd : 0.27 nM).</p>Fórmula:C30H46O3Pureza:98%Forma y color:SolidPeso molecular:454.68h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Fórmula:C22H30Cl2N6O3Forma y color:SolidPeso molecular:497.42Tyrosine decarboxylase
CAS:<p>TDC, a PLP-dependent enzyme, removes carboxyl groups from tyrosine, producing tyramine and CO2, found in plants, insects, and microbes.</p>Forma y color:SolidD-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP)
<p>D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP), belonging to the CAZy glycoside hydrolase family GH112, plays a pivotal role in</p>Forma y color:SolidROR1 ligand-1
<p>ROR1ligand-1 (9-1) serves as the ligand for PROTAC ROR1 degrader-1. By linking with ligands of either the VHL type or CRBN, the first selective and efficient ROR1 PROTAC molecule was designed and synthesized.</p>Fórmula:C23H30BrN7Forma y color:SolidPeso molecular:484.44FXR antagonist 2
CAS:<p>Compound A-26, a diarylamide FXR blocker, may aid hyperlipidemia and diabetes type 2 research.</p>Fórmula:C22H26Cl2N2O2Forma y color:SolidPeso molecular:421.36Tpp-CAQK
<p>Tpp-CAQK, a specially engineered mitochondrial compound, has been shown to improve phagocytosis of myelin debris by macrophages, reduce mitochondrial dysfunction and pro-inflammatory features, and enhance tissue repair and functional recovery in mice after spinal cord injury.</p>Fórmula:C40H54BrN6O7PSForma y color:SolidPeso molecular:873.84PKR activator 4
CAS:<p>PKR activator 4 (example 7A), a potent activator of pyruvate kinase R (PKR), holds promise for blood disorder research [1].</p>Fórmula:C18H24N6O2SSiForma y color:SolidPeso molecular:416.571-Arachidonoyl Lysophosphatidic Acid (ammonium salt)
CAS:<p>1-Arachidonoyl LPA: phospholipid with arachidonic acid, sn-1, LPA2 receptor binder, EC50 ~10 nM, modulates cytokine secretion, affects cell differentiation.</p>Fórmula:C23H42NO7PForma y color:SolidPeso molecular:475.563IONIS PTP1BRx sodium
<p>IONIS PTP1BRx (ISIS 404173) sodium, an antisense inhibitor of protein tyrene phosphatase 1B (PTP-1B), exhibits antidiabetic properties. This compound is utilzed in researching insulin resistance and type 2 diabetes mellitus associated with obesity.</p>Forma y color:Odour SolidLY 295427
CAS:<p>LY 295427 is a bioactive chemical.</p>Fórmula:C30H52OForma y color:SolidPeso molecular:428.73Maurocalcine TFA
<p>Maurocalcine TFA acts as an agonist for ryanodine receptor (RyR) channels 1, 2, and 3, demonstrating cell-penetrating capabilities. It induces binding of [3H]ryanodine to RyR1 with an EC50 of 2558 nM and exhibits an apparent affinity of 14 nM for RyR2. This compound is applicable for in vivo cell tracking or other cellular imaging techniques.</p>Fórmula:C156H270N56O46S6·xC2HF3O2Forma y color:SolidPeso molecular:3858.55 (free base)A32390A
CAS:<p>A32390A, an antibiotic inhibitor, shows antimicrobial activity against gram-positive bacteria and fungi.</p>Fórmula:C18H24N2O8Forma y color:SolidPeso molecular:396.39NU223612
CAS:<p>"NU223612 is a potent IDO1-degrading PROTAC with Kd 640 nM, binds CRBN at 290 nM, and crosses the BBB."</p>Fórmula:C49H55FN6O9Forma y color:SolidPeso molecular:890.99DSPE-PEG2000-KAA
<p>DSPE-PEG2000-KAA is a PEG compound composed of DSPE and the CKAAKNK (KAA) peptide. The CKAAKNK peptide specifically binds to the tumor vasculature of RIP-Tag2 transgenic mice. DSPE-PEG2000-KAA can be used for drug delivery.</p>Forma y color:Odour SolidEpoxide hydrolase
CAS:<p>Epoxide hydrolase, an enzyme responsible for catalyzing the reaction of epoxides with water to convert epoxy groups into diols, plays a crucial role in the metabolism of environmental pollutants and lipids. It is instrumental in detoxification, inflammatory responses, and regulating the health of the cardiovascular system. Additionally, Epoxide hydrolase is used in asymmetric catalytic reactions, such as the asymmetric ring-opening of epoxides, which are important for the synthesis of chiral pharmaceutical molecules.</p>Forma y color:SolidD-Erythrose 4-phosphate sodium
CAS:<p>D-erythrose 4-sodium phosphate: sodium salt of monosaccharide, made from erythritol via 3 isomerases.</p>Fórmula:C4H8NaO7PPureza:98%Forma y color:SolidPeso molecular:222.07NADP+ (sodium salt hydrate)
CAS:<p>NADP+ is the oxidized cofactor form of NADPH, vital for cell survival, redox balance, and signaling; synthesized from NAD+ and ATP.</p>Fórmula:C21H30N7NaO18P3Forma y color:SolidPeso molecular:784.413PKM2 activator 6
<p>Compound Z10 (PKM2 activator 6) serves as both a PKM2 activator and a PDK1 inhibitor, exhibiting dissociation constants (K D ) of 121 μM and 19.6 μM,</p>Forma y color:Odour SolidChrysophanol triglucoside
CAS:<p>Chrysophanol triglucoside from Cassia obtusifolia, blocks PTP1B (IC50 80.17μM) & α-glucosidase (IC50 197.06μM), may aid diabetes study.</p>Fórmula:C33H40O19Forma y color:SolidPeso molecular:740.664α-2,3-Sialyltransferase (PmST3)
CAS:<p>PmST3 is a beta-galactoside enzyme adding sialic acid to glycoproteins and glycolipids.</p>Forma y color:SolidAxl-IN-16
<p>Axl-IN-16, a dual Axl/HIF inhibitor, promotes Flammulina velutipes fruiting body formation and suppresses hypoxia-inducible factor activity along with receptor</p>Fórmula:C14H19ClO8Pureza:98%Forma y color:SolidPeso molecular:350.75
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