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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

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Se han encontrado 8597 productos de "Metabolismo"

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  • A 78773

    CAS:
    <p>A 78773: potent reversible 5-lipoxygenase inhibitor; active in cells/tissues; targets inflammation, asthma, IBD.</p>
    Fórmula:C15H13FN2O4
    Forma y color:Solid
    Peso molecular:304.27
  • Mutant IDH1-IN-4

    CAS:
    <p>Mutant IDH1-IN-4 is an mutant Isocitrate dehydrogenase 1 (IDH 1) inhibitor.</p>
    Fórmula:C25H34N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:438.56
  • BMS-986318

    CAS:
    <p>BMS-986318: potent FXR agonist, EC50=53/350 nM, good ADME, effective in liver disease models, for nonalcoholic steatohepatitis research.</p>
    Fórmula:C30H23Cl2F3N4O3
    Forma y color:Solid
    Peso molecular:615.43
  • MK-0736

    CAS:
    <p>MK-0736 is a potent and selective 11β-HSD-1 inhibitor.</p>
    Fórmula:C23H30F3N3O2S
    Forma y color:Solid
    Peso molecular:469.56
  • SMS1-IN-1

    CAS:
    <p>SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies.</p>
    Fórmula:C23H23BrN2O4S
    Pureza:99.81%
    Forma y color:Solid
    Peso molecular:503.41
  • BAY-7081


    <p>BAY-7081 is a cyanopyridone-based compound that functions as a potent, selective, and orally active PDE9A inhibitor, demonstrating an inhibition concentration (</p>
    Fórmula:C19H27ClN4O
    Forma y color:Solid
    Peso molecular:362.9
  • GPX4-IN-2

    CAS:
    <p>GPX4-IN-2 is a potent inhibitor of GPX4, exhibiting antiproliferative activity. It holds potential for cancer research applications.</p>
    Fórmula:C30H40N2O
    Forma y color:Solid
    Peso molecular:444.65
  • 5α-Androst-16-en-3-one

    CAS:
    <p>5α-Androst-16-en-3-one, a mammalian pheromone present in boar saliva, plays a crucial role in facilitating social and sexual interactions by acting as a volatile chemical cue. It is utilized to prime sows in estrus for mating or artificial insemination, underscoring its significance in reproductive behavior. Additionally, this compound is detected in human sweat and urine, where it is involved in studies concerning receptor-mediated odorant detection and the genetic foundations of anosmias, thereby broadening its scope of relevance beyond the animal kingdom.</p>
    Fórmula:C19H28O
    Forma y color:Solid
    Peso molecular:272.432
  • BMS-962212

    CAS:
    <p>BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.</p>
    Fórmula:C32H28ClFN8O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:659.07
  • 4BAB

    CAS:
    <p>4BAB (compound 29) is an irreversible inhibitor of glyoxalase I (GLO1) and exhibits anticancer activity.</p>
    Fórmula:C18H28BrN3O10S
    Forma y color:Solid
    Peso molecular:558.4
  • Aladotrilat

    CAS:
    <p>Aladotrilat is an inhibitor of neutral endopeptidase. Its prodrug is aladrotril.</p>
    Fórmula:C14H17NO5S
    Forma y color:Solid
    Peso molecular:311.35
  • Tiracizine HCl

    CAS:
    <p>Tiracizine HCl, a new class I antiarrhythmic drug, was studied in patients with ischemic heart disease and shown to decrease myocardial contractile function.</p>
    Fórmula:C21H26ClN3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:403.9
  • Dasatinib analog-1

    CAS:
    <p>Dasatinib analog-1 (compound 5826) demonstrates inhibition of CYP3A4 activity, presenting a K_i value of 5.4 μM, and effectively prevents the formation of glutathione adducts [1].</p>
    Fórmula:C22H25ClFN7O2S
    Forma y color:Solid
    Peso molecular:506
  • 11β-13,14-dihydro-15-keto Prostaglandin F2α

    CAS:
    <p>11β-13,14-Dihydro-15-keto PGF2α, a PGD2 metabolite in the 15-hydroxy PGDH pathway, is formed in human males upon infusion or inhalation of tritiated PGD2, with peak plasma levels of both 11β-PGF2α and 11β-13,14-dihydro-15-keto PGF2α observed within 10 minutes. In human lung homogenates, PGD2 is metabolized firstly to 11β-PGF2α and subsequently to 11β-15-keto-PGF2α in the presence of NAD+, but not to 11β-13,14-dihydro-15-keto PGF2α. Conversely, guinea pig liver and kidney homogenates can metabolize PGD2 to 11β-13,14-dihydro-15-keto PGF2α via 11β-PGF2α, with both NAD+ and NADP+ being requisite for this conversion.</p>
    Fórmula:C20H34O5
    Forma y color:Solid
    Peso molecular:354.5
  • Arbaprostil

    CAS:
    <p>Arbaprostil, a synthetic PGE analog, guards stomach lining, aids ulcer healing, and blocks pancreatic function and tumor growth.</p>
    Fórmula:C21H34O5
    Forma y color:Solid
    Peso molecular:366.49
  • RORγt agonist 3

    CAS:
    <p>RORγt agonist 3 is a potent agonist of RORγt.</p>
    Fórmula:C34H37N3O3S
    Forma y color:Solid
    Peso molecular:567.74
  • AS 183

    CAS:
    <p>AS 183 is an inhibitor of cholesterol acyltransferase (ACAT).</p>
    Fórmula:C19H34O3
    Forma y color:Solid
    Peso molecular:310.47
  • CAY10632

    CAS:
    <p>Very long chain polyunsaturated fatty acids (VLCPUFA), notably present in the retina, sperm, and brain, have yet to be fully understood in terms of their biosynthesis and functional roles within these tissues. Recent research, particularly with the elongation of very long-chain FA-4 protein, indicates a distinct function for VLCPUFAs in retinal development and the progression of macular degeneration. CAY10632, a specific C32:6 VLCPUFA, while largely unexplored in its biological activities, is believed to play a role in maintaining normal function of photoreceptor cells in the retina.</p>
    Fórmula:C32H52O2
    Forma y color:Solid
    Peso molecular:468.766
  • C22 Phytoceramide (t18:0/22:0)

    CAS:
    <p>C22 Phytoceramide (t18:0/22:0) is a lipid molecule that can be used in life science related research. The CAS number of C22 Phytoceramide (t18:0/22:0) is 164576-03-8.</p>
    Fórmula:C40H81NO4
    Forma y color:Solid
    Peso molecular:640.1
  • 7,12-Diketolithocholic Acid

    CAS:
    <p>7,12-Diketolithocholic acid, a bile acid, exhibits elevated plasma levels in patients experiencing cholestasis.</p>
    Fórmula:C24H36O5
    Forma y color:Solid
    Peso molecular:404.54