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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8626 productos de "Metabolismo"

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  • PDE1-IN-5


    <p>PDE1-IN-5 (Compound 10c) is a selective PDE1C inhibitor with an IC50 of 15 nM, exhibiting anti-inflammatory properties through the inhibition of iNOS, TNF-α, IL</p>
    Fórmula:C27H29FN4O
    Forma y color:Solid
    Peso molecular:444.54
  • DSPE-PEG2000-R6H4


    <p>DSPE-PEG2000-R6H4 is a PEG compound composed of DSPE and a pH-responsive cell-penetrating peptide (R6H4). The R6H4 component is utilized for pH-responsive anticancer drug delivery. Additionally, DSPE-PEG2000-R6H4 is applicable in drug delivery systems.</p>
    Forma y color:Odour Solid
  • (1S,2R)-Globalagliatin

    CAS:
    <p>(1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.</p>
    Fórmula:C28H37N3O3S3
    Pureza:99.09% - >99.99%
    Forma y color:Soild
    Peso molecular:559.81
  • PPARγ-IN-3


    <p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>
    Fórmula:C23H28FN7O3
    Forma y color:Solid
    Peso molecular:469.51
  • Amiquinsin hydrochloride monohydrate

    CAS:
    <p>Amiquinsin hydrochloride monohydrate is a compound known for its antihypertensive activity. It undergoes metabolism in the body, with its primary metabolite being 4-amino-6,7-dimethoxy-3-quinolineol hydrochloride monohydrate.</p>
    Fórmula:C11H15ClN2O3
    Forma y color:Solid
    Peso molecular:258.7
  • Impurity B of Calcitriol

    CAS:
    <p>Impurity B is a byproduct of Calcitriol, the active hormone form of vitamin D3 and VDR activator.</p>
    Fórmula:C27H44O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:416.64
  • DSPE-PEG3000-R6H4


    <p>DSPE-PEG3000-R6H4 is a PEG compound composed of DSPE and the pH-responsive transmembrane peptide (R6H4). R6H4 is applicable for pH-responsive anticancer drug delivery. DSPE-PEG3000-R6H4 can be utilized for drug delivery purposes.</p>
    Forma y color:Odour Solid
  • Octocog alfa

    CAS:
    <p>Octocog alfa, a second-generation, full-length recombinant antihemophilic factor VIII (AHF), is utilized for the treatment of Hemophilia A [1].</p>
    Forma y color:Solid
  • 10 FTHF disodium

    CAS:
    <p>10 FTHF disodium (10-Formyltetrahydrofolic acid disodium) is a form of tetrahydrofolate that is involved in the synthesis of purine compounds.</p>
    Fórmula:C20H21N7Na2O7
    Forma y color:Solid
    Peso molecular:517.4
  • WH-15

    CAS:
    <p>WH-15: fluorogenic reporter for PLC-γ1, PLC-δ1, PLC-β2 with Km values of 49; 30, 86.1 µM. Cleaves to fluorescent 6-aminoquinoline for live cell imaging.</p>
    Fórmula:C31H43N2O18P3
    Forma y color:Solid
    Peso molecular:824.6
  • AH078


    <p>AH078 (compound 37) is a selective PROTAC degrader targeting CK1δ and CK1ε with low selectivity for CK1α. AH078 consists of a PROTAC linker (black part) Monomethyl octanoate, a target protein ligand (red part) CK1δ/CK1ε ligand-1, and an E3 ligase ligand (blue part) E3 Ligase Ligand 58. The E3 ligase ligand combined with the linker forms the conjugate E3 Ligase Ligand-linker Conjugate 163.</p>
    Fórmula:C51H60F2N10O5S
    Forma y color:Solid
    Peso molecular:963.15
  • Moth Cytochrome C (MCC) (88-103)

    CAS:
    <p>Moth Cytochrome C (88-103) peptide induces positive TCR selection in thymocytes; key for self-tolerant T cell development.</p>
    Fórmula:C79H133N23O25
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1805.04
  • Micafungin metabolite M1

    CAS:
    <p>Micafungin metabolite M1 is an active metabolite of Micafungin, generated through metabolism by arylsulfatase, and exhibits antifungal activity. It can be utilized in research on deep fungal infections caused by Candida species (Candidiasis) and Aspergillus species (Aspergillosis).</p>
    Fórmula:C56H71N9O20
    Forma y color:Solid
    Peso molecular:1190.21
  • BDM_92499


    <p>BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.</p>
    Forma y color:Odour Solid
  • Thymidine 5′-diphosphate

    CAS:
    <p>Thymidine 5′-diphosphate (dTDP), a crucial product of pyrimidine synthesis in organisms, is synthesized through the thymidylate kinase (TMPK)-catalyzed</p>
    Fórmula:C10H16N2O11P2
    Forma y color:Solid
    Peso molecular:402.19
  • Galactokinase (BiGalK)

    CAS:
    <p>Galactokinase (BiGalK), a phosphotransferase, catalyzes the ATP-dependent phosphorylation of α-D-galactose to galactose 1-phosphate [1].</p>
    Forma y color:Solid
  • MAHMA NONOate

    CAS:
    <p>MAHMA NONOate is a pH-dependent NO donor.MAHMA NONOate inhibits collagen or ADP-induced platelet aggregation.</p>
    Fórmula:C8H20N4O2
    Pureza:≥98%
    Forma y color:Solid
    Peso molecular:204.27
  • FA-Ala-Arg

    CAS:
    <p>FA-Ala-Arg is a dipeptide featuring a furylacryloyl group that degrades to yield arginine.</p>
    Fórmula:C16H23N5O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:365.38
  • Clostripain

    CAS:
    <p>Clostripain is a protease from Clostridium with esterase, amidase activities, targeting arginine.</p>
    Forma y color:Solid
  • Thalifendine chloride

    CAS:
    Thalifendine chloride is a metabolite of berberine,the methoxy group at the C-10 position undergoes demethylation by CYP51. cytotoxicity against P-388 cells.
    Fórmula:C19H16ClNO4
    Forma y color:Solid
    Peso molecular:357.79
  • 6-hydroxy Chlorzoxazone

    CAS:
    <p>6-hydroxy Chlorzoxazone, a chlorzoxazone metabolite, is formed in the liver via CYP2E1.</p>
    Fórmula:C7H4ClNO3
    Forma y color:White To Pink
    Peso molecular:185.56
  • 9AzNue5Ac

    CAS:
    <p>9AzNue5Ac is a Neu5Ac analog that is metabolized in vivo in living cells and in mice.9AzNue5Ac binds to sialoglycans.</p>
    Fórmula:C11H18N4O8
    Pureza:≥98%
    Forma y color:Solid
    Peso molecular:334.28
  • Diaphorase

    CAS:
    <p>Diaphorase from anaerobic sludge catalyzes RDX biotransformation via denitrification.</p>
    Forma y color:Solid
  • hCA/VEGFR-2-IN-2


    <p>Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and</p>
    Fórmula:C23H26N6O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:498.55
  • Impurity C of Alfacalcidol

    CAS:
    <p>Impurity of Alfacalcidol is an impurity of Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.</p>
    Fórmula:C35H49N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:575.78
  • FCPR03

    CAS:
    <p>FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively.</p>
    Fórmula:C15H19F2NO3
    Pureza:99.94%
    Forma y color:Solid
    Peso molecular:299.31
  • Seco Rapamycin ethyl ester


    <p>Seco Rapamycin ethyl ester, an open-ring metabolite of the Rapamycin derivative, reportedly does not impact mTOR function [1].</p>
    Fórmula:C53H83NO13
    Forma y color:Solid
    Peso molecular:942.23
  • C2 L-threo Ceramide (d18:1/2:0)

    CAS:
    <p>C2 L-threo Ceramide is a sphingolipid that modulates cholesterol in cells and affects IL-4, cell cycle, and leukemia cell growth.</p>
    Fórmula:C20H39NO3
    Forma y color:Solid
    Peso molecular:341.53
  • Vitamin K5

    CAS:
    <p>Vitamin K5, a photosensitizer &amp; antimicrobial, inhibits PKM2, PKM1 &amp; PKL, induces apoptosis in colon cells, and preserves food &amp; medicine.</p>
    Fórmula:C11H11NO
    Forma y color:Solid
    Peso molecular:173.21
  • α-Pyrone

    CAS:
    <p>Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9</p>
    Fórmula:C5H4O2
    Forma y color:Solid
    Peso molecular:96.08
  • CBS-1114 HCl

    CAS:
    <p>CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.</p>
    Fórmula:C13H14ClN3
    Pureza:99.36%
    Forma y color:Soild
    Peso molecular:247.72
  • Bacterial α-Amylase

    CAS:
    <p>Bacterial α-Amylase is an enzyme that catalyzes the hydrolysis reaction of starch into smaller sugar molecules such as maltose and glucose.</p>
    Forma y color:Solid
  • Evinacumab

    CAS:
    <p>Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases.</p>
    Pureza:100% (SEC-HPLC) - 99.43% (SEC-HPLC)
    Forma y color:Liquid
    Peso molecular:145.5 kDa
  • α-Lactose hydrate

    CAS:
    <p>α-Lactose (hydrate) (α-D-Lactose (hydrate)), the main carbohydrate in mammalian milk, comprises two sugar units: glucose and galactose, and occurs as two</p>
    Fórmula:C12H24O12
    Forma y color:Solid
    Peso molecular:360.31
  • DSPE-PEG2000-CREKA


    <p>DSPE-PEG3000-CREKA is a PEG compound composed of DSPE and the fibrin-targeting peptide (CREKA). The CREKA peptide targets tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3000-CREKA is useful in drug delivery applications.</p>
    Forma y color:Odour Solid
  • Boc-L-aspartic acid 4-benzyl ester

    CAS:
    <p>Boc-L-aspartic acid 4-benzyl ester (Boc-Asp(OBzl)-OH) is an aspartic acid derivative.</p>
    Fórmula:C16H21NO6
    Pureza:99.57%
    Forma y color:Solid
    Peso molecular:323.34
  • D-Threonine

    CAS:
    <p>D-Threonine (H-D-Thr-OH) is one of the metabolites of Saccharomyces cerevisiae.</p>
    Fórmula:C4H9NO3
    Pureza:≥98%
    Forma y color:Solid
    Peso molecular:119.12
  • MK-8245 Trifluoroacetate

    CAS:
    <p>MK-8245 trifluoroacetate: Potent liver-targeting SCD inhibitor, IC50=1nM (human). Anti-diabetic/anti-dyslipidemic. Selective, with low adverse event exposure.</p>
    Fórmula:C19H17BrF4N6O6
    Forma y color:Solid
    Peso molecular:581.27
  • FZQ-21


    <p>FZQ-21 (Compound 70P) is an inhibitor of the water-soluble epoxide hydrolase (sEH), with an IC50 value of 4 nM. The IC50 for inhibiting human sEH is 1.5 nM, which is comparable to that of EC5026 (1.7 nM). FZQ-21 is utilized in sepsis research.</p>
    Fórmula:C28H30N4O3
    Peso molecular:470.23179
  • L-Hisidine monohydrocholoride

    CAS:
    <p>L-Hisidine is an essential amino acid for infants and acts as an inhibitor of mitochondrial glutamine transport.</p>
    Fórmula:C6H10ClN3O2
    Forma y color:Solid
    Peso molecular:191.62
  • Lysylglutamic acid

    CAS:
    <p>Lysylglutamic acid is a dipeptide composed of the amino acids lysine (Lysine, Lys) and glutamic acid (Glutamic acid, Glu), with an inhibitory constant (Ki) of 1.3 mM for the membrane transport protein PEPT1.</p>
    Fórmula:C11H21N3O5
    Forma y color:Solid
    Peso molecular:275.3
  • NAADP sodium


    <p>NAADP sodium is a Ca2+ motor second messenger that targets Ca(2+) channels and can be used to study cancer and immune dysfunction.</p>
    Fórmula:C21H27N6O18P3
    Forma y color:Solid
    Peso molecular:744.39
  • SKI2852

    CAS:
    <p>SKI2852 is an 11β-HSD1 inhibitor that improves metabolic syndrome in diabetic mouse models.</p>
    Fórmula:C27H34FN5O4S
    Pureza:99.89%
    Forma y color:Solid
    Peso molecular:543.65
  • Nordoxepin hydrochloride

    CAS:
    <p>Nordoxepin hydrochloride (Desmethyldoxepin hydrochloride) has antidepressant activity and is useful for studying depression and peptic ulcer disease.</p>
    Fórmula:C18H20ClNO
    Pureza:99.49%
    Forma y color:Solid
    Peso molecular:301.81
  • PAz-PC

    CAS:
    <p>PAz-PC (Azelaoyl PC) is a truncated phospholipid oxidation product that enhances endothelial barrier disruption caused by HKSA.</p>
    Fórmula:C33H64NO10P
    Forma y color:Solid
    Peso molecular:665.84
  • 11(R)-HETE

    CAS:
    <p>11(R)-HETE aids in oocyte maturation in sea urchins and tentacle regeneration in hydras; it is also made by aspirin-influenced COX-2 and arachidonic acid.</p>
    Fórmula:C20H32O3
    Forma y color:Solid
    Peso molecular:320.473
  • Pantothenoylcysteine

    CAS:
    <p>Pantothenoylcysteine is a bioactive chemical.</p>
    Fórmula:C12H22N2O6S
    Forma y color:Solid
    Peso molecular:322.38
  • L-Cysteine-glutathione disulfide

    CAS:
    <p>L-Cysteine-glutathione disulfide is a biomarker for curing tuberculosis, useful in researching acetaminophen-induced liver toxicity.</p>
    Fórmula:C13H22N4O8S2
    Forma y color:Solid
    Peso molecular:426.47
  • SH7s


    <p>SH7s is an effective carbonic anhydrase inhibitor, exhibiting Ki values of 15.9 nM for hCA IX and 55.2 nM for hCA XII. Additionally, SH7s acts as a hypoxia-mediated chemosensitizer in colorectal cancer cells.</p>
    Fórmula:C24H19ClF3N5O4S
    Forma y color:Solid
    Peso molecular:565.95
  • (Z)-2-Octenoic acid

    CAS:
    <p>Z-2-Octenoic acid, the Z-isomer of 2-Octenoic acid, is also known as trans-2-Octenoic acid and serves as a metabolite in Mucor species.</p>
    Fórmula:C8H14O2
    Forma y color:Solid
    Peso molecular:142.20