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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

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Se han encontrado 8626 productos de "Metabolismo"

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  • Dihydrokainic acid

    CAS:
    EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
    Fórmula:C10H17NO4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:215.25
  • sEH inhibitor-2


    <p>SEH inhibitor-2 is an orally active sEH blocker (IC50=0.9 nM) with predicted 71.2-88.4% absorption, potentially aiding cardiovascular health.</p>
    Fórmula:C23H18N4O3
    Forma y color:Solid
    Peso molecular:398.41
  • Complex III-IN-1


    <p>Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.</p>
    Fórmula:C14H20ClNO2S2
    Forma y color:Solid
    Peso molecular:333.9
  • GlcCer (d18:1/18:0)

    CAS:
    <p>GlcCer (d18:1/18:0) (C18 Glucosyl(β) ceramide (d18:1/18:0)) is a sphingolipid with potential applications in research on Parkinson's disease and Lewy body dementia.</p>
    Fórmula:C42H81NO8
    Forma y color:Solid
    Peso molecular:728.094
  • HIF-1/2α-IN-1


    <p>HIF-1/2α-IN-1, an orally active compound, functions as an inhibitor of HIF-2α.</p>
    Fórmula:C17H16N6O4
    Forma y color:Solid
    Peso molecular:368.35
  • Pyrocatechol sulfate

    CAS:
    <p>Pyrocatechol sulfate, a phenolic metabolite found in human plasma, is associated with the intake of specific foods such as berries and the state of the gut microbiome. It serves as a potential urinary biomarker for kidney function, dialysis clearance rates, whole grain consumption, and regular coffee intake. Additionally, in conjunction with other phenolic sulfates, pyrocatechol sulfate plays a role in regulating various biological functions, including those related to brain health and the rhythmic beating of cardiac cells.</p>
    Fórmula:C6H6O5S
    Forma y color:Solid
    Peso molecular:190.17
  • α-Glucosidase-IN-15


    <p>α-Glucosidase-IN-15 (Compound 14B) exhibits potent inhibitory activity against α-glucosidase, with an IC50 value of 3.34 μM.</p>
    Fórmula:C24H24N2S
    Forma y color:Solid
    Peso molecular:372.53
  • SMase-IN-1

    CAS:
    <p>SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase (SMase) inhibitor with an IC50 value of 6.43 µM against Bacillus cereus SMase. It also inhibits eqBuChE with an inhibition rate of 59.50% at a concentration of 50 µM. SMase-IN-1 forms a complex with Cu2+ through bio-metal interactions and can inhibit hemolysis of sheep red blood cells induced by Bacillus cereus.</p>
    Fórmula:C8H5ClN2OS
    Forma y color:Solid
    Peso molecular:212.656
  • GW461484A

    CAS:
    <p>GW461484A is a small molecule inhibitor targeting Candida albicans Yck2, exhibiting an IC50 of 0.11 µM. It has a MIC80 of 12.5 µM against C. albicans. GW461484A shows potential for research into fungal diseases, including drug-resistant Candida infections.</p>
    Fórmula:C19H14FN3
    Forma y color:Solid
    Peso molecular:303.333
  • Etamicastat

    CAS:
    <p>Etamicastat can be used in the research of cardiovascular diseases.</p>
    Fórmula:C14H15F2N3OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:311.35
  • EpoY

    CAS:
    EpoY (SD-142) is an irreversible inhibitor of the primary brain microtubule-associated tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and small vasohibin-binding protein (SVBP). By inhibiting TCP with an IC50 value of approximately 500 nM, EpoY effectively reduces the levels of detyrosinated α-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition results in significant differentiation defects and is linked to potential issues related to cancer and cardiomyopathy.
    Fórmula:C15H17NO7
    Forma y color:Solid
    Peso molecular:323.30
  • α-Glucosidase-IN-18


    <p>α-Glucosidase-IN-18 (7B) is an orally active inhibitor of α-glucosidase, displaying an IC 50 value of 3.96 μM.</p>
    Fórmula:C23H19NO2S
    Forma y color:Solid
    Peso molecular:373.47
  • A-800141

    CAS:
    <p>A-800141 is an orally active and selective MetAP2 inhibitor with an IC50 of 12 nM, while showing weaker inhibitory activity against MetAP1 (IC50: 36 μM). GAPDH can serve as a biomarker for monitoring the inhibition of MetAP2 by A-800141. This compound exhibits anti-angiogenic and anticancer properties in various xenograft tumor models.</p>
    Fórmula:C24H30N2O4S
    Forma y color:Solid
    Peso molecular:442.571
  • (3S,17S)-FD-895

    CAS:
    <p>(3S,17S)-FD-895 is an analogue of FD-895. It inhibits the growth of HCT116 cells and shows splicing-modulating activity. This compound can be utilized in cancer research.</p>
    Fórmula:C31H50O9
    Forma y color:Solid
    Peso molecular:566.723
  • MRS4458

    CAS:
    <p>MRS4458 is an effective inhibitor of the P2Y14 Receptor.</p>
    Fórmula:C24H20F3N5O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:515.51
  • PDHK-IN-5


    <p>PDHK-IN-5, potent PDHK2 (0.006 μM IC50) &amp; PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.</p>
    Fórmula:C30H31N5O2
    Forma y color:Solid
    Peso molecular:493.6
  • Etiocholanolone glucuronide

    CAS:
    <p>Etiocholanolone glucuronide (Etio-G) is a metabolite of Etiocholanolone, produced through the catalysis by UDP glucuronosyltransferase in the liver. Etiocholanolone glucuronide shows potential for research in metabolic-related diseases.</p>
    Fórmula:C25H38O8
    Forma y color:Solid
    Peso molecular:466.564
  • CK1δ-IN-8

    CAS:
    <p>CK1δ-IN-8 (Compound 429) is a CK1δ inhibitor suitable for Alzheimer's disease research.</p>
    Fórmula:C14H9N3O2S2
    Forma y color:Solid
    Peso molecular:315.37
  • Casein kinase 1δ-IN-30

    CAS:
    <p>Casein kinase1δ-IN-30 (Compound 581) is an inhibitor of casein kinase 1δ (CK1δ). It can be utilized in research related to neurodegenerative diseases.</p>
    Fórmula:C18H15BrN6O2S
    Forma y color:Solid
    Peso molecular:459.32
  • P053

    CAS:
    <p>P053: potent, selective CerS1 inhibitor, IC50 = 0.5µM, curbs muscle fat oxidation, affects body fat.</p>
    Fórmula:C18H21Cl2NO2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:354.27