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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8626 productos de "Metabolismo"

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  • α-Glucosylrutin

    CAS:
    <p>α-Glucosylrutin is an effective antioxidant known for its activity in scavenging free radicals. Due to its high epidermal bioavailability, it is commonly utilized in studies related to skin aging.</p>
    Fórmula:C33H40O21
    Forma y color:Solid
    Peso molecular:772.66
  • α-Glucosidase-IN-17

    CAS:
    <p>α-Glucosidase-IN-17 (Compound 12B) is a potent and orally active inhibitor of α-glucosidase, demonstrating antidiabetic activity with an inhibitory</p>
    Fórmula:C30H27NO2S
    Forma y color:Solid
    Peso molecular:465.61
  • BAY-179

    CAS:
    <p>BAY-179 is a potent, selective, species cross-reactive complex I inhibitor for the study of cancer.</p>
    Fórmula:C23H21N5OS
    Pureza:98.29%
    Forma y color:Solid
    Peso molecular:415.51
  • PF-00489791

    CAS:
    <p>PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.</p>
    Fórmula:C20H28N8O4S
    Pureza:99.97%
    Forma y color:Solid
    Peso molecular:476.55
  • CYP11B1-IN-2


    <p>CYP11B1-IN-2 selectively inhibits human and rat CYP11B1 (IC50: 9/25 nM) orally to research cortisol-related diseases.</p>
    Forma y color:Solid
  • 2R,4S-Sacubitril

    CAS:
    <p>2R,4S-Sacubitril (Sacubitril Enantiomer) is the impurity of Sacubitril which is a neprilysin inhibitor.</p>
    Fórmula:C24H28NO51Ca
    Pureza:98%
    Forma y color:Solid
    Peso molecular:430.49
  • 11β-HSD2-IN-2

    CAS:
    <p>11β-HSD2-IN-2 (compound 3) is a selective 17β-HSD2 (17β-hydroxysteroid dehydrogenase type 2) inhibitor with an IC50 of 300 nM, studying osteoporosis.</p>
    Fórmula:C22H21NO2
    Pureza:99.61%
    Forma y color:Solid
    Peso molecular:331.41
  • Atorvastatin 3-Deoxyhept-2E-Enoic Acid

    CAS:
    <p>Atorvastatin 3-Deoxyhept-2E-Enoic Acid, an impurity in Atorvastatin, lowers blood lipids as an HMG-CoA reductase inhibitor.</p>
    Fórmula:C33H33FN2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:540.62
  • Propofol sulfate sodium

    CAS:
    <p>Propofolsulfate (sodium) is a metabolite of Propofol.</p>
    Fórmula:C12H17NaO4S
    Forma y color:Solid
    Peso molecular:280.316
  • MAGL-IN-15

    CAS:
    <p>MAGL-IN-15 (Compound 6), a MAGL inhibitor, holds potential for research into diseases and disorders associated with the regulation of endocannabinoid system signaling activities [1].</p>
    Fórmula:C16H16F6N4O3
    Forma y color:Solid
    Peso molecular:426.31
  • CK2-IN-3


    <p>CK2-IN-3: potent, selective CK2 inhibitor; Kd=12 nM, IC50: 1.51 μM (CK2α), 7.64 μM (CK2α'). For cancer research.</p>
    Fórmula:C22H26N4O7
    Forma y color:Solid
    Peso molecular:458.46
  • Mitapivat hydrochloride

    CAS:
    <p>Mitapivat (AG-348) hydrochloride is an orally active and selective allosteric activator of pyruvate kinase R (PK-R). It enhances the PK-R-catalyzed conversion of phosphoenolpyruvate to pyruvate, thereby promoting the glycolysis pathway, increasing ATP production in red blood cells, and decreasing 2,3-diphosphoglycerate (2,3-DPG) levels. Mitapivat hydrochloride is being investigated for potential use in the study of pyruvate kinase deficiency and other anemia-related disorders.</p>
    Fórmula:C24H27ClN4O3S
    Forma y color:Solid
    Peso molecular:487.014
  • LXR agonist 2


    <p>LXR agonist 2 is a potent agonist of the LXR (liver X receptor). LXR agonist 2 stabilises NCOA1 (coactivator), which in turn agonises the LXR.</p>
    Fórmula:C35H40ClN3O3
    Forma y color:Solid
    Peso molecular:586.16
  • MDL-100240

    CAS:
    <p>MDL-100240 inhibits ACE/neprilysin, effective against hypertension-induced heart/vascular changes.</p>
    Fórmula:C26H28N2O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:480.58
  • Fmoc-NH-PEG6-alcohol

    CAS:
    <p>Fmoc-NH-PEG6-alcohol, a cleavable ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs) [1].</p>
    Fórmula:C27H37NO8
    Forma y color:Solid
    Peso molecular:503.58
  • AXKO-0046


    <p>AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.</p>
    Fórmula:C25H33N3
    Forma y color:Solid
    Peso molecular:375.55
  • Lp(a)-IN-5

    CAS:
    <p>Lp(a)-IN-5 (Compound A) is an orally active inhibitor of lipoprotein (a) [Lp(a)]. It effectively inhibits the assembly of Apo(a) and ApoB proteins, with an IC50 value of 0.41 nM. Lp(a)-IN-5 shows potential for research into diseases associated with elevated plasma Lp(a) levels, such as cardiovascular diseases.</p>
    Fórmula:C43H56N4O7
    Forma y color:Solid
    Peso molecular:740.927
  • Carbonic anhydrase inhibitor 8


    <p>R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).</p>
    Fórmula:C20H25N3O4S
    Forma y color:Solid
    Peso molecular:403.5
  • DEL-I25

    CAS:
    <p>DEL-I25 is an effective activator of GPX4 that protects cells from ferroptosis (iron-dependent cell death).</p>
    Fórmula:C21H23N5O3
    Forma y color:Solid
    Peso molecular:393.44
  • LXRα agonist 1

    CAS:
    <p>LXRα agonist 1 (Compound 40) is a selective activator of LXRα, with an EC50 of 42 nM, and also demonstrates some activation effects on LXRβ, with an EC50 of 266 nM. It promotes target gene transcription by stabilizing the ligand-binding domain (LBD) of LXRα. When combined with the Raf inhibitor Sorafenib, LXRα agonist 1 shows significant antitumor activity in liver cancer cells. This compound is applicable in research focused on lipotoxicity-related cancers.</p>
    Fórmula:C28H27N3O2
    Forma y color:Solid
    Peso molecular:437.533